Clinical trials: Cardiovascular Disease (CVD)
Subarachnoid Hemorrhage in Adult Patients
Sphenopalatine Block in Headache in Patients With Non-traumatic Subarachnoid Hemorrhage
Non-traumatic SAH, linked in 85% of cases to the rupture of an intracranial aneurysm, is a serious stroke affecting young people. Half of all survivors suffer cognitive impairment.
- Trial name
- SATURN (NCT06735261)
- Testing
- Sphenopalatine Ganglion Block using 2% lidocaine
- Volunteers
- 70 people
- Sponsor
- University Hospital, Grenoble
Atherosclerosis
Search a Correlation Between Lp(a) Rate and TFPI Activity in Obese Patients With Chest Pain Like Angina
Atherosclerotic cardiovascular disease is a leading cause of mortality in our countries. Clinically, symptoms could be chest pain suggesting stable angina.
- Trial name
- NCT01290770
- Testing
- blood sample
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Atrial Fibrillation, Stroke
Computerized Decision Support to Prevent Stroke in Atrial Fibrillation
Atrial fibrillation (AF) is the most preventable cause of stroke. However, despite widely available risk stratification tools, numerous options for oral anticoagulation, and evidence-based practice guidelines, anticoagulation for…
- Trial name
- AF-ALERT3 (NCT06355986)
- Testing
- Alert-based computerized decision support
- Where
- 2 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Brigham and Women's Hospital
Severe Heart Failure
Patient Care Management Strategies for Severe Heart Failure in Rhône-Alpes, France.
The heart failure is a chronic pathology with prevalence from 2 to 3% of general population, a death rate of 50% at 6 months for patients with stage IV, and a probability of death or hospitalization or emergency consultation of…
- Trial name
- EFFICARD (NCT02763670)
- Testing
- PRETICARD patient care management, "As usual " patient care management
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Hospices Civils de Lyon
Acute Ischemic Stroke
Safety and Efficacy Study of Remote Ischemic Conditioning Combined With Endovascular Thrombectomy for Acute Ischemic Stroke Due to Large Vessel Occlusion of Anterior Circulation
The purpose of this study is to determine the efficacy and safety of remote ischemic conditioning for patients of acute ischemic stroke who underwent endovascular thrombectomy due to large vessel occlusion of anterior circulation.
- Trial name
- NCT04977869
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 498 people
- Sponsor
- Yi Yang
Trauma, Hemorrhage
Fibrinogen Early In Severe Trauma studY Junior
1. Haemorrhage in severe trauma is a significant cause of mortality and is potentially the most preventable cause of death in paediatric trauma patients 2.
- Conditions
- Trauma, Hemorrhage, Coagulopathy, Pediatrics
- Trial name
- FEISTY Jnr (NCT03508141)
- Testing
- Fibrinogen Concentrate, Cryoprecipitate
- Where
- 10 sites in Australia
- Volunteers
- 44 people
- Sponsor
- Gold Coast Hospital and Health Service
Stroke
Effects of Ecologically Valid VR Task-Oriented Exercises on Post-Stroke Motor and Cognitive Function
Why is this study being done? After a stroke, many people have problems with movement, such as walking, balance, and using their arms and hands.
- Trial name
- RECOVER (NCT07682194)
- Testing
- Conventional occupational therapy, Virtual reality-based exercises in ecologically valid environments
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Hospitales Nisa
Chronic Coronary Syndrome, Coronary Artery Disease
Advanced Invasive Diagnosis for Patients With Chronic Coronary Syndromes Undergoing Coronary ANGIOgraphy (AID-ANGIO)
AID-ANGIO is an observational, prospective, single arm, longitudinal study. Its objective is to investigate the diagnostic yield of the systematic use of a diagnostic strategy hierarchically addressing both obstructive and…
- Conditions
- Chronic Coronary Syndrome, Coronary Artery Disease, Microvascular Angina, Coronary Vasospasm
- Trial name
- AID-ANGIO (NCT05635994)
- Testing
- AID strategy
- Where
- 4 sites in Spain
- Volunteers
- 260 people
- Sponsor
- Hospital San Carlos, Madrid
Arrhythmia, Cardiomyopathy
Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy
The goal of this observational study is to learn about the genetic insights of arrhythmya-induced cardiomyopathy and its clinical prognosis. The main questions it aims to answer are: I.
- Conditions
- Arrhythmia, Cardiomyopathy, Arrhythmia-induced Cardiomyopathy (AiCM)
- Trial name
- UNCHAINED-I (NCT06896266)
- Where
- 4 sites in Spain
- Volunteers
- 109 people
- Sponsor
- Hospital Universitario 12 de Octubre
Essential Hypertension
Study of Bisoprolol (Nerkardou - Nerhadou International) 5 and 10 mg Oral Dissolvable Film (ODF) Treatment in Egyptian Patients With Essential Hypertension
The trial is designed to assess the safety and investigation of the efficacy of a single oral dose of bisoprolol (Nerkardou - Nerhadou) oral dissolvable film (ODF) 5 \& 10 mg, and patients' compliance in the treatment of…
- Trial name
- BETTER (NCT05880056)
- Testing
- Nerkardou (5 mg) & (10 mg)
- Where
- Egypt
- Volunteers
- 406 people
- Sponsor
- Genuine Research Center, Egypt
Transient Ischemic Attack
Korean Transient Ischemic Attack eXpression Registry
This study is to determine the clinical and neuroimaging characteristics of Transient Ischemic Attacks in Korean populations.
