Clinical trials: Cardiopulmonary Exercise Test, active
Obesity, Hypertension
Exercise Effects on Cardiometabolic Health and Sestrin-2 in Hypertensive Obese Women
Obesity is a chronic and complex disease characterized by excessive fat accumulation that adversely affects health and quality of life.
- Trial name
- SES-EX (NCT07370363)
- Testing
- Moderate-Intensity Continuous Exercise, Brisk Interval Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Havva Talay Çalış
Abdominal Cancer, Pelvic Cancer
A Study to Determine Whether Perioperative Energy Dynamics Correlates With Postoperative Outcomes
To validate a new method for assessing perioperative risk in the cancer patient undergoing major cancer surgery. In this proposed study researchers will: 1. Measure preoperative energy reserve capacity (fitness) 2.
- Trial name
- NCT00493688
- Testing
- Cardiopulmonary Exercise Testing (CPET)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Bronchiectasis Adult, Healthy Controls Group - Age and Sex-matched
Cardiopulmonary Responses to 6-Minute Stepper Test in Bronchiectasis Versus Healthy Controls
Individuals with bronchiectasis exhibit productive cough and recurrent lung infections as well as reduced exercise capacity, physical activity level, and respiratory and peripheral muscle strength.
- Trial name
- NCT06631261
- Testing
- No intervention; Observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication
This randomized controlled trial aims to investigate the impact of conduction system pacing in comparison to right ventricular apical pacing on exercise capacity, as measured by peak oxygen uptake (VO2peak), in heart failure…
- Conditions
- Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction, Heart Conduction Disorder
- Trial name
- ESCPAND (NCT06278844)
- Testing
- Conduction system pacing, Right ventricular apical pacing
- Where
- Belgium
- Volunteers
- 75 people
- Sponsor
- University Hospital, Antwerp
Turner Syndrome
Cardiopulmonary Exercise Testing in Girls (8-18y) with Turner Sydrome.
The goal of this clinical trial is to have a beter insight in the exercise tolerance in girls with Turner Syndrome aged 8-18 years .
- Trial name
- NCT06780514
- Testing
- Cardiopulmonary exercise test
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Perioperative/Postoperative Complications, Aerobic Capacity
SHAPE Test for Preoperative Risk Stratification
This study is looking at whether a simplified exercise test called the SHAPE-HF cardiopulmonary testing system can be used before surgery in older adults.
- Trial name
- SHAPEPAT (NCT05743673)
- Testing
- Shape II
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Yale University
Frailty, Frailty/Sarcopenia
Clinical and Functional Effectiveness Assessment of Personalized Management Programs for Patients With Frailty
All participants underwent comprehensive geriatric assessment (CGA) and cardiopulmonary exercise testing (CPET). A personalized management program was developed for each patient, including recommendations on physical exercise…
- Trial name
- NCT07623694
- Testing
- Geriatric rehabilitation program based on CGA and CPET
- Where
- Russia
- Volunteers
- 115 people
- Sponsor
- Pirogov Russian National Research Medical University
Coronary Bypass Graft Stenosis, Valvular Heart Disease
Comparison of Post-operation Cardiopulmonary Capacity of Patients Underwent Conventional and Robot-assisted Coronary Artery Bypass Graft and Valve Replacement Surgery
Robotic surgery is one of the most popular minimally invasive procedures for patients with coronary artery disease or valvular diseases.
- Trial name
- NCT05430568
- Testing
- robot-assisted surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taichung Veterans General Hospital
Cardiac Surgery, Median Sternotomy
Early Rehabilitation in Patients Following Major Cardiac Surgery: Changes in Functional Capacity and Energy Efficiency in Walking and ADLs.
The main objective of this clinical trial is to evaluate exercise capacity before and after an inpatient or outpatient rehabilitation program in patients following major cardiac surgery.
- Trial name
- K5-POSTCCH (NCT07843316)
- Testing
- Use of COSMED K5, a portable metabolic system that allows real-time measurement of respiratory gas exchange, ventilation, and energy expenditure during physical activities.
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Acute Coronary Syndrome
Using Cardiopulmonary Exercise Test as an Incentive to Outpatient Cardiac Rehabilitation for Acute Coronary Syndrome Survivors.
