Clinical trials: Cardiovascular Biomarkers
Arrhythmia Atrial, Atrial Fibrillation
Atrial Fibrillation Research In CATalonia
The AFRICAT study is a prospective, multicenter, population-based study, which aims to create and apply a sequential screening program for atrial fibrillation (AF) in a high-risk population by integrating clinical…
- Conditions
- Arrhythmia Atrial, Atrial Fibrillation, Hypertension, Diabetes Mellitus
- Trial name
- AFRICAT (NCT03188484)
- Where
- 2 sites in Spain
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Non-hodgkin Lymphoma, Multiple Myeloma
A Study of Voice as a Way to Monitor for Side Effects in People Receiving CAR T-Cell Therapy
The purpose of this study is to collect voice recordings and nervous system (neurologic) assessments from people with non-Hodgkin lymphoma (NHL) or multiple myeloma (MM) who are receiving standard treatment with CAR T-cell…
- Trial name
- NCT07249528
- Testing
- Audio Tasks
- Where
- 8 sites in United States
- Volunteers
- 20 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cardiovascular Diseases, Type 2 Diabetes
Enhanced Multicenter Dietary Portfolio Study
"Is it possible to recruit and retain up to 200 participants in a Randomize Control Trial (RCT) of high impact lifestyle approach of diet and exercise designed to significantly reduce cardiovascular events in middle-aged and…
- Conditions
- Cardiovascular Diseases, Type 2 Diabetes, Hypercholesterolemia
- Trial name
- EDP8 (NCT01954472)
- Testing
- Enhanced portfolio plus structured exercise, High fiber diet plus routine exercise
- Where
- 4 sites in Canada
- Sponsor
- Unity Health Toronto
Stroke, Acute Ischemic
Potential Use of a POCT for the Direct Transfer of Stroke Patients From the Ambulance to the Thrombectomy Center
Stroke is the leading cause of long-term disability and the second most common cause of death worldwide. Currently, the protocols require the imaging techniques at the hospitals to differ ischemic strokes with large vessel…
- Trial name
- NCT05833945
- Testing
- Large Vessel Occlusion Biomarkers Test
- Where
- 16 sites in Spain
- Volunteers
- 355 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Acute Myocardial Infarction, Subclinical Depression
SUBDIMA: Subclinical Depression in Acute Myocardial Infarction (SUBDIMA25)
This is an exploratory, prospective, non-profit study (SUBDIMA) designed to investigate the prevalence and potential prognostic significance of subclinical depression in patients admitted with a first acute myocardial infarction…
- Trial name
- SUBDIMA25 (NCT07492537)
- Testing
- Psychological, Cognitive, and Patient-Reported Outcome Assessments
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Heart Failure, Heart Dilation
The Use of Blood Biochemical Markers for Diagnostics of Heart Muscle Diseases
The aim of the study is to determine the analytical characteristics of the microRNA enzymatic immunoassay (miREIA) method and to determine various relations among miRNA biomarkers and heart failure (HF) with reduced ejection…
- Conditions
- Heart Failure, Heart Dilation, Left Ventricular Hypertrophy
- Trial name
- NCT05726695
- Testing
- microRNA test, Heart ultrasound examination
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Ostrava
Cardiac Insufficiency
Time Course of Circulating Myocardial Biomarkers After a TASH Procedure.
The study evaluates the released myocardial substances in blood of HOCM patients after TASH procedure (small "controlled" myocardial infarction).
- Trial name
- TASH (NCT03648736)
- Testing
- blood withdrawal
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- RWTH Aachen University
Peripheral Arterial Disease
Serum Levels of Klotho as a Possible Biomarker of Peripheral Artery Disease
Klotho, a membrane-bound protein co-receptor for fibroblast growth factor 23 (FGF23), is involved in atherosclerotic process and cardiovascular diseases. It regulates blood glucose and cholesterol levels.
- Trial name
- NCT05757271
- Where
- Italy
- Volunteers
- 207 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Preeclampsia, Eclampsia
Cardiac Biomarkers in Preeclampsia: Prediction of Disease and the Risk of Future Cardiovascular Events in Survivors
SUMMARY Background: Improvements in the management and prevention of obstetric haemorrhage and sepsis, in addition to magnesium sulphate for preeclampsia have led to significant reduction in global maternal mortality rates; thus…
- Trial name
- PreeclampBIO (NCT04468763)
- Where
- Nigeria
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Babcock University
Cardio-Oncology, Cardiomyopathy Due to Drug
Immune Checkpoint Inhibitor Therapy for Cancer and Risk of Myocarditis or Cardiomyopathy
Patients undergoing dual treatment with Immune checkpoint inhibitors (ICI) for various cancers, e.g. melanoma, are at increased risk of developing myocarditis and cardiomyopathy.
- Trial name
- NCT06309862
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cardiac Sudden Death, Hypoxia Brain
New Biomarkers of Neurological Outcome After a Sudden Cardiac Death
The aim of the project is to establish the value of circulating microparticles as a new biomarker for neurological prognosis of patients recovered from sudden cardiac death who remain comatose.
- Conditions
- Cardiac Sudden Death, Hypoxia Brain, Cell Membrane Microparticles, Biomarkers
- Trial name
- NCT03962361
- Testing
- Concentration of circulating microparticles.
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Coronary Syndrom, Chronic Obstructive Pulmonary Syndrom
Pneumological Acute Coronary Syndrom (ACS) Phenotyping Aachen
In this open, monocentric, observational study acute coronary syndrom (ACS) patients will be characterized by pneumological examination concerning a concomitant chronic obstructive pulmonary disease (COPD).
- Trial name
- PAPA (NCT02587481)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Hypertension, Dyslipidemia
Supplementation With Flaxseed Oil in the State of Rio de Janeiro
The purpose of this study is to evaluate the effect of supplementation with flaxseed oil combined with a nutritional counseling in reducing cardiovascular risk factors in homocysteine , biomarkers of inflammation, oxidative…
- Trial name
- NCT01604681
- Testing
- Flaxseed Oil
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Drunk Driving, Alcohol Drinking
Design and Evaluation of an In-Vehicle Real-Time Drunk Driving Detection System
To analyze driving behavior of individuals under the influence of alcohol while driving in a real car. Based on the in-vehicle variables, the investigators aim at establishing algorithms capable of discriminating sober and drunk…
- Conditions
- Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT05796609)
- Testing
- Driving under the influence of alcohol
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Malignant Hypertension
Determinants of Malignant Hypertension Onset and Related Target Organ Damages: the HAMA Biobank
The HAMA bank is an initiative aimed at collecting, preparing, and storing biological samples from patients treated for malignant hypertension and included in the HAMA cohort.
- Trial name
- HAMABANK (NCT06629363)
- Testing
- biobank
- Where
- 11 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier de PAU
Coronary Artery Disease, Left Ventricular Dysfunction
PRE-DETERMINE Cohort Study
This is a prospective, multi-center cohort study of patients with a history of coronary artery disease (CAD) and documentation of either a prior myocardial infarction (MI) or mild to moderate left ventricular dysfunction (LVEF…
- Conditions
- Coronary Artery Disease, Left Ventricular Dysfunction, Sudden Cardiac Death
- Trial name
- NCT01114269
- Where
- 90 sites in United States, Canada and 1 more
- Volunteers
- 5,764 people
- Sponsor
- Brigham and Women's Hospital
Acute Coronary Syndrome With ST Elevation on Electrocardiogram, Acute Coronary Syndrome Without ST Elevation on Electrocardiogram
Tryptase and Coronary Heart Disease
The main aim of this study will evaluate differences in serum levels of tryptase in study population. Will be selected a number of 350 patients hospitalized for coronary heart disease.
- Conditions
- Acute Coronary Syndrome With ST Elevation on Electrocardiogram, Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Noncritical Coronary Artery Disease Coronary Stenosis Less Than 50 Per Cent, Aortic Aneurysms
- Trial name
- NCT01618279
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Niguarda Hospital
Aging, Cardiovascular Risk Factor
A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovascular Risk Factors.
The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without…
- Trial name
- ACTIONcR (NCT04962061)
- Testing
- Cognitive Training, Aerobic and resistance exercises, Stretching and Toning
- Where
- Canada
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Louis Bherer
Chronic Inflammatory Disease, Angioedema
Deployment o the Multidisciplinary Prospective Cohort Imminent
Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and…
- Conditions
- Chronic Inflammatory Disease, Angioedema, Severe Asthma, Lupus
- Trial name
- IMMINeNT (NCT04334031)
- Testing
- Biobanking with genetic analysis, SF-12 questionnaire
- Where
- France
- Volunteers
- 2,200 people
- Sponsor
- University Hospital, Lille
Uric Acid, Cardiovascular Diseases
Acute Effects of Tart Cherry on Uric Acid and Biomarkers of CVD Risk in Healthy Individuals
This study aims to provide evidence as to whether consumption of tart cherry juice can reduce the risk of gout and cardiovascular disease (CVD) in an acute context.
- Conditions
- Uric Acid, Cardiovascular Diseases, Gout
- Trial name
- NCT04960527
- Testing
- Tart cherry juice, Water
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
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