Clinical trials: Cardiovascular Disease, Obesity
Hypertension, Obesity
The Effect of Oral SPM Supplementation on INflammation-induced Vascular Ageing in Obese Hypertensive Patients
Cardiovascular risk factors such as obesity, diabetes, high blood pressure, high cholesterol, or smoking are associated with an increased risk of events such as myocardial infarction, stroke, or peripheral artery disease.
- Trial name
- SPIN-VA (NCT07038252)
- Testing
- Oral SPM-enriched marine oil (LIPINOVA)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 2, Obesity
Effect of Dairy Consumption on Glycemic Control, Body Weight and Cardiovascular Risk Factors
The aim of this study is to determine the relationship between the percentage of calories from dairy intake and long-term glycemic control and weight maintenance in patients with type 2 diabetes who participate in an intensive…
- Trial name
- NCT02896140
- Testing
- Type 2 diabetes in WhyWAIT Program
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Joslin Diabetes Center
Obesity
Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention
In Protocol #2, we will select 30 obese pubertal and 30 obese prepubertal subjects with an abnormal cytokine profile (i.e. fibrinogen and/or hsCRP concentration greater than or equal to 2 Standard Deviations (SD) above the mean…
- Trial name
- NCT00139477
- Testing
- Metformin, Dietary modification with caloric restriction, Establishment of exercise protocol
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Variation of Genes Controlling Carbohydrate and Lipid Metabolism
Aim of the study is to investigate genes regulating glucose and lipid metabolism in subjects whose glucose metabolism, lipid metabolism, blood flow, or body fat distribution has been measured using positron emission tomography…
- Conditions
- Diabetes Mellitus, Type 2, Cardiovascular Diseases, Obesity, Insulin Resistance
- Trial name
- CMgene (NCT03310502)
- Where
- Finland
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Severe Coronary Artery Disease, Obesity
Chronic Inflammatory Activation in Fat Tissue: An Atherogenic Factor in Severe Coronary Artery Disease
Chronic inflammatory activation in fat tissue can be the link between adiposity and an increased risk for atherosclerosis. The aim of this study is to investigate how molecular alterations in fat tissue can be influenced by…
- Conditions
- Severe Coronary Artery Disease, Obesity, Impaired Glucose Tolerance
- Trial name
- KFO (NCT00510705)
- Testing
- exercise training, exercise training + metformin, exercise training + glitazone
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- University of Leipzig
Diabetes Mellitus Risk, Obesity
Novel Intervention Linking Public Housing With Primary Care to Prevent Diabetes
(Sisters Health And Primary CarE Uniting and Preventing Diabetes; aka SHAPE UP) will consist of: 1) Neighborhood DPP Intervention: group DPP sessions and individual coaching; 2) Preventive Care Coordination to FQHC: referral…
- Conditions
- Diabetes Mellitus Risk, Obesity, Cardiovascular Risk Factor
- Trial name
- SHAPE-Up (NCT03526237)
- Testing
- 24 week community based DPP Group Lifestyle Balance Program, Wait-List Control community based DPP Group Lifestyle Balance Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Psoriasis, Obesity
Cross-sectional Evaluation of Biological Markers of Cardiovascular Disease in Children and Adolescents With Psoriasis
Hypothesis 1: Patients with psoriasis will have clinical and laboratory assessments differing from control patients. Hypothesis 2: Patients with psoriasis will have laboratory alterations that correlate with other clinical…
- Conditions
- Psoriasis, Obesity, Cardiovascular Risk, Inflammation
- Trial name
- NCT01122095
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Gastrointestinal Diseases, Cardiovascular Diseases
Determining the Potential of Wholegrain Wheat and Rye to Improve Gut HealTh
A dietary intervention study designed as a randomized, controlled, parallel intervention of 6-weeks duration. A total of 75 participants will be included in the study and randomly allocated to one of three interventions (refined…
- Conditions
- Gastrointestinal Diseases, Cardiovascular Diseases, Obesity
- Trial name
- RIGHT (NCT02358122)
- Testing
- Wholegrain rye, Wholegrain wheat, Refined wheat
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity, Cardiovascular Disease
Gastric Sleeve Pilot Study in Morbidly Obese Undergoing Liver Transplantation
The rapid rise in obesity (body mass index (BMI) ≥ 30 kg/m2) in the US over the past decade is responsible for more disease and death than any other single factor.
