Clinical trials: Cardiac Magnetic Resonance
Myocardial Ischemia, Left Ventricular Systolic Dysfunction
The Acute Cardiovascular Effects of Marathon Running Using Magnetic Resonance Imaging
Using blood testing and cardiac magnetic resonance imaging (MRI), the investigators aim to determine if there are necrotic areas of myocardium in participants who complete a marathon.
- Conditions
- Myocardial Ischemia, Left Ventricular Systolic Dysfunction, Elevated Cardiac Enzymes
- Trial name
- MARATHON-MRI (NCT00752752)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Magnetic Resonance Imaging, Cardiac Magnetic Resonance Imaging
Evaluation of a Free-breathing Cardiac Cine-MRI Sequence With Image Reconstructions by Deep-Learning in Ischemic Heart Disease
Today, MRI is the gold standard for the precise assessment of left ventricular volume and function, but presents the drawback of having a long acquisition time and of generating motion artifacts, in particular respiratory…
- Conditions
- Magnetic Resonance Imaging, Cardiac Magnetic Resonance Imaging, Deep-Learning, Left Ventricular Ejection Fraction
- Trial name
- CINEDL (NCT05105984)
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Transplant Failure, Heart Transplant Rejection
MuLtimodality EvaluatiOn of aNtibody mEdiated Damage in Heart Transplantation (LEONE-HT)
Cross-sectional evaluation of antibody mediated injury in heart transplantation patients through a multimodal approach: electron microscopy, optic microscopy, immunohistochemistry techniques, transthoracic echocardiography…
- Conditions
- Transplant Failure, Heart Transplant Rejection, Antibody-mediated Rejection
- Trial name
- LEONE-HT (NCT05184426)
- Testing
- Echocardiogram, Cardiac magnetic resonance, Coronary angiography
- Where
- 3 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Juan Francisco Delgado Jimenez
Acute Myocardial Infarction
Revascularization Strategies for STEMI; The CMR Endpoint Study
Revascularization strategies for ST elevation myocardial infarction (STEMI) study (ASSIST-CMR) will compare the effects of two revascularization strategies [same sitting multivessel primary PCI (SS-PCI) and culprit vessel only…
- Trial name
- ASSIST-CMR (NCT01818960)
- Testing
- IRA-PCI, SS-PCI
- Where
- 3 sites in Canada
- Volunteers
- 250 people
- Sponsor
- Unity Health Toronto
Coronary Artery Stenosis
iNav-based, Automated Coronary Magnetic Resonance Angiography for the Detection of Coronary Artery Stenosis
Ischaemic Heart Disease (IHD) is the worlds leading cause of death. IHD is often caused by a narrowing of the coronary arteries, which prevents blood from flowing to the heart muscle, causing pain and damage to the heart.
- Trial name
- iNav-AUTO CMRA (NCT05473117)
- Testing
- Coronary Magnetic Resonance Angiography (CMRA)
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Aarhus University Hospital
Right Ventricular Hypertrophy, d-TGA
Right Ventricular Hypertrophy After Atrial Switch and Cardiovascular Magnetic Resonance (CMR) Findings
Systemic RV hypertrophy and impaired systolic function occur after atrial switch (AS) in d-transposition of the great arteries (d-TGA). Echocardiography has limitation in the assessment of the right ventricle (RV).
- Trial name
- NCT01430897
- Where
- Germany
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Paroxysmal Atrial Fibrillation
EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation
Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).
- Trial name
- EXCLAMATORY (NCT06212791)
- Testing
- Self- Report Evaluation-Duke Activity Status Index, Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire, Cardiopulmonary exercise test (CPET)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Virginia Commonwealth University
Cardiac Disease
Validation of Combined PET-MR Quantitative Parameters for Cardiac Applications
The purpose of this study is to understand how simultaneous PET/MR acquisition can provide novel qualitative and quantitative biomarkers to guide clinical intervention and predict prognosis of patients with cardiovascular disease.
- Trial name
- NCT02062008
- Testing
- PET-MRI
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Chest Pain, Severe Aortic Stenosis
Myocardial Flow Reserve in Severe AS Without Obstructive Coronary Artery Disease
Exertional angina is common symptom in patients with severe aortic stenosis (AS) without obstructive coronary artery disease (CAD).
- Trial name
- NCT02575768
- Testing
- Adenosine-stress cardiac magnetic resonance imaging
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Ischemic Heart Disease
Correlation Between Left Ventricular Global Strain Measured by Speckle Tracking Echocardiography and Scar Burden Measured by Cardiac Magnetic Resonance Imaging in Patients With Ischemic Heart Disease
To verify whether GLS and LV mechanical dispersion, measured by two-dimensional speckle-tracking echocardiography (2D-STE) correlate with LV scar burden measured by cardiac MRI in patients with ischemic heart disease.
