Clinical trials: Cardiac Health
Coronary Artery Disease, Cardiac Catheterization
Benefits of no Fasting Compared to Fasting Prior to Elective Cardiac Catheterization: A Single-center Randomized-controlled Trial
More than one million cardiac catheterizations (CCs) are performed annually in the United States and the majority are elective. Current guidelines recommend no fasting prior to elective CC, however recent studies suggest that…
- Conditions
- Coronary Artery Disease, Cardiac Catheterization, Cardiac Diseases
- Trial name
- FAST CATH (NCT07150780)
- Testing
- Pre-operative instructions to eat and drink at liberty
- Volunteers
- 2,000 people
- Sponsor
- Munson Medical Center
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches in Ouagadougou, Burkina Faso
Ambient air temperatures in Africa, have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06842641)
- Testing
- Cool roof
- Where
- Burkina Faso
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Institut Supérieur des Sciences de la Population
Cardiovascular Diseases, Coronary Disease
National Health and Nutrition Examination Survey IV (NHANES (IV)
To supplement the fourth National Health and Nutrition Examination Survey protocol to include data on the common heart, vascular, lung, and blood diseases.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Hypertension
- Trial name
- NCT00005154
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Myocardial Infarction, Acute
Cardiac Rehabilitation With Motivational Interview for Acute Myocardial Infarction
Introduction: Secondary prevention after acute myocardial infarction may include cardiac rehabilitation and lifestyle changes. Cardiac rehabilitation has mainly taken place in hospitals without coordination with primary…
- Trial name
- NCT05285969
- Testing
- Motivational interview, Active Comparator: Standard care group
- Where
- 4 sites in Spain
- Volunteers
- 284 people
- Sponsor
- Consorci d'Atenció Primària de Salut de l'Eixample
Adult Disease
Relationship of the Physical Activity Practice and Its Different Domains With Cardiac Autonomic Modulation
Overall objective: To analyze the relationship of the physical activity practice measured directly with the autonomic cardiac modulation in adults.
- Trial name
- NCT03986879
- Where
- Brazil
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Bruna Thamyres Ciccotti Saraiva
PTSD, Cardiac Arrest
Stellate Ganglion Blockade to Reduce Cardiac Anxiety and PTSD Symptoms in Cardiac Arrest Survivors
This is a pilot randomized controlled trial (RCT) to gain preliminary evidence regarding the acceptability, tolerability, safety, and efficacy of a combined intervention of Stellate Ganglion Blockade (SGB) and psychoeducation on…
- Conditions
- PTSD, Cardiac Arrest, Anxiety and Fear, Sleep Disturbance
- Trial name
- SGB-PsychoED (NCT04582396)
- Testing
- stellate ganglion block injection, Normal saline injection, Psychoeducation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Columbia University
Blood Sugar; High, Overweight and Obesity
Effect of a Glucagon Like Peptide 1 (GLP1) Booster in Healthy Humans
BACKGROUND GLP1 booster (GB) was designed to stimulate the endogenous production of GLP1, which in turn releases insulin, controls blood glucose level, suppresses appetite and thus helps people lose weight.
- Conditions
- Blood Sugar; High, Overweight and Obesity, Fat Burn, Obesity
- Trial name
- NCT06333496
- Testing
- GLP-1 Booster (GB)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alpine Biotech LLC
Type 2 Diabetes Mellitus, Acute Coronary Syndrome
Telephone Intervention in Patients With Acute Coronary Syndrome (ACS) and Diabetes
Hypothesis To investigate whether telephone counselling by nurse educator between clinic visits with particular emphasis on adherence to medications and lifestyle modification in patients with coronary heart disease and diabetes…
- Trial name
- NCT00816010
- Testing
- telephone contact
- Where
- Hong Kong
- Volunteers
- 137 people
- Sponsor
- Chinese University of Hong Kong
Angina
Ranolazine Among Unrevascularized Chronic Stable Angina Patients
This is a prospective, double-blind, placebo-controlled, randomized, single-center (North Florida- South Georgia VA Medical Center) study.
- Trial name
- IMWELL (NCT02265796)
- Testing
- Ranolazine, Sugar pill
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- North Florida Foundation for Research and Education
Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, Brca2)
Genetics and Heart Health After Cancer Therapy
The overall objective of this study is to use patient-centered in vitro and in vivo models to answer the fundamental question of whether or not pathogenic mutations in BRCA1/2 result in an increased risk of CV disease
- Conditions
- Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, Brca2), Heart Diseases, Drug-Induced Cardiomyopathy
- Trial name
- Gene-HEART (NCT03510689)
- Testing
- echocardiography, Cardiopulmonary Exercise Testing, Blood Collection
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Heart Disease
Heart & Health Study
We hope to learn more about why certain people have higher levels of the 5-LO protein and whether taking fish oil supplements gives such individuals greater protection than others against cardiovascular disease.
