Clinical trials: Cardiac Health
Health Behavior
Grenada Heart Project - Community Health Action to Encourage Healthy Behaviors
The Grenada Heart Project (GHP) conducted an observational study within a randomly selected adult sample of Grenadians in 2008-2009.
- Trial name
- GHP CHANGE (NCT02428920)
- Testing
- Peer Groups
- Where
- Grenada
- Volunteers
- 400 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiovascular Risk Reduction of Having a Coronary Event
A Novel Approach to Cardiovascular Health by Optimizing Risk Management (ANCHOR)
Study Purpose and Design The goal of this study is to improve CVD risk in a primary care adult population, with the following primary objectives 1.
- Trial name
- ANCHOR (NCT01620996)
- Testing
- Minimal Intervention, Motivational Interviewing, Motivational Enhancement
- Where
- Canada
- Volunteers
- 1,708 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Marfan Syndrome
Marfan Syndrome Moderate Exercise Trial II
Marfan syndrome (MFS) is a distinctive connective tissue disorder that affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection.
- Trial name
- NCT05809323
- Testing
- Exercise Intervention Group, Control Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Smoking Cessation, Coronary Artery Disease
Cytisine Compared to Combination NRT in Relapsed Smokers
Cigarette smoking causes cardiovascular disease (CVD) yet many smokers with CVD are unable to quit despite strong desire to do so.
- Trial name
- CYTvsNRT+ (NCT04286295)
- Testing
- Cytisine, Nicoderm C-Q Transdermal Product, Nicorette Lozenge Product
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Preeclampsia, Hypertensive Disorder of Pregnancy
Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
This is a single site, single-blinded parallel randomized control trial that investigates a multi-level intervention to improve postpartum blood pressure in women with hypertensive disorder pregnancy.
- Conditions
- Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications
- Trial name
- HHD (NCT05655936)
- Testing
- Heart Health Doula Intervention Program, Usual Care
- Where
- United States
- Volunteers
- 454 people
- Sponsor
- University of Pittsburgh
Cerebrovascular Accident, Transient Ischemic Attack
The Post Stroke Preventive Trial (PREVENT). A RCT Nested in a Cohort Study
Patients with a diagnosis of stroke or TIA, who are already included in the RIALTO-cohort study are asked to participate in a RCT after discharge from hospital.
- Conditions
- Cerebrovascular Accident, Transient Ischemic Attack, Myocardial Infarction
- Trial name
- PREVENT (NCT00253097)
- Testing
- Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 353 people
- Sponsor
- Hvidovre University Hospital
Sepsis, Asthma
Evaluation of Essential Surgical Skills-Emergency Maternal and Child Health Training
The aim of the proposed study is to determine if specific training in management of general, obstetric, neonatal and pediatric emergencies results in a change in practice of doctors working in emergency departments of public…
- Conditions
- Sepsis, Asthma, Heart Failure, Seizure
- Trial name
- NCT00880204
- Testing
- ESS-EMCH training
- Where
- 2 sites in Pakistan
- Volunteers
- 36 people
- Sponsor
- Child Advocacy International
Troponin, Age
NIHR CV Health Informatics Collaborative
The National Institute for Health Research (NIHR) Cardiovascular Health Informatics Collaborative is an observational, multi-centre and longitudinal study of clinical data from collaborating hospitals.
- Conditions
- Troponin, Age, Mortality, Acute Coronary Syndrome
- Trial name
- NHIC-CV (NCT03507309)
- Volunteers
- 257,948 people
- Sponsor
- Imperial College London
Heart Failure
Efficacy of the PEAC-IC: a Randomized Controlled Clinical Trial
A randomized parallel single-center clinical trial, blinded for the evaluation of the outcomes and statistical analysis. The current hypothesis is that PEAC-IC will improve self-care behavior, knowledge about heart failure…
- Trial name
- PEAC-IC (NCT05081414)
- Testing
- Program for Teaching Self-Care in HF (PEAC-IC)
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo
Acute Myocardial Infarction, Chronic Heart Failure
Pilot Study of ILIADE : Exploring Health Literacy Within Patients Hospitalized for Acute Cardiovascular Events
Health literacy (HL) is the ability to access, understand, evaluate and apply information in order to communicate with health professionals and understand health instructions but also, promote, maintain and improve health…
- Trial name
- P-ILIADE (NCT03949309)
- Testing
- Exploring health literacy levels and patients' informal needs or individual relationship between caregivers and patients.
- Where
- France
- Volunteers
- 209 people
- Sponsor
- Hospices Civils de Lyon
Cardiovascular Diseases
Comparing Multicomponent and Isometric Multicomponent Training: Impact on Fitness, Health, and Life Quality in Heart Patients
The goal of this clinical trial is to evaluate if a multicomponent training program (MCT), including aerobic and resistance exercises, or an isometric multicomponent training program (IMCT) can improve physiological, physical…
- Trial name
- NCT06819098
- Testing
- Multicomponent Training Protocol, Isometric Multicomponent Training
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Bari Aldo Moro
Atrial Fibrillation, Anticoagulants
Use of Public Health Surveillance Models in the French National Health System Database
Public health surveillance models, previously used for the ongoing detection of occurrence of rare events, could be used to reinforce existing pharmacovigilance systems.
