Clinical trials: Cardiac Risk Factors
Coronary Artery Disease, Cardiovascular Risk Factor
Correlation of Genetic Polymorphisms and Clinical Parameters With the Complexity of Coronary Artery Disease
The purpose of the research project is to investigate the potential association of 6 genetic polymorphisms with the complexity and the severity of coronary artery disease (SYNTAX score).
- Conditions
- Coronary Artery Disease, Cardiovascular Risk Factor, Coronary Arteriosclerosis
- Trial name
- NCT03315234
- Testing
- SNPs associated with CAD
- Where
- Greece
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Cardiomyopathy
Cardiomyopathy Following Stem Cell Transplantation
This study will examine the incidence of cardiac complications, particularly cardiomyopathy, in patients who have undergone allogeneic (donor) stem cell transplantation at NIH.
- Trial name
- NCT00352209
- Where
- 2 sites in United States
- Sponsor
- National Institutes of Health Clinical Center (CC)
Stroke, Acute, Atrial Fibrillation
SAMURAI-NVAF Study: Anticoagulant Therapy for Japanese Stroke Patients With Nonvalvular Atrial Fibrillation (NVAF)
The purpose of this study is to determine choice of anticoagulant therapy during acute and chronic stages of ischemic stroke/TIA and short- and long-term outcomes, including stroke recurrence and bleeding complications, in…
- Trial name
- SAMURAI-NVAF (NCT01581502)
- Testing
- This is an observational study.
- Where
- 16 sites in Japan
- Volunteers
- 1,000 people
- Sponsor
- Ministry of Health, Labour and Welfare, Japan
Cardiovascular Risk Factor
Effect of a Low Calorie Diet Containing Nuts on Systemic and Vascular Inflammation
Accumulating evidence from prospective observational studies and a large clinical trial suggests that nut intake lowers the risk of cardiovascular disease (CVD).
- Trial name
- NCT04078919
- Testing
- Nut consumption, Low calorie diet
- Where
- Iran
- Volunteers
- 67 people
- Sponsor
- Shahid Beheshti University
Coronary Artery Disease
Evaluation of Radiation Exposure and Risk Factors During Coronary Angiography
The purpose of this study is to evaluate the radiation exposure in patients undergoing coronary angiography, and to identify reference values for the main radiation doses parameters.
- Trial name
- EARTH (NCT02892539)
- Testing
- Coronary Angiography
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Fan Liu
Hypertension, Diabetes
A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti
Investigators will establish a longitudinal cohort of ~3,000 adults >18 years in Port-au-Prince using multistage random sampling, and follow them longitudinally to evaluate the prevalence and incidence of cardiovascular disease…
- Conditions
- Hypertension, Diabetes, Obesity, Kidney Diseases
- Trial name
- NCT03892265
- Testing
- Observational Study
- Where
- Haiti
- Volunteers
- 3,005 people
- Sponsor
- Weill Medical College of Cornell University
Hyperbilirubinemia, Hepatic Impairment
The Investigation of the Causes of Hepatic Dysfunction in the Postoperative Period During Open-heart Surgeries
In a prospective observational study during the six-month duration, coronary artery bypass graft surgery (CABG) and valve repair surgery (mitral, mitral, and aortic valve and/or tricuspid valve) patients were investigated for…
- Conditions
- Hyperbilirubinemia, Hepatic Impairment, Surgery, Cardiac Disease
- Trial name
- NCT04271098
- Testing
- Open-Heart Surgery for nine months duration, Relation between possible risk factors and hyperbilirubinemia, Follow-up period
- Volunteers
- 340 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Atrial Fibrillation Paroxysmal
Atrial Fibrillation Lifestyle Project
The objectives of the investigators are to demonstrate a reduction in frequency and symptoms of AF and improvements in cardiovascular risk factors following a lifestyle intervention in patients with paroxysmal AF.
- Trial name
- ALP (NCT03724383)
- Testing
- Risk Factor Management Consult, Diet Classes, Stress Management Classes
- Where
- 7 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Teddi Orenstein Lyall
Postoperative Delirium, Postoperative Cognitive Dysfunction
Risk Factor of POD and POCD After Cardiac Surgery
Postoperative delirium (POD) and postoperative cognitive decline (POCD) are common after surgeries in the elderly, especially after cardiothoracic surgery.
- Trial name
- NCT03635229
- Where
- Thailand
- Volunteers
- 360 people
- Sponsor
- Mahidol University
Cardiac Surgical Procedures, Pediatrics
Bayesian Networks in Pediatric Cardiac Surgery
Pediatric cardiac surgery with cardiopulmonary bypass is associated with significant morbidity and mortality. Also score systems for risk factors, such as Risk Adjustment for Congenital Heart surgery (RACHS 1) score or the…
- Conditions
- Cardiac Surgical Procedures, Pediatrics, Cardiopulmonary Bypass
- Trial name
- NCT05537168
- Testing
- Pediatric cardiac surgery under cardiopulmonary bypass
- Where
- Belgium
- Volunteers
- 1,364 people
- Sponsor
- Brugmann University Hospital
Viral Myocarditis, Cardio-Renal Syndrome
Risk Factors for Predictors of In-hospital Death in Acute Fulminant Myocarditis
The investigators performed a retrospective, single-center observational study, and the participants with acute fulminant myocarditis were included.Then, the investigator analyzed the risk factors of in-hospital death in these…
- Conditions
- Viral Myocarditis, Cardio-Renal Syndrome, Risk Factor, Cardiovascular
- Trial name
- NCT03219996
- Testing
- prognosis
- Volunteers
- 76 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Hypogonadism, Atherosclerosis
Testosterone Replacement in Older Men and Atherosclerosis Progression
As men grow older, their testosterone levels decrease with age. One-third of men, 70 years of age or older, have low testosterone levels.
- Trial name
- TEAAM (NCT00287586)
- Testing
- Testosterone Gel (Androgel)
- Where
- 3 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Atrial Fibrillation
Prevalence of Sub-Clinical Atrial Fibrillation Using an Implantable Cardiac Monitor
The primary objective of the study is to determine the rate of detection of sub-clinical atrial fibrillation (≥ 5 minutes)within an average of 12 months following implant of the St.
- Trial name
- ASSERT-II (NCT01694394)
- Testing
- Implantable Cardiac Monitor (Confirm ICM model 2102)
- Where
- 19 sites in Canada, Netherlands
- Volunteers
- 256 people
- Sponsor
- Population Health Research Institute
Coronary Artery Disease, Cardiometabolic Risk Factors
Impact of New Anthropometric Indices on Outcomes After Cardiac Surgery
Obesity is associated with a number of risk factors for cardiovascular disease. Body mass index (BMI) is the most commonly recommended and used anthropometric measure to classify general obesity in clinical and epidemiological…
- Conditions
- Coronary Artery Disease, Cardiometabolic Risk Factors, Cardiac Anesthesia, Cardiac Surgery
- Trial name
- NCT05403294
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
HIV Infections
Endothelial Dysfunction as a Risk Factor in HIV Study
Highly active antiretroviral therapy (HAART) has proven effective in altering the natural history of HIV infection in many patients. However, this therapy may not be sustainable because of the toxicities of the medications.
- Trial name
- NCT00039663
- Testing
- Pravastatin, Gemfibrozil, Rosiglitazone
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Coronary Artery Disease
Effects of Beta-Blocker Therapy and Phosphodiesterase Inhibition on Cardiac Neurohormonal Activation
Previous clinical investigations have demonstrated the utility of β-adrenergic blockade in reducing perioperative ischaemic events, ultimately translating into a decrease in cardiac morbidity and mortality.
- Trial name
- NCT00348101
- Testing
- Combined therapy with enoximone and esmolol
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- Klinikum Ludwigshafen
Goal Directed Therapy, Postoperative Morbidity
Risk Factors for Postoperative Complications in Major Non-cardiac Surgery: Post-hoc Analysis of the OPHIQUE Multicentre Study
Post-operative morbidity and mortality is related to many factors related to the patient's condition, the intra-operative period and the optimisation of intra-operative haemodynamic and respiratory parameters.
- Conditions
- Goal Directed Therapy, Postoperative Morbidity, Individualised Target, Postopera Mortality
- Trial name
- MULTIPAS (NCT05824260)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cerebrovascular Accident, Transient Ischemic Attack
The Post Stroke Preventive Trial (PREVENT). A RCT Nested in a Cohort Study
Patients with a diagnosis of stroke or TIA, who are already included in the RIALTO-cohort study are asked to participate in a RCT after discharge from hospital.
- Conditions
- Cerebrovascular Accident, Transient Ischemic Attack, Myocardial Infarction
- Trial name
- PREVENT (NCT00253097)
- Testing
- Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 353 people
- Sponsor
- Hvidovre University Hospital
Heart Failure With Preserved Ejection Fraction
Risk Factors In Heart Failure Patients With Preserved Ejection Fraction
This study aimed to identify the independent risk factors associated with heart failure readmission, cardiac mortality and all-cause death among patients discharged from Xiangtan Central Hospital with heart failure and preserved…
- Trial name
- RIPE-HF (NCT06487468)
- Volunteers
- 9,419 people
- Sponsor
- Xiangtan Central Hospital
Coronary Artery Disease
Programme to Optimise Risk Factors in Patients Waiting for Coronary Artery Bypass Surgery
The time spent waiting for heart surgery can be extremely stressful. This programme aims to address this by providing a home-based, nurse-led support and education programme.
- Trial name
- NCT00124371
- Testing
- a nurse led home-based education and support programme
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust