Clinical trials: Cardiac Health
Rheumatic Heart Disease
Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System
The first primary objective of this study is to determine the diagnostic performance (sensitivity and specificity) of primary MOH nurses who have completed certification in focused echocardiography acquisition and interpretation…
- Trial name
- ADD-RHD 2B (NCT05668611)
- Testing
- Primary Training Phase, Primary Assessment Phase, Primary Screening Phase
- Where
- Uganda
- Volunteers
- 1,628 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Lymphoma, Sarcoma
WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring)
The purpose of this study is to find a cost effective cardiovascular (CV) surveillance of cancer survivors over long periods of time to prevent the risk of progression of heart failure (HF) and related morbidity and mortality.
- Trial name
- NCT07058064
- Testing
- Electrocardiogram, Echocardiogram, LVEF echocardiogram
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Mayo Clinic
Worksite Health Promotion, Lifestyle Risk Reduction
Intervention to Increase Physical Activity and Wellbeing Among Staff and Residents in Assisted Living Facilities
The purpose of the study is to test a program that aims to help staff increase wellness behaviors and test the impact of this program on staff and work outcomes.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Occupational Burnout, Healthcare Workers
- Trial name
- WHHIP+FFC 2026 (NCT07785947)
- Testing
- WHHIP, FFC
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Myocardial Infarction (MI), Tobacco Use
Telegram Messenger Support for Smoking Cessation After Heart Attack
This randomized controlled trial will evaluate whether a 6-month behavioral intervention delivered via Telegram messenger increases smoking cessation rates in patients after myocardial infarction (MI).
- Conditions
- Myocardial Infarction (MI), Tobacco Use, Smoking Cessation
- Trial name
- TELEGRAM-MI (NCT07230249)
- Testing
- Telegram-based Smoking Cessation Support, Standard Care (in control arm)
- Where
- Russia
- Volunteers
- 142 people
- Sponsor
- ITMO University
Coronary Artery Disease
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Change in Cardiovascular Health
The goal of this randomized controlled trial is to assess the impact of disclosing a high polygenic risk result for coronary artery disease on change in cardiovascular health over one year.
- Trial name
- PROACT 1 (NCT05819814)
- Testing
- Disclosure of high polygenic risk result for coronary artery disease
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Cardiorespiratory Arrest, Cardiopulmonary Arrest With Successful Resuscitation
Effectiveness of Online Training in Cardiopulmonary Resuscitation Maneuvers for a Network of Volunteers.
Background: Cardiorespiratory arrest (CPA) occurs when there is a cessation of cardiac mechanical activity, typically diagnosed by the absence of consciousness, pulse, and breathing.
- Trial name
- EFORCP (NCT06275984)
- Testing
- online CPR-AED training
- Where
- Spain
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Heart Failure
TEC4Home Heart Failure: Using Home Health Monitoring to Support the Transition of Care
TEC4Home Heart Failure is a randomized controlled trial (RCT) that examines how home health monitoring (HHM) can support Heart Failure (HF) patients during the transition of care from hospital to home.
- Trial name
- TEC4Home (NCT03439384)
- Testing
- Home Telemonitoring
- Where
- Canada
- Volunteers
- 390 people
- Sponsor
- University of British Columbia
Muscle Weakness, Late Effect of Burn
Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients
This study will measure efficacy of early in-patient exercise as an adjunct to current Standard of Care (SOC) for 96 patients in a multi-centre trial.
- Conditions
- Muscle Weakness, Late Effect of Burn, Muscle; Fatigue, Heart, Burn Rehabilitation
- Trial name
- MP-10 (NCT02739464)
- Testing
- Exercise + SOC PT/OT, SOC PT/OT
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Heart Failure
Randomized Implementation of Routine Patient-Reported Health Status Assessment Among Heart Failure Patients in Stanford Cardiology
This randomized quality improvement study evaluates the routine assessment of patient-reported heath status, using the Kansas City Cardiomyopathy Questionnaire-12 (KCCQ-12) among adult outpatients seen in heart failure clinic or…
- Trial name
- NCT05564572
- Testing
- Routine Health Status Assessment
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Stanford University
Sleep
Investigating the Efficacy of Sleepgift Blanket on Sleep Quality and Heart Health
Exposure to electromagnetic field (EMF) emitted by mobile phones and devices with WIFI is on the rise and so is the EMF effects on sleep quality and well-being of individuals with high exposures to EMF.
- Trial name
- NCT05463302
- Testing
- Active sleepgift blanket
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Diet Modification, Physical Activity
Denver Garden Environment and Microbiome Study Disease
An interdisciplinary team with extensive garden study experience conducted a pilot randomized controlled clinical trial to see whether gardening reduced risk factors for diseases like cancer and heart disease.
- Conditions
- Diet Modification, Physical Activity, Weight Gain, Chronic Disease
- Trial name
- DGEM (NCT03089151)
- Testing
- Community Garden Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Hypertension, Diabetes
Wearable Devices Empowering Active Health Initiatives for High-Risk Stroke Populations
The purpose of this study is to evaluate the control effect of smart wearable devices on key risk factors in the high-risk populations for stroke
- Conditions
- Hypertension, Diabetes, Atrial Fibrillation, Dyslipidemia
- Trial name
- AISP (NCT06935513)
- Testing
- Wearable Devices
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Affiliated Hospital of Nantong University
Comorbidities and Coexisting Conditions, Ethics
eCardiacRehab - a Hybrid Patient-Centered eHealth Programme
The overall aim of eCardiacRehab trial is to meet rehabilitation needs of patients with coronary artery disease (CAD) regardless of their access to traditional place-based rehabilitation by developing and evaluating the efficacy…
- Conditions
- Comorbidities and Coexisting Conditions, Ethics, Continuity of Patient Care, Older Adults (65 Years and Older)
- Trial name
- eCardiacRehab (NCT07590635)
- Testing
- eCardiacRehab
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Haukeland University Hospital
Quality of Life, Cardiac Rehabilitation
Patient-Reported Outcome Measures in Cardiac Rehabilitation: Impact on Health Care
Cardiac Rehabilitation (CR) programs are a multidisciplinary process aimed at patient recovery after an acute cardiovascular event or with chronic heart disease, reducing mortality and morbidity, optimising functional capacity…
- Conditions
- Quality of Life, Cardiac Rehabilitation, Patient-Reported Outcome Measures, Rehabilitation Exercise
- Trial name
- PROM_R (NCT06032013)
- Testing
- Cardiac rehabilitation program (PROMs)
- Where
- Portugal
- Volunteers
- 5 people
- Sponsor
- José Manuel Afonso Moreira
Depression, Heart Failure, Congestive
Interpersonal Psychotherapy for Depression in People With Heart Failure
This study will evaluate the effectiveness of interpersonal psychotherapy and behavioral activation techniques in treating depression in people with congestive heart failure.
- Trial name
- NCT00353223
- Testing
- Interpersonal and behavioral psychotherapy, Attention control (AC) condition
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Iowa
Alzheimer Disease, Alzheimer Dementia
Alzheimer's Caregiver Coping: Mental and Physical Health
This study evaluates the effectiveness of Behavioral Activation (BA) therapy vs Support and Information for reducing risk for emotional and cardiovascular diseases in Alzheimer's caregivers.
- Conditions
- Alzheimer Disease, Alzheimer Dementia, Alzheimer's Disease, Dementia
- Trial name
- NCT02317523
- Testing
- Behavioral Activation, Information and Support
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- University of California, San Diego
Chronic Heart Failure
Dissertation Project Title: Effects of a Mindfulness-Based Intervention in Chronic Heart Failure
Patients with Chronic Heart Failure diagnosed and conventional treated, but still symptomatic (i.e. breathlessness, fatigue) is invited. Eligible patients are randomised to (1) care as usual (i.e.
- Trial name
- NCT04871178
- Testing
- Mindfulness-based intervention
- Volunteers
- 50 people
- Sponsor
- Göteborg University
Myocardial Infarction, Coronary Artery Disease
A Randomized Evaluation of First-dollar Coverage for Post-MI Secondary Preventive Therapies
The objective of this randomized trial is to evaluate the effect of providing full prescription drug coverage (i.e. no co-pays, co-insurance or deductibles) for statins, beta-blockers, angiotensin converting enzyme inhibitors and…
- Trial name
- MI FREEE (NCT00566774)
- Testing
- Full drug coverage, Usual coverage
- Where
- United States
- Volunteers
- 5,860 people
- Sponsor
- Brigham and Women's Hospital
Heart Failure
Effect of a Quality Improvement Initiative to Address Social Determinants of Health on Rehospitalization Rates in Patients With Heart Failure
The objective of this program is to improve post-acute care coordination for necessary social services for patients leaving the hospital after recovering from an episode of decompensated heart failure.
- Trial name
- NCT05388097
- Testing
- Managed Services
- Where
- 3 sites in United States
- Volunteers
- 320 people
- Sponsor
- Saint Luke's Health System
Heart Diseases
Use of Bedside Imaging and Community Health Workers for Early Screening and Referral of Pre-symptomatic Stage B Heart Failure in the Emergency Department
The goal of this clinical trial is to learn if using point-of-care ultrasound (POCUS) can increase participant engagement and changes in behavior among adults with risk factors for pre-symptomatic heart failure presenting to the…
- Trial name
- NCT06769880
- Testing
- Ultrasound and Educational Intervention, Educational Intervention Alone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
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