Clinical trials: Cardiac Health
Heart Failure
Veterans Intensive Personalized Treatment in Heart Failure
In the VIP (Veterans Intensive Personalized) Treatment in Heart Failure Study we will assess 2 novel interventions to enhance adherence and improve quality of life in veterans with heart failure.
- Trial name
- VIP (NCT01404988)
- Testing
- Telephone-Delivered BI, Telephone-Delivered BEI, Telephone-Delivered API
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- US Department of Veterans Affairs
Delirium, Postoperative Delirium
Projection of Visual Material on Postoperative Delirium in Patients Undergoing Cardiac Surgery
The aim is to evaluate the impact of visual projection of images of relatives or loved ones in patients undergoing cardiac surgery in the immediate postoperative period, and its influence on the incidence and development of…
- Conditions
- Delirium, Postoperative Delirium, Cardiac Surgery
- Trial name
- VisualMaterial (NCT05932394)
- Testing
- Projection of Visual Material on Postoperative Delirium in Patients Undergoing Cardiac Surgery, the usual unit treatment
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- University of Huelva
Coronary Disease, Atherosclerosis
Health Coaching to Promote Physical Activity for Coronary Heart Disease Prevention
The purpose of this study is to evaluate the efficacy of motivational interviewing-based coaching to increase physical activity to achieve guidelines recommendations for cardiovascular disease prevention.
- Trial name
- NCT01089842
- Testing
- Health coaching, Usual care
- Where
- Spain
- Volunteers
- 262 people
- Sponsor
- Corporacion Parc Tauli
Coronary Heart Disease
Project 3: ACHIEVE- CHD
This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region) Center (IRB 100221MP2A), the purpose of which is to reduce cardiometabolic health…
- Trial name
- NCT05918380
- Testing
- PAL2, CINEMA
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University Hospitals Cleveland Medical Center
Adherence, Treatment, Coronary Artery Disease
Coronary Artery Disease and Exercise Adherence
This study aims to determine the factors affecting exercise adherence in patients with coronary artery disease (CAD). For this purpose, the following measurement tools will be used respectively: (1) "Patient Information Form"…
- Trial name
- NCT06364683
- Testing
- Survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Coronary Artery Disease, Non-significant Coronary Artery Disease
TweeSteden Mild Stenosis Study
Psychosocial factors have been found to be associated with an increased risk for coronary artery disease incidence, progression and worse clinical outcomes.
- Conditions
- Coronary Artery Disease, Non-significant Coronary Artery Disease, Mild Stenosis, Vascular Irregularities
- Trial name
- TWIST (NCT01788241)
- Where
- Netherlands
- Volunteers
- 547 people
- Sponsor
- Tilburg University
Anxiety, Heart Transplant Patients
Using Breathing Techniques to Ease Anxiety in ICU Patients Awaiting Heart Transplants
The goal of this clinical trial is to learn whether a breathing-based relaxation technique called heart rate variability biofeedback (HRVB) can help reduce anxiety in adult patients who are in the intensive care unit (ICU) and…
- Trial name
- NCT07381023
- Testing
- Heart Rate Variability Biofeedback (HRVB)
- Volunteers
- 60 people
- Sponsor
- Hartford HealthCare
Emotional Well-being, Psychological Stress
Feasibility of a Mind-Body Intervention for Optimism
This pilot study tests whether three brief mind-body activities can be delivered remotely to midlife adults, and whether they show early signs of improving cardiovascular health, emotional well-being, and stress.
- Conditions
- Emotional Well-being, Psychological Stress, Cardiovascular Risk
- Trial name
- NCT07862478
- Testing
- Emotional Well-Being Writing, Chair-Assisted Squats, Slow-Paced Breathing
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Penn State University
Exercise, Overreaching
Impact of Training Load on the Gut miCrobiome And Its Relation to exeRcise Performance, mUscle Phenotype, and markerS of Overreaching in Healthy Men
The goal of this study is to learn how different amounts of supervised indoor cycling training change gut health (gut bacteria, the substances gut bacteria make, and the gut barrier integrity), and how these changes relate to…
- Conditions
- Exercise, Overreaching, Butyrate, Gut Microbiome
- Trial name
- ICARUS (NCT07481578)
- Testing
- Supplement, Moderate load exercise training, High load exercise training
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Stefan De Smet
Hypertension (HTN), Blood Pressure
Team-Based Shared Decision-Making Program in Hypertension Control (Healthy Heart - BP Program)
The main goal of the study is to conduct a pilot trial to test the feasibility of the Team-Based Shared Decision-Making (SDM) Program, supported by Healthy Heart, involving 90 adults with uncontrolled hypertension (HTN) at…
- Trial name
- SDM in BP (NCT07909161)
- Testing
- Pharmacist-led Team-Based SDM on health behavior change and medication management for HTN control, Nurse-led Team-Based SDM on health behavior change and medication management for HTN control, Telehealth SDM visits focus on medication management and health behavior change
- Volunteers
- 90 people
- Sponsor
- Johns Hopkins University
Pregnancy-Associated Hypertension, Gestational Hypertension
Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure
High blood pressure during or after pregnancy (such as preeclampsia, gestational hypertension, eclampsia, or Hemolysis, Elevated Liver enzymes, and Low Platelet (HELLP) syndrome) raises a mother's risk of heart disease later in…
- Conditions
- Pregnancy-Associated Hypertension, Gestational Hypertension, Preeclampsia, Eclampsia
- Trial name
- AW2H (NCT07778966)
- Testing
- Alabama Womb to Heart Solution (AW2H) Community Health Worker (CHW) Program, Usual postpartum care with self-measured blood pressure education and home blood pressure monitor
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- University of Alabama at Birmingham
Heart Failure
Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)
Background: More than 6.5 million people in the United States live with heart failure (HF), and more than a million new cases are diagnosed each year.
- Trial name
- NCT06280820
- Where
- 2 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Heart Defect, Heart Defects, Congenital
Fetal Cardiac Anomalies at Anomaly Scan: Detection and Pregnancy Outcomes - Assiut 2026
Congenital heart defects are among the most common congenital anomalies and cause significant perinatal morbidity and mortality. Prenatal detection allows counseling, multidisciplinary planning and optimization of delivery.
- Trial name
- NCT07832851
- Volunteers
- 200 people
- Sponsor
- Assiut University
Cancer, Stress, Psychological
Brief Mindfulness Chatbot Intervention for Cancer Patients
This study tests a new digital tool for hospitalized cancer patients. The tool is a chatbot on LINE, a popular messaging app. The chatbot is called Mindbot. Mindbot leads a 10-minute mindfulness practice each day.
- Trial name
- MINDBOT-CA (NCT07811739)
- Testing
- Mindbot: Brief Mindfulness-Based LINE Chatbot with Virtual Reality
- Volunteers
- 66 people
- Sponsor
- Taipei Medical University
Acute Coronary Syndrome, Smoking Cessation
Early In-hospital Initiation of Pharmacotherapy for Smoking Cessation, Patients After ACS
The hypothesis of this study is that combination of Varenicline treatment with nurse-led hospital support during hospitalization and after discharge will result in clinically significant higher long term abstinence rates in…
- Trial name
- NCT02106637
- Testing
- Varenicline
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Cardiovascular Diseases
Response of Cardiometabolic Biomarkers and Gut Microbiota to Walnut Consumption
The purpose of this research is to test if eating walnuts will cause any changes in blood lipids (like good and bad cholesterol, for example) and levels of inflammation in the blood, as well as changes in the bacteria living in…
- Trial name
- NCT05321277
- Testing
- Walnuts, No-nut diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Transition, Diabetes
Healthcare Transition of Adolescents With Chronic Health Conditions
At least 12% of children have a chronic disease that requires regular medical follow-up after patients reach legal maturity. This international study aims to provide prospective evidence for improving health and wellbeing…
- Conditions
- Transition, Diabetes, Kidney Diseases, Liver Diseases
- Trial name
- NCT04631965
- Testing
- Transition support service
- Where
- 2 sites in Australia, Finland
- Volunteers
- 503 people
- Sponsor
- University of Helsinki
Heart Defects, Congenital, Parenting
Tuning in to Kids: An Online, Group Program Tailored for Parents of Children With Congenital Heart Disease
The goal of this clinical trial is to learn if a virtually-delivered, group-based psychological intervention, called Tuning in to Kids, is feasible and acceptable for parents of children aged 3 to 6 years with congenital heart…
- Conditions
- Heart Defects, Congenital, Parenting, Emotion Regulation
- Trial name
- NCT06609707
- Testing
- Tuning in to Kids
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Diabetes, Hypertension
Exploring Folk Health Practices in Latinos With Chronic Medical Conditions
This study will explore how culture influences the use of folk healing practices and medical services in Latinos with chronic medical conditions.
- Conditions
- Diabetes, Hypertension, Asthma, Heart Disease
- Trial name
- NCT00224237
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Weill Medical College of Cornell University
Telerehabilitation, Cardiac Rehabilitation
Hospital-to-Home Transitional Cardiac Rehabilitation After Cardiac Surgery
Cardiac rehabilitation (CR) improves outcomes after cardiac surgery, but is usually delivered on a fixed centre-based schedule that requires repeated daytime hospital attendance.
- Conditions
- Telerehabilitation, Cardiac Rehabilitation, Cardiac Surgical Procedures, Heart Valve Diseases
- Trial name
- NCT07811102
- Testing
- Hybrid cardiac rehabilitation, Centre-based cardiac rehabilitation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Cheng-Hsin General Hospital
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