Clinical trials: Cardiac Output
Pediatric ALL
Pediatric Cardiac Output Monitoring Observational Study
To assess Cardiac Output Monitoring in pediatric subjects by comparing FloTrac and ClearSight system to intermittent thermodilution Swan-Ganz, in order to expand the indications of FloTrac, ClearSight and Swan-Ganz thermodilution…
- Trial name
- POGO (NCT04465370)
- Testing
- Hemosphere Advanced Monitoring System, ClearSight 1.5, Swan-Ganz Catheter, Flotrac, Foresight
- Where
- 3 sites in United States
- Volunteers
- 89 people
- Sponsor
- Edwards Lifesciences
Heart Failure, Cardiac Output
Validation of CardioMEMS HF System Cardiac Output Algorithm IDE
The investigation will enroll subjects who have been previously implanted with the CardioMEMS™ Pulmonary Artery Sensor. This clinical investigation is twofold; in the first phase (development phase) data collected will be used to…
- Trial name
- VICTOR (NCT05428384)
- Testing
- MRI/ CardioMEMS comparison
- Where
- 8 sites in United States
- Volunteers
- 89 people
- Sponsor
- Abbott Medical Devices
Cardiac Output
The Smart Pump Study
To demonstrate that the Impella® Hemodynamic Platform (the "Study Device") is safe, and measurements obtained are as good as currently used methods.
- Trial name
- NCT04465201
- Testing
- Impella CP with Smart Assist (Circulatory Support System)
- Where
- 6 sites in United States
- Volunteers
- 35 people
- Sponsor
- Abiomed Inc.
Cardiac Output, Low
Comparison Studies Comparing Hemodynamic Parameters Provided by the Caretaker Against Respective Gold Standard References
Comparison studies comparing hemodynamic parameters provided by the Caretaker against respective Gold Standard references.
- Trial name
- NCT05035719
- Testing
- non-invasive cardiac output monitor
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CareTaker Medical LLC
Cardiac Output
Measurement of Cardiac Output Before and After Cardiopulmonary Bypass.
Cardiac output, the amount of blood pumped by the heart in one minute, will be measured in adults undergoing surgery involving cardiopulmonary bypass.
- Trial name
- NCT01103895
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Transonic Systems Inc.
Cardiac Output Measurements, Healthy Subjects
An Exploratory Clinical Study Non-invasive Monitoring of Cardiac Outputs
Pulsify Medical aims at developing a sensor designed for the non-invasive, continuous and real-time monitoring of cardiac hemodynamics in patients at risk based on new transducer technology and artificial intelligence.
- Trial name
- NCT05734664
- Testing
- Pulsify sensor, State-of-the-art ultrasound equipment
- Where
- Belgium
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pulsify Medical
Heart Failure Acute, Heart Failure
Cardiac Output Autonomic Stimulation Therapy for Heart Failure - Hemodynamic Effects
A single-arm study to observe NeuroTronik Cardiac Autonomic Nerve Stimulation (CANS) Therapy System hemodynamic and other physiologic effects.
- Trial name
- COAST-HF FX (NCT03542123)
- Testing
- NeuroTronik CANS Therapy® System
- Where
- Paraguay
- Volunteers
- 30 people
- Sponsor
- NeuroTronik Inc.
Heart Failure Low Output, Heart Failure
The Prelieve Trial - Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Heart Failure Patients
This study aims to investigate safety and efficacy of the Occlutech® AFR device in patients with HFrEF (Heart failure with reduced ejection fraction) and HFpEF (Heart failure with preserved ejection fraction)
- Trial name
- PRELIEVE (NCT03030274)
- Testing
- Occlutech AFR device
- Where
- 26 sites in Belgium, Germany and 1 more
- Volunteers
- 106 people
- Sponsor
- Occlutech International AB
Cardiac Output, Low
Cardiac Output Autonomic Stimulation Therapy for Heart Failure (COAST-HF) - Human NeuroCatheter Study
A single-center feasibility study in patients undergoing cardiac catheterization, to investigate the acute hemodynamic effects of transvenous cardiac autonomic nerve stimulation.
- Trial name
- COAST-HF HNrCS (NCT02880683)
- Testing
- NeuroTronik CANS Therapy System
- Where
- Paraguay
- Volunteers
- 16 people
- Sponsor
- NeuroTronik Inc.
Post Cardiac Surgery Patients
Measurement of Cardiac Output and Blood Volumes Using Transonic Ultrasound Dilution Technology
Measurement of the amount of blood pumped by the heart (cardiac output) and blood volumes in sick patients is important for doctors to better treat these patients.
- Trial name
- NCT00756119
- Where
- Russia
- Volunteers
- 26 people
- Sponsor
- Transonic Systems Inc.
