Clinical trials: Cardiac Output
USCOM, Echocardiography
Comparison of the Ultrasonic Cardiac Output Monitor and Echocardiography for Hemodynamic Assessment in Pediatric Anesthesia
This prospective observational pilot study evaluates agreement between Ultrasound Cardiac Output Monitor (USCOM) measurements and transthoracic echocardiography-derived hemodynamic parameters in pediatric patients under…
- Conditions
- USCOM, Echocardiography, Echocardiography Guided Fluid Management
- Trial name
- NCT07342842
- Testing
- USCOM, Echocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Heart Defects, Congenital, Cardiopulmonary Bypass
Nesiritide Use Following Cardiac Surgery in Infants
The purpose of this study is to determine the effects of nesiritide on urine output and hemodynamics following cardiopulmonary bypass in infants. Safety and pharmacokinetic data will also be obtained.
- Trial name
- NCT00281671
- Testing
- nesiritide
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Boston Children's Hospital
Cardiac Physiology, Cardiac Output
The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation
The purpose of this study is to test the accuracy of a new noninvasive way to measure how much blood our heart pumps per minute.
- Trial name
- NCT00783679
- Testing
- NICO device
- Where
- United States
- Sponsor
- Massachusetts General Hospital
ECMO Treatment, ARDS
Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"
In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels.
- Conditions
- ECMO Treatment, ARDS, Pneumonia, Intensive Care
- Trial name
- NCT06593717
- Testing
- Transthoracic Echocardiography, Uncalibrated Pulse Contour Analysis, Transpulmonary Thermodilution/Calibrated Pulse Contour Analysis
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Enhanced External Counterpulsation (EECP), Cardiac Output
Impact of Enhanced External Counterpulsation (EECP) on Cardiac Force Index
Regular exercise can prevent cardiovascular disease, but there is also a risk of sudden cardiac death. Exercise-related sudden death often occurs unconsciously and there is no relevant monitoring mechanism.
- Conditions
- Enhanced External Counterpulsation (EECP), Cardiac Output, Cardiac Force Index
- Trial name
- NCT05080023
- Testing
- Enhanced External Counterpulsation (EECP)
- Where
- 5 sites in Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Chi-Ming Chu
Sepsis, Shock
Assessment of Transcutaneous Oxygen Tension/Oxygen Challenge Test in Intensive Care Unit (ICU) Patients
The lack of subcutaneous partial pressure of oxygen (PO2) rise in response to high fraction of inspired oxygen (FiO2), called the "oxygen challenge test (OCT)", was associated with higher morbidity and mortality in human…
- Trial name
- ICUPtO2OCT (NCT01174966)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Cardiogenic Shock
Study Comparing the Efficacy and Tolerability of Epinephrine and Norepinephrine in Cardiogenic Shock
The efficacy and tolerability of norepinephrine and epinephrine in cardiogenic shock after reperfused myocardial infarction will be compared, by following cardiac index evolution as main criteria.
- Trial name
- OptimaCC (NCT01367743)
- Testing
- epinephrine perfusion, norepinephrine perfusion
- Where
- 11 sites in France
- Volunteers
- 58 people
- Sponsor
- Central Hospital, Nancy, France
Heart Murmurs, Fever
Modifications of Heart Murmurs and Cardiac Output During Fever
The combination of fever and auscultation of a heart murmur suggests the diagnosis of endocarditis. However, fever itself increases cardiac output and could therefore modify heart sounds.
- Trial name
- FeMur (NCT04306991)
- Testing
- Auscultation using an electronic stethoscope (EKO CORE 4)
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Aneurysmal Subarachnoid Haemorrhage, SAH
Goal Directed Therapy After Aneurysmal Subarachnoid Haemorrhage
The objective of this study is to determine whether a goal-directed therapy can reduce the incidence of delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage.
- Trial name
- PiSAH (NCT01832389)
- Testing
- PiCCO
- Where
- Germany
- Volunteers
- 108 people
- Sponsor
- Technical University of Munich
Cardiac Disease, Cardiac Failure
Preoperative Infusion of Levosimendan in Patients Undergoing Cardiac Surgery
The aim of this retrospective study will be to investigate the effect of the preoperative administration of levosimendan on the outcome of patients with compromised cardiac function undergoing cardiac surgery
- Conditions
- Cardiac Disease, Cardiac Failure, Cardiac Surgery, Inotropes
- Trial name
- NCT04635293
- Testing
- preoperative infusion of levosimendan, no preoperative infusion of levosimendan
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aretaieion University Hospital
Cardiac Output, Low, Pediatric
Non-Invasive Cardiac Output Monitor in Children
This study will be the first of several studies that establish the value of measuring fluid responsiveness in children undergoing general anesthesia.
