Clinical trials: Cardiovascular Disease Risk Reduction
Coronary Artery Disease, Diabetes Mellitus
Exercise Testing to Screen for Unknown Coronary Artery Disease in Diabetic Patients: Does it Contribute to a Risk Reduction in Very High Risk Patients?
In the present study a cohort of diabetic patients without any symptoms and without known coronary artery disease (CAD) will be screened at the investigators' diabetes outpatients services.
- Trial name
- DADDY-D (NCT00547872)
- Testing
- exercise testing - coronary angiography - revascularization
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- TURRINI FABRIZIO
Multiple Myeloma
UARK 2012-02 Trial For High-Risk Myeloma Evaluating Accelerating and Sustaining Complete Remission
The purpose of this study is to improve the clinical outcomes of research subjects with high-risk multiple myeloma in the context of the immediately preceding Total therapy 5 trial 2008-02 and Total therapy 3 trials 2003-33 and…
- Trial name
- NCT02128230
- Testing
- myPRS, Induction 1 - MEL-10+CFZ-TD-PACE, First Transplant - MEL-80+CFZ-TD-PACE + PBSC (biologic)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arkansas
Cardiovascular Diseases, Coronary Disease
Improving Coronary Prevention in a County Health System
To examine whether the Stanford Health Education and Risk Reduction Training (HEAR2T) program , a case management approach, can be effectively used to manage the risk of coronary artery disease.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Risk Reduction, Heart Diseases
- Trial name
- NCT00128687
- Testing
- risk reduction
- Volunteers
- 419 people
- Sponsor
- Stanford University
Heart Failure With Normal Ejection Fraction, Heart Failure With Reduced Ejection Fraction
Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure
In this single-center, longitudinal observational study, we will comprehensively examine clinical characteristics, proteomic, metabolomic, genomic and imaging data to better understand how different heart failure types may…
- Conditions
- Heart Failure With Normal Ejection Fraction, Heart Failure With Reduced Ejection Fraction, Heart Failure, Right Sided, Heart Failure With Mid Range Ejection Fraction
- Trial name
- PREFER-HF (NCT03480633)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cardiovascular Diseases
Cardiovascular Disease Risk of Awareness
The Cardiovascular Risk Reduction Program (CARDIOREP) aims to raise risk awareness and reduce risk factors.
- Trial name
- NCT06000436
- Testing
- Cardiovascular disease risk assessment, Training and Consultancy, Mobile Application
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Dyslipidemia
Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk
The primary objective was to evaluate the effect of treatment with evolocumab, compared with placebo, on the risk for cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary…
- Trial name
- FOURIER (NCT01764633)
- Testing
- Evolocumab
- Where
- 1,284 sites in United States, Argentina and 47 more
- Volunteers
- 27,564 people
- Sponsor
- Amgen
Overweight and Obesity, Cardiovascular Risk Factor
The Emirates Heart Health Project: A Family-based Diet and Exercise Intervention in Obese and Overweight Patients
Data from Abu Dhabi's Department of Health document that the leading cause of death among the population of the emirate of Abu Dhabi is cardiovascular disease (CVD).
- Trial name
- EHHP (NCT04688684)
- Testing
- Family-based diet and exercise intervention
- Where
- United Arab Emirates
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Cardiovascular Disease Risk Reduction, Chronic Stress
Improving Minority Health Through Biofeedback and Stress Reduction
This study aims to evaluate the effectiveness of a four-week heart rate variability (HRV) biofeedback intervention to improve physiological stress response, emotion regulation, and anxiety-related symptoms in young ethnic…
- Conditions
- Cardiovascular Disease Risk Reduction, Chronic Stress, Anxiety, Emotional Regulation
- Trial name
- NCT07172152
- Testing
- HRV Biofeedback Training
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Amelia Saul, PhD, CTRS, BCB
Phlebitis, Catheter Complications
Evaluation of Proximal Massage and Palm-to-Fist Tapping on Reducing the Risk of Phlebitis
Phlebitis is a clinical condition that develops as a complication of peripheral venous catheter use. Peripheral venous catheterization is a common clinical procedure performed in hospitalized patients, as it provides vascular…
- Trial name
- NCT07703618
- Testing
- Estandard peripheral venous catheter care protocol, Efecto del masaje proximal y del golpeteo de la palma al puño.
