Clinical trials: Cardiac Health
Coronary Artery Disease, Myocardial Infarction
Impact of a Corrie Cardiac Rehabilitation Program
In this randomized clinical trial, the researchers are investigating whether a multi-component virtual/hybrid cardiac rehabilitation program will improve functional status, cholesterol level, overall cardiovascular health…
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Myocardial Ischemia, Coronary Artery Occlusion
- Trial name
- mTECH-Rehab (NCT05238103)
- Testing
- Corrie Hybrid Cardiac Rehabilitation Program
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- Johns Hopkins University
Oral Health, Dental Caries
Improved Oral Health and Dental Care in Children with Congenital Heart Disease
Background: Congenital heart disease (CHD) is one of the most common congenital anomalies in children. As the risk for endocarditis following bacteraemia is more common during daily oral hygiene routines, such as tooth brushing…
- Trial name
- ORALPEDHEART (NCT03329170)
- Testing
- educational intervention using motivational interviewing
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- My Blomqvist
Atrial Fibrillation
The Comparative Safety and Effectiveness of Dabigatran, Versus Rivaroxaban, and Apixaban Utilized in the Department of Defense Non-Valvular Atrial Fibrillation Patient Population: A Retrospective Database Analysis
The purpose of this study is to assess the safety and effectiveness of newly initiated dabigatran among patients diagnosed with non valvular atrial fibrillation (NVAF) in comparison to newly initiated rivaroxaban users and newly…
- Trial name
- NCT03026556
- Testing
- Dabigatran vs. Rivaroxaban, Dabigatran vs. Apixaban
- Where
- United States
- Volunteers
- 42,534 people
- Sponsor
- Boehringer Ingelheim
Heart Failure, Arrhythmias, Cardiac
Evaluation of ECG Transmission and AI Models Using Apple Watch ECGs and Symptoms Data Collected Using a Mayo iPhone App
The purpose of the study is to determine if the Electrocardiograms (ECGs) and symptoms data obtained from an Apple Watch and transmitted to Mayo Clinic are of sufficient quality to guide a person's care.
- Conditions
- Heart Failure, Arrhythmias, Cardiac, Health Care Utilization
- Trial name
- NCT05324566
- Where
- United States
- Volunteers
- 4,163 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hypertrophic Cardiomyopathy
A Study to Assess Health-Related Quality of Life in Patients With Hypertrophic Cardiomyopathy in Japan
This cross-sectional, non-interventional study will assess health-related quality of life in in patients with hypertrophic cardiomyopathy in Japan. The study consists of two phases.
- Trial name
- NCT06181617
- Testing
- Quality of life assessment
- Where
- Japan
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Hypertension
Food Is Medicine: Makin' Healthy Groceries
This is a minimal risk study focusing on food purchasing and consumption in 100 subjects in the greater New Orleans area. There is evidence showing that individually-targeted vouchers effectively increase category-level food…
- Trial name
- FIM (NCT06214806)
- Testing
- Grocery Vouchers
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Duke University
Worksite Health Promotion, Lifestyle Risk Reduction
Worksite Wellness Within Long-term Care Facilities
The goal of this proposed study is to test the feasibility and preliminary efficacy of worksite wellness program designed to reduce worker stress (job and personal) and improve cardiovascular disease among long-term care workers.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Cardiovascular Diseases, Occupational Stress
- Trial name
- NCT04166643
- Testing
- WHHIP PLUS, Education only control
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Myocardial Infarction
The Box: Using Smart Technology to Improve One-year Outcome of Myocardial Infarction Patients
Study to investigate whether a smart technology intervention can improve clinical and cost-effectiveness of one-year follow-up in patients who suffered from acute myocardial infarction.
- Trial name
- TheBox (NCT02976376)
- Testing
- The Box
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Leiden University Medical Center
Patient Satisfaction, Dehydration
NPO and Patient Satisfaction in the Cath Lab
The purpose of this randomized, control study is to compare liberal vs strict nil per os (NPO) policies on patients undergoing transcatheter aortic valve replacement (TAVR) or arrhythmia ablation.
- Conditions
- Patient Satisfaction, Dehydration, Physiological Effects Secondary to Dehydration
- Trial name
- FAST (NCT04079543)
- Testing
- NPO past midnight, NPO
- Volunteers
- 200 people
- Sponsor
- Stony Brook University
Coronary Heart Disease
ESCAP: Supervised Exercise for Patients With Coronary Heart Disease in the Primary Care Setting
In Spain, family physician are currently recommended to prescribe an unsupervised walking program to their coronary heart disease (CHD) patients as a part of their cardiac rehabilitation program.
- Trial name
- NCT00146315
- Testing
- Supervised exercise on a stationary bicycle, 3-5 days a week, Secondary prevention program for coronary heart disease
- Where
- 2 sites in Spain
- Volunteers
- 97 people
- Sponsor
- Basque Health Service
Heart Health Markers, General Nutritional Status
Effects of Supplementation in Healthy Russian Population
The objectives of this exploratory study are to (1) evaluate the effect of the multivitamin multimineral with phytonutrient product vs.
