Clinical trials: Cardiac Health
Acute Coronary Syndrome, Prevention
Cholesterol Self-testing in Patients Post Acute Coronary Syndrome
The pharmacological reduction of LDL-C lowers cardiovascular risk and is therefore a priority in cardiovascular secondary prevention.
- Conditions
- Acute Coronary Syndrome, Prevention, LDL Hyperlipoproteinemia, Therapeutic Adherence
- Trial name
- C-Check (NCT06526013)
- Testing
- Cholesterol self-measurement
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Leipzig
Heart Failure, Cardiac Failure
Social Prescribing to Improve Adherence and Outcomes in Women With Heart Failure
Background: Heart Failure (HF) is the second most common cause of hospitalizations for women in North America. Non-adherence to guideline-directed medical therapy (GDMT) is associated with 50% of all treatment failures and high…
- Conditions
- Heart Failure, Cardiac Failure, Heart Decompensation, Congestive Heart Failure(CHF)
- Trial name
- NCT06628973
- Testing
- Social prescribing
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Preterm Birth, Pediatric Cancer
eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness
The overall aim is twofold: 1) to stretch the borderline regarding the present knowledge of clinical and economic cost-effectiveness of eHealth as an aid for facilitating and supporting self-management in families with long-term…
- Conditions
- Preterm Birth, Pediatric Cancer, Hirschsprung Disease, Congenital Malformation
- Trial name
- eChildHealth (NCT04150120)
- Testing
- e-health device with application, Mobile phone text messaging, early detection of cerebral palsy using a mobile phone application
- Where
- 7 sites in Denmark, Ethiopia and 1 more
- Volunteers
- 720 people
- Sponsor
- Lund University
Coronary Artery Disease, Smoking Cessation
PRISM-GENOMICS-Smoking Cessation for Patients With Coronary Artery Disease Undergoing Cardiac Catheterization or Having a Heart Attack at Barnes Hospital in St. Louis Mo
It has previously been shown that patients with coronary artery disease may have a harder time quitting smoking if they have a specific genetic profile and that these individuals have a better chance at quitting if they receive…
- Trial name
- NCT03383224
- Testing
- genotype-guided therapy, Nicotine patch, Smoking cessation counseling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Cardiovascular Diseases, Coronary Disease
Physicians' Health Study
To assess the effect on cardiovascular mortality of alternate-day consumption of 325 milligrams of aspirin and, secondarily, the effect on cancer incidence of alternate-day consumption of 50 milligrams of beta-carotene.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000500
- Testing
- aspirin, carotene
- Sponsor
- Brigham and Women's Hospital
Delivery of Health Care
Effect of Limicol on (LDL)-Cholesterol Levels in Moderate Hypercholesterolaemia
The purpose of this study is to validate the effectiveness of food supplement Limicol on reducing LDL-cholesterol in moderate hypercholesterolemic volunteers.
- Trial name
- NCT01139398
- Testing
- Limicol (plant extract)
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lescuyer Laboratory
Chylothorax
Chylothorax Following Heart Surgery
The purpose of this study is to determine at risk populations for certain congenital heart defects or certain operative procedures and to define the associated morbidity secondary to chylothorax - prolonged chest tube drainage…
- Trial name
- NCT00215098
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Children's Healthcare of Atlanta
Nutrition, Healthy
Standard Process Heart and Gut Health Study
Standard Process Heart and Gut Health Study
- Trial name
- NCT05795946
- Testing
- Whole food-based B and D vitamins
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Relieves Vaginal Dryness / Improves Self-Lubrication, Improves Strength & Elasticity of Vagina (Aka Collagen and Elastin)
A Clinical Trial to Evaluate the Effects of the NeuEve Dryness Treatment Kit on Vaginal Health, Comfort, and Quality of Life in Postmenopausal Women
This is a decentralized, single-group, open-label clinical trial evaluating a 12-week regimen of the NeuEve Dryness Treatment Kit (comprising Feminine Moisture Support oral softgels, Bone Support oral capsules, NeuEve Salve…
- Conditions
- Relieves Vaginal Dryness / Improves Self-Lubrication, Improves Strength & Elasticity of Vagina (Aka Collagen and Elastin), Improves Vaginal Wall Thickness, Reduces Pain During Sex
- Trial name
- NCT07893795
- Testing
- Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NeuEve
Heart Failure and Preserved Ejection Fraction, Obesity & Overweight
eHealth Lifestyle Intervention To Enhance Outcomes in HFpEF
The goal of this clinical trial is to learn if a digital lifestyle education program improves exercise capacity in adults who have heart failure with preserved ejection fraction (HFpEF) and overweight or obesity.
