Clinical trials: Cardiometabolic Factors
Obesity, Metabolic Syndrome
Fish or Nuts? Dietary Effects on Cardiometabolic Risk Factors and Persistent Organic Pollutants
Obesity represents one of the most important public health challenges for the societies. Although excess energy intake and physical inactivity are major causes of obesity and cardiometabolic disorders, emerging evidence has…
- Conditions
- Obesity, Metabolic Syndrome, Diabetes
- Trial name
- NCT02589756
- Testing
- The fatty fish group, The nut group, The control group
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Cardiometabolic Risk Factors, Cognitive Function
The Effect of Tart Cherry (Prunus Cerasus) Concentrate on Physiological and Cognitive Function
A randomized, double blind, counterbalanced, placebo controlled independent groups design to determine the effects of 3 month supplementation with tart cherry concentrate on indices of cardiometabolic health, exercise capacity…
- Conditions
- Cardiometabolic Risk Factors, Cognitive Function, Exercise Capacity
- Trial name
- NCT04021342
- Testing
- Montmorency tart cherry concentrate
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Bariatric Patients
Quality of Life and Cardiometabolic Risk Factors in Patients After Debanding
Follow up of debanding patients
- Trial name
- NCT00497627
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Metabolic Syndrome, Diabete Type 2
Metformin Versus Vildagliptin in Reducing Risk of Metabolic Syndrome Complications Progression
Several crosssectional and prospective studies have shown that metabolic syndrome and its related components are associated with both prevalent and incident CKD .
- Conditions
- Metabolic Syndrome, Diabete Type 2, Kidney Insufficiency
- Trial name
- NCT04485845
- Testing
- Vildagliptin, Captopril Tablets, MetFORMIN 500 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Cairo University
Hypertension
Study of the Impact of Low Fat Dairy and High Fat Dairy Consumption on Daytime Ambulatory Blood Pressure
Market trends depicted by Agriculture and Agri-Food Canada suggest stagnation in cheese consumption, with potentially important impact on this key industry in Canada.
- Trial name
- GABA2 (NCT02763930)
- Testing
- Control diet, Milk diet, GABA-rich cheese diet
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
Bipolar Youth Treated With Second-generation Antipsychotics
SGA-induced Metabolic Syndrome in Bipolar Youth
The investigators tested the hypothesis that long-chain omega-3 (LCn-3) fatty acid supplementation will attenuate the adverse cardiometabolic effects of second-generation antipsychotics exposure in first-episode adolescent manic…
- Trial name
- NCT01858948
- Testing
- Omega, Quetiapine fumarate
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Cincinnati
Hyperuricemia, Diet, Healthy
Vegan Diet, Amla Fruits and Uric Acid
This is an intervention study aiming to test the effectiveness of a vegan diet, My Plate with low purine choices, and amla fruits on uric acid and other cardiometabolic risk factors in individuals with high serum uric acid levels.
- Conditions
- Hyperuricemia, Diet, Healthy, Cardiometabolic Syndrome
- Trial name
- NCT04801745
- Testing
- Healthy vegan diet, My Plate - Low Purine, Amla fruits
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- Fu Jen Catholic University
Metabolic Syndrome, Overweight
Trial of Two Dietary Programs on Cardiometabolic Risk Factors in Subjects With Metabolic Syndrome
The objective of this study was to investigate from 3 sites (University of Connecticut, University of Florida, and University of California, Irvine) whether enhancement of a modified Mediterranean-style, low glycemic load diet…
- Conditions
- Metabolic Syndrome, Overweight, Obesity, Hypercholesterolemia
- Trial name
- HMS4 (NCT01010841)
- Testing
- UltraMealPlus 360 (Medical food), Low-glycemic-load diet
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- MetaProteomics LLC
Endocrine Disruptors, Inflammation
The Plastic Exposure Reduction Transforms Health Trial
The goal of this randomized controlled trial is to learn if an intervention of reducing plastic exposure through diet, personal care and cleaning products can improve health outcomes in adult participants with cardiometabolic…
- Conditions
- Endocrine Disruptors, Inflammation, Cardiometabolic Risk Factors
- Trial name
- PERTH (NCT06571994)
- Testing
- Low Plastic Intervention
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Western Australia
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity
Comparison of Anthropometric Parameters and Cardiometabolic Risk Factors Among Subjects With Overweight and Obesity
The study was aimed at comparing four different anthropometric parameters to cardiometabolic risk factors in overweight and obese subjects (Body Mass Index (BMI)≥25)
- Trial name
- NCT04318288
- Testing
- Observational
- Where
- Italy
- Volunteers
- 1,214 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Overweight and Obesity, Cardiometabolic Risk Factors
Effect of Vitamin K2 Over Osteocalcin, Leptin, Cytokines, and Cardiovascular Risk in Young Adults With Overweight and Obesity
The goal of this clinical trial is to compare de effect of vitamin K2 in young adults with overweight or obesity. The main questions to answer are: What is the effect of Vitamin K2 supplementation on methylation, serum…
- Trial name
- NCT05995522
- Testing
- Vitamin K2, Cornstarch
- Where
- Mexico
- Volunteers
- 51 people
- Sponsor
- University of Guadalajara
Cardiometabolic Risk Factors
Effect of Vitamin D on Cardiovascular Metabolic Risk in Overweight/Obesity Adolescents in China
The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on cardiometabolic risk in Chinese adolescents with overweight/obesity and vitamin D deficiency.
- Trial name
- NCT07053657
- Testing
- Dietary Supplement: Vitamin D3
- Where
- 2 sites in China
- Volunteers
- 130 people
- Sponsor
- Anhui Medical University
Cognition, Cardiometabolic Risk Factors
Trial of Pistachio Consumption in Older Adults
The goal of this study is to evaluate whether a pistachio-enriched diet leads to changes in cognitive function, cardiometabolic risk factors, and life satisfaction in older adults over a 6-month period.
- Conditions
- Cognition, Cardiometabolic Risk Factors, Life Satisfaction
- Trial name
- NCT06992544
- Testing
- Pistachio-enriched diet, Usual diet
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
PTSD, Cardiovascular Disease
Lifestyle and Cardiometabolic Risk in Post-9/11 Veterans
Heart disease and diabetes are leading causes of death and disability in the US, especially among Veterans. Posttraumatic stress disorder (PTSD) is a disabling condition that also affects many Veterans.
- Conditions
- PTSD, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT04911153
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Inflammation Biomarkers, Oxidative Stress
Effect of Ginger Capsules on Inflammation, Oxidative Stress, and Endothelial Function
Randomized, double-blind, parallel, placebo-controlled clinical trial designed and conducted to evaluate the effect of daily consumption of ginger, on parameters related to inflammation, oxidative stress, and endothelial damage…
- Conditions
- Inflammation Biomarkers, Oxidative Stress, Cardiometabolic Risk Factors
- Trial name
- NCT07437222
- Testing
- Ginger supplement
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Ana Mª Garcia Munoz
Attention Deficit Hyperactivity Disorder, Cardiovascular Diseases
ADHD Remote Technology Study of Cardiometabolic Risk Factors and Medication Adherence
Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder, with a prevalence among adults of 2.5%. The disorder is diagnosed based on impairing levels of inattentive, hyperactive and impulsive behaviours.
- Conditions
- Attention Deficit Hyperactivity Disorder, Cardiovascular Diseases, Medication Adherence
- Trial name
- ART-CARMA (NCT05301673)
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Sedentary, Cardiometabolic Syndrome
Effect of Interrupting Sedentary Time With Different Frequencies of Physical Activity on Cardiometabolic Risk Factors
The knowledge gap on sedentary behavior and sedentary breaks includes whether detrimental effects of sedentary behavior can be fully attenuated by 1.) sedentary breaks 2.) physical activity or 3.) both combined.
- Conditions
- Sedentary, Cardiometabolic Syndrome, Physical Activity
- Trial name
- NCT05622006
- Testing
- Sedentary breaks
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Obesity
Effect of Time-Restricted Feeding on Fat Loss and Cardiometabolic Risk Factors in Overweight Adults
Time-restricted feeding (TRF) is a novel type of intermittent fasting that involves eating within a daily period of 10 hours or less, followed by fasting for at least 14 hours daily.
- Trial name
- NCT03459703
- Testing
- Early Time-Restricted Feeding, Control Schedule, Structured Weight Loss Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sleep Deprivation, Insomnia
Sleep Chatbot Intervention for Emerging Black/African American Adults
Unhealthy sleep and cardiometabolic risk are two major public health concerns in emerging Black/African American (BAA) adults. Evidence-based sleep interventions such as cognitive-behavioral therapy for insomnia (CBT-I) are…
- Conditions
- Sleep Deprivation, Insomnia, Metabolic Syndrome
- Trial name
- NCT05956886
- Testing
- sleep chatbot
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Delaware