- Trial name
- NCT02224092
- Testing
- multivitamin multimineral with phytonutrient supplementation
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Asthma, Allergy
GeoHealth: Geographic Information System for Health Management and Clinical, Epidemiological and Translational Research
The objective of the project is to develop a potentially marketable system for clinical, epidemiological and translational research capable of associating contextual variables and geospatial data with clinical patient…
- Conditions
- Asthma, Allergy, Heart Diseases, Obesity
- Trial name
- NCT05637411
- Testing
- Predictive model
- Where
- Spain
- Volunteers
- 214 people
- Sponsor
- Hospital Universitario Virgen Macarena
Dementia, Dementia Alzheimers
Acrylamide and Health Outcomes
Acrylamide, a widespread food-processing contaminant, poses a major public health concern due to its high exposure level in the general population and its toxicity.
- Conditions
- Dementia, Dementia Alzheimers, Parkinson Disease, Myocardial Infarction
- Trial name
- NCT06224725
- Testing
- dietary acrylamide exposure measured via biomarkers in blood (hemoglobin adducts of acrylamide and glycidamide)
- Where
- Sweden
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Inflammation, Cardiovascular Diseases
Inflammation in Acute Cardiovascular Diseases - the CArdiovascular Inflammation Registry (CAIR)
Following acute cardiovascular injury, inflammation is vital to activate reparative mechanisms. However, there is compelling evidence implicating excessive inflammation and dysregulated resolution in fibrosis, ventricular…
- Conditions
- Inflammation, Cardiovascular Diseases, Myocarditis, Pericarditis
- Trial name
- CAIR (NCT06411340)
- Testing
- Observation
- Volunteers
- 1,000 people
- Sponsor
- King's College London
Cardiovascular Disease, Coronary Disease
Effects of Cardiac Rehabilitation (CR) on Functional Capacity and Cardiovascular Risk Factors
The purpose of this trial are to pragmatically investigate whether participation in a comprehensive CR (i.e., exercise with education) program in a Latin American MIC results in better functional capacity, cardiovascular risk…
- Trial name
- NCT02575976
- Testing
- comprehensive CR, exercise-based CR, wait list control
- Where
- Brazil
- Volunteers
- 115 people
- Sponsor
- Federal University of Minas Gerais
Heart Failure
Patient Activation in High-Risk Patients With Heart Failure
The purpose of this study was to determine the efficacy of a self-management program, called the Heart PACT Program, compared to usual health care in patients with heart failure.
- Trial name
- HeartPACT (NCT00260650)
- Testing
- Heart PACT Program
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- VA Office of Research and Development
Atrial Fibrillation (AF)
Detection of Atrial Fibrillation Using PPG From Smartphone Cameras
The protocol is designed to enroll patients from at least 3 diverse clinical sites with smartphones who are being evaluated for the presence or absence of atrial fibrillation (AF) using the Heart Rhythm Software algorithm running…
- Trial name
- FLASH AF (NCT07779213)
- Testing
- 12 Lead ECG is compared to a smartphone based PPG
- Where
- 5 sites in United States, Netherlands
- Volunteers
- 554 people
- Sponsor
- Happitech BV
Anticoagulants, Atrial Fibrillation
Improving Anticoagulation Control in VISN 1
Over 100,000 VHA patients receive anticoagulants (blood thinners) each year to prevent blood clots (including strokes). Too much anticoagulation increases the risk of serious or even fatal bleeding, and too little anticoagulation…
- Conditions
- Anticoagulants, Atrial Fibrillation, Venous Thromboembolism
- Trial name
- NCT01653405
- Testing
- Multifaceted behavioral intervention
- Where
- United States
- Volunteers
- 1,260,576 people
- Sponsor
- VA Office of Research and Development
Atrial Fibrillation (AF)
Testing the Performance of Smartphones and Their Accessories in Detecting Irregularly Irregular Heart Rhythm
The purpose of this 4-in-1 observational study is to test the performance of artificial intelligences (AIs) in distinguishing irregularly irregular heart rhythm called atrial fibrillation (AF) from normal heart rhythm using…
- Trial name
- NCT07154303
- Testing
- Computer algorithms
- Where
- China
- Volunteers
- 209 people
- Sponsor
- The University of Hong Kong
Type 2 Diabetes (T2DM)
Implementing WHO HEARTS-D Guidelines in Bangladesh for Diabetes Control and Prevention
Type-2 diabetes (T2D) is rising at an alarming rate in the low- and middle-income countries (LMIC). This rapid increase in the T2D burden has a particular impact on cities, where more than half the LMIC populations currently live…
- Trial name
- T2D IR (NCT07155902)
- Testing
- The community-to-facility integrated strategy
- Volunteers
- 5,000 people
- Sponsor
- Florida International University
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