Exercise-based cardiac rehabilitation is a class I recommendation for acute coronary syndrome (ACS) patients. However, participate rate of outpatient rehabilitation is quite low and remains a global issue.
- Trial name
- NCT05401240
- Testing
- information reveal
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taichung Veterans General Hospital
Heart Failure, Transplant; Failure, Heart
Cardiopulmonary Stress Testing (CPET) AlloSure Study
1. Cell-free DNA does not vary significantly as a function of the activity of immunologically quiescent cardiac transplant recipients, despite the metabolic demands of the transplanted organ.
- Trial name
- NCT04656080
- Testing
- CPET exercise testing
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Baylor Research Institute
HFpEF - Heart Failure With Preserved Ejection Fraction
Cardiopulmonary Exercise Testing-based High-intensity Interval Training For Improving Heart Failure With Preserved Ejection Fraction
Cardiovascular-Kidney-Metabolic (CKM) Syndrome is a continuous clinical disease spectrum integrating cardiovascular, renal, and metabolic disorders.
- Trial name
- CPHIT-HFpEF (NCT07693049)
- Testing
- High-intensity interval training
- Where
- 13 sites in China
- Volunteers
- 192 people
- Sponsor
- Peking University Third Hospital
Cardiopulmonary Exercise Test Interpretation
AI-Assisted Anaerobic Threshold Interpretation in Cardiopulmonary Exercise Testing
This prospective randomized two-period crossover reader study will evaluate whether assistance from a frozen artificial intelligence model improves physicians' interpretation of the anaerobic threshold (AT) in cardiopulmonary…
- Trial name
- PACE-Reader (NCT07833137)
- Testing
- AI-Assisted Anaerobic Threshold Interpretation, Unassisted Cardiopulmonary Exercise Test Interpretation
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Cardiopulmonary Exercise Test
Automated CPET Interpretation: International Validation Study
The goal of this observational experimental study is to validate a rule-based algorithm to automate CPET interpretation. The endpoints of this study are the following: The change in agreement between key opinion leaders (KOLs)…
- Trial name
- NCT07534384
- Where
- 3 sites in Belgium
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Metabolic Dysfunction-Associated Fatty Liver Disease
CPET-based HIIT for MAFLD
High-intensity interval training (HIIT), as an individualized exercise training mode based on cardiopulmonary exercise testing (CPET), is characterized by high-intensity training sessions interspersed with short rest periods.
- Trial name
- CEPHIT (NCT07177963)
- Testing
- HIIT, No specific exercise intervention.
- Where
- 5 sites in China
- Volunteers
- 54 people
- Sponsor
- Tang Yida
Pulmonary Arterial Hypertension (PAH)
Telerehabilitation in Pulmonary Arterial Hypertension
Context: Pulmonary arterial hypertension (PAH) causes severe exercise intolerance and reduced quality of life, while access to supervised rehabilitation remains limited.
- Trial name
- TRHP-001 (NCT07799675)
- Testing
- Home-based telerehabilitation program
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
MACE, Cardiac Death
Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform
The goal of this observational study is to observe the characteristics of cardiopulmonary exercise testing (CPET) parameters in patients across different cardiovascular diseases and to evaluate the predictive value of…
- Conditions
- MACE, Cardiac Death, Unplanned Repeat Revascularization, Cardiac Rehospitalization
- Trial name
- China-CPET (NCT07130968)
- Where
- China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Neoplasms, Immunotherapy
IMMUNO-FIT Observational Study
This observational study will investigate how immunotherapy affects physical fitness, quality of life, and treatment tolerance in adults with solid cancers.
- Conditions
- Neoplasms, Immunotherapy, Physical Fitness, Quality of Life
- Trial name
- NCT07354971
- Testing
- Observational Study - No Study Intervention
- Where
- United Kingdom
- Volunteers
- 67 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Lung Cancer (NSCLC)
Cardiorespiratory Fitness After Lobectomy Versus Sublobar Resection
This observational study will compare changes in cardiorespiratory fitness after lobectomy and sublobar resection. Sublobar resection includes segmentectomy and wedge resection.
- Trial name
- NCT07841249
- Testing
- Lobectomy, Sublobar Resection
- Where
- China
- Volunteers
- 604 people
- Sponsor
- Tongji Hospital