Clinical trials: Cardiovascular Care
Pulmonary Disease, Chronic Obstructive
Assessment of Comorbidities in Chronic Obstructive Pulmonary Disease (COPD) in European Symptomatic Subjects From Primary Care
This is a prospective, observational, non-drug interventional, non-randomized study to compare the rate of moderate-severe COPD exacerbations in patients of all Chronic Obstructive Pulmonary Disease (COPD) severities with and…
- Trial name
- ACCESS (NCT01516528)
- Testing
- Spirometry
- Where
- 233 sites in Belgium, France and 4 more
- Volunteers
- 3,500 people
- Sponsor
- GlaxoSmithKline
Chronic Kidney Disease, Hemodialysis
Skill Building Education of Arteriovenous-Fistula Self-Care Behaviors and Quality of Life of Patients on Hemodialysis
The purpose of this study is to assess the effectiveness of skill building educational interventions in improving the self-care behaviors and quality of life of AVF in hemodialysis patients. This study will address questions.
- Conditions
- Chronic Kidney Disease, Hemodialysis, Hemodialysis Access Failure
- Trial name
- NCT06947772
- Testing
- Skill building education
- Where
- Pakistan
- Volunteers
- 274 people
- Sponsor
- Shifa Tameer-e-Millat University
Intubation
A Systematic Echography During Intubation Procedure to Predict Cardiovascular Collapse
In the operating room, most intubation procedures (IP) are scheduled and performed on hemodynamically stable patients. In the ICU, IP is frequently performed in emergent patients, because of unstable hemodynamics and/or acute…
- Trial name
- EPIC (NCT03184207)
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Brest
Hypertension
A Team-Based Care for Hypertension Management (TBC-HTA)
The purpose of this study is to determine whether a team-based care (TBC) intervention, combining physician, nurse and pharmacist care improves BP control compared to usual care at 6 months among outpatients with uncontrolled…
- Trial name
- TBC-HTA (NCT02511093)
- Testing
- TBC intervention
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Depression and CVD
A Patient Activation Approach to Implementing Depression Treatment in Cardiac Patients
This study, which is being conducted as part of a Quality Improvement (QI) Initiative at Columbia University Irving Medical Center, will test whether delivering the iHeart DepCare tool increases real world reach and adoption of…
- Trial name
- iHeart_2 (NCT07390331)
- Testing
- iHeart Depcare tool
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
Diabetes Mellitus, Type 2, Coronary Artery Disease
Optimizing Audit and Feedback for Primary Care
There remains a large gap between ideal and actual care provided to patients with chronic diseases. Performance feedback reports are often used as a foundation for quality improvement interventions.
- Trial name
- NCT00996645
- Testing
- Worksheet to facilitate goal-setting and action plans
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Chronic Heart Failure (CHF)
A Prospective Evaluation of Natriuretic Peptide Based Referral of CHF Patients in Primary Care
This low interventional study, whose unique intervention was to measure the blood level of a biomarker called NT-proBNP in chronic heart failure patients daily followed-up by Primary Care Physicians (PCPs) in Europe, assessed if…
- Trial name
- PREFER (NCT02807857)
- Testing
- Standard care
- Where
- 191 sites in Belgium, Croatia and 16 more
- Volunteers
- 1,415 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
iMedA: Improving MEDication Adherence Through Person-Centered Care and Adaptive Interventions
The aim of this study is to design, implement, and evaluate an adaptive personalized digital intervention, to be delivered through a mobile application, to increase medication adherence and self-care management for persons with…
- Trial name
- iMedA (NCT04413500)
- Testing
- Reminder, Educational message, Motivational messages
- Volunteers
- 32 people
- Sponsor
- Halmstad University
Cardiac Arrest, Therapeutic Hypothermia
SEVOflurane Inhalation in CARdiac Arrest Resuscitated Patients Treated With Therapeutic Hypothermia
Studying the feasibility of an initial sedation with inhalated sevoflurane during therapeutic hypothermia of cardiac arrests resuscitated patients.
- Trial name
- SEVOCAR (NCT02201134)
- Testing
- sevoflurane
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Childhood, Behavior, Eating
Pediatric Obesity Management Study
Childhood obesity is a critical public health issue. Obesity in childhood is associated with many complications, including high blood pressure, type II diabetes mellitus, abnormal blood lipid values, obstructive sleep apnea…
- Trial name
- NCT05622981
- Testing
- Age-specific educational materials and monitoring
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Corewell Health East
Dementia, Alzheimer Disease
Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers
The goal of this clinical trial is to evaluate Kinto's Care Coaching intervention for dementia caregivers. The main questions it aims to answer are: Does the intervention help caregivers to address their general caregiving goals…
- Conditions
- Dementia, Alzheimer Disease, Lewy Body Disease, Vascular Dementia
- Trial name
- NCT05916664
- Testing
- Kinto Care Coaching
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Kinto
Out-of-Hospital Cardiac Arrest, Hypoxic-Ischemic Brain Injury
Minimal Sedation Versus Standard Continuous Sedation After Out-of-Hospital Cardiac Arrest
Most patients resuscitated from out-of-hospital cardiac arrest (OHCA) remain comatose on hospital admission and are routinely managed with continuous sedation.
- Conditions
- Out-of-Hospital Cardiac Arrest, Hypoxic-Ischemic Brain Injury, Post-Cardiac Arrest Syndrome
- Trial name
- NCT07895771
- Testing
- Minimal sedation, Standard continuous sedation
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Ljubljana
Heart Failure
Problem-Solving for Rural Heart Failure Dyads
This study will develop and test the effectiveness of a culturally-sensitive, telephone-based, tailored dyadic problem-solving intervention to improve self-care in rural heart failure (HF) dyads.
- Trial name
- NCT04549181
- Testing
- Phase II: Problem-Solving for Rural HF Dyads
- Where
- 9 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Florida State University
Acute Coronary Syndrome, Myocardial Ischemia
Shared Care Rehabilitation After Acute Coronary Syndrome
Cardiac rehabilitation is an individual adapted multidisciplinary intervention for people suffering from Heart Disease. It involves; Dietary counseling, Exercise training, Psychosocial support, Physician smoking cessation Patient…
- Conditions
- Acute Coronary Syndrome, Myocardial Ischemia, Acute Myocardial Infarction: Rehabilitation Phase
- Trial name
- SHARED-REHAB (NCT01522001)
- Testing
- Shared Care model
- Where
- 3 sites in Denmark
- Volunteers
- 212 people
- Sponsor
- University of Aarhus
Hypertension, High Blood Pressure
Digital Education for Hypertension Management: Effects on Self-Care and Health Literacy
The goal of this clinical trial is to learn whether a digital education program can help people with high blood pressure (hypertension) manage their condition better.
- Trial name
- DIGIHYPE-HTN (NCT07506707)
- Testing
- Hypertension Self-Management and E-Health Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 181 people
- Sponsor
- Bartın Unıversity
Extracorporeal Circulation; Complications, Coagulation Disorder
Impact of Cardiac Surgery With a Minimal Invasive Extracorporeal Circuit οn Coagulation: Data From Point of Care Devices
This study includes patients undergoing elective cardiac surgery on MiECC. Coagulation status is assessed with ROTEM (TEM International GmbH, Munich, Germany) and Platelet function with impedance aggregometry using the…
- Conditions
- Extracorporeal Circulation; Complications, Coagulation Disorder, Extracorporeal Circulation of Blood; Thrombocytopenia
- Trial name
- NCT04159064
- Testing
- Thromboelastometry, Impedance Aggregometry
- Where
- Greece
- Volunteers
- 57 people
- Sponsor
- AHEPA University Hospital
Stroke, Caregiver Social Support
Optimizing Stroke Family Caregiver Support Across the Care Continuum by Improving the Timing of Intervention Delivery
About 50% of stroke survivors have limitations in their activities of daily living on return to the community. Family caregivers provide invaluable support to these individuals during their recovery and rehabilitation.
- Conditions
- Stroke, Caregiver Social Support, Caregiver Mental Health, Caregiver Sense of Control Over Life
- Trial name
- NCT00958607
- Testing
- Timing it Right Stroke Family Support Person Intervention, Self-directed program
- Where
- Canada
- Volunteers
- 310 people
- Sponsor
- University of Toronto
Cardiovascular Diseases, Cholesterol, LDL
Reducing Disparities in Primary Prevention of Cardiovascular Disease
Cardiovascular disease (CVD) is the leading cause of disparities in years of life lost by race and low socioeconomic status. Statins have been shown to decrease the risk of cardiovascular events among individuals with high CVD…
- Trial name
- NCT01610609
- Testing
- Population Health Management Intervention
- Where
- 3 sites in United States
- Volunteers
- 646 people
- Sponsor
- Northwestern University
Acute Circulatory Failure
Peripheral Tissue Perfusion in Intensive Care
Tissue perfusion has been identified as an early prognosis factor in patients admitted to intensive care. However, little is known about the effects of different hemodynamic interventions performed in clinical routine on…
- Trial name
- INPPEREA (NCT06384287)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Shock, Aortic Valve Disease
Non-invasive Prediction of Fluid and Noradrenaline Responsiveness Using the Carotid Wave Intensity.
The goal of this observational study is to study a new method to compute ventricular-arterial coupling (VAC) in adult intensive care patients after cardiac surgery.
- Conditions
- Shock, Aortic Valve Disease, Coronary Artery Disease, Mitral Valve Disease
- Trial name
- VACC (NCT06197321)
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Catharina Ziekenhuis Eindhoven