Clinical trials: Cardiac and Respiratory Arrest
Cardiac Arrest, Ischemia Reperfusion Injury
Hypertonic Lactate After Cardiac Arrest
The study is intended to test the hypothesis that sodium lactate infusion after resuscitation from a cardiac arrest will decrease the magnitude of brain damage, as measured by the serum biomarker concentration of NSE.
- Conditions
- Cardiac Arrest, Ischemia Reperfusion Injury, Anoxic Brain Injury
- Trial name
- LATTE (NCT05004610)
- Testing
- Sodium Lactate Solution
- Where
- Belgium
- Volunteers
- 125 people
- Sponsor
- Erasme University Hospital
Out-Of-Hospital Cardiac Arrest, Oxygen Toxicity
ORI to Reduce Hyperoxia After Out Hospital Cardiac Arrest
The investigator's research proposal is a randomized controlled study evaluating two different monitoring strategies to titrate FiO2 in order to rapidly and safely achieve optimal SatO2 targets during early ROSC of non-traumatic…
- Trial name
- ORI-ONE (NCT03653325)
- Testing
- ORI measurement, oxygen saturation measurement
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Critical Illness, Cardiac Arrest
Swecrit Biobank - Blood Samples From Critically Ill Patients and Healthy Controls
Blood samples are collected and stored in a biobank for later analysis of circulating substances in peripheral blood and genetic variations in patients with severe critical illness and risk of death.
- Conditions
- Critical Illness, Cardiac Arrest, Sepsis, Influenza
- Trial name
- SWECRIT (NCT04974775)
- Testing
- Blood collection, Blood collection, serial sampling
- Where
- 4 sites in Sweden
- Volunteers
- 8,500 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Syncope, Arrest
Urgent Medical and Surgical Conditions During Flights
The aim of this study is to evaluate the incidence and status of urgent medical conditions. After defining the urgent situations, the investigators will evaluate the adequacy of the standard medical kits and trainings.
- Conditions
- Syncope, Arrest, Vertigo, Pain
- Trial name
- NCT02457455
- Where
- Turkey (Türkiye)
- Volunteers
- 1,312 people
- Sponsor
- Antalya Training and Research Hospital
Cardiac Arrest
Respiratory Parameters Using Advanced Airways During In-hospital Cardiac Arrest
The investigators aim to investigate the real life volumes of air delivered to the lungs when rescuers deliver these breaths by hand as part of resuscitation attempts during cardiac arrest.
- Trial name
- NCT06580652
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Royal United Hospitals Bath NHS Foundation Trust
Out-Of-Hospital Cardiac Arrest, Trauma
AI to Improve Data From Danish Cardiac Arrest Registry
Out-of-hospital cardiac arrest is a leading cause of death worldwide and patient outcome vary substantially throughout regions suggesting further evaluation and potential for improvement.When focussing on subgroups of OHCA, data…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Trauma, Drug Overdose, Electrocution
- Trial name
- NCT05308303
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Cardiac Arrest
Intra-Arrest-Ventilation in Human Cadavers
The study investigates the influence of non-synchronized bag-device-ventilation and intermittent positive pressure ventilation (IPPV), as recommended in the current resuscitation guidelines of the European Resuscitation Concil…
- Trial name
- NCT06306898
- Testing
- Endotracheal Intubation, Laryngeal tube, Laryngeal mask
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Gerrit Jansen
Out-Of-Hospital Cardiac Arrest
Ventilation Monitoring in OHCA
This is a before-and-after study examining the impact of real-time ventilation monitoring during out-of-hospital cardiac arrest.
- Trial name
- NCT04988906
- Testing
- Zoll Accuvent Ventilation Monitor
- Where
- Canada
- Volunteers
- 412 people
- Sponsor
- Sunnybrook Health Sciences Centre
Out-Of-Hospital Cardiac Arrest, Foreign Body Aspiration
Foreign Body Airway Obstruction, Incidence, Survival EMS-treatment and First Aid Treatment by Laypersons
Background: Foreign body airway obstruction (FBAO) is often described as an uncommon cause of Out of Hospital Cardiac Arrest (OHCA) accounting for approximately 1.4% of all OHCA.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Foreign Body Aspiration, Cardiopulmonary Arrest
- Trial name
- NCT04279860
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Cardiac Arrest (CA), Hypoxic-Ischemic Brain Injury
Identification of Brain Injury Using Portable MRI
The goal of this study is to look for brain injury in patients who had a cardiac arrest, using portable brain imaging. The portable nature of this test will also allow for serial imaging so the investigators can understand how…
- Trial name
- NCT07197918
- Testing
- portable MRI scanner
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Hypoxic Ischemic Encephalopathy
Targeted Temperature Management After In-Hospital Cardiac Arrest
The purpose of this study is to determine whether targeted temperature management at 36.0˚C(TTM-36) in patients who remain unconscious after resuscitation from in-hospital cardiac arrest(IHCA) will reduce death and disability…
- Trial name
- TTM36-IHCA (NCT02578823)
- Testing
- Arctic Sun®, Arcticgel™, Conventional antipyretic treatment
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center