Clinical trials: Cardiometabolic Risk Factors
Polyps, Cardiovascular Diseases
Lifestyle and Dietary Pattern in Relation to Precursor Lesions of Colorectal Cancer and Cardiometabolic Diseases
The association between lifestyle and dietary patterns with precursor lesions of colorectal cancer and cardiometabolic diseases is still unclear.
- Trial name
- NCT03708952
- Where
- 2 sites in China
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
People Who Are Overweight or Obesity
Effect of a Soluble Fibre Blend and Medium Chain Triglycerides on Body Composition and Cardiometabolic Risk Factors
The purpose of this study is to investigate whether the addition of capsules containing soluble fibre complex emulsified with medium chain triglycerides and taken before with meals will lead to a significant amount of weight…
- Trial name
- NCT00644098
- Testing
- soluble fibre complex and medium chain triglycerides, cellulose and soybean oil
- Where
- Canada
- Volunteers
- 138 people
- Sponsor
- Canadian Center for Functional Medicine
Obesity, Cardiovascular Risk Factors
Effects of Soy Based Dietary Supplements on Cardiometabolic Risk Factors.
This study will test the effect of both Luna Rich X© and Reliv Now© against placebo pills or powder (control) on blood lipids. It will also explore the potential effects of these dietary supplements on inflammation markers and…
- Trial name
- NCT02490683
- Testing
- Luna Rich X, Reliv Now
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Loma Linda University
Childhood Obesity
Translational Investigation of Growth and Everyday Routines in Kids
The purpose of this study is to determine the effect of severe obesity on physical activity, sedentary behavior and cardiometabolic risk factors during childhood and adolescence and whether these associations are modified by…
- Trial name
- TIGER Kids (NCT02784509)
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Severe Obesity Scheduled for Bariatric Surgery
Cardiometabolic Risk Factor Management and Adherence to Antihypertensive Therapy in Patients With Severe Obesity Prior to Bariatric Surgery: a Prospective Longitudinal Cohort Study
Patients with severe obesity frequently exhibit elevated cardiovascular risk. Contributing factors could be inadequate recognition and subsequent management of cardiovascular risk factors, and non-adherence to cardiovascular…
- Trial name
- NCT07441304
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universität des Saarlandes
Cardiometabolic Risk Factors in Adult Wheelchair Users
Cardiometabolic Health Intervention Using Movement-to-Music Exercise
The study aims to test the benefits of a 24-week, cardio-emphasized Movement-to-Music exercise program for reversing cardiometabolic health risk factors compared to asynchronous, standard exercise programs among 132 adult…
- Trial name
- CHIME (NCT05606432)
- Testing
- Instructor-led, one-on-one M2M exercise group, Self-guided control with pre-recorded standard exercise videos
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Alabama at Birmingham
Body Weight
Pulse Biomarker Discovery
Dietary pulses, including beans, chickpeas, and lentils, are high in soluble fiber with potential benefits to human health: Pulses are moderate energy density foods, low in fat and high in dietary protein, fiber, vitamins and…
- Trial name
- NCT04887584
- Testing
- Control diet, Low Pulse diet, High Pulse diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Gender Incongruence, Cardiovascular Disease (CVD) Risk Factors
Cardiomodulatory Effects of Gender-Affirming Hormone Therapy
Gender-affirming hormone therapy is today a well-established treatment for individuals experiencing gender-incongruence. However, little is known about the long-term effects of gender-affirming hormone therapy on the…
- Trial name
- CARMEN (NCT07128771)
- Where
- Norway
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Cardiovascular Diseases, Cardiovascular Risk Factor
The Use of Icosapent Ethyl on Vascular Progenitor Cells in Individuals With Elevated Cardiovascular Risk
IPE-PREVENTION is a prospective, randomized, 3-month long, open-label study. A total of 70 individuals with elevated cardio-metabolic risk and heightened triglyceride levels, and who are on stable statin therapy will be…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Triglycerides High, Diabetes Mellitus, Type 2
- Trial name
- IPE-PREVENTION (NCT04562467)
- Testing
- Icosapent Ethyl 1000 MG Oral Capsule [Vascepa]
- Where
- 3 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Bipolar Youth Treated With Second-generation Antipsychotics
SGA-induced Metabolic Syndrome in Bipolar Youth
The investigators tested the hypothesis that long-chain omega-3 (LCn-3) fatty acid supplementation will attenuate the adverse cardiometabolic effects of second-generation antipsychotics exposure in first-episode adolescent manic…
- Trial name
- NCT01858948
- Testing
- Omega, Quetiapine fumarate
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Cincinnati
Hypertension, Cardiovascular Disease
Meta-analyses of the Effect of Legumes on Blood Pressure
Legumes are generally recognized as healthy dietary components, and although beans and legumes are recommended in food guidelines in North America, guidelines vary in regards to how much and how often these foods should be…
- Conditions
- Hypertension, Cardiovascular Disease, Dyslipidemia, Diabetes
- Trial name
- NCT02600338
- Testing
- Legumes
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Cardiometabolic Risk Factors, Obesity, Abdominal
Powdered Fermented Fruits for Glycemia Reduction
The aim of the study is to evaluate the effects of an acute intake of two fermented fruits flours as part of a standardized breakfast, in comparison with the acute intake of a standardized breakfast without fermented fruits flour…
- Trial name
- P2F-GR (NCT04877548)
- Testing
- Fermented orange flour, Fermented grape flour, Control
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Physical Activity
Pedal@Work: A Worksite Wellness Program
The primary aim of this pilot study is to test the efficacy of a worksite intervention for reducing daily sedentary time and improving risk factors for cardiometabolic disease (e.g., measures of adiposity, anthropometrics…
- Trial name
- Pedal@Work (NCT01371084)
- Testing
- Pedal@Work Worksite Wellness, Pedal@Work
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Obesity, Cardiovascular Risk Factor
Healthy Nordic Foods to Prevent Cardiometabolic Risk in Obese Subjects
This project will examine whether long-term consumption of healthy Nordic foods can maintain a healthy weight also after weight loss, and decrease abdominal fat accumulation and cardiometabolic risk.
