Clinical trials: Cardiac Sound
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Noisy Environment
This study aims to examine whether listening to natural sounds in a noisy (traffic) environment compared to traffic noise only impacts behavioural, cognitive, affective, and physiological markers associated with attention…
- Conditions
- Cognitive Fatigue, Mental Fatigue, Heart Rate Variability, Skin Conductance
- Trial name
- EARS (NCT05009784)
- Testing
- Baseline, Fatigue Manipulation, Traffic Sound
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Hearing Loss, Noise-Induced, Hearing Loss
Apple Hearing Study
The Apple Hearing Study is a partnership between the University of Michigan and Apple to study sound exposure and its impact on hearing health.
- Conditions
- Hearing Loss, Noise-Induced, Hearing Loss, Tinnitus
- Trial name
- AHS (NCT04172766)
- Where
- United States
- Volunteers
- 300,000 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Cardiac Disease, Auscultation of Heart
Digital diagnoSis of Cardiac sOUNd in peDiatric Patients [DI-SOUND Study]
Neonatal screening procedures for potentially life-threatening congenital cardiovascular diseases (i.e., duct-dependent systemic or pulmonary circulation), currently implemented at the national level, rely primarily on…
- Conditions
- Cardiac Disease, Auscultation of Heart, Machine Learning
- Trial name
- DI-SOUND (NCT07542509)
- Where
- 5 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Heart Failure, Crackles
Heart Failure Monitoring With Eko Electronic Stethoscopes
This proof-of-concept study will evaluate the feasibility of the Eko DUO to measure signals relevant to heart failure (HF) decompensation, as well as the feasibility to develop an algorithm to model hemodynamic filling pressures…
- Conditions
- Heart Failure, Crackles, Heart Failure With Preserved Ejection Fraction
- Trial name
- HOME0 (NCT04404452)
- Testing
- Use of Eko CORE and Eko DUO electronic stethoscopes
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Eko Devices, Inc.
Heart Failure
KV-PREDICT Diagnostic Device in Patients With Heart Failure
This is a pilot, single-center, non-invasive interventional study evaluating the performance of KV-PREDICT, an investigational diagnostic medical device (Class IIa, not CE-marked), in adult patients with heart failure.
- Trial name
- PREDICT_HF (NCT07805213)
- Testing
- KV-PREDICT
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- KardioVis S.r.l.
Heart Murmurs, Wheezing
Validate the Efficacy and the Safety of the Keikku Electronic Stethoscope for Its Indication and Intended Purpose, Under the Intended Conditions of Use.
This study is testing a digital stethoscope called the Keikku electronic stethoscope. Doctors use stethoscopes to listen to the heart, and this new device records heart sounds using a smartphone app.
- Trial name
- KCI-1 (NCT07044128)
- Testing
- Digital stethoscope using MEMS sensor and mobile application for cardiac auscultation
- Where
- Peru
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Lapsi Health Holding B.V.
Heart Failure
Nanowear Heart Failure Management Multi-sensor Algorithm
The NanoSense study is a multi-center, prospective, non-randomized, observational, feasibility, non-significant risk study. The NanoSense study will enroll up to 500 subjects in up to 10 centers in order to collect data which…
- Trial name
- Nanosense (NCT03719079)
- Testing
- SimpleSENSE
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Nanowear Inc.
Coronary Artery Disease, Atherosclerosis
SYNergy Stent® System Implantation With Mandatory Intra-VascularUltra-Sound Guidance and Dual Anti-Platelet Therapy
The purpose of this study is to see if one month of dual antiplatelet therapy (DAPT) combined with the placement of the Synergy® Stent with IVUS (intravascular ultrasound) is safe for patients who are at high risk of bleeding…
- Conditions
- Coronary Artery Disease, Atherosclerosis, Stent Placement
- Trial name
- SYNIVUS-DAPT (NCT03606642)
- Testing
- Dual Antiplatelet (DAPT) Therapy, The Synergy® stent
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- HonorHealth Research Institute
Prader-Willi Syndrome
Optimizing the Social Engagement System in Prader-Willi Syndrome: Insights From the Polyvagal Theory
The Polyvagal Theory focuses on how function and structure changed in the vertebrate autonomic nervous system during evolution. The theory is named for the vagus, a major cranial nerve that regulates bodily state.
- Trial name
- NCT03101826
- Testing
- Listening Project Protocol
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Indiana University
Prenatal Attachment, Maternal Expectations, Paternal Involvement
Effect of Partner-Conducted Fetal Heart Sound Measurement on Maternal and Paternal Attachment
This randomized controlled study aims to evaluate the effect of fetal heart sound (FHS) measurement performed by the partner on prenatal maternal and paternal expectations and attachment levels.
- Trial name
- FHS-ATTACH (NCT06965647)
- Testing
- Partner-Conducted Fetal Heart Sound Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
Neonatal Intensive Care, Preterm
The Effect of Simulated Intrauterine Sound Applied to Preterms
Preterm infants lack intrauterine sounds suitable for their development as they are born early. In addition, they are exposed to many unfamiliar sounds for weeks or months in the neonatal intensive care unit (NICU) where their…
- Trial name
- NCT05806320
- Testing
- Intrauterine Sound Listening Group 1, Intrauterine Sound Listening Group 2
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Neonatal, Pain
The Effect of Music, White Noise and Heart Sound on Neonatal Pain
Infants are exposed to many painful procedures during their stay in the Neonatal Intensive Care Unit (NICU). Some epidemiological studies report that infants experience an average of 7.5-14 painful procedures per day per infant…
- Trial name
- NCT05828420
- Testing
- White noise, Heart sound, Music
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Heart Failure
Ultra-sound Assisted Management of Heart Failure
The purpose of this study is to evaluate the impact of using hand carried ultrasound measurements of volume status in directing treatment of heart failure patients admitted with acute exacerbation.
- Trial name
- USA-HF (NCT04376424)
- Testing
- Hand Held Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Heart Failure
Sound Heart Spiritual Combined With Dhikr for Patients With Heart Failure
Heart failure can cause persistent fatigue, impaired quality of life, and spiritual distress. This interventional study will evaluate a 12-week Sound Heart Spiritual intervention combined with dhikr (SHS-Zikir) among Muslim…
- Trial name
- SHS-ZIKIR (NCT07795632)
- Testing
- Sound Heart Spiritual Intervention Combined With Dhikr
- Volunteers
- 60 people
- Sponsor
- Risqi Wahyu Susanti
Heart Diseases
Comparison of Stethee® to the Conventional Stethoscope for Auscultation of Simulated Heart Sounds
The objective of this study is to compare the relative capability of Stethee® (new wireless digital stethoscope) and 3M™ Littmann® Classic III™ (conventional stethoscope) in the identification of manikin-simulated heart sounds by…
- Trial name
- STELIT (NCT03344874)
- Testing
- Stethee®, 3MTM Littmann® Classic IIITM
- Where
- Malaysia
- Volunteers
- 104 people
- Sponsor
- Clinical Research Centre, Malaysia
Chest Pathology
Comparison of NoaScope to the Conventional Stethoscope for Auscultation of Heart and Lung Sounds
Assessing non-inferiority of a newly developed electronic stethoscope NoaScope in comparison with the conventional 3M Littmann stethoscope
- Trial name
- NCT05252130
- Testing
- NoaScope
- Where
- Pakistan
- Volunteers
- 47 people
- Sponsor
- Innova Smart Technologies (Pvt.) Ltd
Pain, Pain, Postoperative
Peter Hess® Sound Massage for Reducing Anxiety and Pain in Cardiac Surgery
Cardiac surgery patients often undergo anxiousness and pain. Before surgery, anxiety is often caused by the idea of sternotomy, extracorporeal circulation, fear of post-operative pain, and even death.
- Conditions
- Pain, Pain, Postoperative, Pain, Chest, Anxiety
- Trial name
- MuSoCa (NCT05204043)
- Testing
- Peter Hess® sound massage, Music relaxation Music Care®, Questionnaires
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Young Earthquake Survivors
Biofeedback With Heart Sound Following Trauma
The Project aims to assess the long-term risk of trauma-induced stress in young persons. Using non-invasive sound therapy to assess the effects on the vagal nerve via cardiovascular effects and neural activity will provide…
- Trial name
- NCT06919055
- Testing
- PCG auditory stimulation, MHR stimulation, Control-no treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Fatma Özcan
Insomnia, Insomnia Chronic
Efficacy and Accuracy of an AI-Driven Sleep Earbud for Chronic Insomnia
This study evaluates a new smart sleep earbud designed to help adults suffering from chronic insomnia. The device uses artificial intelligence (AI) to track a user's real-time heart rate and movement through the ear canal…
- Conditions
- Insomnia, Insomnia Chronic, Insomnia Disorders, Sleep Wake Disorders
- Trial name
- NCT07744581
- Testing
- AI-driven Neuromodulation Music (NeuroRhythm)
- Where
- 2 sites in China
- Volunteers
- 25 people
- Sponsor
- The Chinese University of Hong Kong, Shenzhen
Atrial Fibrillation (AF), OSA - Obstructive Sleep Apnea
Impact of Atrial Fibrillation Ablation on Sleep Parameters.
Assessment of Sleep Parameters Using Polygraphy in Patients with Paroxysmal Atrial Fibrillation Qualified for Pulmonary Vein Isolation - A Prospective Observational Study: Afib Ablation and Hypopnea Index - The "AAHI" Study…
- Conditions
- Atrial Fibrillation (AF), OSA - Obstructive Sleep Apnea, Pulmonary Vein Isolation
- Trial name
- AAHI (NCT07259200)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Primula Clinics