Clinical trials: Cardiopulmonary Resuscitations
Cardiac Arrest
Comparison of Chest Compressions Performed With the Lower Limb and the Classical Method (Lower_limb_CPR).
Chest compressions, alongside early defibrillation, are the most important component of basic life support for adults. High-quality compressions give the patient a chance to survive cardiac arrest.
- Trial name
- Lower_limb_CPR (NCT07646496)
- Testing
- Instruction to perform chest compressions using the lower limb (foot)
- Where
- Poland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Marcin Muża
Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
Pupillometry and Somatosensory Evoked Potential in Cardiac Arrest
Somatosensory Evoked Potentials (SSEP) and Pupillary Light Reflex (PLR) are key methods for neurologic prognostication in comatose survivors of cardiac arrest.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation, Resuscitation
- Trial name
- PASCA (NCT04720482)
- Testing
- Somatosensory Evoked Potentials, Automated Pupillometry
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
Cardiac Arrest
Use of a Metronome in Cardiopulmonary Resuscitation: A Simulation Study
The purpose of this study is to determine if the use of a metronome improves chest compression rate and depth during cardiopulmonary resuscitation (CPR) on a pediatric manikin.
- Trial name
- NCT02511470
- Testing
- Metronome on, Metronome off
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Cardiopulmonary Arrest With Successful Resuscitation, ACS - Acute Coronary Syndrome
Add-on Cangrelor in STEMI-triggered Cardiac Arrest
In patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary angioplasty (PCI) P2Y12 receptor (P2Y12r) inhibition should be achieved as soon as possible.
- Conditions
- Cardiopulmonary Arrest With Successful Resuscitation, ACS - Acute Coronary Syndrome, Hypothermia, Induced
- Trial name
- NCT03273075
- Testing
- Cangrelor, Prasugrel, Ticagrelor
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Cardiac Arrest, Out-Of-Hospital, Cardiac Arrest With Successful Resuscitation
CardioPulmonary Resuscitation With Argon (CPAr) Trial
Preclinical studies suggest that argon (Ar) might diminish the neurological and myocardial damage after any hypoxic-ischemic insult.
- Trial name
- CPAr (NCT05482945)
- Testing
- Noble gas Argon
- Where
- 9 sites in Italy
- Volunteers
- 120 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Airway Aspiration, Cardiopulmonary Arrest
Benefit of the SALAD Technique on CPR Quality During Intubation in Contaminated Airway
Management of airways in contaminated environments can compromise the quality of cardiopulmonary resuscitation (CPR). This study examined the effectiveness of SALAD (Suction Assisted Laryngoscopy Airway Decontamination) compared…
- Trial name
- NCT06427655
- Testing
- SALAD intubation
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Out-Of-Hospital Cardiac Arrest
Enhanced Community First Responder System Evaluation in Singapore
The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR).
- Trial name
- TCPR-Link (NCT06530433)
- Testing
- CPRCard + TCPR Link App and Web, CPRCard Only
- Where
- Singapore
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Pediatric, Cardiopulmonary
Pediatric Endotracheal Intubation During Resuscitation
Endotracheal intubation (ETI) is perceived as the optimal method of providing and maintaining a clear and secure airway. The 2010 European Resuscitation Council (ERC) guidelines emphasized the importance of minimal interruption…
- Trial name
- PETI (NCT02286297)
- Testing
- McGRATH® MAC, AirTraq, GlideScope
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Cardiopulmonary Resuscitation
Influence of Therapeutic Hypothermia on Resting Energy Expenditure
The purpose of this study is the evaluation of the influence of therapeutic hypothermia on resting energy expenditure (REE) in patients after cardiopulmonary resuscitation (CPR).
- Trial name
- NCT00500825
- Testing
- Measurement of Resting Energy Expenditure
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Medical University of Vienna
Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
Impact of NIRS-guided Cardiopulmonary Resuscitation After Cardiac Arrest on Resuscitation Rate
Sudden cardiac death is one of the main causes of morbidity and mortality worldwide. Cardiac arrest requires prompt intervention by cardiopulmonary resuscitation (CPR).
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation, Cerebral Oxygenation
- Trial name
- NICA (NCT03911908)
- Testing
- Cerebral oximetry (near infrared) based CPR-Algorithm
- Where
- Germany
- Volunteers
- 360 people
- Sponsor
- Dr. Serge Thal
Apnea, Cardiopulmonary Resuscitation
Head Positions to Open the Upper Airway
Ventilation during basic life support improves survival in cardiac arrest patients significantly. Unfortunately, this is in contrast to the willingness of potential rescuers to perform mouth-to-mouth ventilation.