- Conditions
- Obesity, Cardiovascular Risk Factor, Diet Modification
- Trial name
- NCT03102853
- Testing
- Nordic diet, Control diet
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lund University
Immune Response, Cardiometabolic Risk Factors
Effects of Peanuts on Immunity and Cardiometabolic Risk Factors
The aim of the proposed study is two-fold: to determine whether the intake of peanuts (a) enhances immune function and (b) produces a desirable impact on selected cardiometabolic biomarkers and risk factors.
- Trial name
- NCT06159556
- Testing
- Peanut intake
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Gestational Diabetes
Intergenerational Programming of Diabesity in Offspring of Women With Gestational Diabetes Mellitus
India is one of the diabetes capitals in the world. Indians are susceptible to develop diabetes at a younger age and at a lower BMI compared to Europeans.
- Trial name
- InDiaGDM (NCT03388723)
- Where
- India
- Volunteers
- 1,178 people, healthy volunteers welcome
- Sponsor
- Kem Hospital, Pune, India
Obesity
Comparison of Anthropometric Parameters and Cardiometabolic Risk Factors Among Subjects With Overweight and Obesity
The study was aimed at comparing four different anthropometric parameters to cardiometabolic risk factors in overweight and obese subjects (Body Mass Index (BMI)≥25)
- Trial name
- NCT04318288
- Testing
- Observational
- Where
- Italy
- Volunteers
- 1,214 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Cardiovascular Disease (CVD), Elevated Cardiovascular Risk
Sacha Inchi-CoQ10 Supplementation and Cardiovascular Health
The goal of this clinical trial is to learn if Sacha Inchi-CoQ10 supplementation can improve cardiovascular health in adults who have an increased risk of cardiovascular disease.
- Conditions
- Cardiovascular Disease (CVD), Elevated Cardiovascular Risk, Endothelial Dysfunction
- Trial name
- Sacha-Q10 (NCT07792005)
- Testing
- Sacha-Q10 Plus
- Volunteers
- 60 people
- Sponsor
- Hospital Pengajar Universiti Putra Malaysia
Fitness Trackers, Cardio Vascular Disease
Effects of Wearable Device Functions and Health Coaching on Device-measured Movement Behaviours and Cardiometabolic Risk Factors in Adults With Central Obesity
This study is a randomized controlled trial. The objective of this study is to investigate: 1. the effects of 1-year evidence-based interventions incorporating wearable device functions alone on device-measured movement…
- Conditions
- Fitness Trackers, Cardio Vascular Disease, Physical Activities, Exercise
- Trial name
- NCT07379970
- Testing
- Fitbit Wearable Device, Lifestyle Coaching Program
- Where
- Hong Kong
- Volunteers
- 133 people
- Sponsor
- The University of Hong Kong
Metabolic Syndrome, Overweight
Effects of Lignan-rich Diet on Cardiometabolic Risk Factors
Diet plays an important role in relation to prevention of type 2 diabetes, cardiovascular disease and certain cancers. Studies have shown that diets with high whole-grain content could decrease the risk of these lifestyle related…
- Conditions
- Metabolic Syndrome, Overweight, Central Obesity, Impaired Glucose Tolerance
- Trial name
- NCT02987595
- Testing
- Whole-grain rye, high lignan, Whole-grain wheat, low lignan
- Where
- Sweden
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Swedish University of Agricultural Sciences