- Trial name
- KTX registry (NCT01870531)
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Boramae Hospital
Hypertension, Hypercholesterolemia
Efficacy and Safety of Valsartan and the Combination of Valsartan and Simvastatin
This study will assess and compare the efficacy and safety of valsartan and the combination of valsartan and simvastatin in patients with high blood pressure and high cholesterol.
- Conditions
- Hypertension, Hypercholesterolemia, Dyslipidemia
- Trial name
- NCT00385931
- Testing
- Valsartan and simvastatin
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Novartis
Atrial Fibrillation
Cryoballoon Ablation for Early Persistent Atrial Fibrillation (Cryo4 Persistent AF)
The purpose of this clinical study is to assess the single procedure outcomes of using cryoballoon ablation without additional empirical lesions and/or complex fractionated electrogram (CFE) ablations for patients with early…
- Trial name
- NCT02213731
- Testing
- Holter monitoring
- Where
- 14 sites in France, Germany and 1 more
- Volunteers
- 130 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Stroke
Autologous Hematopoietic Stem Cell Transplantation in Ischemic Stroke
The purpose of this study is to evaluate the safety and efficacy of autologous peripheral hematopoietic stem cell transplantation in ischemic stroke.
- Trial name
- AHSCTIS (NCT01518231)
- Testing
- autologous hematopoiesis stem cell transplantation, Aspirin, Warfarin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhejiang Hospital
Peripheral Artery Disease
Clinical Implications of Peripheral Plaque Morphology
Peripheral Artery Disease involves a buildup of fatty deposits (plaque) within blood vessels that can restrict blood flow. Patients who have PAD and claudication (pain in legs during exercise due to poor blood circulation) may be…
- Trial name
- NCT00578422
- Testing
- Ivus (Intravascular Ultrasound) of Amputation Specimens, IVUS (Intravascular Ultrasound)
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- The Cleveland Clinic
Bypass Complication, Cardioplegia Solution Adverse Reaction
Investigation of Myocardial Protection Level With Specific Cardioplegia Methods in Cardiac Surgery
Investigating the myocardial effects of cold blood cardioplegia and del nido cardioplegia solution, which are routinely used in clinical practice, will contribute to the studies in the literature on the safety and efficacy of…
- Conditions
- Bypass Complication, Cardioplegia Solution Adverse Reaction, Endothelial Degeneration, Oxidative Stress
- Trial name
- NCT05603429
- Testing
- Endocan, E-Selectin, TNF-alpha, Total Oxidant and Antioxidant Status
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
Stable Claudication (Fontaine IIa and IIb), Superficial Femoral Artery Disease
Primary Stenting vs Conservative Treatment in Claudicants - a Study on Quality of Life
The aim of this study is to evaluate whether primary stenting with self expanding stent in patients with peripheral arterial disease suffering from stable claudication due to superficial femoral artery disease results in improved…
- Conditions
- Stable Claudication (Fontaine IIa and IIb), Superficial Femoral Artery Disease, Best Medical Treatment, Quality of Life Scores at 12 and 24 Months
- Trial name
- NCT01230229
- Testing
- Stenting, Best medical treatment
- Where
- 2 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Lund University
Carotid Artery Diseases, Peripheral Artery Disease
Assessment of Carotid Artery Stenosis and Lower Limb Peripheral Ischemia Prior to CABG
From our experience among Egyptian population in our institution, there is an increased prevalence of hidden subclinical peripheral artery disease along with carotid artery affection.
- Trial name
- NCT03516929
- Testing
- carotid duplex, both LL arterial duplex
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Mr Ihab Ali
Cardiac Toxicity, Chemotherapeutic Agent Toxicity
Aerobic Exercise in Patients Receiving Chemotherapy for Cancer
RATIONALE: Aerobic exercise may help prevent side effects caused by chemotherapy and help improve heart health. PURPOSE: This randomized clinical trial is studying the side effects of aerobic exercise and to see how well it works…
- Conditions
- Cardiac Toxicity, Chemotherapeutic Agent Toxicity, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00728429
- Testing
- exercise intervention
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Wake Forest University Health Sciences
Obesity, Cardiovascular Diseases
Naltrexone/Bupropion Cardiovascular Outcomes Study
The purpose of this study is to evaluate cardiovascular (CV) safety of naltrexone hydrochloride (HCl) and bupropion HCl extended release combination (NB) compared with placebo and rule out excess risk of major adverse…
- Trial name
- NCT02638129
- Testing
- Naltrexone HCl/Bupropion HCl ER
- Where
- 139 sites in United States
- Volunteers
- 67 people
- Sponsor
- Orexigen Therapeutics, Inc
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