Clinical trials: Cardiovascular Disease (CVD)
Metabolic Syndrome, Diabetes
Cardiovascular-Kidney-Metabolic Syndrome in Shanghai Zicitizens
The main purpose of this study is to conduct follow-up assessments and update the cardiorenal outcomes among the STONE cohort that was established during 2016-2017.
- Conditions
- Metabolic Syndrome, Diabetes, Obesity and Overweight, Hypertension
- Trial name
- NCT07043166
- Where
- China
- Volunteers
- 4,094 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis
A Multi-center Study on Artificial Intelligence-Based Quantitative Evaluation of Echocardiography
This project aims to collaborate with multiple medical institutions to verify the accuracy, stability, and clinical application value of AI algorithms in echocardiographic quantitative measurement through multi-center clinical…
- Conditions
- Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis, Cardiovascular Diseases (CVD), Echocardiography
- Trial name
- MAIQUEE (NCT07133516)
- Where
- 37 sites in China
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Cardiovascular Diseases (CVD), Cardiac Rehabilitation
Cardio-Fit2: Impact of a Cardiac Rehabilitation Program in Patients With Cardiovascular Disease
Cardiovascular diseases (CVD) are the main cause of morbidity and mortality in the world, being responsible for 17.9 million deaths annually, according to the World Heart Federation (WHF), which represents a significant social…
- Trial name
- Cardio-Fit2 (NCT07098039)
- Testing
- Semi-presential or hybrid group, Hospital Cardiac Rehabilitation
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Virgen de la Luz
Cardiovascular Diseases (CVD)
Swiss Secondary Prevention and Rehabilitation Registry
The SwissPR study is to continuously monitor patient characteristics and short- and long-term benchmark quality measures and outcomes of patients participating in a 12-week ambulatory CR program.
- Trial name
- SwissPR (NCT05500859)
- Testing
- Data collection at Baseline, 3 months after baseline (BL), 1-year follow-up, Telephone follow-up and questionnaire 3 years and 5 years after BL
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardiovascular Diseases (CVD)
Clinical Research on 68Ga-FAPI PET/CMR in Cardiovascular Diseases
FAP-targeted PET imaging using 68Ga-FAPI enables early detection of myocardial fibrosis. Combined PET/CMR provides comprehensive cardiac assessment without extra radiation.
- Trial name
- NCT07063043
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital
CVD, Cardiovascular Diseases
Hoosier Sport: Refining and Implementing a Sustainable Campus-Community Partnership in Rural Indiana
Hoosier Sport is a sport-based youth development program that uses the power of sport to teach children and adolescents sport and leadership skills while promoting health education.
- Trial name
- NCT06602596
- Testing
- Hoosier Sport
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cardiovascular Diseases (CVD), Type 2 Diabetes
Epigenetics and NCD Prevention in Kazakhstan: Personalized Approaches and Biological Age Prediction
This study aims to enhance personalized and preventive care for non-communicable diseases (NCDs) in Kazakhstan by examining epigenetic factors, predicting biological age and reproductive function using machine learning, and…
- Conditions
- Cardiovascular Diseases (CVD), Type 2 Diabetes, Chronic Respiratory Diseases, Obesity (Disorder)
- Trial name
- NCT06953180
- Testing
- Genetic: DNA analysis
- Where
- Kazakhstan
- Volunteers
- 6,720 people, healthy volunteers welcome
- Sponsor
- Asfendiyarov Kazakh National Medical University
Cardiovascular Diseases (CVD), Depression Anxiety Disorder
Effect of Exercise on Tapering Antipsychotics in Patients With Psycho-cardiological Disease(EXTRA-study)
Psycho-Cardiological Disease studies the complex links between the cardiovascular system and emotions. The two diseases are now the focus of public health organizations, forming a vicious circle of mutual influence.
- Trial name
- NCT07025590
- Testing
- Moderate-intensity continuous movement and Antipsychotics intervention, Antipsychotics intervention(sertraline, escitalopram, fluoxetine, duloxetine, paroxetine, venlafaxine, and fluvoxamine)
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Guangdong Provincial People's Hospital
Depression and CVD
Study on the Mechanism of Multi-group Analysis of the Influence of Depression on Common Cardiovascular Diseases
Cardiovascular disease is the main cause of death in the world, accounting for 32% of all deaths. In 2019, the number of people suffering from cardiovascular diseases in the world was about 523 million, of which about 18.6…
- Trial name
- NCT06975592
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Daily Step Count, MASLD
The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.
The study conducted a health survey among Thai adults in 2022 and found a significant increase in obesity and nonalcoholic fatty liver disease (NAFLD), leading to metabolic-associated steatotic liver disease (MASLD).
