Clinical trials: Cardiometabolic Syndrome
Metabolic Syndrome , Sims Score and Pediatrics
Metabolic Syndrome and Sims Score
SiMSscore was used as a simple and accurate method for Quantifying Metabolic Syndrome in adults , Developed siMS score was calculated using formula: siMS score = 2*Waist/Height + Gly/5.6 + Tg/1.7 + TAsystolic/130-HDL/1.02 or 1.28…
- Trial name
- NCT04680702
- Testing
- Sims Score
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Metabolic Syndrome
Phospholipid and Sphingolipid Composition of High-density Lipoproteins (HDL) in Obese Non-diabetic Patients With Metabolic Syndrome
HDL in obese non-diabetic patients show major alterations in their function and thus their cardio-protective effects. These alterations could be explained by the quantitative and qualitative anomalies in the phospholipids and…
- Trial name
- SPHINGO (NCT02851602)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 89 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Obesity
Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial
A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS), combined with a lifestyle modification program, compared to a sham control and a lifestyle modification…
- Trial name
- VeSTAL (NCT03640286)
- Testing
- VeSTAL
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Cardiometabolic Syndrome, Hiv
The Role of Ectopic Fat and Heart Attack Risk in HIV
This study is designed to investigate differences between people living with HIV (PLWHIV) and general populations on how the body utilises and stores energy.
- Trial name
- BHIVA (NCT06784154)
- Testing
- Non-interventional
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Obesity, Diabetes Mellitus
Activating Brown Adipose Tissue Through Exercise
The energy burning capacity of brown adipose tissue makes it an attractive target for anti-obesity therapies. Sympathetic nervous system (SNS) is the classical regulator of brown adipose tissue; however, recent findings show a…
- Conditions
- Obesity, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- ACTIBATE (NCT02365129)
- Testing
- Exercise training based on recommendations for adults (WHO)
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Metabolic Syndrome
Prevalence of Metabolic Syndrome in Atahualpa
A recent epidemiologic survey demonstrated a high prevalence of type 2 diabetes mellitus in Atahualpa residents. Now, the investigators attempt to evaluate the prevalence of the metabolic syndrome in adults aged 40 years or more…
- Trial name
- NCT01770054
- Testing
- obtention of a blood sample
- Where
- Ecuador
- Volunteers
- 517 people, healthy volunteers welcome
- Sponsor
- Hospital Clínica Kennedy
Type 2 Diabetes, Obesity
Long-term Effects of Lifestyle Intervention During Pregnancy in High Risk Women and in Their Offspring - Role of Environmental, Genetic and Epigenetic Factors
SUBJECTS: All participants in the RADIEL-study (2008-2011) who delivered (n=535), will be invited to this follow-up study, with their children (age 3-5 years) and the father.
- Conditions
- Type 2 Diabetes, Obesity, Metabolic Syndrome
- Trial name
- NCT02048839
- Where
- Finland
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Periodontitis, Adult, Metabolic Syndrome
Genetic Variants and Oxidative Stress as Links Between Periodontitis and Metabolic Syndrome
The aim of this study is to investigate the systemic impact of periodontitis in patients with Metabolic Syndrome, by assessing measures of sub-clinical atherosclerosis and cardiovascular risk, microbial factors and host genetic…
- Trial name
- NCT03297749
- Testing
- Observational study (no intervention)
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 102 people
- Sponsor
- University College, London
Cardiovascular-kidney-metabolic Syndrome, Cardiovascular Disease Risk Factor
Early Add-On Combination of GLP-1 Receptor Agonist and SGLT2 Inhibitor in People With Cardiovascular-Kidney-Metabolic Stage 2-3
This retrospective observational target-trial emulation uses electronic health record data from the TriNetX US Collaborative Network to compare early treatment intensification strategies in adults with obesity, type 2 diabetes…
- Conditions
- Cardiovascular-kidney-metabolic Syndrome, Cardiovascular Disease Risk Factor, Kidney Disease, Type 2 Diabetes
- Trial name
- GLP1-SGLT2-CKM (NCT07465926)
- Testing
- GLP-1 receptor agonist, SGLT2 inhibitor
- Volunteers
- 451,036 people
- Sponsor
- Chung Shan Medical University
Aerobic Exercise, Strength Training
Home-Based Circuit Training in Overweight/Obese Older Adult Patients With Knee Osteoarthritis and Type 2 Diabetes
Background: Obesity and type 2 diabetes mellitus (T2DM) are considered two of the most prevalent metabolic diseases linked to the onset of knee pain caused by osteoarthritis.
- Conditions
- Aerobic Exercise, Strength Training, Glycemic Control, Blood Pressure
- Trial name
- NCT06309654
- Testing
- 12-week home-based circuit training (HBCT), Standard of care (CONT)
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Hyperandrogenism,, Polycystic Ovary Syndrome,
Presentations of Hyperandrogenic Phenotypes in Taiwanese Women
STUDY QUESTION: Which of the four abnormally elevated androgen groups (total testosterone [TT], androstenedione [A4], free androgen index [FAI], or dehydroepiandrosterone-sulfate [DHEA-S]) present with an unfavorable metabolic…
- Conditions
- Hyperandrogenism,, Polycystic Ovary Syndrome,, Metabolic Syndrome,, Insulin Resistance,
- Trial name
- NCT01940666
- Where
- Taiwan
- Volunteers
- 649 people
- Sponsor
- Taipei Medical University WanFang Hospital
Metabolic Syndrome, Type 2 Diabetes
Dairy Lipids, Proteins, and the Metabolic Syndrome - "DairyHealth"
Dairy food contains a large amount of long-chain saturated fat, which traditionally has been linked to increased risk of cardiovascular disease (CVD). However, recent data indicates a more neutral role.
- Conditions
- Metabolic Syndrome, Type 2 Diabetes, Cardiovascular Disease, Abdominal Obesity
- Trial name
- NCT01472666
- Testing
- High content of MC-SFA, Whey, Low content of MC-SFA
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- University of Aarhus
Metabolic Syndrome
Whole Soy Replacement Diet on Metabolic Features
Project title: A randomized controlled trial of whole soy diet in place of red/processed meat and high fat dairy products on metabolic features in postmenopausal women Objectives: Metabolic syndrome (MetS) is an escalating public…
- Trial name
- NCT02610322
- Testing
- Whole soy replacement diet, usual diet
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Healthy Diet, Fatty Liver
Metabolic Effects of Plant-based Diet
The purpose of this study is to assess the metabolic effects of plant based diet on healthy young adults.
- Conditions
- Healthy Diet, Fatty Liver, Insulin Resistance, Metabolic Syndrome
- Trial name
- NCT05351853
- Testing
- Omnivore, Vegetarian, Vegan
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Koç University
PCOS, Reproductive Age
Adipokines in Polycystic Ovary Syndrome
The aim of the study is to compare the concentrations of leptin, resistin, and omentin-1 in women across three research groups: those with polycystic ovary syndrome without insulin resistance, those with polycystic ovary syndrome…
- Trial name
- NCT06793072
- Testing
- Leptin concentration in blood serum, Resistin concentration in blood serum, Omentin-1 concentration in blood serum
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Osteoarthritis, Metabolic Diseases
P.A.R.Q.V.E III - Comparison of the Educational Program With and Without Multidisciplinary Care
BACKGROUND: Osteoarthritis (OA), and particularly knee osteoarthritis (KOA) is a disorder that greatly impairs the quality of life of patients and its incidence increases with longevity, obesity and lower socioeconomic and…
- Trial name
- PARQVE3 (NCT02917655)
- Testing
- Womac, Lequesne, Numerical Rating Scales (NRS)
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Metabolic Syndrome
Optimal Metabolic Health Through Continuous Glucose Monitoring
The primary focus of this study is to evaluate the role of Continuous Glucose Monitoring (CGM) with Levels Health software as a tool to provide feedback and accountability necessary to create sustainable behavioral changes in…
- Trial name
- CGM (NCT04920058)
- Testing
- Continuous Glucose Monitor, <Active Comparator?>
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Heart Failure, Metabolic Cardiovascular Syndrome
Cardiometabolic evalUation REgistry of Heart Failure
This is a combined retrospective-prospective observational cohort study investigating the role of systemic and local cardiometabolic risk factors in cardiac structural/functional remodeling and clinical outcomes among heart…
- Conditions
- Heart Failure, Metabolic Cardiovascular Syndrome, Metabolic Diseases
- Trial name
- CURE-HF (NCT06939985)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Ruijin Hospital
Twins, Metabolic Syndrome
Metabolic Syndrome Among Polish Twins
Over a 5-year follow-up period, we aim to conduct a study among twins aged 15-44 years from the Polish population with the following objectives: 1.
- Trial name
- TWINSPL (NCT07181018)
- Testing
- Trial within cohort (TWIC)
- Where
- Poland
- Volunteers
- 1,500 people
- Sponsor
- Poznan University of Medical Sciences
Hyperglycemia, Hypercholesterolemia
Glucose Metabolism Disorders and Metabolic Syndrome Before and After Primary Hip and Knee Replacement
Osteoarthritis patients undergoing primary hip and knee replacement are followed-up and changes in their glucose metabolism and other metabolic parameters (obesity, cholesterol levels) are examined.
- Conditions
- Hyperglycemia, Hypercholesterolemia, Persistent Postoperative Pain, Hip Replacement
- Trial name
- HyTe-2 (NCT01743313)
- Where
- Finland
- Volunteers
- 155 people
- Sponsor
- Coxa, Hospital for Joint Replacement