- Trial name
- NCT04970017
- Testing
- Cardiac MRI, Echocardiography
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Assiut University
Heart Failure, Diastolic
Multimodality Imaging in the Screening, Diagnosis and Risk StratifictiON of HFpEF
The incidence of Heart failure with preserved ejection fraction (HFpEF) in Heart failure patients increases rapidly. However, the current clinical awareness is insufficient, and the cardiac structural and functional injury are…
- Trial name
- NCT04603404
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Ischemic Heart Disease (IHD), Myocardial Infarction (MI)
CMR Prognostic Markers in Ischemic Heart Disease
Ischemic heart disease (IHD) remains a leading cause of morbidity and mortality worldwide. Accurate risk stratification is essential for guiding clinical management and improving long-term outcomes in patients with ischemic…
- Trial name
- NCT07351825
- Testing
- Cardiac Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Non-valvular Atrial Fibrillation (AF)
Watchman FLX Pro CT Pilot Study
The primary objective of this study is to measure device tissue coverage post-implantation of the WATCHMAN FLX™ Pro Left Atrial Appendage Closure (LAAC) Device (WATCHMAN FLX Pro) using the serial advanced imaging modalities of…
- Trial name
- NCT05567172
- Testing
- Left atrial appendage closure device WM FLX Pro
- Where
- Denmark
- Volunteers
- 43 people
- Sponsor
- Boston Scientific Corporation
Cardiac Function, Sedation
Effect of Midazolam and Dexmedetomidine on Heart Function - A Randomized MRI-based Study.
To compare the changes in heart function, induced after sedation with midazolam or dexmedetomidine, using cardiac magnetic resonance imaging (MRI).
- Conditions
- Cardiac Function, Sedation, Magnetic Resonance Imaging
- Trial name
- MRI (NCT04529187)
- Testing
- Midazolam, Dexmedetomidine
- Where
- Czechia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Masaryk Hospital Krajská zdravotní a.s.
Myocardial Ischemia, Myocardial Infarction
Magnetic Resonance Technique in the Assessment of Exercise-induced Long- and Short-Term Changes in Cardiac Function and Morphology
Until now it has been assumed that regular endurance training has a positive influence on cardiac function and that the positive effect increases with increasing intensity.
- Conditions
- Myocardial Ischemia, Myocardial Infarction, Ventricular Remodeling, Myocardial Contraction
- Trial name
- NCT01305304
- Testing
- repeated long term endurance exercise, Other
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Magnetic Resonance Imaging (MRI), Cardiac Pacing
Evaluation of Approved Pacing Lead (Model 5076) for Use in MRI Environment
The purpose of this study is to test the safety and effectiveness of the Medtronic CapSureFix Novus Model 5076 lead when patients are implanted with the Medtronic Advisa MRI pacemaker and undergo an MRI scan.
- Trial name
- NCT01755143
- Testing
- Magnetic Resonance Imaging scan sequences of the head, neck, and chest, Pacemaker System
- Where
- 36 sites in Australia, Austria and 17 more
- Volunteers
- 266 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Heart Failure With Reduced Ejection Fraction (HFrEF), Chronic Heart Failure
Vericiguat and Reverse Remodeling Indices in Heart Failure
The goal of this clinical trial is to investigate how vericiguat benefits adults with stable heart failure with reduced ejection fraction (HFrEF) who are already receiving guideline-directed medical therapy.
- Trial name
- VERI-PATH (NCT07405944)
- Testing
- Vericiguat, Guideline Directed Medical Therapy for Heart Failure (GDMT)
- Where
- 4 sites in Slovenia
- Volunteers
- 70 people
- Sponsor
- University Medical Centre Ljubljana
Atrial Fibrillation
Study of the Effect of Cardioversion on Cardiac Volume in Patients With Persistent Atrial Fibrillation
The main objectives in this study were to examine the cardiac structural and functional changes in patients with persistent and permanent AF, with the aim of improving our understanding of the underlying pathophysiological…
- Trial name
- NCT00209911
- Testing
- cardioversion
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Coronary Artery Plaque Components
Magnetic Resonance Imaging (MRI) Analysis of Coronary Artery Plaque Components
The purpose of this study is to analyze atherosclerotic vessel wall components with multidetector computed tomography (MDCT) and compare with MRI.
- Trial name
- NCT00559728
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Cardiac Toxicity, Chemotherapeutic Agent Toxicity
Cardiac Magnetic Resonance Imaging in Patients With Non-Hodgkin Lymphoma or Hodgkin Lymphoma Receiving Doxorubicin
RATIONALE: Diagnostic procedures, such as cardiac magnetic resonance imaging, may help doctors detect early changes in the heart caused by chemotherapy.
- Conditions
- Cardiac Toxicity, Chemotherapeutic Agent Toxicity, Lymphoma
- Trial name
- NCT00577798
- Testing
- contrast-enhanced magnetic resonance imaging
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska