Clinical trials: Cardiac Health
Vascular Death, Myocardial Infarction
Vascular Events In Surgery patIents cOhort evaluatioN - Cardiac Surgery
Worldwide over 2 million adults (>30,000 Canadians) undergo heart surgery annually. Although heart surgery provides important survival benefits, it is associated with potential major complications such as death, stroke, and heart…
- Conditions
- Vascular Death, Myocardial Infarction, Stroke, Cardiac Surgery
- Trial name
- NCT01842568
- Where
- 24 sites in United States, Australia and 10 more
- Volunteers
- 15,989 people
- Sponsor
- Population Health Research Institute
Cardiac Implantable Electronic Device Implantation
Educational Intervention for Elderly Patients With Cardiac Implantable Electronic Devices and Their Family Caregivers
This study evaluated whether a Family-Centered Empowerment Model could improve health status and functional independence and reduce complications in older adults after cardiac implantable electronic device (CIED) implantation.
- Trial name
- NCT07857915
- Testing
- Family-Centered Empowerment Model (FCEM), Routine Care
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Cardiovascular Diseases, Risk Reduction
Strategy for Cardiovascular Disease Prevention Through Tailored Health Management in Individuals With Elevated Risk
The China PEACE SMARTER trial is a cluster ramdomized trial aiming to assess the effectiveness of village doctor-led tailored health management on risk reduction of high-risk individuals for cardiovascular disease.
- Conditions
- Cardiovascular Diseases, Risk Reduction, Primary Prevention
- Trial name
- SMARTER (NCT05645640)
- Testing
- Village doctor-led tailored health management
- Where
- China
- Volunteers
- 4,533 people
- Sponsor
- China National Center for Cardiovascular Diseases
Heart Failure
SHARE Study: Social Chronic Heart Failure Person-centred cARE Intervention
People with Chronic Heart Failure (CHF) live with a complex situation that significantly affects their quality of life and well-being.
- Trial name
- SHARE (NCT06701916)
- Testing
- Intervention group., Usual care
- Where
- Spain
- Volunteers
- 374 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Physical Activity, Poor Quality Sleep
SMART Technology to Promote Heart Health in Midlife Adults
This study aims to increase weekly minutes of moderate-to-vigorous physical activity and improve sleep quality in a sample of mid-life adults between ages 50 and 64 years.
- Conditions
- Physical Activity, Poor Quality Sleep, Hypertension
- Trial name
- BeSMART (NCT03724474)
- Testing
- Be SMART
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Heart Disease, Cardiovascular Health Status
Pathways to Prevention Food-is-Medicine Trial
The goal of this study is to learn whether combining healthy food access with personalized tools can help families improve heart health and make lasting lifestyle changes.
- Trial name
- P2P (NCT07380243)
- Testing
- Nutrition Education, PRO-CVH, Healthy Conversation Skills
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Amrik Singh Khalsa
Coronary Heart Disease, Stroke
Examining the Long-Term Risks of Oophorectomy
At the time of hysterectomy for benign disease, the overall health benefits of preserving ovarian function in a large population of women have not been established.
- Conditions
- Coronary Heart Disease, Stroke, Breast Cancer, Ovarian Cancer
- Trial name
- NCT00655447
- Where
- United States
- Volunteers
- 32,175 people, healthy volunteers welcome
- Sponsor
- Parker, William H., M.D.
Coronary Artery Disease, Myocardial Infarction
Efficacy of the Integration of Digital Therapeutics and Home-based Cardiac Rehabilitation in High-Risk Post-PCI Patients
The DTx-HBCR trial will randomize 366 high-risk patients who undergo PCI at the West China Hospital of Sichuan University to either the 6-month DTx-guided HBCR group (intervention group) or the 6-months usual care group (control…
- Trial name
- NCT06542575
- Testing
- DTx-guided HBCR
- Where
- China
- Volunteers
- 366 people
- Sponsor
- West China Hospital
Atrial Fibrillation
APIXABAN App Study
The aim of this clinical trial is to evaluate whether the medication reminder app and video call can improve medication adherence to apixaban in patients with AF and comorbidities.
- Trial name
- NCT06903845
- Testing
- video call, Medication reminder app
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Dong-Ju Choi
Atrial Fibrillation (AF), Stroke
Population-based Atrial Fibrillation Screening in Individuals With NT-proBNP Above Median in the Tromsø Study
The aim is to investigate whether screening with long-term ECG monitoring in individuals with elevated NT-proBNP leads to a lower incidence of ischeamic stroke and death from vascular causes.
- Conditions
- Atrial Fibrillation (AF), Stroke, NT-pro-BNP, Cognitive Function and Well-Being
- Trial name
- PAFS-Tromsø (NCT07343895)
- Testing
- Long term heart rythm monitoring by ECG247
- Where
- 2 sites in Norway
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Diabetes, Myocardial Infarction
Look AHEAD: Action for Health in Diabetes
The Look AHEAD study is a multi-center, randomized clinical trial to examine the long-term effects of a lifestyle intervention designed to achieve and maintain weight loss.