- Conditions
- Obesity, Cardiovascular Disease, Type 2 Diabetes, Hypertension
- Trial name
- NCT02068872
- Testing
- Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Northwestern University
Hypertension, Obesity
Lifestyle Internet-Based Intervention On Hypertensive Patients With Overweight Or Obesity
This study aims to analyze the effects of a 3 months duration self-applied online program, composed of 9 modules focused on promoting healthy lifestyle habits (healthy eating and increased physical activity), on obese or…
- Trial name
- IBI-HTA (NCT04426877)
- Testing
- Experimental group, Control group
- Where
- Spain
- Volunteers
- 135 people
- Sponsor
- Cardenal Herrera University
Insulin Resistance, Obesity
Integrating the Genetic and Metabolic Faces of Obesity
The goal of this study is to determine why some obese individuals develop insulin resistance and others do not. We hypothesize that an impairment in differentiation of fat cells (adipocytes) is responsible for the development of…
- Conditions
- Insulin Resistance, Obesity, Metabolic Syndrome
- Trial name
- NCT00285844
- Testing
- weight loss, thiazolidinedione
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Stanford University
Postmenopausal, Overweight and Obesity
Markers of Atherosclerosis in Overweight, Postmenopausal Women Following Daily Watermelon Consumption
The primary purpose of this study is to determine the effectiveness of six weeks of watermelon puree supplementation, compared to control (no treatment), on blood antioxidant capacity, inflammation markers in the blood…
- Trial name
- NCT04015544
- Testing
- Watermelon
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Physical Activity
Exercise is Medicine at Emory Seavey Internal Medicine Clinic
Implementation of physical activity promotion in routine health care delivery is low because of multiple barriers including insufficient health system support, care team coordination, and scarcity of community resources for…
- Trial name
- EIM (NCT03416634)
- Testing
- App, Wearable Device, Automated Motivational Message
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Emory University
Diabetes, Hypertension
The Integrated Population (I-POP) Health Trial
The primary aim of this study is to determine whether community health worker (CHW) navigation improves outcomes of chronic disease and chronic disease risk factors in a low-income, primarily ethnic minority population when…
- Conditions
- Diabetes, Hypertension, Chronic Kidney Diseases, Obesity
- Trial name
- I-POP (NCT04761016)
- Testing
- Usual Care, I-POP + CHW navigation
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Diabetes Mellitus, Type 2
Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes
Aim: The United Kingdom Prospective Diabetes Study (UKPDS) showed a reduction in cardiovascular events in obese patients with type-2-diabetes treated with metformin compared with other hypoglycaemic treatments with no difference…
- Trial name
- NCT00118963
- Testing
- Metformin, Insulin BIAsp30 (Novolog 70/30), Repaglinide
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Steno Diabetes Center Copenhagen
Obesity
Additional Effects of Quranic Listening Meditation in Combination With High Intensity Interval Training in Obese Adults
To determine the additional effects of Quranic listening meditation, in combination with High-Intensity Interval Training on cardiovascular fitness and mental health in obese adults.
- Trial name
- NCT06442371
- Testing
- High Intensity interval training + Quranic Listening, High intensity interval training
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Obesity, Hypertension
The Short-Term Effect of a Technology Driven Weight Control (SMART) Program for Obese Adults
The purpose of this study is to evaluate the short-term effect of a technology based weight reduction program for obese (BMI > 30 kg/m2) adults in a primary care office.
- Trial name
- WCPC (NCT00624598)
- Testing
- SMART
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Chronic Care Innovations, Inc.
Obesity, Dyslipidemia
Regulation of Lipoprotein Metabolism in Obese Men
Visceral obesity is strongly associated with dyslipidaemia (hypertriglyceridaemia, low HDL-cholesterol and mildly elevated LDL-cholesterol) and insulin resistance, key characteristics of metabolic syndrome (MetS).
- Conditions
- Obesity, Dyslipidemia, Insulin Resistance
- Trial name
- NCT00392717
- Testing
- Atorvastatin, Fish oils
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The University of Western Australia
Coronary Artery Disease, Peripheral Arterial Disease
Prevention Trial to Achieve Cardiovascular Targets
The objective of IMPACT (Investigation of Motivational Interviewing and Prevention Consults to Achieve Cardiovascular Targets) is to determine the best management strategy for patients undergoing cardiovascular intervention.
- Conditions
- Coronary Artery Disease, Peripheral Arterial Disease, Hyperlipidemia, Hypertension
- Trial name
- IMPACT (NCT01642355)
- Testing
- Prevention Consult, Consult & Behavioral Intervention
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- NYU Langone Health
Cardiovascular Diseases, Diabetes Mellitus
Evaluation of a Letter Intervention Promoting a Plant-based Diet
The researchers' mission is to promote healthier eating behavior and to reduce costs associated with healthcare. The purpose of this study is to evaluate the effects of mailing randomly selected participants a letter promoting a…
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Obesity
- Trial name
- NCT03880838
- Testing
- Personal testimonial, Forks Over Knives Documentary, Commitment nudge
- Where
- United States
- Volunteers
- 11,234 people
- Sponsor
- Geisinger Clinic
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