Clinical trials: Cardiac Flow
Chronic Heart Failure, Hyperuricemia
Allopurinol in Chronic Heart Failure
The purpose of this study is to discover whether the inhibition of the xanthine oxidase with allopurinol leads to a reduction of the production of oxygen free radicals in patients with CHF and thereby improves characteristics of…
- Trial name
- NCT00997542
- Testing
- Allopurinol
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- National Heart and Lung Institute
Aortic Stenosis, Multi Vessel Coronary Artery Disease
The TransCatheter Valve and Vessels Trial
The trial objective is to investigate whether Fractional Flow Reserve (FFR)-Guided Percutaneous Coronary Intervention (PCI) and TransCatheter Aortic Valve Implantation (TAVI) strategy for treatment of multivessel disease and…
- Conditions
- Aortic Stenosis, Multi Vessel Coronary Artery Disease, TAVI, CABG
- Trial name
- TCW (NCT03424941)
- Testing
- FFR-guided PCI and TAVI, CABG and SAVR
- Where
- 20 sites in Austria, Denmark and 8 more
- Volunteers
- 172 people
- Sponsor
- Maatschap Cardiologie Zwolle
Coronary; Ischemic
Novel Adenosine-independent Index of Coronary Artery Stenosis Severity Resting Flow Reserve
This study will enroll patients who are referred for coronary angiography and require physiological assessment to see if the lesion can be treated as per the local standard of care. Approximately 92 participants will be enrolled.
- Trial name
- RFR (NCT03461705)
- Testing
- Volcano Verrata Pressure Wire, St. Jude Medical (SJM) Aeris Pressure Wire System
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Gastrointestinal Neoplasms
Cerebral Blood Flow During Propofol Anaesthesia
General anaesthesia often reduces blood pressure whereby blood flow to the brain and other vital organs may become insufficient. Thus, medicine is often administered during anaesthesia to maintain blood pressure.
- Trial name
- NCT02951273
- Testing
- Study of cerebral blood flow
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intravenous Fluids, Pharmacodynamics
Effect of Oral Water in Healthy Volunteers on Cardiac Output, Regional Flow and Microcirculation in Healthy Volunteers
Human digestive system physiologically ensures the absorption of oral water and hydration of the human body. Water is quickly absorbed by the digestive tract with a peak between 15 and 20 minutes.
- Conditions
- Intravenous Fluids, Pharmacodynamics, Fluid Therapy, Fluid Responsiveness
- Trial name
- WATERNAL (NCT05153837)
- Testing
- saline intravenous administration, oral water
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Coronary Atheroscleroses, Coronary Angiography
Risk Factors of Intermediate Coronary Lesion Progression
Coronary intermediate lesions generally refer to lumen narrowing with diameter stenosis% (DS%) between 50% and 70% on angiography.
- Trial name
- NCT03855436
- Where
- China
- Volunteers
- 1,389 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
The Study Focused on the Vascular Effects of Semaglutide in Both Diabetic and Non-diabetic Patients, Obesity &Amp; Overweight
Coronary Flow Reserve Changes After Semaglutide Treatment
The goal of this observational study is to learn about the effects of semaglutide to coronary artery flow in diabetic and non-diabetic patients.
- Trial name
- NCT07190144
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Ekrem Bilal Karaayvaz
Postoperative Delirium After On-pump Cardiac Surgery
Preoperative Transcranial Doppler as a Predictor for Delirium Following On-pump Cardiac Surgery
Postoperative delirium is an important problem in patients undergoing major cardiac surgery and associated with more complicated hospital course, increased hospital length of stay and total postoperative cost.
- Trial name
- NCT02478736
- Testing
- No actual intervention
- Where
- South Korea
- Volunteers
- 175 people
- Sponsor
- Yonsei University
HIV
Effects of Biktarvy on CFR in Stable HIV Patients
Bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) is a single pill regimen that was approved by the FDA in February 2018 for treatment of HIV. The marketed name of the drug is Biktarvy.
- Trial name
- BETTER (NCT03656783)
- Testing
- Biktarvy
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Brigham and Women's Hospital
Heart Failure
The AFteR Registry - Follow-up Study to Monitor the Efficacy and Safety of the Occlutech AFR in Heart Failure Patients
This study aims to monitor the safety and efficacy of Occlutech AFR device in patients with Heart Failure.
- Trial name
- AFR Registry (NCT04405583)
- Testing
- Occlutech Atrial Flow Regulator
- Where
- 36 sites in France, Germany and 6 more
- Volunteers
- 150 people
- Sponsor
- Occlutech International AB
Acute Kidney Injury, Children
Renal Oxygen Saturation and Its Association With Acute Renal Injury
Peri-operative renal dysfunction is a major mortality and morbidity cause following cardiac and major vascular surgery. Although several intra-operative strategies are proposed for better outcomes, no effective and fast resulting…
- Conditions
- Acute Kidney Injury, Children, Cardiac Surgery
- Trial name
- NCT03608956
- Where
- Turkey (Türkiye)
- Sponsor
- Marmara University
Coronary Artery Disease
Physio PCI: Impact of Coronary Angioplasty on Non-hyperaemic Pressure Ratio in Patients With Coronary Artery Disease
The use of intra coronary physiological assessment with fractional flow reserve (FFR) is nowadays the standard approach to define ischemia-inducing stenosis and guide myocardial revascularization strategy in patients with…
- Trial name
- NCT04679805
- Where
- United Arab Emirates
- Volunteers
- 3 people
- Sponsor
- Ceric Sàrl
Congestive Heart Failure
Atrial Flow Regulator in Heart Failure
The aim of the study is to assess invasive and non-invasive parameters that may predict clinical improvement in patients with congestive heart failure after implantation of Occlutech® Atrial flow regulator (AFR) device.
- Trial name
- PROLONGER (NCT04334694)
- Testing
- Atrial flow regulator (Occlutech® AFR device)
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Szpitale Pomorskie Sp. z o. o.
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Angiography-Derived Physiological Indices for Outcome Prediction in Patients Undergoing OCT-Guided PCI
The primary design of this study is an ambispective observational cohort study. In patients undergoing successful optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) with post-procedural…
- Trial name
- ADOPT-PCI (NCT07511231)
- Testing
- OCT-guided PCI
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Vasospasm
Effect of Glucose on Ocular Blood Flow
The primary objective is to assess the effect of glucose on retinal vascular diameter in otherwise healthy vasospastic subjects compared to non-vasospastic controls.
- Trial name
- NCT00350129
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Coronary Artery Disease
SPECT Myocardial Blood Flow Quantification for Diagnosis of Ischemic Heart Disease Determined by Fraction Flow Reserve
Recent evidences have demonstrated improved diagnostic accuracy for detecting coronary artery disease (CAD) when myocardial blood flow (MBF) is quantified in absolute terms using single photon emission tomography (SPECT) compared…
- Trial name
- NCT06030596
- Where
- China
- Volunteers
- 202 people
- Sponsor
- China National Center for Cardiovascular Diseases
Parkinson Disease, Orthostatic Hypotension
Cardiovascular Effects of Exercise in Patients With Parkinson's Disease
Abnormalities in the regulation of cardiovascular system due to autonomic nervous system (ANS) dysfunction may lead to a sudden decline in blood pressure (BP) upon standing, sitting or performing activities/exercises in patients…
- Trial name
- NCT03343574
- Testing
- Abdominal Strengthening Exercise
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Faizan Ahmed
Coronary Artery Disease, Myocardial Ischaemia
Coronary CT-Derived FFR-Guided Strategy Versus Medical Therapy
The overall purpose of ACCURATE II trial is to compare the clinical outcomes of CT-derived FFR guided strategy versus medical therapy in patients with chronic coronary syndrome.
- Trial name
- ACCURATE II (NCT05824520)
- Testing
- ITS plus OMT, OMT
- Where
- China
- Volunteers
- 1,066 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intestinal Blood Flow
Packed Red Blood Cell Transfusion and Intestinal Blood Flow in Preterm Neonates
The purpose of the study is to determine whether packed red blood cell (PRBC) transfusion affects intestinal blood flow of premature infants during feedings and if so, whether return of normal intestinal blood flow pattern occurs…
- Trial name
- NCT01628133
- Testing
- ultrasound
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- St. Louis University
Coronary Artery Disease
Registry of Patients That Have Undergone ICA or PCI
In Invasive Coronary Angiography there are multiple invasively obtained measurements to determine the funcitonal significance of Cornary Artery Disease.
- Trial name
- ICA-PI (NCT04815928)
- Where
- Netherlands
- Volunteers
- 10,000 people
- Sponsor
- Amsterdam UMC, location VUmc
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.