Clinical trials: Cardiometabolic Conditions
Metabolic Disease, Obesity
Adiposity, Cardiometabolic and Neurocognitive Health Among Ethnic Groups: a Feasibility and Pilot Study
The goal of this pilot and feasibility study is to is to test the feasibility of conducting a cross-sectional study on adiposity and cardiometabolic and neurocognitive risk factors at Kings College Hospital NHS Foundation Trust…
- Conditions
- Metabolic Disease, Obesity, Hepatic Steato-Fibrosis, Cardiovascular Diseases
- Trial name
- ACNH (NCT06435611)
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- King's College Hospital NHS Trust
Cardiometabolic Syndrome, Obesity
Impact of Yo-Yo Sleep on Cardiometabolic Health
The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance…
- Trial name
- NCT05880758
- Testing
- Intermittent Short Sleep (ISS), Social Jetlag (SJL), Sustained Adequate Sleep (SAS)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Columbia University
Pulmonary Disease, Chronic Obstructive, Muscular Atrophy
Nutritional Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Muscle Atrophy
To study in clinically stable Chronic Obstructive Pulmonary Disease (COPD) patients with muscle atrophy: 1. The short-term effects of 4 months exercise training including nutritional supplementation versus exercise training alone…
- Trial name
- NUTRAIN (NCT01344135)
- Testing
- Dietary supplementation, Nutritional counselling, Feedback on physical activity level
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- Maastricht University Medical Center
Type 2 Diabetes Mellitus, Cardiometabolic Conditions
Mi Puente: My Bridge to Better Cardiometabolic Health and Well-Being
Mi Puente (or "My Bridge") is a culturally-tailored, interdisciplinary approach designed to support at-risk Hispanic patients and their caregivers pre- and post-hospital discharge as they navigate the multi-level barriers that…
- Conditions
- Type 2 Diabetes Mellitus, Cardiometabolic Conditions, Behavioral Health Concerns
- Trial name
- Mi Puente (NCT02723019)
- Testing
- Volunteer Peer Mentor+Behavioral Health Nurse
- Where
- United States
- Volunteers
- 536 people
- Sponsor
- Scripps Whittier Diabetes Institute
Cardiovascular Diseases, Adiposity
The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health
Recently a dietary recommendation of 400 - 600 mg/ day has been proposed for the reduced risk of developing cardiovascular disease.
- Conditions
- Cardiovascular Diseases, Adiposity, Cardiometabolic Syndrome
- Trial name
- NCT06476795
- Testing
- Chardonnay Marc
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Type 2 Diabetes Mellitus
Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study
The purpose of the ROSITEL study is to assess the effects of rosiglitazone, as compared to standard oral therapies for diabetes (metformin/sulfonylurea), on inflammatory markers and adipokine levels in diabetic patients using an…
- Trial name
- NCT00486187
- Testing
- rosiglitazone, metformin or sulfonylurea
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- Dr. Milan Gupta
Overweight, Obesity
Aquatic and Land Physical Training Effects on Cardiometabolic Risk Factors in Adolescents With Overweight and Obesity
Objective: To compare the results of two types of low-impact exercise training, in and out of the water, with the control group, regarding cardiometabolic risk factors in overweight adolescents; and to investigate the changes…
- Trial name
- NCT02309034
- Testing
- Jump exercise, Aquatic exercise, Nutritional guidance
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cardiometabolic Risk Factors, Cardiometabolic Conditions
Asian-Mediterranean Diet and Women's Health
Given the escalating high burdens of overeight and obesity, and related commobidies in Asia, Asian women with overweight/obesity is an important group for targeted intervention in promoting health and wellbeing.
- Conditions
- Cardiometabolic Risk Factors, Cardiometabolic Conditions, Women Health
- Trial name
- A+ MEAL (NCT06825936)
- Testing
- Diet intervention, Control
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Global Centre for Asian Women's Health
Obesity & Overweight, Cardiometabolic Risk Factors
Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight
The purpose of this research study is to pilot test five different, group based and remotely delivered programs designed to support healthy eating and regular physical activity.
- Trial name
- NEW PATH (NCT07363616)
- Testing
- Mediterranean eating style, Physical activity, Mindful Eating
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Cardiovascular Diseases
Effects of Chronic Energy Drink Consumption on Cardiometabolic Endpoints
Many people use energy drinks (EDs) regularly, but the overall health concerns are still unknown. There are many energy drink products that contain a mixture of caffeine and other energy-boosting ingredients and supplements which…
- Trial name
- NCT03840863
- Testing
- Commercially-Available Energy Drink
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of the Pacific
Overweight and Obesity, Prediabetes
Effects of Biofunctional Orange Juice on Cardiometabolic Risk Markers
The effects of orange juice enriched with vitamin D3 and encapsulated probiotics (Lacticaseibacillus casei Shirota and Lacticaseibacillus rhamnosus GG) compared to conventional orange juice on several cardiometabolic and…
- Conditions
- Overweight and Obesity, Prediabetes, Hypertension, Dyslipidemias
- Trial name
- NCT06114576
- Testing
- Orange juice enriched with vitamin D3 and encapsulated probiotics, Conventional orange juice
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Agricultural University of Athens
Dyslipidemias, Obesity
Metabolic Optimization Through Diet/Lifestyle Improvements For Youth
The overarching goal of this study is to evaluate plasma ceramides (Cers) as early nutrition-sensitive biomarkers of metabolic health.
- Trial name
- MODIFY (NCT04270084)
- Testing
- Alive-Family
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Children's National Research Institute
Obesity, Adolescent, Metabolic Syndrome
High-intensity Small-sided Soccer Games for Cardiometabolic Health in Adolescents With Metabolic Dysfunction
Pediatric obesity is considered one of the most important public health problems worldwide due to its high prevalence and associated comorbidities.
- Trial name
- NCT06377137
- Testing
- Small-sided soccer games groups (SSSG), Traditional soccer training groups (TSG)
- Where
- Portugal
- Volunteers
- 51 people
- Sponsor
- Universidade do Porto
Obesity & Overweight, Cardiometabolic Conditions
Incretin-based Therapies, Nutrition, and Physical Activity
The goal of this clinical trial is to evaluate whether combining a six-month structured lifestyle intervention (physical activity and nutrition) with incretin-based weight-loss medication improves preservation of muscle mass and…
- Trial name
- HARMONY (NCT07409831)
- Testing
- Intervention, Incretin-Based Treatment
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Laval University
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Spinal Cord Injuries
Diet Composition and Cardiometabolic Risk Reduction in Adults With SCI
The purpose of this study is to examine the effectiveness of a low carbohydrate diet on increasing dietary adherence and improving cardiometabolic risk factors among adults with spinal cord injury (SCI).
- Conditions
- Obesity, Spinal Cord Injuries, Diabetes
- Trial name
- NCT02630524
- Testing
- eHealth Behavioral Lifestyle Intervention Device: Telecoach
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Cardiometabolic Health, Pregnancy Related
Cardiometabolic Health in First Time Pregnancy
Women who experience placental complications (syndromes) during pregnancy, such as pre-eclampsia (high blood pressure and kidney problems), gestational hypertension (high blood pressure during pregnancy) and fetal growth…
- Conditions
- Cardiometabolic Health, Pregnancy Related, Diabetes, Placental; Syndrome, Dysfunction
- Trial name
- POPPY (NCT05856318)
- Where
- 7 sites in United Kingdom
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Focus of Study: Work Conditions
Evaluating the Health Benefits of Workplace Policies and Practices - Phase II
Although the prevalence of "family-friendly" policies in US workplaces has increased dramatically, few have been studied using scientifically sound designs.
- Trial name
- WFHS (NCT02050204)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 2,753 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Obesity and Overweight
Intermittent Carbohydrate Restriction in Cardiometabolic Health
Metabolic conditions, such as heart disease, type 2 diabetes, and metabolic syndrome, are among the leading causes of disability and mortality worldwide.
- Trial name
- NCT06684834
- Testing
- 5:2 carbohydrate restriction, Early time-restricted carbohydrate intake
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bath
Diabetes (DM), Hypertension
Multimodal Cardiovascular Magnetic Resonance Imaging for Cardiometabolic Pre-HF and HFpEF
This is an observational study aiming to characterize the pathophysiological features and clinical significance of cardiometabolic early-stage heart failure using advanced multimodal cardiovascular magnetic resonance (CMR)…
- Conditions
- Diabetes (DM), Hypertension, Heart Failure, Obesity & Overweight
- Trial name
- NCT07336316
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital