Clinical trials: Cardiometabolic Conditions
Obesity, Hypertension
Exercise Effects on Cardiometabolic Health and Sestrin-2 in Hypertensive Obese Women
Obesity is a chronic and complex disease characterized by excessive fat accumulation that adversely affects health and quality of life.
- Trial name
- SES-EX (NCT07370363)
- Testing
- Moderate-Intensity Continuous Exercise, Brisk Interval Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Havva Talay Çalış
Overweight, Obesity
Effects of Intermittent Caloric Restriction in Youth With Cardiometabolic Risk
This is a randomized controlled pilot study to evaluate the effects of intermittent caloric restriction compared with low carbohydrate diet in youth with cardiometabolic risk.
- Conditions
- Overweight, Obesity, Cardiometabolic Risk
- Trial name
- NCT04011995
- Testing
- Intermittent caloric restriction, Low carbohydrate diet, Health education on reducing the cardiometabolic risk
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Children's Hospital of Fudan University
Cardiovascular Diseases, Obesity
The Weight of Cardiovascular Disease
The purpose of this study is to evaluate the impact of a cardiometabolic clinic on percent body weight loss, body mass index (BMI), and visceral adiposity distribution in obese adults with cardiovascular disease (CVD) at 12…
- Trial name
- NCT06053645
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Mayo Clinic
Nutrition, Healthy, Dyslipidemia
Cardiometabolic Effects of the Recommended Daily Pecan Intake Dose
Cardiovascular disease risk factors, including higher BMIs and poor cholesterol profiles, are on the rise and contribute to the United States' growing disease burden.
- Conditions
- Nutrition, Healthy, Dyslipidemia, Overweight and Obesity
- Trial name
- NCT07696403
- Testing
- Pecan, Control
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Overweight, Obesity
Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease
Since uncontrolled observational studies first linked fructose to the epidemic of obesity almost a decade ago, it has become a focus of intense concern regarding its role in the obesity epidemic and increasing burden of…
- Conditions
- Overweight, Obesity, Dyslipidemia, Hyperlipidemia
- Trial name
- NCT01608620
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Weight Loss, Gut Microbiome
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
This study will systematically quantify the effects of protein pacing and intermittent fasting (P-IF) on total and regional (abdominal) body composition (lean mass and fat mass), blood glucose and lipids, and anti-aging…
- Conditions
- Weight Loss, Gut Microbiome, Anti-Aging
- Trial name
- NCT04327141
- Testing
- P-IF, HH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Overweight and Obesity
Efficacy of Telenutrition for the Treatment of Overweight Patients With Obesity and/or High Cardiometabolic Risk
The OBE-COACH program is an automated online nutritional coaching service that was evaluated in its first version (MXS-CARE program) in a clinical trial coordinated by our team, in type 2 diabetic patients with abdominal obesity.
- Trial name
- TOOLBAR (NCT04941651)
- Testing
- OBE-COACH program, Connected devices, Connected Activity Tracer
- Where
- France
- Volunteers
- 346 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Traumatic Brain Injury, Brain Injuries, Traumatic
Scale-Up Evaluation Trial of the Diabetes Prevention Program to Improve Obesity and Cardiometabolic Health After Traumatic Brain Injury
The Investigators have proposed targeted efforts to address the feasibility, effectiveness, fidelity, and evaluation of the GLB-TBI Evidence Based Intervention (EBI) in a real world setting at a CDC-recognized site
- Conditions
- Traumatic Brain Injury, Brain Injuries, Traumatic, Brain Injury, Chronic
- Trial name
- GLB Scale-Up (NCT07648901)
- Testing
- Group Lifestyle Balance for People with TBI (GLB-TBI)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Baylor Research Institute
Childhood Obesity
Translational Investigation of Growth and Everyday Routines in Kids
The purpose of this study is to determine the effect of severe obesity on physical activity, sedentary behavior and cardiometabolic risk factors during childhood and adolescence and whether these associations are modified by…
- Trial name
- TIGER Kids (NCT02784509)
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
Using Grassroots Wellness Coaching to Enhance Reach and Sustainability of Behavioral Weight Management
African American adults that live in economically disadvantaged areas are at an increased risk for obesity and cardiometabolic disease.
- Trial name
- NCT05544708
- Testing
- Wellness Engagement Intervention
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Cardiovascular Risk Factor
SEMEiotic Oriented Technology for Individual's CardiOmetabolic Risk Self- assessmeNt and Self-monitoring
Cardio-metabolic risk factors include obesity, physical inactivity, smoke, alcohol abuse, high blood lipids or sugar and arterial hypertension.
- Trial name
- SEMEOTICONS (NCT02818504)
- Testing
- Wize Mirror
- Where
- 3 sites in France, Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istituto di Fisiologia Clinica CNR
Down Syndrome, Trisomy 21
Down Syndrome Metabolic Health Study
The purpose of this research study is to determine which measures best capture cardiovascular disease (CVD) risk and type 2 diabetes (T2DM) risk in children and adolescents with Down syndrome (DS).
- Trial name
- NCT01821300
- Where
- 2 sites in United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Cardiometabolic Syndrome, Type 2 Diabetes
Circadian Intervention to Improve Cardiometabolic Health
The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD).
- Conditions
- Cardiometabolic Syndrome, Type 2 Diabetes, Sleep, Time Restricted Feeding
- Trial name
- TOCS (NCT05943626)
- Testing
- Circadian Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Utah
Overweight
Cardiometabolic Effects of Combined Aerobic Exercise and Non-Exercise Physical Activity
The goal of this clinical trial is to investigate whether increasing non-exercise physical activity combined with aerobic exercise in overweight young women is superior to performing aerobic exercise alone in terms of some…
- Trial name
- NCT06270810
- Testing
- Aerobic Exercise, Increasing non-Exercise Physical Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Inflammation, Macrophage Infiltration
Effectiveness of Sitagliptin for HIV Insulin Resistance and Inflammation
People living with human immunodeficiency virus infection (HIV) have 2-4fold greater risk for developing diabetes and heart disease than the general population.
- Conditions
- Inflammation, Macrophage Infiltration, Cardiovascular Disease
- Trial name
- NCT01552694
- Testing
- Sitagliptin
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Washington University School of Medicine
Psychological Distress
Impact of an Amino Acid Composition With Micronutrients on Wellbeing of Patients With Chronic Exhaustion Conditions
Chronic psychological distress can lead to chronic exhaustion conditions, such as burnout. These conditions are associated with a deficiency of specific amino acids and micronutrients that cause endocrine-cardiometabolic…
- Trial name
- BOT-01 (NCT02997137)
- Testing
- BOT-01
- Where
- Germany
- Volunteers
- 74 people
- Sponsor
- Doris Meister
Cardiovascular Risk, Hypercholerolemia
Study of the Effects of Yerba Mate on Cardiometabolic Health
The goal of this clinical trial is to learn if consuming a beverage prepared with yerba mate leaves helps to improve blood lipid levels in persons at high cardiovascular risk.
- Trial name
- INFU-SALUD (NCT06729905)
- Testing
- Yerba mate tea, Control drink
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Preeclampsia, Postpartum Period
The PreEclampsia Postpartum Prevention Trial
The goal of this clinical trial is to learn if a postpartum bundle intervention can improve cardiometabolic health and lifestyle-related factors in women who have had preeclampsia during their first pregnancy.
- Conditions
- Preeclampsia, Postpartum Period, Hypertension, Cardiovascular Diseases
- Trial name
- PEPP (NCT07199283)
- Testing
- Bundle Intervention
- Where
- 2 sites in Sweden
- Volunteers
- 356 people
- Sponsor
- Karolinska Institutet
Breast Cancer Risk, Cardiovascular Disease Risk
The RISC Registry--Risk Informed Screening Registry
Chronic diseases such as heart disease, cancer, and diabetes are the leading causes of death and disability in the United States. Six in ten adults have one chronic disease; 4 in 10 have two or more.
- Conditions
- Breast Cancer Risk, Cardiovascular Disease Risk, Cardiometabolic Risk, Diabetes
- Trial name
- RISC (NCT05848856)
- Testing
- Breast Cancer, Cardiometabolic, Cardiovascular Risk Screening and Follow up
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Precision Health Equity Initiative
Overweight and Obesity, PreDiabetes
Effects of Yogurt With Spirulina on Cardiometabolic Risk Markers
The effects of yogurt with spirulina consumption compared to conventional yogurt (without spirulina) on several cardiometabolic and anthropometric parameters in individuals at risk of cardiovascular disease
- Conditions
- Overweight and Obesity, PreDiabetes, Hypertension, Dyslipidemias
- Trial name
- NCT06114563
- Testing
- Spirulina yogurt, Conventional yogurt
- Where
- Greece
- Volunteers
- 64 people
- Sponsor
- Agricultural University of Athens