Clinical trials: Cardiometabolic Conditions
Physical Activity, Sedentary Behavior
Teen Mom Study Feasibility Trial
The proposed multicomponent digital health intervention has the potential to significantly impact the trajectory of maternal health in a rural, pregnant, Black adolescent population with the highest risks for cardiometabolic…
- Conditions
- Physical Activity, Sedentary Behavior, Gestational Weight Gain, Social Determinants of Health
- Trial name
- NCT05843903
- Testing
- #BabyLetsMove
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Overweight , Obesity
A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)
The purpose of this study is to learn whether following an online weight loss program with specific dietary and exercise goals (the 30-30-30 plan) can help improve weight loss and other markers of health when compared to an…
- Trial name
- NCT07789769
- Testing
- 30-30-30 PFE Intervention, Standard
- Where
- 3 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Spinal Cord Injuries, Obesity
Telenutrition for Individuals With SCI
This study will provide nutrition counseling via FaceTime on an iPad to persons with traumatic spinal cord injury (SCI) who are overweight or obese and are at least one-year post-injury.
- Conditions
- Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
- Trial name
- NCT05468437
- Testing
- Telenutrition
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Santa Clara Valley Health & Hospital System
Diabetes, Obesity
Implementation of a Cardiometabolic Disease Staging System in Primary Care
The aim of this study is to develop a clinical decision support system (CDSS) that incorporates obesity management guidelines and treatment options for use by physicians and, potentially, patients based on a cardiometabolic…
- Conditions
- Diabetes, Obesity, Overweight
- Trial name
- NCT04922294
- Testing
- Clinical decision support system
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity, Cardiovascular Risk Factor
Healthy Nordic Foods to Prevent Cardiometabolic Risk in Obese Subjects
This project will examine whether long-term consumption of healthy Nordic foods can maintain a healthy weight also after weight loss, and decrease abdominal fat accumulation and cardiometabolic risk.
- Conditions
- Obesity, Cardiovascular Risk Factor, Diet Modification
- Trial name
- NCT03102853
- Testing
- Nordic diet, Control diet
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lund University
Metabolic Syndrome, Obesity
Virtual Enhanced Lifestyle for Metabolic Syndrome (ELM) Proof-of-Concept Study
This is a proof-of-concept study of a virtual version of a lifestyle intervention aimed at reducing cardiometabolic risk in patients with the Metabolic Syndrome (MetS).
- Trial name
- NCT04637477
- Testing
- Virtual ELM
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cardiovascular Risk Factor, Cardiovascular Diseases
Umbrella Review of the DASH Dietary Pattern and Cardiometabolic Risk
The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding the Dietary Approaches to Stop Hypertension (DASH) diet, a dietary pattern that emphasizes fruits and…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Coronary Heart Disease, Stroke
- Trial name
- NCT03542370
- Testing
- DASH dietary pattern
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Diabetes Mellitus, Diabetes Mellitus, Type 2
A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program
A pilot study titled "A Virtual Cardiometabolic Health Program for African Immigrants (The Afro-DPP Program) will be conducted to address the cardiometabolic of community-dwelling African immigrants who have multiple…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 2, PreDiabetes, Hypertension
- Trial name
- NCT05144737
- Testing
- The Diabetes Prevention Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Cardiometabolic Diseases, Obesity
Prenatal Programming of Childhood Obesity and Cardio Metabolic Disorders
This is a prospective 11-17 -years follow-up of two existing pregnancy cohort (PREDO) and prevention (RADIEL) studies. The main objective is to investigate the associations between maternal overweight, obesity, hypertensive…
- Trial name
- NCT05223530
- Where
- Finland
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Healthy, Normal Weight
Response of Gut Microbiota and Cardiometabolic Biomarkers to Consumption of Walnuts
The researchers will investigate blood and fecal responses in qualified study participants after eating walnuts for 4 weeks compared to not eating walnuts for 4 weeks.
- Conditions
- Healthy, Normal Weight, Overweight, Obese
- Trial name
- NCT04307628
- Testing
- Walnut, Nut-Free
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Physical Inactivity, Cardiovascular Risk Factor
The Clinical Referral to Activity Study
The main aim of this effort is to test a physical activity intervention, for adult clinical care patients at risk of developing cardiovascular disease.
- Conditions
- Physical Inactivity, Cardiovascular Risk Factor, Obesity, Blood Pressure
- Trial name
- NCT04743856
- Testing
- ActiveGOALSv2, PAT
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity, Prehypertension
Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults
The proposed 6-month pilot Sequential Multiple Assignment Randomize Trial (SMART) has two aims. The first and primary aim is to determine the feasibility of conducting a full-scale SMART to compare weight-focused (i.e., weight…
- Conditions
- Obesity, Prehypertension, Hypertension, PreDiabetes
- Trial name
- WISE Health (NCT06284681)
- Testing
- Weight-focused health coaching, Weight-neutral health coaching, Intensify lifestyle approach
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Alabama at Birmingham
Lifestyle Factors, Overweight and Obesity
Effect of Sleep Extension on Ceramides in People With Overweight and Obesity
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity.
- Conditions
- Lifestyle Factors, Overweight and Obesity, Insulin Sensitivity, Eating Habit
- Trial name
- NCT06180837
- Testing
- Sleep Extension Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Utah
PreDiabetes, Obesity
WorkWell: Work-based Activity and Metabolic Health
This study will test whether a range of pre-clinical cardiometabolic biomarkers can be improved via regular intervals of standing and light-intensity physical activity in real-world office environments.
- Trial name
- NCT04269070
- Testing
- Standing condition, Light physical activity (LPA) condition, Usual behavior condition
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Obesity
Effect of Oral Supplementation With Probiotics
Effect of oral supplementation with probiotics on cardiometabolic risk factors, microflora and intestinal epithelial permeability, mineral content and lifestyle in obese women with postmenopausal metabolic syndrome: double-blind…
- Trial name
- NCT03100162
- Testing
- Probiotic
- Where
- Poland
- Volunteers
- 81 people
- Sponsor
- Poznan University of Medical Sciences
Acute Lymphoblastic Leukemia, Obesity
Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity
This is a 28-week, single-arm, open-label phase II clinical trial evaluating the combination of Tirzepatide and remote, supervised, tailored resistance exercise training to achieve weight loss in adult survivors of childhood…
- Trial name
- NCT07228741
- Testing
- Tirzepatide, Resistance Exercise, Lifestyle Counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Jude Children's Research Hospital
Type 2 Diabetes Mellitus, Obesity
Vitamin D Status and Lipid Profile in Obese Adults With Type 2 Diabetes
This prospective, single-center, cross-sectional observational study aims to evaluate the association between serum 25-hydroxyvitamin D concentrations and lipid profile parameters among adults with obesity and established type 2…
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Dyslipidemia, Vitamin D Deficiency
- Trial name
- VILD-T2D (NCT07729553)
- Volunteers
- 150 people
- Sponsor
- Sinai University
Arterial Stiffness, Blood Pressure
Prebiotic Effects of California Grapes on Gut Health and Cardiometabolic Health in Overweight Men and Women
The goal of this clinical trial is to assess the impact of table grape consumption on gut microbiome, intestinal permeability, systemic inflammation, and vascular function in healthy overweight men and women aged 45-70 years.
- Conditions
- Arterial Stiffness, Blood Pressure, Dysbiosis, Inflammation
- Trial name
- CALGRAM (NCT06544954)
- Testing
- Freeze-dried grape powder
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Schizophrenia, Schizoaffective Disorder
Lifestyle Intervention for Young Adults With Serious Mental Illness
This is a four year project evaluating the effectiveness of a group-based lifestyle intervention (PeerFIT) supported by mobile health (mHealth) technology and social media compared to Basic Education in fitness and nutrition…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT02815813
- Testing
- PeerFIT, BEAT
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Heart Diseases, Stroke
The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women
This study will test whether a culturally-tailored nutrition and exercise intervention designed for African-American women will lead to sustained improvements in exercise and healthy eating through improvements in self-management…
- Conditions
- Heart Diseases, Stroke, Pre-diabetes, Hypertension
- Trial name
- NCT04705779
- Testing
- HARMONY, Nutrition and Exercise Education (NEEW)
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of North Carolina, Chapel Hill