- Conditions
- Heart Failure and Preserved Ejection Fraction, Obesity & Overweight, Heart Failure
- Trial name
- ELITE-HFpEF (NCT07661732)
- Testing
- Digital lifestyle education program, Usual Care
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Cardiac Disease, Mental Health Issue
Exploring Potential Associations Between Rurality and Hopelessness in IHD Patients
Hopelessness is associated with 3.4 times increased risk of mortality or nonfatal myocardial infarction in patients with ischemic heart disease (IHD), independent of depression.
- Trial name
- NCT04498975
- Testing
- Rurality; Ethnicity; Exercise; Hopelessness
- Where
- 2 sites in United States
- Volunteers
- 125 people
- Sponsor
- Dordt University
HIV, Cardiovascular Disease
HealthMap: an Interactive Health Plan Randomised Trial to Prevent Cardiovascular Disease in People With HIV
The purpose of this study is to improve the health status of people living with HIV in Australia. The overall goal is to rigorously evaluate the impact of interactive health plans and self-management support on chronic condition…
- Trial name
- NCT02178930
- Testing
- Integrated self management support
- Where
- 14 sites in Australia
- Volunteers
- 731 people
- Sponsor
- Karen Klassen
Systemic Inflammatory Response Syndrome, Posttraumatic Stress Disorder
Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery
Hydrocortisone has been shown to improve the early outcome of high risk patients after cardiac surgery. A potential mechanism resulting in this effect may be its immunomodulatory action.
- Trial name
- NCT00490828
- Testing
- Hydrocortisone
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Acute Coronary Syndrome, Medication Adherence
Using Automated Calls To Improve Compliance With Acute Coronary Syndrome Best Practice Guidelines
The purpose of this study is to determine whether interactive voice response (IVR) technology can be used to bring post discharge care for acute coronary syndrome (ACS) closer to best practice guidelines (BPGs).
- Trial name
- NCT01151800
- Testing
- Using IVR to maintain ACS patients on best practice guidelines
- Where
- Canada
- Volunteers
- 1,608 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension
: Vascular Function in Health and Disease
Many control mechanisms exist which successfully match the supply of blood with the metabolic demand of various tissues under wide-ranging conditions.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
- Trial name
- NCT02966665
- Testing
- Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- D. Walter Wray
Congestive Heart Failure Chronic
Eat Well Heart Failure
The purpose of this parallel pragmatic randomized controlled trial (RCT) is to evaluate the impact of Eat Well (an evidence-based 'Food is Medicine' produce prescription program) with varying levels of behavioral support on…
- Trial name
- NCT07101289
- Testing
- Personal health planning and nutritional coaching, Prescription Produce
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Duke University
Heart Valve Diseases, Health Behavior
Study of Health Behavior in Patients After Heart Valve Replacement： Longitudinal Studies
To investigates the influencing factors and the pathways of health behavior in patients after heart valve replacement.
- Conditions
- Heart Valve Diseases, Health Behavior, Postoperative Period
- Trial name
- NCT06490952
- Where
- China
- Volunteers
- 219 people
- Sponsor
- Fujian Medical University Union Hospital
Diabetes, Heart Diseases
PREDICT 2: Personalized Responses to Dietary Composition Trial 2
Foods in the human diet can affect the development of diseases over time, such as diabetes or heart disease. This is because the amount and types of foods in the diet eat can affect a person's weight, and because different foods…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT03983733
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Hypertension, Type 2 Diabetes Mellitus
To Develop a High Quality Health Care Delivery Model for the Management of Hypertension and Diabetes at CHCs and District Hospitals of Himachal Pradesh.
Hypertension and diabetes are major risk factors for cardiovascular diseases. Although these two conditions can be detected much early in life and are amenable to interventions at primary health care level, the health system in…
- Trial name
- m-Power Heart (NCT01794052)
- Testing
- Evidence based, DSS enabled, health care delivery model
- Where
- India
- Volunteers
- 6,797 people
- Sponsor
- Centre for Chronic Disease Control, India
Heart Failure
VIrtual Care To Improve Outcomes and RecoverY From Heart Failure Hospitalization
The clinic visits (intervention) will continue for 90 days, which represents the follow-up period for the primary medication and health status outcomes. The co-primary clinical outcomes will be obtained at 180 days.
- Trial name
- VICTORY-HF (NCT05724433)
- Testing
- Virtual HF Care, Routine HF Care
- Where
- 9 sites in Canada, Tunisia
- Volunteers
- 891 people
- Sponsor
- Population Health Research Institute
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