- Trial name
- NICOM2 (NCT03869606)
- Testing
- NICOM by Cheetah Medical
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pregnancy Related, Cardiac Output
Cardiac Flow Measurements in Pregnant Women by Non Invasive Techniques
the goal of this clinical trial is to compare the measurement of cardiac output, systolic ejection volume and vascular filling in pregnant women with the new non-invasive measurement techniques of the Index of contractility…
- Trial name
- NCT06114147
- Testing
- trans thoracic echocardiography measure, ICON measure, USCOM
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Pneumoperitoneum, Heart Output Disorder
Arterial and Plethysmographic Waveforms Variables as Predictors of Hemodynamic Response to Pneumoperitoneum
Laparoscopic surgery is frequently associated with hemodynamic changes due to pneumoperitoneum (PnP). Those complex hemodynamic changes are difficult to predict and occasionally they require active therapeutic interventions or…
- Trial name
- SPV-PnP (NCT01867814)
- Testing
- Pneumoperitoneum
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Carmel Medical Center
Heart Failure
Validation of Ejection Fraction and Cardiac Output Using Biostrap Wristband
In this study, the investigators will compare the accuracy of the Biostrap wristband, a wearable device with a clinical-grade Photoplethysmography (PPG) sensor, to measure ejection fraction and cardiac output in patients…
- Trial name
- NCT05279066
- Testing
- Biostrap Wristband
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Congenital Heart Disease
Multi-site Near Infrared Spectroscopy (NIRS) Monitoring of Children During Exercise
Near Infrared Spectroscopy (NIRS) monitoring has proven beneficial in increasing safety and improving patient care during pediatric cardiac surgery and during Pediatric Intensive Care Unit (PICU) stays.
- Trial name
- NCT00556231
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Medical College of Wisconsin
Heart Diseases
Evaluation of PCO2 and PO2 Values in the Pulmonary Artery and Superior Vena Cava
The study is about comparing blood samples obtained from the superior vena cava and the pulmonary artery. The investigators will compare the values of PCO2 and PO2 from these two sites, in order to see if exists a PCO2 gap and a…
- Trial name
- NCT03591029
- Testing
- blood samples
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Effects of; Anesthesia, in Pregnancy
Carbetocin Versus Oxytocin and Hemodynamic Effects
A randomized double-blind trial of oxytocin 5 u, carbetocin 100 µg and placebo with hemodynamic response as a primary outcome measure.
- Trial name
- NCT00977769
- Testing
- carbetocin 100 µg, oxytocin 5 u
- Where
- 2 sites in Norway
- Volunteers
- 76 people
- Sponsor
- Oslo University Hospital
Acute Heart Failure, Low Cardiac Output Syndrome
Exogenous Ketones for Acutely Decompensated HEart Failure
This study will evaluate whether supplementation of exogenous ketones in patients with severe left ventricular dysfunction and acutely decompensated heart failure requiring inotropic therapy would improve the patient's…
- Conditions
- Acute Heart Failure, Low Cardiac Output Syndrome, Hemodynamic Instability, Ketosis
- Trial name
- KADHEF (NCT04698005)
- Testing
- 25g Ketone monoester without added salts
- Where
- Czechia
- Volunteers
- 24 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Hemodynamic Changes in Pregnancy
Validation of a Non-invasive Hemodynamic Monitor (NexFin) in Pregnant Women
Blood pressure and cardiac output can be measured invasively in pregnant women. Non-invasive monitoring devices are desirable, but until now, no equipment has proven validity.
- Trial name
- NCT01861132
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Cardiac Output
The Smart Pump Study
To demonstrate that the Impella® Hemodynamic Platform (the "Study Device") is safe, and measurements obtained are as good as currently used methods.
- Trial name
- NCT04465201
- Testing
- Impella CP with Smart Assist (Circulatory Support System)
- Where
- 6 sites in United States
- Volunteers
- 35 people
- Sponsor
- Abiomed Inc.