- Conditions
- Diabetes, Myocardial Infarction, Stroke, Kidney Diseases
- Trial name
- LookAHEAD (NCT00017953)
- Testing
- Lifestyle Intervention, Diabetes Support and Education
- Where
- 18 sites in United States
- Volunteers
- 5,145 people
- Sponsor
- Wake Forest University Health Sciences
Menopause, Cardiac Function Impaired
Effects of Exercise Training on Cardiovascular Health in Middle-aged Women
The hypothesis of the present study is that physical training can oppose detrimental changes in cardiovascular and metabolic health associated with estrogen loss after menopause.
- Conditions
- Menopause, Cardiac Function Impaired, Cardiovascular Diseases, Blood Platelet Disorders
- Trial name
- NCT02135575
- Testing
- Spinning
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Coronary Artery Disease
Remote 3-week Booster Intervention to Reduce Sedentary Time in Patients With Coronary Artey Disease
The goal of this clinical trial is to learn about the effect of a booster program aiming to lower daily sitting time (SIT LESS Booster program) compared to usual care in patient with coronary heart problems.
- Trial name
- BOOSTSITLESS (NCT06038188)
- Testing
- SIT LESS Booster
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Radboud University Medical Center
Coronary Heart Disease, Depression
Depression Care for Hospitalized Coronary Heart Disease Patients: Prospective Cohort Study
The aims of this prospective, observational study are to assess the current use of depression care in Coronary Heart Disease (CHD) patients, and to provide estimates for the resources needed to implement guideline-oriented…
- Trial name
- CDCare (NCT01626027)
- Where
- Germany
- Volunteers
- 1,265 people
- Sponsor
- Charite University, Berlin, Germany
Acute Myocardial Infraction or Chest Pain, Chronic Obstructive Pulmonary Disease (COPD)
Developing Enhanced Prediction Models
In this study, patients will be prospectively enrolled for data collection to design prediction models that integrate claims data (inpatient, outpatient, and pharmacy), electronic health record data (on clinical, social, and…
- Conditions
- Acute Myocardial Infraction or Chest Pain, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure (CHF), Diabetes
- Trial name
- PREDICT (NCT02983812)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Pennsylvania
Hypertension, Diabetes Mellitus, Type 2
Enhancing Community Health Through Patient Navigation, Advocacy and Social Support
Some patients who have multiple long-term health conditions have significant challenges accessing needed services despite available primary care and social services resources.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Chronic Kidney Diseases, Ischemic Heart Disease
- Trial name
- ENCOMPASS (NCT03077386)
- Testing
- ENCOMPASS Intervention
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- University of Calgary
Health Promotion
Caregiver Stress: Interventions to Promote Health and Wellbeing
More and more family members are providing care to their loved ones with prolonged and progressive illnesses. Chronic intense caregiving represents a situation of chronic stress, which takes a toll on one's mental and physical…
- Trial name
- NCT01188070
- Testing
- Usual Care, Psycho-education, Psycho-education plus physical exercise
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Emory University
Cardiovascular Diseases, Coronary Artery Disease
Evaluation Using ClearView in Determining Association to the Cardiac Risk Factors
The objective of this study is to explore the relationship between the ClearView scan results and a variety of cardiovascular risk indicators such as the Coronary Calcium Score, Framingham Risk Factors, Reynolds Risk Score, and…
- Trial name
- Cardiac-CV (NCT01740739)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Epic Research & Diagnostics, Inc.
Heart Failure With Reduced Ejection Fraction (HFrEF), Sacubitril/Valsartan
Evaluating Dashboard-Integrated Pharmacist-Led Education on Improving Sacubitril/Valsartan Adherence in Heart Failure (PharmD ASSIST HFrEF)
The goal of this pragmatic clinical trial is to evaluate whether pharmacist-led education, integrated with interactive visualization dashboards, can enhance medication adherence in patients with heart failure who are prescribed…
- Conditions
- Heart Failure With Reduced Ejection Fraction (HFrEF), Sacubitril/Valsartan, Medication Adherence
- Trial name
- NCT06900803
- Testing
- interactive visualization dashboard (the Enhancing Sacubitril/valsartan Adherence from Initiation to Continuation [ESAIC] dashboard)
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Chronic Heart Failure, Chronic Kidney Diseases
ODYSSEE-vCHAT Mental Health Program for Heart Failure and Kidney Disease Patients
INTRODUCTION Psychological distress and reduced quality of life are prevalent in patients with chronic heart failure (CHF) and advanced chronic kidney disease (CKD).
- Trial name
- ODYSSEEvCHAT (NCT05560737)
- Testing
- ODYSSEE-vCHAT
- Where
- 4 sites in Canada
- Volunteers
- 215 people
- Sponsor
- University Health Network, Toronto
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