Clinical trials: Cardiovascular Disease Risk
Myocardial Ischemia, Physical Exercise
Randomized Clinical Trial by Conglomerates on the Efficacy of Maintenance of Physical Exercise in Myocardial Ischemia
Main objective: To assess the efficacy of a phase III cardiac rehabilitation program (CRP), based on counseling in the maintenance of physical exercise (time of physical exercise per week) for patients with myocardial ischemia…
- Trial name
- CarPE3 (NCT04251611)
- Testing
- Maintenance of physical exercise
- Where
- Spain
- Volunteers
- 101 people
- Sponsor
- Núria Santaularia Capdevila
Cardiovascular Risk Assessment, Rheumatoid Arthritis (RA)
Twenty-four Hour Movement Behaviors and Atherosclerotic Risk
This observational study aims to investigate how 24-hour movement behaviors are associated with atherosclerotic risk in adults with rheumatoid arthritis. These behaviors include physical activity, sedentary behavior, and sleep.
- Conditions
- Cardiovascular Risk Assessment, Rheumatoid Arthritis (RA), 24-Hour Movement Guidelines
- Trial name
- PASSARO (NCT07774507)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- São Paulo State University
Pulmonary Embolism
Prognostic Value of Heart-type Fatty Acid-Binding Protein (h-FABP) in Acute Pulmonary Embolism
The patients presenting with acute pulmonary embolism and right ventricular dysfunction are at high risk for life-threatening events and must be identified in the emergency department for adequate care and hospital admission.
- Trial name
- NCT01326507
- Testing
- Dosage de l'h-FABP
- Where
- France
- Volunteers
- 165 people
- Sponsor
- University Hospital, Toulouse
Cardiovascular Diseases, Hyperlipidemia
Home-based Exercise for Management of HIV-associated Cardiovascular Disease Risk
Because of advances in drug treatment, people living with HIV/AIDS (PLWHA) are living longer, but are also at greater risk for cardiovascular disease (CVD) and diabetes.
- Conditions
- Cardiovascular Diseases, Hyperlipidemia, Obesity
- Trial name
- NCT01377064
- Testing
- Physical Activity Group, Standard Care Group
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of South Carolina
Cardiovascular Disease
Effectiveness of Non-pharmacological Interventions in Patients With Cardiovascular Risk Factors in Primary Care
The principal objective is analyzed whether a selective intervention no pharmacological (use of ABPM +/- prescription of physical exercise) for cardiovascular risk factors in patients with high cardiovascular risk in primary…
- Trial name
- NCT03452709
- Testing
- therapeutic exercise, ABPM ambulatory blood pressure monitoring
- Where
- Spain
- Volunteers
- 3,656 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Atrial Fibrillation
Anticoagulation Therapy in the Very Old
This study is designed to evaluate the efficacy and safety of warfarin anticoagulation in the very old and attempt to identify risk factors which may impede safe and effective anticoagulation.
- Trial name
- ATIVO (NCT03103763)
- Testing
- Warfarin
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Robert Stein
Cardiovascular Disease Risk
Remote Ischaemic Preconditioning Combined With Exercise Training on Vascular Function.
Remote Ischaemic preconditioning' (RIPC) is defined as short controlled sequences of repeated inflation of a blood pressure cuff on the upper arm (to reduce blood flow) for 5 mins followed by recovery (cuff deflation so blood…
- Trial name
- NCT03624452
- Testing
- rIPC + Exercise, rIPC only
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Liverpool John Moores University
Heart Failure
Development of a Predictive Algorithm for the Risk of Rehospitalization of Patients With Heart Failure
Heart failure is a chronic disease whose prevalence, due to the aging of the population, is increasing. In France, the prevalence of this pathology is 2.3% (it reaches 10% in the over 75 years) and affects nearly a million…
- Trial name
- NCT03905226
- Where
- France
- Volunteers
- 1,486 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Chronic Coronary Syndrome, Anxiety Disorder
Right Dorsolateral Prefrontal Cortex Closed-loop Neurofeedback for Anxiety in High-ischaemic-risk Chronic Coronary Syndrome
This study is a prospective, randomized, sham-controlled, participant- and assessor-blinded, parallel-group clinical trial designed to evaluate the clinical efficacy, mechanistic effects, and safety of right dorsolateral…
- Conditions
- Chronic Coronary Syndrome, Anxiety Disorder, High Ischemic Risk
- Trial name
- HEART-SET-3 (NCT07543185)
- Testing
- Active right DLPFC closed-loop fNIRS-BCI neurofeedback
- Where
- China
- Volunteers
- 214 people
- Sponsor
- Shenyang Medical College
Cardiovascular Diseases, Diabetes Mellitus
Improving Medication Safety and CVD Risk Factor Control in Kidney Transplant Recipients
There is a lack of data analyzing the influence of Cardio-vascular Diseases (CVD) risk factor control on graft survival disparities in Black transplant recipients.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Medication Adherence
- Trial name
- NCT02763943
- Testing
- Pharmacist-led, technology enabled education intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
Stroke
A TargEted MAnageMent Intervention for Reducing Stroke Risk Factors in High Risk Ugandans
The proposed 2-phase project will first refine the TargetEd MAnageMent (TEAM) intervention to ensure acceptability across a broad range of Ugandans at risk for stroke and then test the effects of TEAM in reducing stroke risk in a…
- Trial name
- TEAM-U (NCT04685408)
- Testing
- TEAM, ETAU
- Where
- 3 sites in Uganda
- Volunteers
- 276 people
- Sponsor
- Case Western Reserve University
Coronary Artery Disease, Genetic Predisposition to Disease
Genetic Risk Stratification for Primary Prevention of CAD in Men and Pre & Post-menopausal Women
The investigators propose to genotype males and females at age 40 years and older, who are asymptomatic and without known heart disease (N=2000).
- Trial name
- NCT05169840
- Testing
- Genetic Risk Score for Coronary Artery Disease
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Multiple Myeloma, Plasma Cell Leukemia
Stem Cell Transplantation To Treat High Risk Multiple Myeloma With Reduced Toxicity Myeloablative Conditioning Regimen
Standard therapy for multiple myeloma (MM) usually includes an autologous bone marrow stem cell transplant - a procedure where the patient is treated with high dose chemotherapy and then their own (autologous) stem cells are…
- Trial name
- NCT00615589
- Testing
- Fludarabine/Busulfan x 4 days, stem cell transplant
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan Rogel Cancer Center
Atrial Fibrillation
READ-POAF Pilot Studies Postoperative Atrial Fibrillation After Cardiac Surgery
Postoperative atrial fibrillation after coronary artery bypass grafting will be monitored up to 1 year after the procedure by implanting a Reveal XT internal loop recorder two weeks before the surgery.
- Trial name
- NCT01530750
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Acromegaly, Growth Hormone Deficiency
Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency
The purpose of the study is to evaluate the effects of growth hormone (GH) replacement in men and women with a history of acromegaly and who are now growth hormone deficient.
- Conditions
- Acromegaly, Growth Hormone Deficiency, Pituitary Disease
- Trial name
- NCT00182091
- Testing
- Recombinant human growth hormone, Saline
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Cardiovascular Diseases, Heart Diseases
Reducing Total Cardiovascular Risk in an Urban Community
PLEASE NOTE: THIS STUDY IS ONLY ENROLLING PATIENTS CURRENTLY BEING TREATED AT BELAIR-EDISON FAMILY HEALTH CENTER. The purpose of this study is to compare the clinical effectiveness and cost effectiveness of two cardiovascular…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Diabetes Mellitus
- Trial name
- COACH (NCT00241904)
- Testing
- Lifestyle Changes, Antiplatelet Agents, Beta Blocker
- Where
- United States
- Volunteers
- 525 people
- Sponsor
- Johns Hopkins University
Visceral Obesity, Non-Alcoholic Fatty Liver Disease
Effect of a Multi-ingredient on Visceral Adiposity and Non-alcoholic Fatty Liver Disease in Individuals With Abdominal Obesity
The aim of this study is to validate the efficacy of specific combination of different natural histidine-related amino acids in the reduction of visceral fat and liver steatosis, as well their associated comorbidities, in…
- Trial name
- FATHIS (NCT05807204)
- Testing
- Multi-ingredient of L-histidine, L-serine, L-carnosine and N-Acetylcysteine
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Aortic Aneurysm
Evaluation of Aortic Aneurysms With Focus on Wall Stress and Wall Rupture Risk
Retrospective study to evaluate the impact of computational wall stress analysis based on computed tomography (CT) of ruptured and not-ruptured aortic aneurysms as an additional predictor for rupture with dedicated software.
- Trial name
- NCT02800876
- Testing
- CT-acquisition
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Hypertension
Olive Leaf Extracts in the Control of Hypertension
This study will be carried out in 2 emergency departments (at the exit of the emergency room) and 2 external consultations (endocrinology of the CHU FB Monastir and diabetology consultation, Jemmal hospital).
- Trial name
- Atherolive (NCT05636826)
- Testing
- atherolive-drug
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir
Atrial Fibrillation
Screening for Atrial Fibrillation With Prolonged Continuous Single-lead ECG Devices in High-risk Patients
Atrial fibrillation(AF) can be asymptomatic and thus left unidentified in many people, but holds potential risk of lethal complications such as stroke and congestive heart failure.
- Trial name
- NCT04519190
- Testing
- Prolonged continuous single-lead ECG monitor, Intermittent ECG monitor, Routine practice
- Volunteers
- 300 people
- Sponsor
- Huashan Hospital