Clinical trials: Cardiac Magnetic Resonance
Heart Failure, Myocardial Infarct
Observational Study of the Remodelling Process Following Myocardial Infarct
This study will assess the relationship between collagen turnover, neurohormonal activation, scarring and left ventricle remodelling in patients 3 years following a myocardial infarction.
- Trial name
- NCT00338156
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- Helse Stavanger HF
Heart Failure, Systolic
Effects of CRT Optimization as Assessed by Cardiac MR
Cardiac resynchronization therapy (CRT), or atrial-synchronized biventricular (BiV) pacing, is an FDA-approved device therapy option for heart failure (HF) patients with reduced left ventricular ejection fraction and electrical…
- Trial name
- NCT04763460
- Testing
- Programming of CRT device settings
- Where
- 2 sites in United States
- Sponsor
- Minneapolis Heart Institute Foundation
ST Segment Elevated Myocardial Infarction
Early rhBNP on Myocardial Remodeling and Reperfusion in Patients With STEMI
The study intends to evaluate the efficacy of early rhBNP on myocardial remodeling and reperfusion in patients with ST-segment elevation myocardial infarction after percutaneous coronary intervention
- Trial name
- NCT04033861
- Testing
- rhBNP, Control
- Where
- China
- Volunteers
- 352 people
- Sponsor
- RenJi Hospital
Cardiac Arrythmias
Sparsity-based Magnetic Resonance Imaging of Cardiac Arrhythmias
The primary purpose of this study is to improve the quality of Magnetic Resonance Imaging in patients with heart arrhythmia. Investigators will recruit 105 patients with arrhythmia and 30 control volunteers over 3 years and will…
- Trial name
- NCT02741180
- Testing
- 3D Imaging, Late Gadolinium Enhancement (LGE)
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Coronary Artery Disease, Carotid Artery Diseases
Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)
Heart attacks and strokes caused by the unstable atherosclerotic plaques remain the leading cause of death in the United States. Unstable plaques often have more fat than stable plaques.
- Conditions
- Coronary Artery Disease, Carotid Artery Diseases, Atherosclerosis
- Trial name
- NCT01178320
- Testing
- Simvastatin, simvastatin plus extended-release niacin
- Where
- 19 sites in United States, Canada
- Volunteers
- 230 people
- Sponsor
- University of Washington
Coronary Artery Disease, Type 1 Diabetes Mellitus
Regadenoson Blood Flow in Type 1 Diabetes (RABIT1D)
Cardiovascular disease (CVD) remains the major cause of mortality and morbidity in both type 1 (T1D) and type 2 (T2D) diabetes patients; modifications of traditional CVD risk factors have had a limited impact.
- Trial name
- RABIT1D (NCT01019486)
- Testing
- Regadenoson myocardial perfusion imaging, Regadenoson MRI myocardial blood flow
- Where
- 4 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Tachyarrhythmia
Magnetic Resonance (MR) Conditional Tachyarrhythmia Therapy Products Post-approval Study
Following product approval, further confirmation of the MR Conditional Tachyarrhythmia Therapy Systems sensing and detection performance post MRI exposure will be obtained by actively monitoring de-identified device data obtained…
- Trial name
- NCT02849769
- Testing
- Implant of an MR-conditional Tachy device system
- Volunteers
- 10,979 people
- Sponsor
- Medtronic
Arrhythmogenic Cardiomyopathies
Tissue and Metabolic Characterization of Arrhythmogenic Cardiomyopathies by Hybrid PET-MRI Imaging, Impact of the Observed Profiles on the Phenotype and on the Evolution of Cardiomyopathy
Status of the research project: The main complications of arrhythmogenic cardiomyopathies (AC) are sudden death, more rarely heart failure.
