Clinical trials: Cardiovascular Complications
Atrial Fibrillation, Atrial Flutter
Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis 2 (SAFE-D2)
People receiving dialysis are more likely to develop atrial fibrillation (AF), an irregular heartbeat that increases the risk of stroke.
- Conditions
- Atrial Fibrillation, Atrial Flutter, End Stage Kidney Disease (ESRD), Dialysis Patients
- Trial name
- SAFE-D2 (NCT07779746)
- Testing
- Eliquis, No oral anticoagulation
- Volunteers
- 848 people
- Sponsor
- Unity Health Toronto
Diabetes
Investigating Ultrasound Debridement in Wound Care
The initial step of wound management, debridement, is thought to be critical in promoting wound healing. Of the numerous debridement modalities, ultrasound seems to hold promising results in accelerate healing in our own clinical…
- Trial name
- NCT03516422
- Testing
- ULTRASOUND DEBRIDEMENT, STANDARD CARE GROUP
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Chronic Renal Failure
A Study of Cytokine and Inflammatory Markers in Patients With Chronic Renal Failure
We hope to study components within the blood that may predict success, failure or other associated complications in relation to the type of vascular access being used.
- Trial name
- NCT00565994
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Diabetic Foot
Repeated Educational Intervention for the Prevention of Diabetic Foot Ulcers in High-risk Patients
Following a prior observation that a brief structured group educational intervention is effective for the prevention of diabetic foot ulcers in high-risk patients, but that the efficacy decreases over the time, this study is…
- Trial name
- NCT03555656
- Testing
- Repeated intervention, Single session
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Turner Syndrome, Ovarian Insufficiency
Cryopreservation of Ovarian Cortex in Girls With Turner Syndrome
Ovarian insufficiency is common in Turner syndrome related to premature and rapid follicular apoptosis and spontaneous pregnancies are rare in this population.
- Trial name
- CRYO-X0 (NCT01410045)
- Testing
- Ovariectomy
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetic Foot - Telemedical Monitoring, Diabetic
Virtual Reality-Based 'Health at My Feet' Program for Individuals With Type 2 Diabetes
This randomized controlled experimental study aims to develop and evaluate the effectiveness of a Virtual Reality-Based "Health to My Foot" program designed for individuals with Type II Diabetes Mellitus.
- Conditions
- Diabetic Foot - Telemedical Monitoring, Diabetic, Foot Care, Virtual Reality
- Trial name
- NCT07473050
- Testing
- "Health for My Feet" virtual reality program.
- Volunteers
- 70 people
- Sponsor
- Ege University
Diabetic Foot Ulcers
A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)
The objective of this study is to evaluate the safety and efficacy of MEBO in the treatment of subjects with diabetic foot ulcers (DFUs).
- Trial name
- NCT01154374
- Testing
- MEBO Wound Ointment, Standard of Care (sterile saline moistened gauze)
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Skingenix, Inc.
Thyroid Pathology, Head and Neck Cancer (H&N)
FAPI PET Imaging - An Exploratory Study
This study is testing a new imaging tracer called [18F]FAPI-74 with PET scans. Researchers want to find out how well this tracer shows certain diseases in the body, including several types of cancer and some non-cancer conditions…
- Conditions
- Thyroid Pathology, Head and Neck Cancer (H&N), Sinonasal Tract Tumor, Sarcoidosis
- Trial name
- FAPIPET (NCT07705074)
- Testing
- [18F]FAPI-74 PET/CT
- Where
- 5 sites in Switzerland
- Volunteers
- 770 people
- Sponsor
- Martin Huellner
Hemodialysis, End-stage Renal Disease
Mechanisms and Treatment of Intradialytic Hypertension - Sodium
The purpose of this study is to determine the role of dialysate exposure and fluid removal during hemodialysis in the pathophysiology of intradialytic hypertension.
- Conditions
- Hemodialysis, End-stage Renal Disease, Hypertension, Intradialytic Hypertension
- Trial name
- MATCH-Sodium (NCT01371890)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetic Retinopathy
Progression of Diabetic Retinopathy. Identification of Signs and Surrogate Outcomes
Progression of Diabetic Retinopathy. Identification of Signs and Surrogate outcomes (PROGRESS)
- Trial name
- PROGRESS (NCT03010397)
- Where
- Portugal
- Volunteers
- 212 people
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Arrhythmia, Cardiac
Japanese Lead Extraction Registry
Japanese Lead Extraction (J-LEX) Registry is an observational nationwide registry, performed by Japanese Heart Rhythm Society, collaborated with the National Cerebral and Cardiovascular Center.
- Trial name
- J-LEX (NCT04345627)
- Where
- Japan
- Volunteers
- 5,000 people
- Sponsor
- National Cerebral and Cardiovascular Center, Japan
Diabetes Mellitus Foot Ulcer
Multifactorial Strategies for the Prevention of the Risks of Ulceration in Patients Affected by Diabetic Foot (DARE-DiaFoot)
This is a no-profit, multicentre, national, clinical trial for the prevention of the complications of the diabetic foot in two populations of patients with diabetes mellitus type-2.
- Trial name
- DARE-DiaFoot (NCT07021222)
- Testing
- Full Analysis, Partial Analysis
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Ortopedico Rizzoli
Polycystic Ovary Syndrome, Cardiovascular Disease
LIPT - Liraglutide in Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) affects 5-10% of women in fertile age. PCOS is associated with metabolic syndrom, diabetes and and increased risk og cardiovascular disease.
- Trial name
- LIPT (NCT02073929)
- Testing
- Liraglutide for 26 weeks
- Where
- 3 sites in Denmark
- Volunteers
- 72 people
- Sponsor
- Jens Faber
Kidney Disease, Chronic, Diabetes
Effect of SGLT2i on Cardiovascular Biomarkers in Patients With Type 2 Diabetes and CKD Stage 3b-4
This is a prospective, observational study to assess the effect of SGLT2 inhibitors on surrogate markers of kidney and cardiovascular health in patients with stage 3b and 4 chronic kidney disease (CKD).
- Trial name
- NCT05033054
- Testing
- SGLT2 inhibitor
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Texas Southwestern Medical Center
Covid19
Comorbidities and Risk Score in COVID-19 Patients
Retrospective multi-center cohort study. Consecutive patients hospitalized for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) up to October 2020 will be included.
- Trial name
- Comorbidities (NCT04670094)
- Where
- 5 sites in Italy
- Volunteers
- 4,555 people
- Sponsor
- University of Milano Bicocca
Diabetic Retinopathy
INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy Study
The central hypothesis is that inflammation mediators are biomarkers of both systemic diabetes and Diabetic Retinopathy (DR) progression in the aqueous and that sustained topical ketorolac application reduces/suppresses those…
- Trial name
- INSPIRE (NCT04505566)
- Testing
- Ketorolac 0.45% ophthalmic solution, Aqueous PGE2 and inflammatory cytokines measurements
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Stephen J. Kim, MD
Diabetes, Cardiovascular Diseases
The Manitoba Personalized Lifestyle Research (TMPLR) Study
Lifestyle factors, such as diet, physical activity and sleep, are associated with the development of many chronic diseases. The objective of The Manitoba Personalized Lifestyle Research (TMPLR) study is to understand how these…
- Conditions
- Diabetes, Cardiovascular Diseases, Chronic Kidney Diseases
- Trial name
- NCT03674957
- Where
- Canada
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Kidney Failure, Chronic, Diabetic Nephropathies
Effects of Rituximab and Mycophenolate Mofetil (MMF) on Highly Sensitized Patients Awaiting Renal Transplant
This is a 12-month phase 2, prospective, open label study to evaluate the effect of rituximab with mycophenolate mofetil (MMF)on the PRA of 14 highly sensitized patients who just completed an 8 month trial of MMF treatment alone.
- Conditions
- Kidney Failure, Chronic, Diabetic Nephropathies, Glomerulonephritis, IGA, Hypertension, Renal
- Trial name
- NCT00446251
- Testing
- Rituximab, Mycophenolate mofetil (MMF)
- Volunteers
- 14 people
- Sponsor
- University of Washington
Hypertension, Renal Stone
A Study to Investigate the Effect of Extracorporeal Shockwave Lithotripsy on Hypertension
Having the advantages of being minimally invasive and simple, extracorporeal shock wave lithotripsy (SWL) remains one of the treatment options for renal stones less than 2cm.
- Trial name
- NCT03714477
- Testing
- Extracorporeal shock wave lithotripsy
- Where
- Hong Kong
- Sponsor
- Chinese University of Hong Kong
ANCA Associated Vasculitis
Multicenter Cohort Study of AAV in Hunan of China
This study aimed to explore the incidence of Anti-neutrophil cytoplasmic antibody (ANCA）-associated vasculitis (AAV) progression and its association with adverse consequences.
- Trial name
- NCT05315141
- Testing
- No Intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xiangya Hospital of Central South University
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