Clinical trials: Cardiac Health
COPD, Heart Failure
Personalized Experiences to Inform Improved Communication for Minorities With Life Limiting Illness
The purpose of this research is to develop patient-centered palliative care interventions to improve patient-provider communication and Quality of Life (QoL) of ethnic and racial minority patients living with life-limiting…
- Conditions
- COPD, Heart Failure, Cancer
- Trial name
- NCT03391115
- Testing
- Storytelling Intervention for Patient Participants, Storytelling Intervention for Nurse Participants
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hypertension (HTN)
Hypertension Treatment in Nigeria 2.0
The purpose of the second phase of the Hypertension Treatment in Nigeria (HTN 2.0) Program is to build upon the success of the first phase of the HTN Program (2020-2023), which implemented the WHO HEARTS package across 60 primary…
- Trial name
- HTN 2 (NCT07351162)
- Testing
- Implementation of a modified WHO HEARTS Hypertension Treatment Bundle
- Where
- 49 sites in Nigeria
- Volunteers
- 10,000 people
- Sponsor
- Washington University School of Medicine
Pregnancy
Acute Effects of High Intensity Training in Pregnancy on Fetal Well-being and Blood Flow Distribution
Pregnant women are recommended to be physically active ≥150 min/week, but <15% of Norwegian women attain this goal. Several well-designed studies on lifestyle interventions focusing primarily on exercise training in…
- Trial name
- HITFLOW (NCT04288479)
- Testing
- Single high-intensity interval training session
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Norwegian University of Science and Technology
Mental Health Wellness 1, Stress, Psychological
Heartfulness Meditation to Improve Resilience Among Health Care Students: A 90 Day Program
This investigation will examine the feasibility of delivery and effect on resilience, depression and anxiety of a 90-day Heartfulness Practice delivered virtually for health care students.
- Conditions
- Mental Health Wellness 1, Stress, Psychological, Depression, Anxiety
- Trial name
- HEART (NCT04790162)
- Testing
- Heartfulness Meditation
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Atrial Fibrillation, Familial Atrial Fibrillation
Atrial Fibrillation Health Literacy and Information Technology Trial in Rural Pennsylvania Counties
Atrial fibrillation (AF) is a highly prevalent, morbid condition. Anticoagulation to prevent thromboembolic strokes is a foremost priority in AF but adherence is challenging for patients and lapses in anticoagulation are common.
- Conditions
- Atrial Fibrillation, Familial Atrial Fibrillation, Arrhythmia, Cardiac, Heart Diseases
- Trial name
- AFibLITT_R (NCT04076020)
- Testing
- Relational agent/AliveCor Kardia - Intervention, Usual Care
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Pittsburgh
Heart Failure, Congestive
Personal Decision Support System for Heart Failure Management
Despite the availability of evidence-based guidelines for disease management in patients with congestive heart failure (CHF), the uptake of these guidelines in clinical practice is sub-optimal and adherence rates are…
- Trial name
- HeartMan (NCT03497871)
- Testing
- HeartMan system
- Where
- 4 sites in Belgium, Italy
- Volunteers
- 79 people
- Sponsor
- Jozef Stefan Institute
Psychological Stress, Heart Rate Variability
A Database for Emotion Analysis Using Physiological and Psychological Assessment by 40FY
A comprehensive study examining the physiological, emotional and psychological aspects of stress among Korean adults
- Conditions
- Psychological Stress, Heart Rate Variability, Mental Health Services
- Trial name
- NCT06172673
- Where
- South Korea
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- 40FY
Stroke, Not Specified as Hemorrhage or Infarction, Angina Pectoris
Clinical Study of Medicinal Product Cardionat® Using in Health Athlete Volunteers
The objective of this study is to evaluate the long-term plasma and urine pharmacokinetic parameters of Cardionat®, capsules 250 mg, when used in healthy athlete volunteers. The study consists of four steps: Step 1.
- Trial name
- NCT02758912
- Testing
- оral intake of study drug capsules; study drug - Cardionat ® (trimethylhydrazinium propionate dihydrate), oral capsules 250 mg
- Where
- Russia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Chronic Heart Failure
Interactive Patient's Assistant - LUCY
Patients with chronic heart failure (CHF) and reduced left ventricle ejection fraction benefit from cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillator (ICD).
- Trial name
- NCT03474315
- Testing
- Multivariate assessment
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- Medical University of Warsaw
Frailty, Cardiovascular Diseases
MultiMorbidity Life-Course Approach To Myocardial Health -A Cardiac Sub-Study of the MRC National Survey of Health and Development (NSHD)
Background The life course accumulation of overt and subclinical myocardial dysfunction contributes to older age mortality, frailty, disability and loss of independence.
- Trial name
- MyoFit46 (NCT05455125)
- Testing
- CMR CGI
- Where
- United Kingdom
- Volunteers
- 550 people
- Sponsor
- University College, London
Advanced Heart Failure, Mechanical Circulatory Support
Palliative Care Intervention to Improve Health Related Quality of Life for Patients on Long-Term LVAD Support
Background: While left ventricular assist device (LVAD) therapy improves survival in patients with advanced heart failure (AHF), unique LVAD-related burdens may impact health-related quality of life (HRQoL).
- Conditions
- Advanced Heart Failure, Mechanical Circulatory Support, Left Ventricular Assist Device, Palliative Care
- Trial name
- PALL-VAD (NCT07445932)
- Testing
- Palliative care intervention
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Medstar Health Research Institute
Heart Failure, Frailty
INTEgRated Health CARE for Patients With Frailty and Heart Failure
Frailty, an aging-related syndrome of physiological decline characterized by marked vulnerability to adverse health outcomes, has attracted increasing attention in cardiology due to the growing elderly population with heart…
- Conditions
- Heart Failure, Frailty, Frail Elderly Syndrome, Symptom, Behavioral
- Trial name
- INTERCARE-HF (NCT06444321)
- Testing
- INTERCARE-HF
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Vestre Viken Hospital Trust
Cardiovascular Diseases, Diabetes Mellitus
Nurses' Health Study (Cardiovascular Component)
To determine the relationships of hormonal, reproductive, dietary, and lifestyle factors, as well as biochemical and genetic factors, with the subsequent risk of coronary heart disease and other cardiovascular events in a cohort…
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Coronary Disease, Heart Diseases
- Trial name
- NCT00005152
- Volunteers
- 121,700 people
- Sponsor
- Brigham and Women's Hospital
Diabetes, Heart Diseases
Personalized Responses to Dietary Composition Trial 3
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT04735835
- Testing
- Dietary Intervention
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Heart Failure
Verizon Wireless - Sarasota Memorial Hospital Converged Health Management (CHM) For Heart Failure
The primary objective is to evaluate the impact on heart failure related quality of life when integrating a mobile health system, Verizon Wireless's Converged Health Management (CHM), into a subject's self-management of their…
- Trial name
- NCT01829152
- Testing
- CHM
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Verizon Wireless
Heart Disease, Stroke
Using Virtual Counselors to Overcome Genetic Literacy Barriers
A Relational Agent (RA) "virtual counselor" (VICKY: VIrtual Counselor for Knowing Your Family History) has been developed to collect family health history information for common health conditions including heart disease, stroke…
- Conditions
- Heart Disease, Stroke, Diabetes, Cancer
- Trial name
- VICKY (NCT02344433)
- Testing
- VICKY, MFHP
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Boston University
Cardiovascular Risk Factors
Community Approaches to Cardiovascular Health: Pathways to Heart Health
The Specific Aims for CATCH: PATH are: Specific Aim 1: To promote cardiovascular health through implementation and evaluation of a multilevel CBPR intervention (i.e., individual, family, organizational levels) to increase…
- Trial name
- CATCH-PATH (NCT02036593)
- Testing
- Walk Your Heart to Health
- Where
- United States
- Volunteers
- 695 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction
A Trial on the Role of Community Pharmacist in Improving Adherence and Clinical Outcomes in Post-Infarction
The purpose of this pilot study is to evaluate the effectiveness of the active involvement of Community Pharmacists in improving adherence to medical prescriptions in patients with acute myocardial infarction (AMI), reducing the…
- Conditions
- Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction (nSTEMI)
- Trial name
- IM-ADHERENCE (NCT03621111)
- Testing
- Patient-counseling, Patient self-administered questionnaire, Pills counts
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda ULSS 5 Polesana
Myocardial Infarction
Examination of the Impact of CalmiGo's Stress Management Device on Vascular Heath and Cardiovascular Disease Risk.
The primary purpose of this study is to determine if there are significant differences with respect to baseline between those randomized to CGo and standard-of-care versus standard-of-care alone after completing 12-weeks of…
- Trial name
- CalmiGo (NCT04521699)
- Testing
- CalmioGO Stress management device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
The Focus is to Investigate Effects of a Disease Management Intervention for Patients With Congestive Heart Failure
A Disease Management Study Targeted to Reduce Health Care Utilization for Patients With Congestive Heart Failure
The aim of this study is to determine whether a nurse-managed telephone-based disease-management intervention can reduce healthcare utilization and improve self-assessed health status in patients with congestive heart failure.
- Trial name
- NCT02251899
- Testing
- Disease-Management intervention
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Health Navigator
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