- Where
- Colombia
- Volunteers
- 273 people
- Sponsor
- Hospital Universitario San Ignacio
Cardiovascular Risk Factor, Health Behavior
Reducing Cardiovascular Disease Risk in Perimenopausal Latinas
The goal of this study is to pilot test a 12-week behavioral intervention among perimenopausal Latinas (age 40-55 years) that integrates evidence-based education with physical activity, stress management, and coping skills…
- Conditions
- Cardiovascular Risk Factor, Health Behavior, Physical Activity, Self Efficacy
- Trial name
- NCT04313751
- Testing
- Education, Physical Activity, and Stress Management Program, Wait-list
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Atherosclerotic Cardiovascular Disease
A Research Study Looking at How NNC0385-0434 Tablets Work to Lower Blood Cholesterol in People With Heart Disease or a High Risk of Heart Disease
This study looks at how well a new medicine, NNC0385-0434, works to lower blood cholesterol levels. Participants will either get NNC0385-0434 as a tablet (a potential new medicine), or placebo as a tablet (a dummy medicine that…
- Trial name
- NCT04992065
- Testing
- NNC0385-0434 A 15 mg, NNC0385-0434 A 40 mg, NNC0385-0434 A 100 mg
- Where
- 44 sites in United States, Belgium and 5 more
- Volunteers
- 267 people
- Sponsor
- Novo Nordisk A/S
Overweight, Obese
Efficacy of a Web-based Weight Loss Program
Since overweight and obesity, a risk factor for various diseases, is a prevalent problem in the modern society, it is important to search for new strategies to counteract this.
- Trial name
- NCT01634204
- Testing
- KiloCoach, Control
- Where
- 3 sites in Austria, Germany
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Metabolic Syndrome
Cardiovascular Risk Evaluation in Clinical Practice in Metabolic Syndrome Patients
Metabolic syndrome is commonly defined as a set of risk factors and abnormalities that markedly increase the risk of cardiovascular events.
- Trial name
- NCT00171548
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- Novartis
Diabetes, Hypertension
Combined Behavioral and Pharmacological Intervention for Cardiovascular Risk Reduction in Diabetic Patients
The purpose of this research is to study whether a multidisciplinary education in Diabetes and intervention for cardiac risk reduction in a group setting to modify patient behavior and adjust medications can achieve diabetes…
- Conditions
- Diabetes, Hypertension, Dyslipidemia, Coronary Arteriosclerosis
- Trial name
- NCT00357955
- Testing
- Behavioral counseling and peer support, Interactive Education, Role modeling
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Providence VA Medical Center
Moderate Risk of CVD
A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular Disease
The use of acetylsalicylic acid in the primary prevention of cardiovascular events has been extensively studied but to a lesser extent in patients with moderate levels of cardiovascular risk.
- Trial name
- ARRIVE (NCT00501059)
- Testing
- Aspirin (Acetylsalicylic acid, BAYE4465)
- Where
- 466 sites in United States, Germany and 6 more
- Volunteers
- 12,546 people
- Sponsor
- Bayer
Coronary Artery Bypass Graft Redo, Heart Valve Diseases
SONOlysis in Risk REduction of Symptomatic and Silent Brain infarCtions dUring Cardiac surgEry
The aim of the project is to demonstrate a fibrinolytic effect of sonothrombolysis (continual transcranial Doppler monitoring) using 2 MHz diagnostic probe on the reduction of risk of brain infarctions due to the activation of…
- Trial name
- SONORESCUE (NCT01591018)
- Testing
- sonolysis, cardiac surgery
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- University Hospital Ostrava
Carotid Stenosis
Lifestyle Modification Programme for Patients With Asymptomatic Carotid Artery Stenosis
This study randomises patients with patients with asymptomatic carotid artery stenosis, to be managed either by providing an intensive 12-week lifestyle modification programme, or standard healthcare.
- Trial name
- NCT03929354
- Testing
- Risk Factors Modification Programme, Standard Care
- Where
- Ireland
- Volunteers
- 208 people
- Sponsor
- Western Vascular Institute, Ireland
Isolated Systolic Hypertension
Blood Pressure and Lipids Reduction in High Risk Elderly Patients With Isolated Systolic Hypertension
1. Study name: Blood Pressure and Lipids Reduction in High Risk Elderly Patients with Isolated Systolic Hypertension. 2. Medicine: amlodipine/atorvastatin tablet (5mg/10mg) and amlodipine (5mg). 3.
- Trial name
- NCT05165251
- Testing
- Amlodipine/Atorvastatin 5 Mg-10 Mg ORAL TABLET, Amlodipine 5mg, Lifestyle intervention
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Schizophrenic Psychoses, Schizophrenia
Implementation of a Tool for Reduction of Cardiovascular Risk in Patients with Severe Mental Disorders ( HEALTHYHEART )
Observational study of the implementation of a Norwegian adaptation of a tool for monitoring, detection and intervention of cardiovascular risk factors in severe mental disorders.
- Conditions
- Schizophrenic Psychoses, Schizophrenia, Severe Mental Disorder
- Trial name
- HEALTHYHEART (NCT06807242)
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Oslo University Hospital
Cardiovascular Risk Factor, Insulin Resistance
Chronic Cardiovascular Risk Outpatient Management in South Asians Using Digital Health Technology
This platform will enable investigation the cardiovascular risk reduction and the increase in participant engagement in their heart-healthy goals, through the use of virtual care/telemedicine with a digital platform that connects…
- Conditions
- Cardiovascular Risk Factor, Insulin Resistance, PreDiabetes, Diabetes
- Trial name
- HealthPals (NCT03167996)
- Testing
- Use of HealthPals (Telemedicine supported by digital health platform)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stanford University