- Trial name
- CharACTPET-MR (NCT05450783)
- Testing
- Biocollection
- Where
- 5 sites in France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital
Heart Transplant Rejection
Research on Patients With Heart Transplantation
This trial was a single-center, prospective cohort study.The purpose of this clinical research is to evaluate the accuracy of combining multimodality MR Imaging with circulating exosomal miRNA expression to diagnose acute…
- Trial name
- NCT04921774
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangdong Provincial People's Hospital
Hypertension, Pulmonary
A Study for the Identification of Biomarker Signatures for Diagnosis of Pulmonary Hypertension (PH) in Participants at Low or Intermediate Probability of PH Undergoing Cardiac Magnetic Resonance Imaging
The primary purpose of this study is to estimate the percentage of participants in the population considered clinically as not having pulmonary hypertension (PH) that are positive for PH biomarker (micro ribonucleic acid [RNA])…
- Trial name
- NCT04480723
- Testing
- Blood Sample, Cardiac MRI
- Where
- 8 sites in Germany, United Kingdom
- Volunteers
- 86 people
- Sponsor
- Actelion
NAFLD, Heart Failure
T1-mapping by Cardiovascular Magnetic Resonance Imaging to Assess Non-Alcoholic Fatty Liver Disease
On clinically indicated Cardiovascular Magnetic Resonance studies, native T1-times and extracellular volume of the liver will be assessed and findings correlated with established risk calculators for non-alcoholic fatty liver…
- Conditions
- NAFLD, Heart Failure, Valvular Disease, Coronary Disease
- Trial name
- NCT04220450
- Testing
- T1 mapping on Cardiovascular Magnetic Resonance Studies
- Where
- Austria
- Volunteers
- 800 people
- Sponsor
- Dr. Andreas Kammerlander
Cardiomyopathy, Dilated, Prognosis
Cardiac Magnetic Resonance-Clinical Prediction Model-Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is a common and serious heart disease characterized by left ventricular enlargement and impaired pumping function, with adverse prognosis (including heart failure, arrhythmia, heart-related…
- Conditions
- Cardiomyopathy, Dilated, Prognosis, Magnetic Resonance Imaging, Cardiac, Death, Sudden, Cardiac
- Trial name
- MPS-CMR-DCM (NCT07527715)
- Testing
- left ventricular ejection fraction
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Heart Failure, Diastolic, Multicenter Study
Diagnosis and OutcoMes evaluAtIoN of Multicenter Patients With HFpEF Using Multimodality Imaging
The incidence of Heart failure with preserved ejection fraction (HFpEF) in Heart failure patients increases rapidly. However, the current clinical awareness is insufficient, and the cardiac structural and functional injury are…
- Trial name
- NCT04602338
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Aortic Surgery
Changes in Elastic Properties of Descending Thoracic Aorta After Ascending Aorta Replacement
The aim of our study was to evaluate the impact of aortic root replacement by a graft on the elastic properties of the descending thoracic aorta using cardiac Magnetic Resonance Imaging (MRI) and automatic post-processing.
- Trial name
- NCT03817008
- Testing
- Ascending aorta replacement with graft
- Volunteers
- 19 people
- Sponsor
- Centre Hospitalier La Chartreuse
Children, Heart Diseases
Study to Evaluate the Optimal Dose of Remifentanil During MRI of the Heart Under General Anaesthesia
What is the optimal maintenance dose of remifentanil to ensure apnoea, during breath hold episodes in children having cardiac MR imaging with general anaesthesia?
- Conditions
- Children, Heart Diseases, Anaesthesia, Magnetic Resonance Imaging
- Trial name
- NCT02481791
- Testing
- Remifentanil and/or propofol, propofol
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Myocardial Infarction
Safety and Efficacy of SeeMore (TM) in Heart Patients
This study will examine the safety and effectiveness of a manganese-based agent called SeeMore (EVP 1001-1 Injection) for enhancing magnetic resonance imaging (MRI) in patients who have previously had a heart attack.
- Trial name
- NCT00881075
- Testing
- SeeMore(TM)
- Volunteers
- 24 people
- Sponsor
- Eagle Vision Pharmaceutical Corp.
Asthma, Pulmonary Disease, Chronic Obstructive
Right Heart Dysfunction and Pulmonary Hypertension Evaluation in Airway Disease Using Cardiac Magnetic Resonance
Poor function of the right side of the heart and rise in pressure of the blood vessels leading to the lungs are two main heart-related factors that are associated with worsening of airway disease.
- Trial name
- RiPAIR (NCT02865577)
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Patent Foramen Ovale
Patent Foramen Ovale (PFO) and Risk of Perioperative Stroke
This is a multi-centre, prospective cohort study to determine if asymptomatic PFO is a risk factor for developing perioperative overt and covert stroke in patients undergoing non-cardiac surgery.
- Trial name
- CAPPRES (NCT05592301)
- Testing
- Diffusion-weighted Magnetic Resonance Imaging (DW-MRI), Transcranial Doppler (TCD), Transthoracic Echocardiogram (TTE)
- Where
- Canada
- Volunteers
- 408 people
- Sponsor
- University Health Network, Toronto
Dilated Cardiomyopathy
Dilated Cardiomyopathy-Cardiac Magnetic Resonance (DCM-CMR) Ancillary Study
The Dilated Cardiomyopathy-Cardiac Magnetic Resonance (DCM-CMR) Study is an ancillary study from the parent study, DCM Precision Medicine Study.
- Trial name
- NCT04638621
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Giant Cell Arteritis (GCA)
Cardiac Involvement in Patients With Giant Cell Arteritis
This prospective observational study aims to investigate whether patients with newly diagnosed giant cell arteritis (GCA) show signs of cardiac involvement.
- Trial name
- NCT07031284
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- University Hospital, Bonn