Clinical trials: Cardiac Magnetic Resonance
Myocardial Infarction
Post Conditioning in PCI for Acute ST Elevation Myocardial Infarction
The purpose of this trial is to compare post-conditioning to standard angioplasty (50/50 chance) in patients who present with an acute heart attack and are taken directly for an angioplasty procedure.
- Trial name
- NCT00334373
- Testing
- Post conditioning
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- University of Calgary
Healthy, Dilated Cardiomyopathy
Molecular and Imaging Studies of Cardiovascular Health and Disease
Biobank is a program which collects biological samples, health information and imaging data from consented patients and stored them at the core facility.
- Conditions
- Healthy, Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy, Ischemic Heart Disease
- Trial name
- Biobank (NCT02804269)
- Testing
- Cardiovascular Magnetic Resonance, Fatmass measurement
- Where
- Singapore
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Mechanical Dyssynchrony, Heart Failure
Evaluating Effects of a Left Bundle Branch Block
A left bundle branch block (LBBB) is related to abnormal cardiac conduction and mechanical asynchrony and is associated with hypertension and coronary artery disease.
- Conditions
- Mechanical Dyssynchrony, Heart Failure, Bundle-Branch Block
- Trial name
- NCT00269659
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Cardiac Sarcoidosis
PET/MR Imaging In Patients With Cardiac Sarcoidosis
PET scanning (positron emission tomography) is a well-established technique used to identify areas of interest within the body. It involves injecting a radioactive tracer which highlights abnormal areas.
- Trial name
- NCT03705884
- Testing
- 18F-FDG, Prednisolone
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Chagas Disease, Colchicine Resistance
Colchicine for Patients With Chagas´ Disease( B1 Stage)
This study evaluate the addition of colchicine in the treatment of patients with Chagas´disease. Forty patients will receive colchicine while twenty patients will receive placebo
- Trial name
- COACH (NCT03704181)
- Testing
- Colchicine 0.5 MG twice day for one year
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Magnetic Resonance Imaging, Tetralogy of Fallot
4D Velocity Mapping of the Heart in rTOF Patients
MRI with 4D flow permits to assess the hemodynamic parameters in a parent vessel and its branches inside the same sequence.
- Trial name
- CARDIOFLUX (NCT02980614)
- Testing
- 4D flow imaging
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cardiovascular Diseases, Heart Diseases
Plaque Inflammation and Dysfunctional HDL in AIM-HIGH
Coronary heart disease (CHD) is a serious health concern that affects millions of people in the United States. It is usually caused by atherosclerosis-a condition that occurs when fatty material and plaque build up on the walls…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Atherosclerosis
- Trial name
- HDL Proteomics (NCT00880178)
- Testing
- Simvastatin and Extended-Release niacin, Simvastatin
- Where
- 29 sites in United States, Canada
- Volunteers
- 324 people
- Sponsor
- University of Washington
Pulmonary Vein Stenosis
Calculating Wall Shear Stress in Infant Pulmonary Veins
The purpose of this study is to better understand pediatric pulmonary vein stenosis (PVS), which is the narrowing of blood vessels that connect the lungs to the heart. PVS is a life-threatening disease without a clear cause.
- Trial name
- PVS-WSS (NCT06440408)
- Testing
- Ferumoxytol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Coronary Disease
Evaluate the Effectiveness and Cost of Stress Cardiac Magnetic Resonance Imaging (MRI) for Non-invasive Evaluation of Lesions Discovered on Computed Tomography Angiography (CCTA)
This study is designed to evaluate the effectiveness and measurable cost impact of stress cardiac MRI for non-invasive evaluation of intermediate lesions discovered on CCTA in low-to-intermediate risk patients admitted to the ED…
- Trial name
- DSTAT (NCT00538460)
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Duchenne Muscular Dystrophy
Natural History of Duchenne Muscular Dystrophy Cardiomyopathy (DMD-CMP)
The purpose of this study is to describe the progression of tissular and functional myocardial abnormalities in patients with Duchenne muscular dystrophy using cardiac magnetic resonance imaging and blood biomarkers assays.
- Trial name
- DMD-CMP (NCT05558813)
- Testing
- Cardiac MRI, Blood assays
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ST-Elevation Myocardial Infarction
Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome
In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury.
- Trial name
- NCT00952224
- Testing
- magnetic resonance imaging
- Where
- Germany
- Volunteers
- 267 people
- Sponsor
- University of Leipzig
Myocardial Infarction
CCT for Comprehensive Risk Stratification Following STEMI
The CT-STEMI study aims to evaluate a comprehensive cardiac computed tomography (CCT) protocol for assessing the risk of heart failure (HF), life-threatening arrhythmias (LTA), and atherothrombotic events following ST-elevation…
- Trial name
- CT-STEMI (NCT06020209)
- Testing
- Cardiac Computed Tomography, Cardiac Magnetic Resonance
- Where
- 3 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Turin, Italy
ST Elevation (STEMI) Myocardial Infarction
Impact of Persistent Microvascular Obstruction by Cardiac Magnetic Resonance on Prognosis for ST-segment Elevation Myocardial Infarction
The aims of the study were to evaluate the predictive value of persistent microvascular obstruction (MVO) by cardiac magnetic resonance for main adverse cardiac events in ST-segment elevation myocardial infarction patients.
- Trial name
- IMCOME (NCT06759532)
- Where
- China
- Volunteers
- 344 people
- Sponsor
- Chinese PLA General Hospital
Heart Failure With Reduced Ejection Fraction
The ENVI Study: Effect of Entresto on Left Ventricular Remodelling on Cardiac MRI
A prospective, single centre, observational cohort study at University Hospital Southampton NHS Foundation Trust of 50 consecutive patients with Heart Failure with reduced Ejection Fraction and Ejection Fraction ≤35% who are…
- Trial name
- ENVI (NCT05348226)
- Testing
- Additional Cardiac Magnetic Resonance Scan
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Myocardial Infarction, Heart Failure
Sodium Thiosulfate to Preserve Cardiac Function in STEMI
Rationale: Timely and effective reperfusion by primary percutaneous coronary intervention (PPCI) is currently the most effective treatment of ST-segment elevation myocardial infarction (STEMI).
- Trial name
- GIPS-IV (NCT02899364)
- Testing
- Sodium thiosulfate, Sodium chloride 0.9%, primary percutaneous coronary intervention
- Where
- 3 sites in Netherlands
- Volunteers
- 380 people
- Sponsor
- University Medical Center Groningen
Cardiac Failure
The Development and Optimization of a Cardiac Magnetic Resonance Imaging Protocol in a 3 Tesla Scanner
In recent years, evaluating cardiac function with magnetic resonance imaging (MRI) has drawn widespread interest. However, cardiac MRI is prone to severe motion artifacts from cardiac contraction, frequently requiring complex…
- Trial name
- NCT07889076
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Wang . Jiun-Jie
Stroke, Ischemic, Inflammation
MR Evidence of Cardiac Inflammation Post-Stroke
The present study is an investigator initiated, single-centre, prospective, proof-of-concept cohort study aiming to enroll 44 patients with acute middle cerebral artery (MCA) ischemic stroke, involving the right (n=22) and left…
- Conditions
- Stroke, Ischemic, Inflammation, Myocardial Injury
- Trial name
- MIRACLE (NCT05714618)
- Testing
- Gadolinium-enhanced cardiac MRI, B Natriuretic Peptide, Systemic inflammatory markers
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Luciano A. Sposato
Heart Failure With Preserved Ejection Fraction (HFPEF)
Mangafodipir - an Intracellular Contrast Agent for Magnetic Resonance Imaging (MRI): Measuring Manganese Uptake Rate in Heart Failure Patients With Preserved Ejection Fraction (HFpEF) Patients.
More than half of heart failure patients have preserved ejection fraction (HFpEF), a condition caused by increased wall stiffness that impairs proper heart filling.
- Trial name
- NCT06731738
- Testing
- Gadoteric acid, Mangafodipir trisodium injection
- Where
- Norway
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- IC TARGETS AS
Pulmonary Hypertension
Diagnosis of Pulmonary Hypertension Using Cardiac Magnetic Resonance Images
In this study, study team aim to i) evaluate the accuracy of 3D IVS curvedness for prediction of RV systolic pressure (RVSP), mean pulmonary artery pressure (mPAP) and pulmonary vascular resistance (PVR) with RHC; ii) evaluate…
- Trial name
- NCT02790918
- Testing
- 6MWT, Cardiovascular Magnetic Resonance Imaging (CMRI)
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Type 2 Diabetes Mellitus, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Lipid and Glycogen Metabolism in Patients With Impaired Glucose Tolerance and Calcium Sensing Receptor Mutations
Background: Type 2 diabetes mellitus is a main risk factor for cardiovascular disease and heart failure, in part due to diabetic cardiomyopathy.
- Conditions
- Type 2 Diabetes Mellitus, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Familiar Hypocalcuric Hypercalcemia, Healthy Volunteers
- Trial name
- RISC_7T (NCT02023489)
- Testing
- 1H/ 13C and 31P Magnetic Resonance Spectroscopy, Meal Tolerance Test, Hyperglycemic-hyperinsulinemic clamp
- Where
- Austria
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna