Clinical trials: Cardiometabolic Conditions
Overweight and Obesity, Metabolic Syndrome
Whole-body Electromyostimulation Versus Conventional Low-volume Strength Training in Overweight Individuals
The main purpose of this study is to compare the effects of whole-body electromyostimulation versus a conventional low-volume strength-training program, each combined with an individualized, weight-reducing diet, on the…
- Trial name
- EKAM (NCT03306056)
- Testing
- Control, Standard Strength Training, Low-volume Strength Training
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Effects of Turkish Coffee Consumption on Cardiovascular Markers and Sleep in Healthy Women, Cardiometabolic Health Markers, Appetite-regulating Hormones, Inflammation, and Sleep Quality in Healthy Women
Effects Of Turkish Coffee Consumption On Cardiovascular Markers And Sleep In Healthy Women
This randomized controlled trial aims to evaluate the short-term effects of daily unfiltered Turkish coffee consumption on cardiovascular parameters, appetite-regulating hormones, glucose metabolism, inflammatory markers, and…
- Trial name
- TURCOFFEE (NCT07133373)
- Testing
- Turkish Coffee (unfiltered, boiled)
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Petra
Overweight and Obesity, Metabolic Syndrome
Effects of Low-volume Aerobic Interval Training in Overweight Individuals at Increased Cardiometabolic Risk
The main purpose of this study is to compare the impact of aerobic interval training intensity on exercise adherence and changes in cardiorespiratory fitness, cardiometabolic risk profile, body composition, inflammatory markers…
- Trial name
- BELITA (NCT03306069)
- Testing
- Control, HIIT, MIIT-HR
- Where
- Germany
- Volunteers
- 154 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Obesity
Impact of Pulse-enriched Foods on Cognitive Function and Cardiometabolic Health in Obese Adults
The Canadian population, as is the case in most developed countries, is ageing and becoming increasingly overweight and/or obese.
- Trial name
- PULSA-2011 (NCT01495832)
- Testing
- Pulse Group, Control Group
- Where
- 2 sites in Australia, Canada
- Volunteers
- 150 people
- Sponsor
- University of Manitoba
Obesity, Physical Inactivity
Effects of Short Isokinetic Eccentric Resistance Training on Neuromuscular Induced Adaptations
The study compares the impact of isokinetic resistance training (RT) -induced neuromuscular adaptation following an 8-week short ECC ISO RT and CON ISO RT among obese, untrained women. The main question it aims to answer is: 1.
- Trial name
- NCT07407621
- Testing
- ECC ISO, CON ISO
- Where
- Malaysia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Occupational Stress, Gender Related Stress
Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women
The goal of this hybrid Type 1 effectiveness-implementation trial is to test the extent to which a peer support and community resource navigation intervention improves psychological well-being, addresses non-biologic drivers of…
- Conditions
- Occupational Stress, Gender Related Stress, Social Isolation, Hypertension
- Trial name
- NCT07111026
- Testing
- Sisters for Heart Health, Basic intervention
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Emory University
Diabetes, Prediabetes
Meta-Analyses of the Effect of Plant Protein Versus Animal Protein on Cardiometabolic Risk
Vegetarian diets have been associated with a reduced risk of preventable diseases such as type 2 diabetes and cardiovascular disease. These effects may be mediated through direct or indirect pathways.
- Conditions
- Diabetes, Prediabetes, Metabolic Syndrome, Dysglycemia
- Trial name
- NCT02037321
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Time Restricted Eating, Obesity
Effects of Time-restricted Eating and Aerobic Exercise Training in Women With Overweight and Obesity
Time-restricted eating (TRE) is a dietary approach that aims to increase fasting time and decrease the eating window. Promising TRE effects on weight loss and improvements in some cardiometabolic risk factors have been reported…
- Conditions
- Time Restricted Eating, Obesity, Intermittent Fasting, Overweight and Obesity
- Trial name
- NCT06302231
- Testing
- Dietary and Exercise Approaches, Dietary Approach
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Cirrhotic Cardiomyopathy, Empagliflozin
DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis
1. This proposed double-blind placebo controlled randomized controlled trial incorporates recent advances in management of heart failure and portal hypertension using the SGLT-2 inhibitor i.e. EMPAGLIFLOZIN.
- Conditions
- Cirrhotic Cardiomyopathy, Empagliflozin, Cardiometabolic Risk Factors, Cirrhosis
- Trial name
- DICE (NCT07322237)
- Testing
- Empagliflozin + Carvedilol, Carvedilol
- Where
- India
- Volunteers
- 400 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cardiovascular Risk Markers, Postprandial Metabolism
Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults
The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk…
- Conditions
- Cardiovascular Risk Markers, Postprandial Metabolism, Exercise Physiology, Substrate Oxidation
- Trial name
- NCT07229963
- Testing
- Aerobic Exercise Intervention, Sprint Exercise Intervention, Sedentary Behaviour Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Insulin Resistance, Obesity
Potato Research for Enhancing Metabolic Outcomes
The potato is a nutritious food that comprises approximately 30% of total vegetable intake in the United States (US). Consumption of pulses in the US is low but its contribution to health is frequently promoted.
- Trial name
- PREMO (NCT04203238)
- Testing
- Reduced Meat High Potato Diet, Reduced Meat High Pulses Diet
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Pennington Biomedical Research Center
Prediabetes, Hypercholesterolemia
Effect of Simvastatin and Ezetimibe on Lipid and Inflammation
Ezetimibe specifically blocks the absorption of dietary and biliary cholesterol and plant sterols. Synergism of ezetimibe-statin therapy on LDL-cholesterol has been demonstrated, but data concerning the pleiotropic effects of…
- Conditions
- Prediabetes, Hypercholesterolemia, Inflammation, Cardiovascular Risk
- Trial name
- NCT01103648
- Testing
- Simvastatin, Ezetimibe, Combination Simvastatin plus Ezetimibe
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of São Paulo
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Obesity
Modified Intermittent Eating on Weight Loss (INTEREST-3 Trial)
Calorie restriction (CR) is the most important treatment for weighting loss. In recent years, two novel types of intermittent fasting recently have gained more attention: the 5:2 diet and time-restricted eating (TRE).
- Trial name
- INTEREST-3 (NCT06302803)
- Testing
- Intermittent fasting plus time-restricted eating, Calorie restriction
- Where
- China
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Hypertension, Undiagnosed Diseases
Project 1: ACHIEVE- HTN
This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health Inequities by Early PreVEntion in the GREAT LakEs Region) Center (IRB 100221MP2A), the purpose of which is to reduce cardiometabolic health…
- Trial name
- NCT05295758
- Testing
- PAL2
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Time Restricted Feeding, Exercise
Time-Restricted Eating, Exercise and Cardiometabolic Health in Obesity
In Spain, overweight and obesity prevalence is reaching 70% in men and 50% in women. Excess of triglycerides are usually stored in the subcutaneous adipose tissue (SAT), until a point where SAT is unable to expand further.
- Conditions
- Time Restricted Feeding, Exercise, Hepatic Steatosis, Cardiometabolic Syndrome
- Trial name
- TEMPUS (NCT05897073)
- Testing
- Time-restricted eating intervention, Exercise intervention, Time-restricted eating plus exercise intervention
- Where
- 2 sites in Spain
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Abdominal Obesity
INNUPREC (Nutrigenetic Intervention for the Prevention of Cardiovascular Disease)
Background: Abdominal obesity (AO) is a multifactorial disease that affects 81.6% of the Mexican population; it is characterized by the excessive accumulation of adipose tissue in abdominal region.
- Trial name
- INNUPREC (NCT06847243)
- Testing
- Nutrigenetic diet according the genetic test, Control intervention group
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Time Restricted Feeding, Obesity, Abdominal
Efficacy and Feasibility of Time-restricted Eating on Cardiometabolic Health in Adults With Overweight/Obesity
In Spain, obesity epidemic is one of the leading contributors of chronic disease and disability. Obesity is associated with higher morbidity and all-cause mortality risk especially when fat is stored in the abdominal area (i.e.…
- Conditions
- Time Restricted Feeding, Obesity, Abdominal, Cardiometabolic Syndrome
- Trial name
- EXTREME (NCT05310721)
- Testing
- Early time-restricted eating, Late time-restricted eating, Self-selected time-restricted eating
- Where
- 2 sites in Spain
- Volunteers
- 197 people
- Sponsor
- Universidad de Granada
Cardiometabolic Syndrome, Physical Inactivity
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8…
- Conditions
- Cardiometabolic Syndrome, Physical Inactivity, Hypertension, Type 2 Diabetes
- Trial name
- NCT06055036
- Testing
- Black Impact Intervention
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- Ohio State University
Fasting Conditions, Metabolic Health
Effects of the Buchinger Wilhelmi Fasting Program and Exercise on Physical Fitness and Sleep Quality
Type of Study: Clinical Trial Goal: The goal of this clinical trial is to investigate whether combining the Buchinger Wilhelmi prolonged fasting program with a structured exercise program can improve physical fitness, body…
- Trial name
- FASTEX (NCT07847658)
- Testing
- Buchinger Wilhelmi prolonged fasting, Online exercise program, Supervised exercise program during prolonged fasting
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria