Clinical trials: Cardiac Pacing, Artificial
Bradycardia, Congestive Heart Failure
The EASYTRAK EPI Clinical Investigation
The purpose of this study is to assess the safety and effectiveness of the EASYTRAK EPI lead.
- Trial name
- EASYTRAK EPI (NCT00158925)
- Testing
- EASYTRAK EPI lead
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Scientific Corporation
Pacemaker, Artificial, Cohort Studies
Morbidity, Mortality and Gender Differences in Patients With Pacemakers
Previous publications suggest gender difference in outcome parameters after pacemaker implantation. Aim of this study is to investigate gender differences in patients with pacemaker.
- Conditions
- Pacemaker, Artificial, Cohort Studies, Arrhythmias Requiring Therapy, Cardiac Pacing, Artificial
- Trial name
- NCT03388281
- Testing
- No intervention, retrospective analysis only.
- Volunteers
- 11,444 people
- Sponsor
- Medical University of Vienna
Sick Sinus Syndrome
Pacing of the Atria in Sick Sinus Syndrome Trial Preventive Strategies for Atrial Fibrillation
The purpose of this study is to determine which of 4 lead positions is most effective for pacemaker patients with Sick Sinus Syndrome in order to avoid development of atrial fibrillation.
- Trial name
- NCT00161538
- Testing
- Pacing leads to be implanted according randomization., Selection 9000 prevent AF an Diagnose AF
- Where
- 12 sites in Germany
- Volunteers
- 456 people
- Sponsor
- Medtronic BRC
Cardiac Pacing, Artificial, Aneurysm, Brain
Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain
Rapid ventricular pacing (RVP) is a technique to obtain flow arrest for short periods of time during dissection or rupture of the aneurysm. RVP results in an adequate fall of blood pressure which presents as an on-off phenomenon.
- Conditions
- Cardiac Pacing, Artificial, Aneurysm, Brain, Arteriovenous Malformations, Cerebral
- Trial name
- NCT03281395
- Testing
- Rapid ventricular pacing (RVP), No rapid ventricular pacing
- Where
- Belgium
- Volunteers
- 27 people
- Sponsor
- University Hospital, Antwerp
Heart Failure, Cardiomyopathy, Dilated
Randomized Comparison of Endocardial Versus Epicardial - From the Coronary Sinus - Left Ventricular Pacing for Resynchronization in Heart Failure.
Biventricular pacing is a validated treatment for patients suffering from heart failure resistant to medical treatment. However, up to 30% of the patients are non responsive to this strategy using the coronary sinus approach to…
- Conditions
- Heart Failure, Cardiomyopathy, Dilated, Coronary Disease
- Trial name
- EPI-ENDO (NCT01260402)
- Testing
- Resynchronization using a transeptal approach, Resynchronization using a coronary sinus approach
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Bordeaux
Bradycardia, Atrioventricular Block
Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal Capture
This is a prospective, multicenter, randomized controlled trial designed to determine whether direct capture of the left ventricular conduction system must be achieved as the procedural endpoint of left bundle branch area pacing…
- Conditions
- Bradycardia, Atrioventricular Block, Sick Sinus Syndrome, Cardiac Pacing
- Trial name
- COMPARE-SYNC (NCT07804394)
- Testing
- LBBAP with mandatory left ventricular conduction system capture (LBBP or LFP), LBBAP with left ventricular septal capture as the accepted procedural endpoint (LVSP)
- Volunteers
- 300 people
- Sponsor
- Yonsei University
Heart Failure, Cardiac Pacing, Artificial
Acute Effects of LBBP Versus BVP for CRT
The study was designed to compare the acute effects of left bundle branch pacing (LBBP) with biventricular pacing (BVP) in patients with left ventricular ejection fraction (LVEF) <=35% with left bundle branch block (LBBB).
- Conditions
- Heart Failure, Cardiac Pacing, Artificial, Cardiac Resynchronization Therapy
- Trial name
- NCT04505384
- Testing
- left bundle branch pacing, biventricular pacing
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Shanghai Zhongshan Hospital
Atrioventricular Block, Pacing-Induced Cardiomyopathy
Conduction System Pacing to Prevent Pacing-Induced Cardiomyopathy
The purpose of this randomized, open-label trial was to determine whether permanent conduction system pacing preserves left ventricular function and reduces the incidence of pacing-induced cardiomyopathy compared with…
- Conditions
- Atrioventricular Block, Pacing-Induced Cardiomyopathy, Cardiac Pacing, Artificial
- Trial name
- PRESERVE-CSP (NCT07831655)
- Testing
- Conduction System Pacing, Right Ventricular Apical Pacing
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Germans Trias i Pujol Hospital
Cardiac Pacing, Artificial, Tricuspid Valve Regurgitation, Non-rheumatic
Cardiac Implantable Electronic Device- Induced Remodelling of Tricuspid Valve and Right Chambers
This single-center longitudinal study aims to evaluate the occurrence and clinical impact of tricuspid regurgitation (TR) after cardiac-implanted-electronic-device (CIED) implantation by comprehensive echocardiographic…
- Trial name
- CIED-REMTRIC (NCT06914570)
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Istituto Auxologico Italiano
Cardiac Pacing, Artificial
Closed Loop Stimulation, Cognitive Performance, and Quality of Life in Pacemaker Patients
The purpose of this study is to compare the influence of accelerometer-based rate adaptation and Closed Loop Stimulation on cognitive performance and quality of life in pacemaker patients.
- Trial name
- COGNITION (NCT00323661)
- Testing
- Rate-adaptive pacemaker: accelerometer, Rate-adaptive pacemaker: Closed Loop Stimulation
- Where
- 55 sites in Australia, Austria and 8 more
- Volunteers
- 405 people
- Sponsor
- Biotronik SE & Co. KG
Cardiac Pacing, Artificial, Cardiac Pacemaker, Artificial
BIO|MASTER.CSP Study
The goal of this clinical study is to test the clinical safety and performance of the Amvia pacemakers and the Solia CSP S lead when used for left bundle branch area pacing (LBBAP).
- Conditions
- Cardiac Pacing, Artificial, Cardiac Pacemaker, Artificial, Cardiac Resynchronization Therapy Devices, Bradycardia
- Trial name
- NCT06620237
- Testing
- Implantation of the Solia CSP S pacing lead for LBBAP
- Where
- 14 sites in Australia, Belgium and 3 more
- Volunteers
- 152 people
- Sponsor
- Biotronik SE & Co. KG
Heart Failure, Cardiomyopathy, Dilated
Role of Left Ventricular Pacing Site
Cardiac resynchronization therapy has been shown to be effective in reducing symptoms and mortality in heart failure patients. However, very few is known about the importance of the left ventricular pacing site.
- Conditions
- Heart Failure, Cardiomyopathy, Dilated, Coronary Disease
- Trial name
- NCT00221780
- Testing
- left ventricular pacing
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Bordeaux
Heart Failure
Stem Cells and Resynchronization Cardiac
Same patients with dilated myocardiopathies with large areas of fibrosis has not been as successful after Cardiac Resynchronization Therapy, for Heart Failure patients in functional class III or IV.
- Trial name
- RCT and SCT (NCT00800657)
- Testing
- Pacing and Stem Cells Implantations., Pacing and Stem Cells Implantation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto de Molestias Cardiovasculares
Atrioventricular Block
Ventricular Pacing Site Selection (V-PASS)
The purpose of this study is to determine whether there is a relationship between ventricular lead position and the incidence of heart failure and atrial fibrillation in patients with indication for permanent pacemaker…
- Trial name
- NCT00292383
- Testing
- Leads to be implanted according randomization on specified sites. Vitatron pacemakers to be implanted: T60 DR, T70 DR, T20 SR, C60 DR
- Where
- 3 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Medtronic BRC
Cardiac Pacing, Artificial, Cardiac Resynchronization Therapy
Electrical Resynchronization and Acute Hemodynamic Effects of Direct His Bundle Pacing Compared to Biventricular Pacing
The aims are to compare Direct His Bundle Pacing (DHBP) with biventricular pacing (BiV) in terms of electrical resynchronization using electrocardiographic imaging (ECGI) and also in terms of acute hemodynamical effect using…
- Conditions
- Cardiac Pacing, Artificial, Cardiac Resynchronization Therapy, Direct His Bundle Pacing
- Trial name
- NCT03452462
- Testing
- Pacing
- Where
- Switzerland
- Volunteers
- 19 people
- Sponsor
- University Hospital, Geneva
Pacemaker, Leadless Pacemaker
Leadless Pacemaker Registry: Outcomes and Follow-up From the University Hospital of St. Pölten
The registry for leadless pacemakers will collect and annually analyze the data of all leadless pacemaker implantations at the University Hospital St.
- Conditions
- Pacemaker, Leadless Pacemaker, Cardiac Pacing, Artificial, Registries
- Trial name
- LPR (NCT07246135)
- Where
- Austria
- Volunteers
- 700 people
- Sponsor
- Karl Landsteiner University of Health Sciences