- Trial name
- NCT00869648
- Testing
- Extension, Neutral head position, Anaesthesiologist's position
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Leg Elevation, Hemodynamic Instability
Passive Leg Raise During Cardiopulmonary Resuscitation
during cardiopulmonary resuscitation, an important element of the procedure is to achieve optimal organ perfusion. For this purpose, high quality chest compressions is one of the basic elements of the procedure.
- Conditions
- Leg Elevation, Hemodynamic Instability, Cardiopulmonary Resuscitation
- Trial name
- NCT03617978
- Testing
- Hemodynamics parameters
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Lazarski University
Leadership
Position of Teamleader and Leadership Performance
Investigation in simulated cardiac arrests. Team leaders are randomly designated. Designated teamleaders are instructed to lead their team from the position of the patient's head or remote from the patient.
- Trial name
- LeadPos (NCT04824508)
- Testing
- position
- Where
- Switzerland
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Advanced Cardiac Life Support, Cardiopulmonary Resuscitation, Tidal Volume, Manual Ventilation
Assessing Respiratory Rate and Tidal Volume Delivery During Manual Ventilation
Excessive minute ventilation for patients who experience cardiac arrest may cause pulmonary injury and decrease the overall effectiveness of cardiopulmonary resuscitation (CPR).
- Trial name
- NCT03544164
- Testing
- Manual Ventilation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Rush University Medical Center
Comorbidities and Coexisting Conditions, Cardiopulmonary Resuscitation
Charlson Comorbidity Index and Outcome of Cardiopulmonary Resuscitation in Geriatric Patients in Hong Kong
The goal of this observational study is to learn about the factors affecting the outcome (survival) of cardiopulmonary resuscitation in older persons in a hospital.
- Conditions
- Comorbidities and Coexisting Conditions, Cardiopulmonary Resuscitation, Geriatrics
- Trial name
- NCT06209944
- Testing
- Cardiopulmonary resuscitation
- Where
- China
- Volunteers
- 394 people
- Sponsor
- Jane Yidan Zhu
Critical Illness
CPR Audiovisual Tool to Impact ICU Patients' Surrogate Anxiety Level.
Video or No Video to decrease HCPOA/LAR anxiety and increase knowledge as it pertains to CPR.
- Trial name
- NCT03630965
- Testing
- CPR Video
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Medical College of Wisconsin
Cardiopulmonary Resuscitation
Optimizing Integration of CPR Feedback Technology With CPR Coaching for Cardiac Arrest
There is significant data showing that the quality of CPR performed is quite poor. Recent studies have shown that when real-time visual corrective feedback is available to CPR providers, quality (compression depth and rate)…
- Trial name
- NCT03204162
- Testing
- CPR Coaching
- Where
- 5 sites in United States, Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Out-Of-Hospital Cardiac Arrest
Silesian Registry of Out-of-Hospital Cardiac Arrests
Silesian Registry of Out-of-Hospital Cardiac Arrests (SIL-OHCA) which is an initiative of the Voivodeship Rescue Service in Katowice in cooperation with the Silesian Center for Heart Diseases in Zabrze is a prospective…
- Trial name
- SIL-OHCA (NCT03654859)
- Testing
- cardiopulmonary resuscitation
- Where
- Poland
- Volunteers
- 1,560 people
- Sponsor
- Silesian Centre for Heart Diseases
Cardiac Arrest
Intraosseous Access During Pediatric Resuscitation
The purpose of this study was to compare the Jamshidi, the BIG, the Cook, the EZIO intraosseous devices to standard peripheral venous catheterization during pediatric resuscitation.
- Trial name
- IOCPR (NCT02305511)
- Testing
- Peripheral venous catheterization, Jamshidi, BIG
- Where
- Poland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Cardiac Arrest
The Rescuer Fatigue During Cardiopulmonary Resuscitation in Manikin by Using Personal Protective Equipment.
Background: High-quality cardiopulmonary resuscitation is the key to recovering patients with sudden cardiac death. However, when the environment is exposure to biologic hazard, the medical personnel need to use different…
- Trial name
- NCT04802109
- Testing
- wearing level D personal protective equipment, wearing Level C personal protective equipment with N-95, wearing Level C personal protective equipment with Powered Air-Purifying Respiratory
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- An-Nan Hospital, China Medical University