Clinical trials: Cardiac Health
Marfan Syndrome, Marfan Syndrome Cardiovascular Manifestations
Living With Marfans and Your Aorta: Surgical Outcomes Study
Marfan Syndrome (MFS) is a genetic disease affecting the eyes, skeleton, heart and arteries. Despite MFS affecting multiple organ systems, cardiovascular manifestations are the most serious and life threatening.
- Trial name
- LIMA II (NCT04776681)
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Barts & The London NHS Trust
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Malignant Neoplasm, Leukemia, Lymphocytic, Chronic, B-Cell
Project to Improve Communication About Serious Illness - Pilot Study
This two-year pilot study will test whether a one-page "Jumpstart Form" will affect goals-of-care discussions in the hospital. This form will be provided to clinicians and will include patient-specific information about…
- Conditions
- Malignant Neoplasm, Leukemia, Lymphocytic, Chronic, B-Cell, Lung Disease Chronic, Congestive Heart Failure
- Trial name
- PICSI-P (NCT03746392)
- Testing
- Jumpstart Intervention
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Washington
Acute Coronary Syndrome
Citalopram for Sx/Util in Acute Coronary Syndrome Patients
Symptoms (chest pain, shortness of breath, dizziness, etc.) and treatment usage (doctor or emergency room visits, testing, hospital days, etc.) in patients with Acute Coronary Syndromes are known to be related to emotional…
- Trial name
- NCT01667744
- Testing
- Citalopram
- Where
- United States
- Sponsor
- Henry Ford Health System
Cardiovascular Risk Factor, Cardiovascular Diseases
Umbrella Review of the DASH Dietary Pattern and Cardiometabolic Risk
The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding the Dietary Approaches to Stop Hypertension (DASH) diet, a dietary pattern that emphasizes fruits and…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Coronary Heart Disease, Stroke
- Trial name
- NCT03542370
- Testing
- DASH dietary pattern
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Heart Failure
Future Innovations in Novel Detection of Heart Failure FIND-HF
Heart failure (HF) is increasingly common and associated with excess morbidity, mortality and healthcare costs. New medications are now available which can alter the disease trajectory and reduce clinical events.
- Trial name
- FIND-HF (NCT05756127)
- Testing
- Observational - no intervention given
- Where
- United Kingdom
- Volunteers
- 14,000 people
- Sponsor
- University of Leeds
Heart Failure
Experience in Being With Advanced Heart Failure Patients
The purpose of this study is to explore the experience in being with advanced Heart failure patients.
- Trial name
- NCT02437331
- Where
- Taiwan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation
Predicting Patient-level New Onset Atrial Fibrillation
Atrial fibrillation (AF) is a major cardiovascular health problem: it is common, chronic and incurs substantial health-care expenditure as a result of stroke, sudden death, heart failure and unplanned hospitalisation.
- Trial name
- NCT04657900
- Testing
- Observational
- Where
- United Kingdom
- Volunteers
- 140,000 people
- Sponsor
- University of Leeds
Heart Transplant Patients, Kidney Transplant Patients
Multidisciplinary Non-Pharmacological Intervention to Improve Quality of Life in Solid Organ Transplant Recipients
This is a single-center interventional study aimed at evaluating the feasibility of a multidisciplinary non-pharmacological approach based on acupuncture, telerehabilitation-based physical rehabilitation, and brain health…
- Conditions
- Heart Transplant Patients, Kidney Transplant Patients, Lung Transplant, Liver Transplanted Patients
- Trial name
- TAO (NCT07870811)
- Testing
- Acupuncture, Telerehabilitation-Based Physical Rehabilitation, Psychological Support Program
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Cardiac Arrest, Therapeutic Hypothermia
SEVOflurane Inhalation in CARdiac Arrest Resuscitated Patients Treated With Therapeutic Hypothermia
Studying the feasibility of an initial sedation with inhalated sevoflurane during therapeutic hypothermia of cardiac arrests resuscitated patients.
- Trial name
- SEVOCAR (NCT02201134)
- Testing
- sevoflurane
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Failure
"A Nurse-led Motivational Interviewing Tailored Intervention for Improving Self Care Behaviours and Health Outcomes in Heart Failure Patients in Oman
This is a pilot randomized clinical trial that have employed a motivational interviewing intervention to enhance self-care in heart failure patients.
