Clinical trials: Cardio Vascular Disease, open to volunteers
Cardio Vascular Disease
Evaluation of the Benefits of Hypnosis During Transoesophageal Echocardiography
Transoesophageal echocardiography (TOE) is a routine cardiology examination that is performed in most cases under local anaesthesia and is recommended for many indications.The objective of our study will be to evaluate the…
- Trial name
- HYPNOECHO (NCT07512830)
- Testing
- conversational hypnosis
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Cardiovascular Diseases (CVD), Cerebro Vascular Disease
Identifying Risk Factors and Predicting Future Health Outcomes for Korean Patients With Heart and Blood Vessel Diseases: A Long-term Follow-up Study
This study aims to establish a comprehensive, long-term clinical registry infrastructure for heart and brain vascular diseases (cardiovascular diseases and stroke) at Samsung Medical Center.
- Trial name
- NCT07393412
- Testing
- Standard Medical Therapy, Revascularization Procedures, Lifestyle Modification
- Where
- South Korea
- Volunteers
- 800,000 people
- Sponsor
- Samsung Medical Center
Cardiac Disease
Dynamic Cardio-vascular, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects
IDEALE aims to assess the status of autonomic function, cerebral autoregulation (CA) and cortical activity in healthy subjects and correlate these functions with the psychological dimension of the subjects.
- Trial name
- IDEALE (NCT06785181)
- Testing
- Active standing
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Exercise Behavior, Multiple Myeloma
Exercise Phenotyping Prior to Chemotherapy in Newly Diagnosed Multiple Myeloma (MM-Exercise)
MM-Exercise is a prospective, single-centre, observational pilot study of patients with newly diagnosed multiple myeloma who have not yet started chemotherapy and whose resting echocardiogram is unremarkable or only mildly…
- Trial name
- MM-Exercise (NCT07851493)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Technical University of Munich
Hypertension (HTN), CKD - Chronic Kidney Disease
Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health
This study tests whether adding CHW support to usual nutrition care helps adults with type 2 diabetes, hypertension, or chronic kidney disease manage their diet and health.
- Conditions
- Hypertension (HTN), CKD - Chronic Kidney Disease, Cardio-Renal Syndrome, Food Insecurity
- Trial name
- INTEGRATE-CHW (NCT07918508)
- Testing
- INTEGRATE-CHW, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Florida International University
Type2Diabetes, Hypertension
Digital Care for Holistic Health in Older Adults With Diabetes and Multimorbidity
The purpose of this study was to explore the effectiveness of the "Digital Care Community Common Good" program in improving disease control indicators, self-management abilities, depression, and quality of life among patients…
- Conditions
- Type2Diabetes, Hypertension, Dyslipidemia, CKD
- Trial name
- NCT07310849
- Testing
- Digital Care Community Common Good Program, Usual Care
- Where
- Taiwan
- Volunteers
- 169 people
- Sponsor
- Chang Gung University of Science and Technology
Carotid Plaque, Ischemic Stroke
Evaluation of Vulnerability of Carotid Plaques and Prediction of Cardio-Cerebrovascular Event Using Ultrasonic Imaging
This study included patients with carotid artery atherosclerotic plaques to conduct multimodal ultrasound examinations, aiming to establish a plaque vulnerability assessment model based on ultrasonic imaging indicators, clinical…
- Conditions
- Carotid Plaque, Ischemic Stroke, Cardiovascular Events
- Trial name
- NCT06473272
- Testing
- Cardiovascular and cerebrovascular diseases
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Systemic Lupus Erythematosus, Atherosclerosis Generalized
Effect of Anifrolumab on Arterial Inflammation in Systemic Lupus Erythematosus Study
People with systemic lupus erythematous (SLE) have an increased risk of premature atherosclerotic cardiovascular disease, which is believed to be caused by arterial inflammation.
- Trial name
- AISLE (NCT07913919)
- Testing
- 68-Gallium Dotatate, Anifrolumab
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Cambridge
Diabete Type 2, Cardio Vascular Disease
Role of Endothelial Progenitor Cells Dysregulation and Inflammation in the Pathophysiology of Cardiovascular Complications of Type 2 Diabetes
This study aims to isolate endothelial progenitor cells (EPCs) from participants with type 2 diabetes (T2D) and cardiovascular complications and to comprehensively characterize EPC dysfunction.
- Trial name
- NCT07556497
- Where
- Qatar
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Weill Cornell Medical College in Qatar
Acute Heart Failure, Congestive Heart Failure
The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure
Systemic venous congestion is the primary therapeutic target of intravenous loop diuretics in patients admitted for acute heart failure (AHF).
- Conditions
- Acute Heart Failure, Congestive Heart Failure, Intraabdominal Hypertension, Cardio-Renal Syndrome
- Trial name
- ABDOPOCUS-HF (NCT07008365)
- Testing
- Furosemide 20 Milligrams
- Where
- 2 sites in Spain
- Volunteers
- 168 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Hypertension, Diabetes Mellitus
Effectiveness of Laser Acupuncture in Improving Arterial Stiffness Among Patients With Cardiorenal Metabolic Syndrome
Background: Cardio-renal metabolic syndrome (CRMS) is a vicious cycle of cardiac, renal, and metabolic disease, representing a high-risk for atherosclerosis.
- Conditions
- Hypertension, Diabetes Mellitus, Chronic Kidney Disease, Cardio-Renal-Metabolic Syndrome
- Trial name
- NCT07543211
- Testing
- laser acupuncture
- Volunteers
- 35 people
- Sponsor
- National Yang Ming Chiao Tung University
Sleep Disorder (Disorder), Cardio Vascular Disease
Assessment of the Association Between Sleep Disorders Detected by a Simplified Questionnaire and Cardiovascular Diseases
The goal of this observational study is to validate a simplified questionnaire, adapted for routine clinical use, to quickly detect sleep disorders in patient during a cardiology consultation.
- Trial name
- CARDIOSOM (NCT07432828)
- Testing
- Online questionnaire
- Where
- 2 sites in France
- Volunteers
- 1,500 people
- Sponsor
- French Cardiology Society
Cardiorenal Syndrome, Heart Failure
Venous Ultrasound Guided Organ Decongestion in Patients Hospitalized with Acute Decompensated Heart Failure
The purpose of this study is to assess the feasibility, safety and effectiveness of VExUS guided organ decongestion compared to standard of care in patients hospitalized with acute decompensated heart failue (ADHF).
- Conditions
- Cardiorenal Syndrome, Heart Failure, Acute Kidney Injury, Acute Decompensated Heart Failure
- Trial name
- VExOUS-ADHF (NCT06714409)
- Testing
- VExUS guided decongestion
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Oslo University Hospital
Multiple Myeloma, Heart Disease Risk Factors
MM-CARE: Cardiovascular Risk Assessment in Adults With Multiple Myeloma
People with multiple myeloma may have health conditions or receive treatments that increase their risk of heart and blood-vessel problems.
- Trial name
- MM-CARE (NCT07783607)
- Testing
- Oncology-Embedded Cardiovascular Risk Assessment Pathway, Primary Care Provider-Directed Cardiovascular Risk Assessment Pathway
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Vermont Medical Center
Cardiogenic Shock, Pulmonary Edema Cardiac Cause
Hemodynamic Evaluation of Left Atrial Pressure in Relationship to Pulmonary Capillary Wedge Pressure in Cardio Thoracic Patients
Accurate hemodynamic monitoring is critical in cardiothoracic surgery, where left atrial pressure (LAP) serves as the gold standard for assessing left-sided cardiac filling pressures.
- Trial name
- HEART (NCT07163052)
- Volunteers
- 136 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cardio Vascular Disease, Cardiopulmonary Bypass
Perioperative Vericiguat in Patients Undergoing Cardiovascular Surgery
The purpose of this study is to evaluate the efficacy and safety of perioperative vericiguat in patients undergoing cardiovascular surgery.
- Trial name
- NCT07594509
- Testing
- Vericiguat, Standard of Care Group
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Nanjing Medical University
End Stage Renal Disease, Cardio-Renal Syndrome
Cardio-Renal Registry
Cardiovascular disease is the leading cause of morbidity and mortality among patients with chronic kidney disease (CKD). Even after adjustment for known cardiovascular risk factors, including diabetes and hypertension, mortality…
- Conditions
- End Stage Renal Disease, Cardio-Renal Syndrome, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- BHCRR (NCT06521801)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 60,000 people
- Sponsor
- Queen Mary University of London
Periodontal Disease (PD), Cardio Vascular Disease
PMPR and Chlorhexidine on Periodontal Disease and Vascular Function
Gum inflammation is called gingivitis. Gum disease, known as periodontal disease, is a long-term inflammation of the gums and bone around teeth, leading to tooth loss.
- Conditions
- Periodontal Disease (PD), Cardio Vascular Disease, Oral-Systemic Link, Vascular Dysfunction
- Trial name
- CHX-PMPR-PERIV (NCT07311512)
- Testing
- Chlorhexidine (0.2%) mouthwash
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Mahdi Mutahar
Cardiovascular Complication, Cardiovascular Insufficiency
Reporting, Evaluating, Preventing and Treating the Cardiotoxicity Induced by Anticancer Drugs During a Specific Cardio-oncology Consult and Follow up in Routine Care
Several Drugs used in routine care in oncology induce rare but often severe or fatal cardiovascular or metabolic side effects. This study will investigate, evaluate, report and treat the cardiovascular side effects of anticancer…
- Conditions
- Cardiovascular Complication, Cardiovascular Insufficiency, Cardiac Complication, Oncologic Complications
- Trial name
- NEOCARDIO (NCT03882580)
- Testing
- Anti-Cancer Agents
- Where
- 3 sites in France
- Volunteers
- 5,000 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Dyslipidemia, Hypercholesterolemia, Hypertriglyceridemia, Stroke (CVA) or TIA
Effectiveness and Tolerability of a Treat-to-Target Versus Fixed-Dose Statin Strategy in Patients With Atherosclerotic Cardiovascular Disease
To compare the efficacy of fixed-dose versus treat-to-target statin regimens in achieving the predefined LDL-C target at 12 weeks in patients with established ASCVD.
- Conditions
- Dyslipidemia, Hypercholesterolemia, Hypertriglyceridemia, Stroke (CVA) or TIA, Cardio Vascular Disease
- Trial name
- NCT07909915
- Testing
- Dose adjustment of statins, no dose adjustment
- Where
- Pakistan
- Volunteers
- 178 people
- Sponsor
- Rehman Medical Institute - RMI