- Trial name
- NCT00536185
- Testing
- Fish Oil
- Where
- 3 sites in United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Heart Failure
The Effect of Education Given to Patients With Heart Failure on Self-care, Drug Compliance and Quality of Life.
This study was planned as a randomized, controlled, experimental study to evaluate the effects of transtheoretic model-based education on self-care, drug compliance and quality of life in patients with heart failure.
- Trial name
- NCT05418478
- Testing
- Intervention transtheoretical model group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Harran University
Congenital Heart Disease, Psychological Well-being
The Living Experience of Hong Kong Chinese Adolescents With CHD.
This study aims to explore the impacts of CHD and its limitations on adolescents and the living experience of adolescents living with CHD.
- Conditions
- Congenital Heart Disease, Psychological Well-being, Quality of Life, Adolescent
- Trial name
- NCT03677232
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
Left Ventricular Remodeling, Medication Adherence
IMproving reModeling in Acute myoCardial Infarction Using Live and Asynchronous TElemedicine.
The proposed research aims to compare Left ventricular remodeling outcomes among patients with AMI and elevated NT-pro-B-type natriuretic peptide receiving telemedicine-guided post-MI treatment vs.
- Conditions
- Left Ventricular Remodeling, Medication Adherence, Acute Coronary Syndrome
- Trial name
- IMMACULATE (NCT02468349)
- Testing
- Telemedicine
- Where
- 3 sites in Singapore
- Volunteers
- 300 people
- Sponsor
- National University Heart Centre, Singapore
Coronary Artery Disease
Group-based Cardiac Telerehabilitation and Its Effectiveness
Cardiovascular diseases (CVD) and coronary artery diseases (CAD) are the most common cause of death worldwide. After an acute cardiac event, prevention of new cardiac events is essential and reduces suffering.
- Trial name
- NCT05923580
- Testing
- Group- based cardiac telerehabilitation
- Where
- Finland
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Smartphone Users, Smartphone Addiction, Anxiety, and Skin Conductance
The Relationship Among Electroencephalography,Skin Conductance Response,Heart Rate Variability and Mental Health Among Smartphone Users After Receiving Texting or Calling
The number of smartphone users in Taiwan continues to increase exponentially. Smartphone addiction tends to not only disrupt the ability of social communication but cause physical and psychological problems as well.
- Trial name
- NCT04133597
- Testing
- social media stimuli (Line app)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Heart Failure, Reduced Ejection Fraction
Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.
The purpose of this study was to investigate the effects of initiation of sacubitril/valsartan vs enalapril treatment on objective measures of both waking activity and sleep in subjects with heart failure with reduced ejection…
- Trial name
- AWAKE-HF (NCT02970669)
- Testing
- sacubitril/valsartan (LCZ696), enalapril
- Where
- 23 sites in United States
- Volunteers
- 140 people
- Sponsor
- Novartis Pharmaceuticals
Heart Disease, Mental Health Outcomes
The Feasibility of an Intervention Targeting Sources of Meaning in Cardiac Rehabilitation
Being diagnosed with heart disease can be a life-changing experience, often sparking existential questions and concerns about meaning in life.
- Conditions
- Heart Disease, Mental Health Outcomes, Rehabilitation
- Trial name
- NCT07262580
- Testing
- Conversation on Sources of Meaning in life with heart disease, Group based session on Sources of Meaning in life with heart disease, Dyadic Conversation on Sources of Meaning in Life with heart disease
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Trisomy 21, Trisomy 18
Prenatal Screening for Down Syndrome With DNAFirst
This study will explore how maternal plasma circulating cell free DNA (ccfDNA) can be used as a primary screening test for Down syndrome as part of routine clinical care in the general pregnancy population.
- Conditions
- Trisomy 21, Trisomy 18, Trisomy 13, Monosomy X
- Trial name
- DNAFirst (NCT01966991)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Coronary Artery Disease
Impact of Health Literacy on Outcomes and Effectiveness of Shared Decision Making Programs in Patients With Chronic Diseases
Study objective was to explore the impact of health literacy on effectiveness of an educational intervention describing life-style and behavior modification for patients "Living with Coronary Artery Disease." Our hypothesis was…
- Trial name
- NCT01083862
- Testing
- Educational Intervention - Text plus DVD/VHS, Educational Intervention - Text Only
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- University of Cincinnati
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