- Conditions
- Daily Step Count, MASLD, BMI, Metabolic Syndrome
- Trial name
- NCT06334666
- Testing
- Encourage using pedometer
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Mahidol University
Kidney Failure, Chronic, Malnutrition-Inflammation Syndrome
Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients
Patients with kidney failure who require hemodialysis often suffer from anemia (low red blood cell count), heart and blood vessel problems, and a condition involving poor nutrition, inflammation, and hardening of the arteries…
- Conditions
- Kidney Failure, Chronic, Malnutrition-Inflammation Syndrome, Anemia in End Stage Renal Disease, Cardiovascular Diseases (CVD)
- Trial name
- ROXA-HD-MIA (NCT06903559)
- Testing
- Roxadustat, Conventional Anemia Management
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Mansoura University
Diabetes Mellitus, Cardiovascular Diseases (CVD)
Da Qing Offspring Study
This is an observational study tracking families and offspring of three cohorts from the 1986 Da Qing study: newly diagnosed diabetes, impaired glucose tolerance, and normoglycemia groups.
- Conditions
- Diabetes Mellitus, Cardiovascular Diseases (CVD), Offspring, Adult, Impaired Glucose Tolerance (Prediabetes)
- Trial name
- NCT06958640
- Testing
- Lifestyle interventions
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Estrogen Deficiency, Cardiovascular Disease (CVD)
Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women
The purpose of this study is to determine whether young women with functional hypothalamic amenorrhea (premenopausal HypoE) is associated with risk factors for pre-clinical cardiovascular disease (CVD).
- Conditions
- Estrogen Deficiency, Cardiovascular Disease (CVD), Functional Hypothalamic Amenorrhea, Endothelial Dysfunction
- Trial name
- NCT03018366
- Testing
- 17beta Estradiol, Progesterone
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Cardiovascular Diseases (CVD), Drug Effect
Randomized Comparison of Morning Versus Bedtime Administration of Statins: A Cardiovascular Circadian Chronotherapy (C3) Trial
Statins inhibit hydroxy-methylglutaryl coenzyme A (HMG-CoA) reductase which catalyzes the rate-limiting step in cholesterol synthesis.
- Conditions
- Cardiovascular Diseases (CVD), Drug Effect, Atherosclerosis Cardiovascular Disease
- Trial name
- STATIN-C3 (NCT06856772)
- Testing
- Statin in the evening (such as Simvastatin, Atorvastatin, Rosuvastatin, Pravastatin), Statin in the morning (such as Simvastatin, Atorvastatin, Rosuvastatin, Pravastatin)
- Where
- Denmark
- Volunteers
- 42,000 people
- Sponsor
- Tor Biering-Sørensen
Renal Insufficiency, Chronic, Cardiovascular Diseases (CVD)
Guideline-diRected MAnagement for Chronic Kidney Disease: EValuation of an Education Progamme in a National Cluster Randomized Controlled Trial
Study Objective: To evaluate the impact of guideline-based CKD comprehensive management medical re-education for community healthcare providers on improving cardio-renal outcomes in CKD patients.
- Trial name
- GRAVER (NCT06825676)
- Testing
- CKD Patient Management Based on Guidelines
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Guangdong Provincial People's Hospital
Aortic Dissection, Systemic Inflammatory Response Syndrome
Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular Surgery (PANDA VI)
Systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) are the major causes of death in patients with cardiovascular diseases.
- Conditions
- Aortic Dissection, Systemic Inflammatory Response Syndrome, Cardiovascular Diseases (CVD)
- Trial name
- PANDA (NCT06195267)
- Testing
- Sivelestat, Blank control
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Mortality of Patients with CVD, Mortality of Patients with CVD and T2DM
The Impact of Type 2 Diabetes Mellitus on Cardiovascular Events in Saudi Arabia Now and Future
Cardiovascular disease (CVD) and Type 2 diabetes mellitus (T2DM) are major global health challenges with significant morbidity and mortality. In Saudi Arabia, the prevalence of CVD and T2DM is increasing.
- Conditions
- Mortality of Patients with CVD, Mortality of Patients with CVD and T2DM, Mortality of Patients with T2DM, Mortality of Patients with Neither
- Trial name
- NCT06674161
- Volunteers
- 80 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Cardiovascular Diseases, CVD
HEARTWISE - P-CARDIAC for Chinese: Population-based Study
Cardiovascular disease (CVD) is one of the prominent diseases that affect many people. One cost-effective solution is to identify people at higher risk of CVD by CVD risk prediction model.
- Trial name
- HEARTWISE (NCT06262828)
- Where
- Hong Kong
- Volunteers
- 3,800 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cardiovascular Disease (CVD), Hypertension
Veteran Peer Coaches Optimizing and Advancing Cardiac Health
The purpose of this study is to test if having a Veteran peer health coach will improve blood pressure control among Veterans with high blood pressure and at least one other Cardiovascular disease (CVD) risk factor.
- Conditions
- Cardiovascular Disease (CVD), Hypertension, Hyperlipemia, Obesity
- Trial name
- Vet-COACH (NCT02697422)
- Testing
- Community-based peer health coach intervention
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases (CVD)
Healthy Living With Online suPport & Education for Cardiovascular Disease in the Primary Care Setting
This pragmatic four-arm (1:1:1:1) parallel cluster randomised controlled trial (cRCT) aims to evaluate the effectiveness of reducing the risk of cardiovascular disease (CVD) through three combinations of interventions for…
- Trial name
- HOPE-CVD-GP (NCT06099353)
- Testing
- Heart Age, Heart Age-HOPE-CVD App, Communication of Genetic Risk Score
- Where
- Singapore
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University