Clinical trials: Cardiovascular Disease, Obesity
Hypertension, Obesity
Kagoshima Collaborate Trial in Metabolic Syndrome (KACT Study)
The purpose of this study is to consider the following points in patients with hypertension who complicated by metabolic syndrome for Valsartan basis treatment and an existing, standard treatment.
- Trial name
- KACT (NCT00790946)
- Testing
- Valsartan
- Where
- Japan
- Volunteers
- 250 people
- Sponsor
- Kagoshima University
Obesity
Real-World Evidence on the Cardiovascular Safety of CONTRAVE® in the United States (U.S.)
The fixed-dose combination of naltrexone 8mg and bupropion 90mg extended-release oral tablet is marketed under the trade name CONTRAVE® in the U.S.
- Trial name
- HOA (NCT06090461)
- Where
- United States
- Volunteers
- 31,889 people
- Sponsor
- Currax Pharmaceuticals
Obesity, Hypertension
Feasibility of Integrating Indirect Calorimetry (IC) Technology in Primary Care
The purpose of this study is to evaluate the feasibility of using indirect calorimetry (IC) within a comprehensive weight reduction program.
- Trial name
- NCT00750022
- Testing
- Individualized IC treatment, Usual Care
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Chronic Care Innovations, Inc.
Obesity, Overweight
Vitamin D Supplementation for the Prevention of Cardiovascular Risk
Hypovitaminosis D is highly prevalent in the general population, particularly in obese individuals. Besides being associated with obesity, vitamin D deficiency seems to be involved in the pathogenesis of insulin resistance and…
- Conditions
- Obesity, Overweight, Insulin Resistance
- Trial name
- NCT02020694
- Testing
- Vitamin D
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Mood Disorders, Hypertension
Association of Mood With Risk for Atherosclerosis
The investigators will aim to determine the association of mood disorders (MDO) with preclinical and clinical cardiovascular (CVD) risk factors among children.
- Conditions
- Mood Disorders, Hypertension, Overweight and Obesity, Vascular Stiffness
- Trial name
- AuRA (NCT04298944)
- Testing
- Cardiovascular Assessments, Actigraphy, Laboratory assessments
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Johns Hopkins University
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diet, Healthy, Diabetes Mellitus
The Impact of Chokeberry Bioproducts on Metabolic Parameters and Antioxidant Potential
Chokeberry can be used both in the prevention and treatment of various metabolic disorders due to its high antioxidant properties.
- Conditions
- Diet, Healthy, Diabetes Mellitus, Hypertension, Obesity
- Trial name
- NCT06435130
- Testing
- Dietary intervention with chokeberry juices, Dietary intervention with chokeberry juices and fibers
- Where
- Poland
- Volunteers
- 102 people
- Sponsor
- Medical University of Bialystok
Cardiovascular Diseases, Heart Diseases
Physical Training and Blood Pressure in High Risk Youths
To determine the effects of physical activity on blood pressure and body fat in children varying in ethnicity, gender, and health status.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Obesity
- Trial name
- NCT00005695
- Sponsor
- Augusta University
Insulin Resistance, Obesity
Integrating the Genetic and Metabolic Faces of Obesity
The goal of this study is to determine why some obese individuals develop insulin resistance and others do not. We hypothesize that an impairment in differentiation of fat cells (adipocytes) is responsible for the development of…
- Conditions
- Insulin Resistance, Obesity, Metabolic Syndrome
- Trial name
- NCT00285844
- Testing
- weight loss, thiazolidinedione
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Morbid, Hypertension
Antibiotics, Gastric Bypass, and the Microbiome
This study randomizes patients to two commonly used peri-procedural antibiotics after gastric bypass with the pre and post-operative collection of stool samples, to identify significant differences in relative abundances of gut…
- Conditions
- Obesity, Morbid, Hypertension, Bariatric Surgery Candidate
- Trial name
- NCT05367479
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Medical College of Wisconsin
Type 2 Diabetes, NAFLD
Diabetes Nutrition Algorithms in Patients With Overt Diabetes Mellitus
Basic treatment of type 2 diabetes should focus on diet, physical activity and lifestyle. Nevertheless, in early and late stage of T2DM, lifestyle intervention is mostly substituted by pharmacological intervention, although…
- Conditions
- Type 2 Diabetes, NAFLD, Obesity, Dyslipoproteinaemia
- Trial name
- DiNA-D (NCT02459496)
- Testing
- dietary consulting and advise
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- German Institute of Human Nutrition
Cardiac Disease, Cardiovascular Diseases
Cardiometabolic Risk Factors and Processed Food
Cardiovascular diseases (CVD) remain a primary cause of chronic disability and mortality globally, with cardiometabolic risk factors such as hypertension, dyslipidemia, obesity, and diabetes significantly contributing to their…
- Conditions
- Cardiac Disease, Cardiovascular Diseases, Nutrition, Nutritional Disease
- Trial name
- NCT06996262
- Testing
- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Healthy, Diabetes Type 2
Assessment of Three Instruments for the Non-invasive Measurement of Arterial Stiffness.
The ASI Non-Invasive Arterial Stiffness Screening Device (ASI Device) is an investigational device under development for the non-invasive assessment of arterial stiffness.
- Conditions
- Healthy, Diabetes Type 2, Obesity, Coronary Artery Disease
- Trial name
- ASI-2012 (NCT01722474)
- Testing
- ASI Device
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obesity, Overweight
MOVE OUT: A Partnership With Veterans Groups to Enhance Weight Management in the Veterans Health Administration (VHA)
Obesity has been linked to several serious medical conditions, including high blood pressure, diabetes, and poor cholesterol levels.
- Conditions
- Obesity, Overweight, Hypertension, Diabetes Mellitus
- Trial name
- NCT01339390
- Testing
- MOVE OUT, MOVE!
- Where
- United States
- Volunteers
- 3,169 people
- Sponsor
- VA Office of Research and Development
Obesity, Type D Personality
The Stress-release Effects of Exercise in Obese Are Determined by DS14 Score and T-cell Activation Status
The purpose of the study was to analyze negative affectivity (NA) and social inhibition (SI) inquired by DS14 score in type D personality (distressed personality) to the relation of autonomic regulation of heart function (HRV)…
- Conditions
- Obesity, Type D Personality, Coronary Heart Disease
- Trial name
- NCT02493413
- Volunteers
- 30 people
- Sponsor
- Institute for Preventive Medicine, Trzaska
Cardiometabolic Risk Factors, Diabetes
Delta GREENS Food is Medicine Intervention
Mississippi is a place deeply rooted in cultural values, yet also a place where generations of communities have experienced persistent health challenges intertwined with poverty.
- Conditions
- Cardiometabolic Risk Factors, Diabetes, High Blood Pressure, Obesity
- Trial name
- NCT06358859
- Testing
- Food is Medicine
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tufts University
Heart Failure, Diabetes Mellitus
Effects of a High Protein Diet on Clinical Outcomes in Heart Failure
This research project was designed to study the role of dietary modifications in heart failure (HF) patients that suffer from type 2 diabetes mellitus and obesity.
- Trial name
- NCT01423266
- Testing
- 12-week supervised weight loss intervention
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of California, Irvine
Dietary Habits, Inflammation
Economic Crisis and Adherence to the Mediterranean Diet (CASSIOPEA)
The socioeconomic gradient in health is well known and is partially explained by differences in health-related behaviours across socioeconomic groups.
- Conditions
- Dietary Habits, Inflammation, Economic Problems, Obesity
- Trial name
- CASSIOPEA (NCT03119142)
- Where
- Italy
- Volunteers
- 3,646 people
- Sponsor
- Neuromed IRCCS
Hypertension, Atherosclerosis
Age-Related Changes in Body Composition
Background: Advancing age is associated with greater risk of heart disease. High blood pressure and hardening of the arteries also have more complications with age.
- Trial name
- NCT01517113
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Atrial Fibrillation, Obesity
Association of Obesity and Cardiovascular Outcomes in Atrial Fibrillation
In this study, the investigators evaluated the association between various measures of adiposity [BMI and waist circumference (WC)] and clinical outcomes in Asian patients with AF who were prescribed OAC, using a nationwide…
- Conditions
- Atrial Fibrillation, Obesity, Prognosis, Anticoagulants
- Trial name
- Paradox (NCT05645913)
- Testing
- Oral anticoagulant
- Where
- South Korea
- Volunteers
- 56,272 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
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