Clinical trials: Cardiac Magnetic Resonance
Stable Coronary Artery Disease, Cardiac Magnetic Resonance Imaging
Magnetic Resonance Adenosine Perfusion Imaging as Gatekeeper of Invasive Coronary Intervention
Current guidelines for the diagnosis and management of patients with stable coronary artery disease (CAD) strongly support the performance of non-invasive imaging techniques for the detection of myocardial ischemia prior to…
- Conditions
- Stable Coronary Artery Disease, Cardiac Magnetic Resonance Imaging, Coronary Angiography, Myocardial Revascularization
- Trial name
- MAGnet (NCT02580851)
- Testing
- diagnostic test - cardiac magnetic resonance imaging, diagnostic test - coronary angiography
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Ulm
Cardiovascular Disease, Mitral Valve Repair
Carbon Dioxide Insufflation on Cerebral Microemboli
The purpose of this study is to determine if blowing carbon dioxide into the surgical field during open-heart surgery to displace retained chest cavity air from the atmosphere will decrease the number of microembolic being…
- Conditions
- Cardiovascular Disease, Mitral Valve Repair, Cerebral Microemboli, Cognitive Decline
- Trial name
- NCT00715845
- Testing
- Carbon dioxide insufflation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Congenital Heart Disease
4-D Visualization Using Magnetic Resonance Imaging (MRI) in the Congenital Heart Disease Population
In this study, the investigators wish to use images obtained from standard of care cardiac MRI's performed at Children's Healthcare of Atlanta and transfer the images to a different computer in order to analyze them with a new…
- Trial name
- NCT00165945
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Emory University
Aortic Valve Stenosis
Use of Cardiac-MRI to Predict Results for People With Severe Aortic Stenosis
Background: Aortic valve stenosis is a disease that makes a major heart valve get smaller. This reduces heart function and causes death.
- Trial name
- NCT01905852
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
FAST Scan
Clinical Feasibility of Full Free-Breathing Cardiac Magnetic Resonance Imaging
To evaluate the feasibility, efficiency, and diagnostic concordance of a full comprehensive free-breathing cardiac magnetic resonance protocol with motion correction and sensing.
- Trial name
- NCT07395843
- Testing
- Free-breathing CMR
- Where
- China
- Volunteers
- 605 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Disease, CAD
Artifact-Free High-Resolution Myocardial Perfusion MRI in Subjects With Abnormal Nuclear Myocardial Perfusion Studies
This is a pilot study in a patient population with suspected coronary artery disease (CAD) as defined by the presence of a prior abnormal nuclear (PET/SPECT) myocardial perfusion scan.
- Trial name
- NCT01949844
- Testing
- regadenoson, Optimark®, Myocardial perfusion MRI
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Daniel S. Berman
Heart Diseases, Heart Failure
Fluid Status and T1-mapping by CMR
It is unclear to what extent systemic fluid overload has an impact on T1-mapping results by cardiovascular mangetic resonance imaging.
- Conditions
- Heart Diseases, Heart Failure, Valvular Heart Disease
- Trial name
- BCM-CMR-T1 (NCT03372512)
- Testing
- Bioimpedance spectroscopy
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna
Heart Failure
Brain Volume and Cardiac Function in Heart Failure
Patients with heart failure (HF) exhibit greater structural brain alterations and higher dementia risks than the general population.
- Trial name
- NCT06623344
- Testing
- Magnetic Resonance Imaging with or without Contrast
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Johns Hopkins University
The Focus of the Study is to Reduce the Risk of Stroke and Life-threatening Bleeding Events in Patients With Non-valvular Atrial Fibrillation
WATCHMAN FLX™ CT Study
WATCHMAN FLX™ CT is a prospective, single-arm, single-center, post-market investigation to assess device tissue coverage in subjects with non-valvular atrial fibrillation (AF) who receive the WATCHMAN FLX device to reduce the…
- Trial name
- NCT05324371
- Testing
- Watchman FLX Device
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Boston Scientific Corporation
Coronary Artery Disease
Effect of 6R-BH4 Treatment in Coronary Artery Disease (OXBIO Study)
The purpose of this study is to determine the effect of 6R-BH4 on vascular function in patients with coronary artery disease. We hypothesize that 6R-BH4 will improve vascular function in these patients.
- Trial name
- NCT00423280
- Testing
- 6R-BH4
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- University of Oxford
Tachycardia
China (CN)_Magnetic Resonance Imaging (MRI)_Implantable Cardiac Defibrillator (ICD) [CN_MRI_ICD]
This clinical study is to evaluate the safety and effectiveness of the Ellipse VR/DR implantable cardiac defibrillators (ICDs) and the Quadra Assura MP cardiac resynchronization therapy defibrillators (CRT-Ds), with Durata or…
- Trial name
- CN_MRI_ICD (NCT03828357)
- Testing
- Study MRI scan
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Abbott Medical Devices
Diabetes Mellitus Type 2, Diastolic Dysfunction
Effect of Liraglutide on Diastolic Dysfunction on Cardiac MRI in Type 2 Diabetes Patients
The purpose of this study is to determine whether liraglutide a GLP-1 analogue are effective in the treatment of diastolic dysfunction in type 2 diabetes patients analyzed by cardiac MRI.
- Conditions
- Diabetes Mellitus Type 2, Diastolic Dysfunction, Cardiac MRI, Myocardial Perfusion
- Trial name
- NCT02655770
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Type II Diabetes
Effects of GLP-1 Agonists on CArdiac Steatosis Evaluated by Magnetic Resonance Imaging
Type II diabetes is a known risk factor for heart failure, particularly through the progressive development of diabetic cardiomyopathy.
- Trial name
- LICAS-MR (NCT03498001)
- Testing
- GLP-1 agonists, Cardiac MRI, Follow up by phone
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Obesity
Effects of Exercise Mode on Cardiac Fat and Function
The overall goal of this project is to study the effects of exercise energy expenditure matched vigorous dynamic resistance training and aerobic training on cardiac fat, and its relationship to cardiac function and geometry using…
- Trial name
- NCT03297333
- Testing
- Resistance training, Aerobic interval training
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Southern Illinois University Edwardsville
Anomaly Heart, Turner Syndrome
Role of Cardiac AngioMR in Diagnosis of Cardiac and Vascular Anomalies in Adult Patients with Turner Syndrome
Considering the high prevalence of cardiovascular disease in Turner syndrome patients, noninvasive cardiac imaging is crucial for diagnosis and follow-up.
- Trial name
- NCT06178887
- Testing
- imaging
- Where
- Italy
- Volunteers
- 33 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Aortic Stenosis
Regression of Myocardial Fibrosis After Aortic Valve Replacement
Aortic stenosis (AS) is the most common valvular heart condition in the United Kingdom and the Western world. Surgery for severe AS prior to symptom onset is controversial.
- Trial name
- RELIEF-AS (NCT02174471)
- Where
- United Kingdom
- Volunteers
- 181 people
- Sponsor
- University College, London
Cerebral Infarction
Identification the Cause of Silent Cerebral infarctiON in Healthy Subjects (ICONS)
We hypothesized that paradoxical embolism may be one of the main mechanisms of silent cerebral infarction (SCI) located outside the perforating artery territory.
- Trial name
- ICONS (NCT01429948)
- Where
- South Korea
- Volunteers
- 581 people
- Sponsor
- Samsung Medical Center
Cardiac Sarcoidosis
Feasibility and Accuracy of Hybrid Magnetic Resonance and Positron Emission Tomography With 18F-Fluorodeoxyglucose in Diagnosing Cardiac Sarcoidosis
The purpose and objectives of the study is to establish the feasibility of the simultaneous PET/MR in patients with cardiac sarcoidosis, determine relationships between various imaging biomarkers like extracellular volume (ECV)…
- Trial name
- NCT03923049
- Testing
- hybrid PET/MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Alabama at Birmingham
Thalassemia, Non-transfusional-dependent Thalassemia (NTDT), Myeloplastic Dysplasia (MDS), Other Anemia
An Epidemiological Study to Assess Iron Overload Using MRI in Patients With Transfusional Siderosis (TIMES Study)
Iron, one of the most common elements in nature and the most abundant transition metal in the body, is readily capable of accepting and donating electrons.
- Trial name
- NCT01736540
- Testing
- MRI scan
- Where
- 13 sites in Australia
- Volunteers
- 243 people
- Sponsor
- Novartis Pharmaceuticals
Myocardial Infarction
Ferumoxytol for Magnetic Resonance Imaging of Myocardial Infarction
The investigators wish to examine whether a novel 'nanoparticle' of iron oxide, administered intravenously allows an area of heart muscle damage after heart attack to be visualised using a magnetic resonance scanner.
- Trial name
- NCT01323296
- Testing
- Ferumoxytol
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Edinburgh