Clinical trials: Cardiovascular Condition
Left Ventricular Systolic Dysfunction
3D & Speckle Tracking Together as a Marker for Early Outcome in Cardiac Surgery
Patients presenting with Left Ventricle (LV) dysfunction undergoing cardiac surgery are at increased risk of perioperative morbidity and mortality.
- Trial name
- NCT02642770
- Testing
- Transesophageal echocardiography
- Where
- India
- Volunteers
- 73 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Atrial Fibrillation
Non-invasive Quantification of Atrial Fibrosis by MRI in Atrial Fibrillation
Three groups of patients will be considered: a control group (n = 10); a group of patients with paroxysmal or persistent AF with AF cryoablation procedure - within this group, MRI will replace CT-scan usually performed in routine…
- Trial name
- QUAFI (NCT02885883)
- Testing
- MRI 3T
- Where
- France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Wounds, Wound of Skin
A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.
The goal of this clinical trial is to follow the progress of wounds in those with venous leg ulcers and diabetic foot ulcers while using an absorbent dressing called Mepilex Up.
- Conditions
- Wounds, Wound of Skin, Wound Leg, Wound; Foot
- Trial name
- NCT05588583
- Testing
- Mepilex Up
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- Molnlycke Health Care AB
Stroke
Stroke Upper Limb Rehabilitation With Robot Operators: a Synergistic Approach for Human-Robot Interaction and Rehabilitative Trials.
In clinical scenario, clinical scales and kinematic analysis are usually used for the evaluation of patients. However, these methods are limited, since they may suffer from the lack of objectivity and sensitivity.
- Trial name
- SULLRO (NCT07768683)
- Testing
- Upper Limb robotic training
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Villa Beretta Rehabilitation Center
Atrial Fibrillation, Atrial Flutter
Suture Closure AFtEr VEIN Access for Cardiac Procedures (SAFE-VEIN) Trial
Primary objective: To compare the safety and efficacy of closure strategies post venous access procedures. Hypothesis: We anticipate that the use of a venous closure device will decrease the time to hemostasis (TTH), time to…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Heart Block, Pulmonary Embolism and Thrombosis
- Trial name
- SAFE-VEIN (NCT04632641)
- Testing
- Perclose ProGlide Suture-Mediated Closure System (SMC) - LARGE-BORE PROCEDURES, Figure 8 Suture - LARGE-BORE PROCEDURES
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Wake Forest University Health Sciences
Peripheral Arterial Disease
Momentum-enabled Treadling Methodology to Improve Gait and Enhance Mobility
This is a pilot study of a new exercise device (TREDLR) designed to facilitate repetitive ankle flexion/extension movements (i.e., "treadling") through a momentum-driven internal flywheel while seated.
- Trial name
- NCT03891641
- Testing
- Treadwell Tredlr
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of North Carolina, Chapel Hill
Stroke
The Effect of Inspiratory Exercises on Diaphragm and Intercostal Muscle Thickness in Stroke Patients
The aim of this study is to investigate the effect of inspiratory muscle strengthening exercises on bilateral parasternal intercostal muscle thickness and bilateral diaphragm muscle thickness in stroke patients and to present new…
- Trial name
- NCT07206641
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Marmara University
Stroke
The Fall Monty Activity Programme Feasibility Study
Between 45-73% of people who have had a stroke fall over in the months and years following their stroke. Falls not only lead to injuries such as broken hips, but they may also lead to fear of falling.
- Trial name
- FallMAP (NCT03484351)
- Testing
- Fall Monty Activity Programme (FallMAP)
- Where
- Australia
- Volunteers
- 5 people
- Sponsor
- Curtin University
Aortic Stenosis, Atrial Fibrillation New Onset
Long Term Evaluation of Cardiac Arrhythmias After Transcatheter Aortic Valve Implantation -The LOCATE Registry
The purpose of the Long term Evaluation of Cardiac Arrhythmias after Transcatheter Aortic Valve Implantation (LOCATE) Registry is to perform long-term ambulatory monitoring of patients with severe aortic stenosis who undergo…
- Conditions
- Aortic Stenosis, Atrial Fibrillation New Onset, Heart Block
- Trial name
- NCT06055751
- Testing
- TAVR Procedure and implantation of Boston Scientific Loop Recorder (LUX-Dx PMA# K193473)
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Ischemic Stroke
Remote Ischemic Conditioning for Motor Recovery After Acute Ischemic Stroke
The most recent treatment for stroke rehabilitation is to combine physical training with other therapies to enhance or accelerate recovery.The hypothesis of this study is that remote ischemic conditioning (RIC) might have a…
- Trial name
- NCT05263531
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ji Xunming,MD,PhD
Alagille Syndrome
Characterization of Pulmonary Artery Stenoses in Alagille Syndrome - a Medical Record Review
Patients who have Alagille Syndrome (AGS) also frequently have blockages (or "stenoses") of their pulmonary arteries. Little is known about the degree or variability of these stenoses, or the effect of this disease on the right…
- Trial name
- NCT01515631
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Pulmonary Embolism
Catheter Thrombectomy in Patients With Massive Pulmonary Embolism
Official Title: Compassionate Use of Catheter Thrombectomy (Aspirex 11F) in Patients With Massive Pulmonary Embolism Study Population: Patients >/= 18 years of age with massive pulmonary embolism suitable for mechanical…
- Trial name
- NCT00314002
- Testing
- Mechanical Thrombectomy
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 50 people
- Sponsor
- Straub Medical AG
Atrial Fibrillation
Safety and Effectiveness of Low Dose Edoxaban in Patients With NVAF
The efficacy and safety of edoxaban has not been adequately studied in Asians versus non-Asians, who are quite different physiologically from each other.
- Trial name
- LEDIOS (NCT03554837)
- Where
- South Korea
- Volunteers
- 2,562 people
- Sponsor
- Samsung Medical Center
Hypertension, Renal Insufficiency
Food Frequency Questionnaire to Assess Sodium Intake
EvalSel can precisely assess the salt intake of hospitalized patients in nephrology and cardiology or in medical consultation. It can determine salt consumption to the nearest gram.
- Trial name
- EVALSEL (NCT05533645)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Lille
Pain, Acute, Congenital Heart Disease
Transverse Thoracic Plane Block in the Pediatric Cardiac Patient
Postoperative pain after cardiothoracic surgery can be a significant problem interfering with recovery, yet difficult to manage due to the sedating effects of opiates.
- Trial name
- TTPPCT (NCT04138745)
- Testing
- Transverse Thoracic Plane Block
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Heart Failure, Diastolic Heart Failure
Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF
This study will be performed to determine the safety, tolerability, and dose-response to inorganic nitrate on exercise capacity in HFpEF. There are two primary goals for this study: 1.
- Trial name
- NCT02256345
- Testing
- KNO3, KCl
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Pennsylvania
Coronary Artery Disease
Effectiveness of Clopidogrel Resinate in PCI(PRIDE)
This study is an open label, multi-center, randomized trial, which is designed to evaluate the efficacy and safety of clopidogrel derivative (Pregrel®) therapy for 12 months in patients undergoing PCI compared to conventional…
- Trial name
- NCT01349777
- Testing
- Pregrel®, Plavix®
- Where
- 3 sites in South Korea
- Volunteers
- 1,056 people
- Sponsor
- Seung-Jung Park
Neurodevelopmental Disorders, Congenital Heart Disease
Altered Cerebral Growth and Development in Infants With Congenital Heart Disease
Background: Congenital heart disease (CHD) is the most frequent inborn defect with an incidence of 1 in 100 newborns per year, i.e. 800 children born in Switzerland per year.
- Conditions
- Neurodevelopmental Disorders, Congenital Heart Disease, Brain Injuries, Fetal Growth Retardation
- Trial name
- NCT04233775
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Dyslipidemias, Acute Coronary Syndrome
North American Acute Coronary Syndrome (ACS) Reflective III Pilot
The North American ACS Reflective III Pilot is an observational, Quality Enhancement Research Initiative (QuERI), knowledge translation program designed to give feedback to physicians on their post-ACS lipid-lowering management…
- Trial name
- NCT03994575
- Testing
- Guideline recommended feedback
- Where
- Canada
- Volunteers
- 248 people
- Sponsor
- Canadian Heart Research Centre
Ischemic Stroke
Different Treatment Strategies on Prognosis of Acute Ischemic Stroke(AISDTS)
AISDTS is a prospective registry study, in which clinical information, examination and imaging data of patients with acute ischemic stroke receiving different treatment strategies were collected, grouped and statistically…
- Trial name
- NCT05410457
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
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