Low Cardiac Output
The Efficacy of Hypertonic Lactate Solution in CABG(Coronary Artery Bypass Grafting) Patients
Previous clinical trials with 11.2% Hypertonic Ringer's Lactate in post-operative CABG subjects have shown an increase in several cardiac performance parameters, with lesser volume of resuscitation fluid required to reach…
- Trial name
- NCT00529711
- Testing
- Hypertonic lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Blood Pressure, Cardiac Output
Caretaker Hemodynamic Parameters Validation
Comparison studies comparing hemodynamic parameters provided by the Caretaker against respective Gold Standard references.
- Conditions
- Blood Pressure, Cardiac Output, Left Ventricular Ejection Time, Heart Rate Variability
- Trial name
- NCT04685733
- Testing
- Non-invasive hemodynamic measurements
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CareTaker Medical LLC
Intensive Care
Measurement of Cardiac Output and Intravascular Volume Status in Children Using COstatus (SH)
Assessment and monitoring of cardiac function in the pediatric intensive care unit (PICU) is an integral part of hemodynamic monitoring of critically ill patients whether it is done directly or indirectly.
- Trial name
- NCT01613859
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Transonic Systems Inc.
Cardiac Output
Accurate Measurement of Cardiac Output Using the Ultrasound Dilution Technique
Accurate cardiac output determination is a commonly used and important index of myocardial performance. The thermodilution method using a pulmonary artery catheter is the most common approach to cardiac output determination…
- Trial name
- BCM (NCT00851422)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Transonic Systems Inc.
Sudden Cardiac Death, Sudden Cardiac Arrest
Heart Failure Optimization Study
This study is designed as a multi-center prospective observational study of newly diagnosed Heart Failure (HF) patients to test the hypothesis that additional Ejection Fraction (EF) recovery occurs between 90 and 180 days as…
- Conditions
- Sudden Cardiac Death, Sudden Cardiac Arrest, Heart Failure, Heart Failure Low Output
- Trial name
- HF-Opt (NCT03016754)
- Testing
- Wearable Cardioverter Defibrillator
- Where
- 67 sites in United States, Austria and 2 more
- Volunteers
- 602 people
- Sponsor
- Zoll Medical Corporation
ICU, Pulmonary Artery Catheter (PAC)
The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial (Cardiac Output Study)
The purpose of this study is to compare cardiac output (CO), fluid responsiveness, and related measurements between the Philips AMC and PAC (Swan-Ganz) in ICU or surgical patients.
- Conditions
- ICU, Pulmonary Artery Catheter (PAC), Swan-Ganz Catheter
- Trial name
- CO (NCT06895603)
- Testing
- Philips Advanced Monitoring Cuff (AMC)
- Where
- 2 sites in United States, Germany
- Volunteers
- 75 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Sepsis
Cardiac Output Monitoring Managing Intravenous Therapy (COMMIT) to Treat Emergency Department Severe Sepsis
The primary objective of this study is to test whether a fluid resuscitation protocol guided by non-invasive hemodynamic measures reduces the progression of organ dysfunction (defined by an increase in the Serial Organ Failure…
- Trial name
- COMMIT (NCT01484106)
- Testing
- Fluid Resuscitation, Standard of Care
- Where
- 12 sites in United States
- Volunteers
- 65 people
- Sponsor
- Cheetah Medical Inc.
Heart Failure, Left Ventricular Dysfunction
PARACHUTE V PercutAneous Ventricular RestorAtion in Chronic Heart FailUre Due to Ischemic HearT DiseasE.
Prospective, multi-center, post-market, non-randomized, nested-control, observational study of the CE marked CardioKinetix Parachute Implant System.
- Trial name
- P5 (NCT02543632)
- Testing
- Parachute Implant System
- Where
- 10 sites in Germany
- Volunteers
- 85 people
- Sponsor
- CardioKinetix, Inc
Hemodynamic Monitoring
UltraTrac Clinical Pilot Study
This single-center pilot study will evaluate the accuracy and feasibility of non-invasive cardiac output measurement using the UltraTrac device in pediatric patients aged 0-21 years undergoing standard-of-care diagnostic cardiac…
- Trial name
- ULTRA-CO (NCT07864714)
- Testing
- Noninvasive Hemodynamic Monitoring System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- AcQumen Medical, Inc.
Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy
Comparison of Central Venous Oxygen Saturation Measurements by Non-invasive Mespere Venous Oximeter and Central Venous Catheter
The intent of this study is to validate the venous blood oxygenation measurements of the Mespere VA Oximeter compared to the saturations measured by venous blood sampling through an inserted central vein catheter, which is…
- Conditions
- Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy, Cardiogenic Shock Post Myocardial Infarction, Hypoxemic Respiratory Failure.
- Trial name
- NCT01788956
- Testing
- Mespere Venous Oximeter, Co-Oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mespere Lifesciences Inc.