Clinical trials: Cardiac Health
Heart Failure, Dilated Cardiomyopathy (DCM)
UIC Multi-Ethnic DCM Registry
Dilated cardiomyopathy (DCM), a condition where the heart loses its ability to pump blood throughout the body, is a common cause of death in the United States (US).
- Trial name
- NCT07145138
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Coronary Artery Disease
Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health
The goal of this clinical trial is to evaluate whether disclosure of a polygenic risk score for coronary artery disease (CAD PRS) influences cardiovascular health and risk factor modification over one year among adults aged 30-75…
- Trial name
- PROACT 3 (NCT07087431)
- Testing
- Immediate disclosure of CAD PRS results, Deferred Disclosure of CAD PRS results
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
Congenital Heart Disease (CHD)
Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)
This is a two-arm, prospective, longitudinal, randomized controlled trial (RCT) that will compare usual care to usual care plus a prenatally initiated, virtually administered psychological intervention, called HeartGPS.
- Trial name
- NCT07582861
- Testing
- HeartGPS
- Where
- 17 sites in United States
- Volunteers
- 210 people
- Sponsor
- Carelon Research
Congenital Heart Disease
Digital Health Nudging in Adolescents With Congenital Heart Disease
In adolescents with congenital heart disease physical activity level is reduced which is why promotion to a more active lifestyle with an age-appropriate and modern intervention is needed.
- Trial name
- NCT04933786
- Testing
- Digital Health Nudging
- Where
- Germany
- Volunteers
- 97 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Coronary Artery Disease, Cardiac Disease
Effects of Early Telerehabilitation in Coronary Artery Bypass Surgery Patients
The aim of this study was to investigate the effects of phase I and early phase II rehabilitation with telerehabilitation method and sleep hygiene training on physical capacity, cardiac functions, anxiety level, quality of life…
- Trial name
- NCT06240702
- Testing
- Telerehabilitation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Necmettin Erbakan University
Congenital Heart Disease
Enhanced Physical Activity Support in Congenital Heart Disease Clinical Care
Our cluster randomized controlled trial of a novel clinical practice change will IMPACT the physical activity (PA) of children living with congenital heart defects (CHD) through our Innovative and pragmatic approach to…
- Trial name
- PAToolKit (NCT03435354)
- Testing
- Physical activity counselling
- Where
- 3 sites in Canada
- Volunteers
- 155 people
- Sponsor
- Children's Hospital of Eastern Ontario
Chronic Heart Failure
Telemedical Interventional Monitoring in Heart Failure
Superiority of additional Remote Patient Monitoring in patients with CHF In comparison to usual care in terms of: reduction of mortality rate reduction of hospitalizations increasement of patients' quality of life
- Trial name
- TIM-HF (NCT00543881)
- Testing
- Remote patient monitoring (Partnership for the Heart), Usual care group
- Where
- 2 sites in Germany
- Volunteers
- 710 people
- Sponsor
- Charite University, Berlin, Germany
Aortic Valve Stenosis
Detection of Aortic Stenosis With Smartphone Auscultation Using Machine Learning (HEARTBEAT-Pilot)
Severe aortic stenosis, a common heart valve issue, is usually treated surgically or through intervention. Diagnosis typically occurs after symptoms appear, but research suggests already treating asymptomatic cases may help…
- Trial name
- NCT06404437
- Testing
- Auscultation
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Congestive Heart Failure
Congestive Heart Failure Pilot Study Utilizing Wireless Home Scale and Daily Symptom Monitoring
As the population ages and medicine advances, there has been a significant shift to the management of chronic diseases. Most chronic diseases are managed using evidence based consensus guidelines but clinician and patient…
- Trial name
- CHF (NCT03234088)
- Testing
- Daily weight measured by digital scale and symptom reporting
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pennsylvania
Acute Coronary Syndrome, Medication Adherence
Using IVR to Maintain ACS Patients on Best Practice Guidelines
The purpose of this study is to determine whether interactive voice response (IVR) technology can be used to bring post discharge care for acute coronary syndrome (ACS) closer to best practice guidelines (BPGs).
- Trial name
- IVR-ACS BPG (NCT01260207)
- Testing
- IVR group
- Where
- Canada
- Volunteers
- 654 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cardio-pulmonary
Cardiopulmonary Changes Prolonged Surgical Abdominal Retractors Application in Supine Versus Lateral Position
Introduction: Dynamic and static compliance should be calculated as a routine part of ventilator monitoring. Dynamic and static compliance are 60-100 mL/cm H2O.
- Trial name
- NCT03776292
- Testing
- monitoring
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Adherence, Patient, Motivation
Virtual Reality-enhanced Exercise and Education in Cardiac Rehabilitation
This study incorporates a virtual reality (VR) simulated walking environment, with audio component of patient education, into the treadmill portion of outpatient cardiac rehabilitation (CR).
- Conditions
- Adherence, Patient, Motivation, Satisfaction
- Trial name
- NCT03945201
- Testing
- Virtual walking trails, Standard of care
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Thomas Jefferson University
All Conditions Treated at the Heart Centres
DenHeart - Self-reported Health and Quality of Life at Hospital Discharge From a Heart Centre in Denmark
The objective of this study is to describe: 1) Differences in perceived health at hospital discharge between diagnostic groups and in-hospital predicting factors.
- Trial name
- DenHeart (NCT01926145)
- Where
- 5 sites in Denmark
- Volunteers
- 16,712 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Arthritis, Asthma
Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems
Behavioral problems are part of many of the chronic diseases that cause the majority of illness, disability and death. Tobacco, diet, physical inactivity, alcohol, drug abuse, failure to take treatment, sleep problems, anxiety…
- Conditions
- Arthritis, Asthma, Chronic Obstructive Lung Disease, Diabetes
- Trial name
- IBHPC (NCT02868983)
- Testing
- Integration
- Where
- United States
- Volunteers
- 4,025 people
- Sponsor
- University of Vermont
Cardiovascular Diseases
A Cardiac Registry to Evaluate and Manage the hsTnI Categorical CVD Risk in Subjects Undergoing Preventive Health Checks (PHC).
Cardiovascular disease is the leading cause of mortality globally. In India cardiovascular disease leads to death a decade earlier than in western countries.
- Trial name
- NCT04903041
- Where
- 6 sites in India
- Volunteers
- 300,000 people
- Sponsor
- Jaime Marino
Osteoarthritis
Balneotherapy and Echocardiographic Findings in Osteoarthritis
This prospective observational study aims to evaluate changes in heart function using echocardiography before and after a standardized balneotherapy program in adult and elderly patients with osteoarthritis.
- Trial name
- NCT06923969
- Testing
- balneotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Bursa City Hospital
Solid Organ Transplant, Heart Transplant
REmote moBile Outpatient mOnitoring in Transplant 2.0
This study is designed to determine if an innovative mobile health intervention designed to improve patient-provider communication can reduce unscheduled hospitalizations, and visits to the emergency department and ambulatory…
- Conditions
- Solid Organ Transplant, Heart Transplant, Liver Transplant, Kidney Transplant
- Trial name
- Reboot (NCT04721288)
- Testing
- Active communication through Reboot application, Generic communication through Reboot application
- Volunteers
- 400 people
- Sponsor
- University Health Network, Toronto
Coronary Artery Disease
Robotic-Assisted Percutaneous Coronary Intervention
Percutaneous coronary intervention is a safe procedure. However, its execution is manual, fully operator-dependent. The procedure is also associated with radiation exposure to patients and physicians.
- Trial name
- NCT03927560
- Testing
- Robotic Assisted Percutaneous Coronary Intervention
- Volunteers
- 83 people
- Sponsor
- Hospital Israelita Albert Einstein
Smoking Cessation
The Safety of Transdermal Nicotine Immediately Following an Acute Coronary Syndrome
Continuing to smoke after having a heart attack greatly increases the risk of death and cardiac illness. The nicotine patch is a commonly used pharmacotherapy for smoking cessation and has great potential to help heart attack…
- Trial name
- STADIA (NCT00990197)
- Testing
- Transdermal nicotine patch
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Cardiovascular Diseases, Heart Diseases
Modeling DNA Diversity in Cardiovascular Health/Disease
To identify and measure DNA sequence variation in 13 genes that play a central role in key physiological functions involved in the development of cardiovascular disease, that is, genes involved in lipid metabolism, carbohydrate…
- Trial name
- NCT00005490
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
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