Clinical trials: Cardiovascular Disease, Obesity
Gestational Diabetes Mellitus in Pregnancy, Gestational Hypertension
No-worry Baby Project
The Huizhou mother-infant cohort was set up to investigate the effect of dietary factors and environmental exposures during pregnancy on health consequences of mothers and offsprings in Huizhou, China.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Gestational Hypertension, Thyroid Disease Pregnancy, Obesity
- Trial name
- NCT03922087
- Testing
- No intervention
- Where
- China
- Volunteers
- 5,216 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Overweight, Hyperlipidemia
The Effect of Switching to Aripiprazole on Heart Health in Overweight and Obese Patients With Schizophrenia
This is a 2-year study proposing to examine the effects of aripiprazole on heart health factors such as serum lipids, serum leptin, fasting blood sugar, body weight and blood pressure.
- Conditions
- Overweight, Hyperlipidemia, Cardiovascular Diseases
- Trial name
- NCT00222833
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Blood Pressure, Obesity
Blood Pressure Changes After Bariatric Surgery
The aim of the study is to assess changes in blood pressure, cardiac function and selected laboratory measurements after bariatric surgery and to find most important factors associated with blood pressure reduction after weight…
- Conditions
- Blood Pressure, Obesity, Bariatric Surgery, Hypertension
- Trial name
- NCT06460233
- Testing
- Bariatric surgery - sleeve gastrectomy
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Obesity, Hypertension
The Effects of Metformin on Blood Vessel Structure and Function
The purpose of this study is to evaluate whether the drug Metformin has beneficial effects on the blood vessels of individuals with the Metabolic Syndrome (MeS).
- Conditions
- Obesity, Hypertension, Hypercholesterolemia, Hyperglycemia
- Trial name
- NCT00105066
- Testing
- Metformin
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- National Institute on Aging (NIA)
Cardiovascular Diseases, Infant ALL
Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH)
This pilot study aims to examine the feasibility and acceptability of adding a cardiovascular health module to the existing Nurse Family Partnership (NFP) home visitation program delivered by trained nurses in the Northern…
- Conditions
- Cardiovascular Diseases, Infant ALL, Maternal Behavior, Childhood Obesity
- Trial name
- ENRICH (NCT05824741)
- Testing
- Infant Cardiovascular Health (CVH) Promotion
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity, Hypertension
Supermarket and Web-Based Intervention Targeting Nutrition (SuperWIN) for Cardiovascular Risk Reduction
The Supermarket and Web-based Intervention targeting Nutrition (SuperWIN) for cardiovascular risk reduction is a novel, randomized controlled trial aimed at increasing diet quality and decreasing cardiovascular risk.
- Conditions
- Obesity, Hypertension, Hyperlipidemias, Diet Modification
- Trial name
- SuperWIN (NCT03895580)
- Testing
- In-store POP education, Online POP education
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- University of Cincinnati
Metabolic Syndrome (MetS), Hypertension (HTN)
Metabolic Surgery for Metabolic Syndrome
This study is designed to understand how bariatric surgery affects patients with metabolic syndrome over both the short and long term.
- Conditions
- Metabolic Syndrome (MetS), Hypertension (HTN), Obesity, T2
- Trial name
- NCT07183137
- Where
- 3 sites in China
- Volunteers
- 1,581 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Obesity, Hypertension
Blood Pressure and Weight Trajectory on a Dual Antihypertensive Combination Plus Sibutramine Versus Placebo in Obese Hypertensives
To study the effect of sibutramine treatment on weight reduction and blood pressure improvement in three groups with antihypertensive therapy whose blood pressure was not adequately controlled with antihypertensive combination…
- Trial name
- HOS (NCT00679653)
- Testing
- sibutramine, verapamil/trandolapril, metoprolol/HCT
- Volunteers
- 171 people
- Sponsor
- Abbott
Body Weight, Obesity
Meta Analysis of the Effect of a Low Glycemic Index Diet and Glycemic Load on Body Weight
A low glycemic index (GI) diet has been associated with improved glycemic control in type 2 diabetes patients and a reduced risk of cardiovascular disease (CVD).
- Conditions
- Body Weight, Obesity, Cardiovascular Diseases, Diabetes Mellitus, Type 2
- Trial name
- NCT02557022
- Testing
- GI and/or GL
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Prediabetes, Hypertension
Fasting Predictors of OGTT and MMTT Response
1. To develop a database containing matched information from dynamic tests of postprandial glycemic control (OGTT or MMTT), results of a broad panel of fasting biomarkers, and clinical information related to diabetes risk obtain…
- Conditions
- Prediabetes, Hypertension, Obesity, Cardiovascular Disease
- Trial name
- NCT01998867
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Health Diagnostic Laboratory, Inc.
Obesity, Metabolic Syndrome
Milk Types and Fish Oil in 9- to 12-Month-Old Infants
The objective of this intervention study is to examine the effect of whole cow's milk versus infant formula as primary milk sources with or without supplements of n-3 LCPUFA for growth, nutritional status, development, risk…
- Conditions
- Obesity, Metabolic Syndrome, Growth, Blood Pressure
- Trial name
- NCT00379171
- Testing
- Cow's milk with fish oil, Cow's milk without fish oil, Formula with fish oil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diet, Healthy, Diabetes Mellitus
The Impact of Chokeberry Bioproducts on Metabolic Parameters and Antioxidant Potential
Chokeberry can be used both in the prevention and treatment of various metabolic disorders due to its high antioxidant properties.
- Conditions
- Diet, Healthy, Diabetes Mellitus, Hypertension, Obesity
- Trial name
- NCT06435130
- Testing
- Dietary intervention with chokeberry juices, Dietary intervention with chokeberry juices and fibers
- Where
- Poland
- Volunteers
- 102 people
- Sponsor
- Medical University of Bialystok
Cardiometabolic Syndrome, Physical Inactivity
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8…
- Conditions
- Cardiometabolic Syndrome, Physical Inactivity, Hypertension, Type 2 Diabetes
- Trial name
- NCT06055036
- Testing
- Black Impact Intervention
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- Ohio State University
Cardiovascular Risk Factors
Cocoa Extract-enriched Meals and Cardiovascular Risk in Older Population
Obesity prevalence in elderly populations has increased in the last years, and the reduction of overweight and obesity is a priority target in populations of all age ranges worldwide.
- Trial name
- NCT01596309
- Testing
- Cocoa extract
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Pre-Eclampsia, Obesity
Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women
The purpose of this study is to conduct a pilot randomized controlled trial of a food is medicine community health worker intervention called the Women's Health Delaware Food Farmacy compared to the usual standard of care among…
- Conditions
- Pre-Eclampsia, Obesity, Gestational Diabetes, Gestational Hypertension
- Trial name
- NCT06180811
- Testing
- Women's Health Delaware Food Farmacy, Usual Standard of Care
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Christiana Care Health Services
Type 2 Diabetes Mellitus (T2DM), Atrial Fibrillation (AF)
Strict Weight Management Based on GLP-1 RA for Ablation Outcomes in Overweight or Obese Patients with T2DM and AF
Objective To compare, in patients with Type 2 Diabetes Mellitus (T2DM) and Atrial Fibrillation (AF) undergoing radiofrequency ablation (RFA), whether strict weight management and glycemic control based on Glucagon-like Peptide-1…
- Trial name
- NCT06660134
- Testing
- Glucagon-like peptide-1 receptor agonists (GLP 1 RA)
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Shanghai Chest Hospital
Cognitive Impairment, Dementia
Determinants of Cognitive Impairment Among Geriatrics
This study aims to explore the determinants of cognitive impairment among Indonesian geriatrics in an Old Age Home.
- Conditions
- Cognitive Impairment, Dementia, Hearing Impairment, Vision Impairment and Blindness
- Trial name
- NCT03669536
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Obesity, Diabetes
Translating the Diabetes Prevention Program Into a Virtual Lifestyle Management Program
The objective of this study is to evaluate the effectiveness of Virtual Lifestyle Management (VLM) as a behavior modification tool to promote weight loss, healthy eating and physical activity patterns, in the interest of reducing…
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT00867425
- Testing
- Virtual Lifestyle Management
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Vascular Disease
Manchester Antenatal Vascular Service
25-30% of women with preexisting vascular disease (chronic hypertension/diabetes/obesity) will develop pre-eclampsia and or growth restriction.
- Trial name
- MAViS (NCT02244385)
- Testing
- no intervention
- Where
- United Kingdom
- Volunteers
- 750 people
- Sponsor
- Manchester University NHS Foundation Trust
Heart Failure With Preserved Ejection Fraction
Prediction of the Development of Heart Failure With Preserved Ejection Fraction
The ultimate goal of the PREDICT-HFpEF study is to identify and unravel predictors for the development of heart failure with preserved ejection fraction (HFpEF) in a cohort at increased cardiovascular risk.
- Trial name
- PREDICT-HFpEF (NCT04894968)
- Testing
- Assessment of the presence of heart failure with preserved ejection fraction, according to guideline recommendations from the European Society of Cardiology 2016
- Where
- Germany
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Heart Center Leipzig - University Hospital
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