- Conditions
- Atrial Fibrillation, Anticoagulants, Pharmacoepidemiology
- Trial name
- DABI-SURV (NCT02904499)
- Testing
- Dabigatran
- Where
- France
- Volunteers
- 814,446 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Sleep Problems, Depressive Disorder and Anxiety Disorders
The Impact of Melatonin Lotion on Sleep and Mental Health
The purpose of this study is to examine the effect that melatonin lotion has on sleep quality, the nervous system, and mental health.
- Trial name
- NCT06768749
- Testing
- Melatonin lotion
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Redlands
Patient Acceptance of Health Care, Nursing
Mobile Education and Telephone Monitoring for ICD Patients: Effects on Anxiety, Acceptance, and Self-Efficacy
Aim: This study was conducted to determine the effect of a mobile education program and telephone monitoring developed for patients with implantable cardioverter defibrillators (ICD) on shock anxiety, device acceptance, and…
- Conditions
- Patient Acceptance of Health Care, Nursing, Implantable Cardioverter Defibrillator (ICD), Self-Efficacy
- Trial name
- NCT06935526
- Testing
- The mobile training program and telephone follow-ups, Only a two-page summary section of M-ICDEP
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Akdeniz University
Cardiac Rehabilitation, Secondary Prevention
Effectiveness of the Aktivplan Digital Intervention (ACTIVE-CaRe Pilot)
The goal of this clinical pilot / feasibility study is to determine the feasibility of conducting a large-scale clinical effectiveness trial of the aktivplan digital intervention in cardiac rehabilitation patients.
- Conditions
- Cardiac Rehabilitation, Secondary Prevention, Cardiovascular Diseases
- Trial name
- NCT06025526
- Testing
- aktivplan, Usual care
- Where
- 2 sites in Austria
- Volunteers
- 34 people
- Sponsor
- Ludwig Boltzmann Institute for Digital Health and Prevention
Acute Coronary Syndromes, Depression
Integrating Depression Care in Acute Coronary Syndromes Care in China
The overall goal of this study is to develop, pilot test, implement, and evaluate a nurse-coordinated depression care model integrated into the care of Acute Coronary Syndromes (ACS) patients with rigorous assessment of…
- Trial name
- I-Care (NCT02195193)
- Testing
- Integrated care
- Where
- China
- Volunteers
- 4,043 people
- Sponsor
- The George Institute for Global Health, China
Overweight and/or Obesity
Body-Based and Mind-Based Regulation in Overweight and Obese Women
This study will compare two regulation-based approaches in women with overweight or obesity. The first approach is a body-based regulation program including breathing awareness, body-awareness-based yoga practices, non-invasive…
- Trial name
- NCT07738263
- Testing
- Body-Based Regulation Program, Mind-Based Regulation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Atrial Fibrillation
Optimal Antiplatelet Therapy Following Left Atrial Appendage Closure
SAFE-LAAC Trial has been designed to gather data on the most optimal strategy of antiplatelet therapy after transcatheter left atrial appendage occlusion with Amplatzer or WATCHMAN device
- Trial name
- SAFE-LAAC (NCT03445949)
- Testing
- short postimplantation dual antiplatelet therapy, extended postimplantation dual antiplatelet therapy, long-term treatment with a single antiplatelet agent
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Cardiac Rehabilitation, Physical Activity
Evaluation of an E-intervention on MHBC for Chinese Cardiac Patients in Home-based Rehabilitation
By using the Health Action Process Approach (HAPA) model as a theoretical backdrop, the proposed study aims to provide a 10-week e-health learning strategies for Chinese cardiac patients, with which they can follow at home after…
- Conditions
- Cardiac Rehabilitation, Physical Activity, Fruit and Vegetable Intake
- Trial name
- NCT03636724
- Testing
- E-intervention
- Where
- China
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Psychological Stress, Cardiopulmonary Bypass Surgery
CARINAE for Stress Relief in Perioperative Care
Preventing pre-surgical stress can help patients achieve positive outcomes on health and well-being. However, very few patients receive adequate stress relief support prior to a surgical procedure.
- Conditions
- Psychological Stress, Cardiopulmonary Bypass Surgery, Coronary Artery Bypass Surgery, Cardiac Valve Replacement
- Trial name
- CARINAE (NCT05184725)
- Testing
- SaMD CARINAE
- Where
- 5 sites in Italy, Netherlands and 1 more
- Volunteers
- 50 people
- Sponsor
- Adhera Health, Inc.
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