- Trial name
- MITI (NCT07721909)
- Testing
- Motivational interviewing, Standard Care (Treatment as Usual)
- Where
- Oman
- Volunteers
- 60 people
- Sponsor
- Sultan Qaboos University
Heart Failure With Reduced Ejection Fraction, HIV Infections
Heart Failure Polypill at a Safety Net Hospital
A novel four-drug regimen for heart failure with reduced ejection fraction (HFrEF) extends patients' life expectancy by an average of 6 years compared to traditional therapies, in addition to improving quality of life.
- Trial name
- NCT06029712
- Testing
- Heart failure polypill, Control Rx
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Francisco
Ventricular Assist Device, Self-management
Improved Self-management for Patients on Ventricular Assist Device (VAD)
The number of patients with end-stage heart disease requiring the implantation of ventricular assist devices (VAD) is steadily increasing.
- Conditions
- Ventricular Assist Device, Self-management, Psychological Factors
- Trial name
- SELMA (NCT04234230)
- Testing
- Prevalence Survey
- Where
- 4 sites in Germany
- Volunteers
- 393 people
- Sponsor
- University of Freiburg
Obesity, Depression
The Effect and Applicability of CBT-Based Weight Loss Treatment Model in Obese Patients With Comorbid Depression in Health Care
The aim of this study is find out how CBT-based weight loss program affects on eating behavior, weight loss, mood symptoms and risk for coronary heart diseases and type 2 diabetes and applicability of the program to obesity…
- Conditions
- Obesity, Depression, Cognitive Behavioral Therapy, Weight Loss
- Trial name
- PsyCognObe2 (NCT04513587)
- Testing
- CBT-based weight loss model, Control
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Kuopio University Hospital
Coronary Microvascular Disease
Exercise and Coronary Microvascular Disease
Exercise CMD is a prospective single-center, open-label, parallel arms randomized controlled trial. This trial aims to assess the impact of cardiac rehabilitation on top of optimal medical therapy on patient-reported outcomes in…
- Trial name
- ExerciseCMD (NCT05810051)
- Testing
- Cardiac rehabilitation
- Where
- Belgium
- Volunteers
- 204 people
- Sponsor
- CoreAalst BV
Mind-body Exercise, Vascular Health
the Effects of Different Exercise on Vascular Health
To explore the effect of smart app and wearable-based lifestyle intervention management on vascular health, comparing different exercise with the improvement of vascular arterial stiffness.
- Conditions
- Mind-body Exercise, Vascular Health, M-health, Cardiac Rehabilitation
- Trial name
- NCT06419751
- Testing
- Regular exercise, Baduanjin
- Volunteers
- 216 people
- Sponsor
- China National Center for Cardiovascular Diseases
ERAS, Cardiac Surgery
Impact of a Technology Platform Based on Enhanced Recovery After(ERAS) Surgery on Length of Stay After Coronary Artery Bypass Grafting: Timely Project
Cardiovascular diseases continue to be the leading cause of death worldwide. Among them, coronary artery disease has the greatest impact, being characterized as one of the main causes of death in Brazil over the last decade.
- Conditions
- ERAS, Cardiac Surgery, Cardiac Surgery-CABG, Digital Health
- Trial name
- REPLICCARIII (NCT06786819)
- Testing
- ERACS with Digital Platform
- Where
- 2 sites in Brazil
- Volunteers
- 480 people
- Sponsor
- University of Sao Paulo General Hospital
Vascular Ehlers-Danlos Syndrome
Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients
Vascular Ehlers-Danlos Syndrome (VEDS) is caused by pathogenic variants of the COL3A1 gene, resulting abnormal Type III collagen protein.
- Trial name
- NCT05994664
- Testing
- Heartmath Intervention, Control Group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Acute Coronary Syndrome
Rehabilitation Exercise With MObile Technology and Education After Acute Coronary Syndrome
Despite a clear indication of grade Ia, cardiac rehabilitation (CR) is dramatically underutilized after acute coronary syndrome with less than 30% of patients addressed in France.
- Trial name
- REMOTE-ACS (NCT05385341)
- Testing
- Telerehabilitation (Tele RCV), Rehabilitation (RCV)
- Sponsor
- University Hospital, Toulouse
Non ST Elevation Myocardial Infarction, Unstable Angina
Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients with Non ST Elevation Elevation Acute Coronary Syndrome
Background: Most coronary artery bypass grafts (CABG) are diseased or blocked within 10 years of surgery meaning CABG survivors have an ever increasing risk of recurrent angina, heart attack and death.
- Trial name
- CABG-ACS (NCT01895751)
- Testing
- Invasive management
- Where
- 5 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- NHS National Waiting Times Centre Board