Clinical trials: Cardiovascular Disease, Obesity
Overweight and Obesity, Vitamin D Deficiency
Magnesium and Vitamin D Supplementation and Cardiometabolic Outcomes
The purpose of this study is to investigate the effects of a combined vitamin D and magnesium supplementation on parathyroid hormone and cardiometabolic health in persons living with obesity.
- Conditions
- Overweight and Obesity, Vitamin D Deficiency, Magnesium Deficiency, Cardiovascular Risk Factor
- Trial name
- NCT03134417
- Testing
- Vitamin D and magnesium, Vitamin D
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Drexel University
Cardiovascular Diseases, Heart Diseases
Hypertension in Blacks of West African Origin
To continue an international collaborative study on hypertension in populations of West African origin.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Obesity
- Trial name
- NCT00005340
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Venous Thromboembolism, Obese Patients
Evaluation of Anti-Xa Activity in Patients With Severe Obesity After Subcutaneous Injection of Enoxaparin for Antithrombotic Prophylaxis at Two Different Sites.
To evaluate appropriateness of enoxaparin bioavailability at two different sites of subcutaneous administration (arms or abdomen) in primary or secondary prevention of thromboembolism in a population of patients with severe…
- Trial name
- EPOS (NCT07213713)
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Acute Kidney Injury, Arterial Hypertension
Study Evaluating Novel Biomarkers of AKI (Acute Kidney Injury) in Post-operative Patients
To validate the use of [TIMP-2]●[IGFBP-7] to predict AKI in patients undergoing major intra abdominal surgery.
- Conditions
- Acute Kidney Injury, Arterial Hypertension, Obesity, Cardio Vascular Disease
- Trial name
- NCT02499185
- Testing
- Nephro Check Test, serum creatinine measurement
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Obese, Sleep Apnea, Obstructive
Nutritional Rehabilitation and Sleep Apnea in the Obese
In obese patients, the prevalence of obstructive sleep apnea (OSA) is around 40% in men and 30% in women. Weight loss after bariatric surgery significantly improves OSA, with 75% of patients having a reduction in OSA severity or…
- Trial name
- DIETSLEEP (NCT03857191)
- Testing
- Nutritional psychocomportemental rehabilitation
- Where
- France
- Volunteers
- 396 people
- Sponsor
- University Hospital, Grenoble
Anxiety, Wellness, Psychological
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes.
- Conditions
- Anxiety, Wellness, Psychological, Overweight or Obesity, Hypertension
- Trial name
- F2L (NCT06596265)
- Testing
- Fit2Lead Group 1-2
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Brain Care Score, Exercise
An Exercise Intervention to Improve Overall Brain Health
The goal of this clinical trial is to test the effects of 10 weeks of exercise on overall brain health, reduction in blood pressure, and the number of blood vessels in the back of the eyes in patients with hypertension and have a…
- Conditions
- Brain Care Score, Exercise, Hypertension, BMI
- Trial name
- NCT06035094
- Testing
- Exercise Intervention to improve overall Brain Health
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hypertension, Pre Hypertension
Electronic Health Record-Based Clinical Decision Support to Improve Blood Pressure Management in Adolescents
The goal of this project is to improve detection and management of elevated blood pressure in adolescents. It (a) uses electronic health record (EHR) technology to deliver patient-specific clinical decision support (CDS) to…
- Conditions
- Hypertension, Pre Hypertension, Obesity
- Trial name
- NCT01760239
- Testing
- Clinical Decision Support (CDS)
- Where
- United States
- Volunteers
- 31,579 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Psoriasis, Obesity
Cross-sectional Evaluation of Biological Markers of Cardiovascular Disease in Children and Adolescents With Psoriasis
Hypothesis 1: Patients with psoriasis will have clinical and laboratory assessments differing from control patients. Hypothesis 2: Patients with psoriasis will have laboratory alterations that correlate with other clinical…
- Conditions
- Psoriasis, Obesity, Cardiovascular Risk, Inflammation
- Trial name
- NCT01122095
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Cardiovascular Diseases, Heart Diseases
Biobehavioral Determinants of Obesity in Black Women
To examine the biobehavioral determinants of obesity in Black as compared with white women.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Telangiectasis
- Trial name
- NCT00005386
- Sponsor
- University of Memphis
Hypertension, Type2diabetes
Nutrition Outreach and Understanding: Research In Serving Hearts Through Healthy Eating And Tailored Support
This study is a human-centered, three-arm, parallel-group, randomized control, implementation trial (n=75) to compare MTM (Medically Tailored Meals) only (14 meals delivered weekly for 10 weeks) vs.
- Conditions
- Hypertension, Type2diabetes, Metabolic Syndrome, Obesity
- Trial name
- NOURISH HEARTS (NCT06460272)
- Testing
- Medically Tailored Meals
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Amanda Shallcross
Obesity, Healthy
Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity
Patients with sleep apnea are at increased risk of developing cardiovascular disease - with women at potentially greater risk than men.
- Conditions
- Obesity, Healthy, Vasoconstriction, Vasodilation
- Trial name
- NCT04436731
- Testing
- Cold Pressor Test
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity &Amp; Overweight, Hypertension
A Prospective Randomnised Controlled Trial Comparing Overall Patient Compliance in a Bariatric Surgical Pathway Using the Standard Versus a More Intensified and Interactive Version of the "Get Ready" Smartphone Application.
The aim of this study is to assess the impact of a newly intensified digital platform following bariatric surgery. This will be measured using several questionnaires.
- Conditions
- Obesity &Amp; Overweight, Hypertension, Obstructive Sleep Apnea (OSAS), Diabetes Mellitus ( Type 1 and Type 2)
- Trial name
- NCT07297342
- Testing
- GetReady application, Intensified GetReady application
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Sint Dimpna Ziekenhuis Geel
Obesity
A Study on Efficacy and Safety of Topiramate in Maintaining Weight Loss in Obese Patients Following an Intensive, Non-Pharmacologic Weight Loss Program
The purpose of this study is to compare the efficacy and safety of topiramate 96mg and 192mg daily) with placebo in the treatment of obesity following an intensive non-pharmacologic weight loss program.
- Trial name
- NCT00236600
- Testing
- topiramate
- Volunteers
- 561 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Obesity & Overweight, Perimenopausal Women
Prebiotic Inulin for Late-Reproductive Individuals
This study aims to evaluate the effects of 2 weeks of inulin supplementation in perimenopausal women with overweight or obesity. The primary questions this study seeks to answer are: 1.
- Conditions
- Obesity & Overweight, Perimenopausal Women, Prebiotics, Inulin
- Trial name
- PILI (NCT07724522)
- Testing
- Inulin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- George Washington University
Insulin Resistance, Atherosclerosis
The Effect of Cranberry Extract Supplementation on Cardiovascular Risk Factors in Obese, Insulin Resistant Humans
The purpose of this study is to determine the health benefits of cranberry extract in people who are at risk for diabetes and heart problems.
- Trial name
- NCT02068144
- Testing
- Cranberry Extract
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Atherosclerosis
A Study on Intima Media Thickness (IMT) in Middle-aged Subjects
This is an observational study to measure the thickness of artery walls in the neck (intima media thickness IMT) by ultrasound examination in middle-aged subjects with central obesity.
- Trial name
- IMT (NCT00784264)
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- AstraZeneca
Cardiovascular Disease, Metabolic Syndrome
Absorption and Antioxidant Effects of Polyphenolics From Acai
A human clinical consumption trial will be performed in volunteers with increased risk factors for cardiovascular disease (Metabolic Syndrome), which includes obesity and diabetes and related conditions over a period of 12 weeks…
- Conditions
- Cardiovascular Disease, Metabolic Syndrome, Obesity
- Trial name
- NCT02227628
- Testing
- Acai polyphenolics, Sugary Beverage
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Obesity
Clinical Observation of Implementing the MedGem Into a Medical Specialty Practice
Due to common CVD diseases associated from obesity, medical providers are in a position to provide assistance. However, less than 10% of all patients receive any weight loss advice from physicians.
- Trial name
- NCT00489502
- Testing
- Brief Counseling, REE Assessment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Microlife
Cardiovascular Diseases, Heart Diseases
Genetics of CVD Risk Factors in Samoans
To evaluate the role of known genes involved in lipid metabolism on serum lipid and apolipoprotein levels in Samoans residing in American and Western Samoa, who were exposed to the biobehavioral changes of modernization.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Atherosclerosis
- Trial name
- NCT00005528
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
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