Clinical trials: Cardiometabolic Risk
Testicular Cancer
Short-term Testosterone Replacement in Testicular Cancer Survivors
To assess the effects of testosterone replacement therapy on fat mass and other components of the metabolic syndrome. A randomized double-blind placebo controlled intervention study, followed by an open-label treatment phase.
- Trial name
- NCT03339635
- Testing
- Androgel (Testosterone gel)
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- University Medical Center Groningen
Obesity, Pre-diabetes
Evaluation of Lifestyle Interventions to Treat Elevated Cardiometabolic Risk in Primary Care
The purpose of the E-LITE Study is to evaluate the feasibility and potential effectiveness of two lifestyle interventions in a community based primary care setting.
- Conditions
- Obesity, Pre-diabetes, Metabolic Syndrome
- Trial name
- E-LITE (NCT00842426)
- Testing
- Self-management program (SM), Care management program (CM)
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Palo Alto Medical Foundation
Dietary Behaviour, Dietary Intakes
The SWITCH Dietary and Behavioural Intervention Study
The overall objective of this study is to evaluate the effectiveness of an optimized lifestyle intervention based on dietary advice, behavioral support, and provision of key foods compared to dietary advice with behavioral…
- Conditions
- Dietary Behaviour, Dietary Intakes, Dietary Intervention, Metabolic Diseases
- Trial name
- SWITCH (NCT06973408)
- Testing
- Behavioral Treatment, Food support, Dietary Advice
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Diabetes, Hypertension
Implementation of an Integrated Primary Care Network for Prevention and Management of Cardiometabolic Risks
CONTEXTE: L'Agence de la santé et des services sociaux de Montréal (ASSS) invited our research team to evaluate the implementation of an integrated and interdisciplinary primary care network for prevention and management of…
- Trial name
- RCM (NCT01326130)
- Testing
- Chronic care management 1-6
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- Public Health Department, Montreal
Hypercholesterolemia
Assessing the Effects of Corn and Avocado Oils on the Cardiometabolic Risk Factor Profile
The goal of this clinical trial is to assess the effects of corn and avocado oils as part of controlled feeding diets on the cardiometabolic risk factor profile in men and women with mild-to-moderately elevated levels of…
- Trial name
- NCT07514663
- Testing
- corn oil, Avocado Oil
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Atherosclerosis, Metabolic Syndrome
Cardiometabolic Risk Factors Registry
CARFARE (CARDIOMETABOLIC RISK FACTORS REGISTRY) is a registry done in the context of a cardiovascular primary prevention program of the Cardiometabolic Unit Officia of the Cardiology Department of the Austral University Hospital.
- Conditions
- Atherosclerosis, Metabolic Syndrome, Diabetes, Cardiovascular Risk Factor
- Trial name
- CARFARE (NCT04040777)
- Where
- Argentina
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Austral University, Argentina
Metabolic Syndrome, Obesity
Virtual Enhanced Lifestyle for Metabolic Syndrome (ELM) Proof-of-Concept Study
This is a proof-of-concept study of a virtual version of a lifestyle intervention aimed at reducing cardiometabolic risk in patients with the Metabolic Syndrome (MetS).
- Trial name
- NCT04637477
- Testing
- Virtual ELM
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cardiovascular Diseases
Effects of a Legume-rich Diet in the Context of the Planetary Health Diet Compared to a Western-oriented Dietary Pattern in Participants with Increased Cardiometabolic Risk
The aim of the study is to systematically investigate the effects of a diet enriched with legumes in a dietary pattern approach (Planetary Health Diet) compared to a control diet low in legumes in older people with a risk…
- Trial name
- LeguPlan_2 (NCT06700954)
- Testing
- legume-rich Planetary Health Diet, control diet based on Western Diet low in legumes
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Bonn
Sleep Deprivation, Circadian Dysregulation
Cardiometabolic Risk of Shiftwork
The overall goal of the present application is to test the hypothesis that shift workers, who are chronically exposed to circadian misalignment and sleep loss, have a higher cardio-metabolic risk than day workers, and that the…
- Conditions
- Sleep Deprivation, Circadian Dysregulation, Shift-Work Sleep Disorder
- Trial name
- SW (NCT01264913)
- Testing
- sleep extension & circadian alignment
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Taurine, Aging, Biological
Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men
The goal of this clinical trial is to investigate the effect of taking 4 grams of taurine by older adults on aging processes over a period of 6 months.
- Conditions
- Taurine, Aging, Biological, Physical Activity, Metabolic Health
- Trial name
- TauAge (NCT06613542)
- Testing
- 4g of taurine daily
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Obesity, Metabolic Syndrome
Time Restricted Feeding to Reduce Weight and Cardiometabolic Risk
The obesity rate in Malaysia is higher than the average world obesity rate. Central obesity is a component of metabolic syndrome (MetS) which is also made up of dyslipidemia, impaired glucose tolerance, and hypertension.
- Conditions
- Obesity, Metabolic Syndrome, Pre Diabetes
- Trial name
- NCT04243746
- Testing
- Time Restricted Feeding, Standard Care
- Where
- Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- RCSI & UCD Malaysia Campus
Coronary Artery Disease, Cardiometabolic Risk Factors
Impact of New Anthropometric Indices on Outcomes After Cardiac Surgery
Obesity is associated with a number of risk factors for cardiovascular disease. Body mass index (BMI) is the most commonly recommended and used anthropometric measure to classify general obesity in clinical and epidemiological…
- Conditions
- Coronary Artery Disease, Cardiometabolic Risk Factors, Cardiac Anesthesia, Cardiac Surgery
- Trial name
- NCT05403294
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Childhood Obesity
Translational Investigation of Growth and Everyday Routines in Kids
The purpose of this study is to determine the effect of severe obesity on physical activity, sedentary behavior and cardiometabolic risk factors during childhood and adolescence and whether these associations are modified by…
- Trial name
- TIGER Kids (NCT02784509)
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity, Microalbuminuria
Evaluation of the Rimonabant Impact on the Regression of Asymptomatic Damage Caused by Cardiovascular Risk Factors
Primary objective: To assess the effect on microalbuminuria levels of treatment with rimonabant 20 mg versus a placebo during a 12 month period.
- Conditions
- Obesity, Microalbuminuria, Diabetes Mellitus, Type 2, Dyslipidemia
- Trial name
- RIALTO (NCT00458081)
- Testing
- Rimonabant
- Where
- Spain
- Volunteers
- 174 people
- Sponsor
- Sanofi
Obesity, Time Restricted Feeding
Time Restricted Feeding on Weight Loss and Cardio-protection (TREATY Trial)
Time restricted feeding (TRF) is a novel type of intermittent calorie restriction diet that involves eating a daily period of 8 hours or less.
- Conditions
- Obesity, Time Restricted Feeding, Weight Loss, Calorie Restriction
- Trial name
- TREATY (NCT03745612)
- Testing
- Time restricted feeding, Continuous Energy Restriction
- Where
- China
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Cardiometabolic Risk, Abdominal Obesity
Characterization of Gut Microbiota Composition and Activity After a Daily Supplementation of 4.5 g/Day of ChitinGlucan Fibre During 3 Weeks in At-cardiometabolic Risk Volunteers
The aim of this study is to demonstrate the beneficial effects on gut microbiota composition and activity of the diary intake of insoluble fiber (extract from Aspergillus Niger) for three weeks.
- Trial name
- FITACHITIN (NCT03773900)
- Testing
- Kiotransine (chitin-glucan from aspergillus niger)
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cardiometabolic Risk Factors
Fitbit-Tracked Micromovement for Cardiometabolic Health in Rural Women
This pilot study tests whether a low-burden prevention program can be integrated into routine care to identify and reduce cardiometabolic risk in rural women.
- Trial name
- RISE-W (NCT07704749)
- Testing
- RISE-W Micro-Movement Program
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Texas Tech University Health Sciences Center
Hypertension
Effects of the DASH vs. the Mediterranean Diet Combined With Salt Restriction on Blood Pressure Levels in Adults
Non-pharmacological measures should serve as the first-line treatment in individuals with high normal blood pressure (BP) levels or grade 1 hypertension and low-moderate cardiovascular disease risk.
- Trial name
- NCT05669404
- Testing
- Salt Restriction Group (SRG), DASH Diet combined with salt restriction Group (DDG), Mediterranean Diet combined with salt restriction Group (MDG)
- Where
- Greece
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hippocration General Hospital
Cardio Metabolic Risk
Impact of Prasterone on Cardiometabolic Indicators in Perimenopausal Women.
Perimenopause is the natural transition period towards menopause, in which the ovarian reserve begins to decrease, and the woman loses her fertility. It usually starts around the age of 40 and has a variable duration.
- Trial name
- NCT07609043
- Testing
- Prasterone 50 milligram
- Where
- Mexico
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad de Guanajuato
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Dietary Intervention to Improve Cardiometabolic Risk Profile in Individuals With Type 2 Diabetes
This is a randomized controlled trial to examine whether personalized guidance to increase the consumption of fiber rich food items according to the Dutch dietary guidelines, compared to usual care, improves health of individuals…
- Trial name
- VJBD2 (NCT05666843)
- Testing
- Personalized Dietary Advice
- Where
- Netherlands
- Volunteers
- 124 people
- Sponsor
- Wageningen University