Clinical trials: Cardiovascular Diseases, completed
Myocardial Infarction
Rapid Diagnosis of Myocardial Damage and Coronary Stenosis With Magnetic Resonance Imaging (MRI)
The hypothesis is that single-shot imaging of myocardial infarction is possible in atrial fibrillation using MRI late enhancement technique
- Trial name
- NCT00188123
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- University Hospital, Linkoeping
Hypertension
VALID: Study to Compare the Reduction of Predialysis Systolic Blood Pressure With Valsartan Compared to Irbesartan in Patients With Mild to Moderate Hypertension on Long-term Hemodialysis
The purpose of the study is to compare the efficacy, safety and tolerability of valsartan 80 mg (with a starting dose of 40 mg) to irbesartan 150 mg (with a starting dose of 75 mg) in patients on long-term haemodialysis with mild…
- Trial name
- NCT00171080
- Testing
- valsartan, irbesartan
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 86 people
- Sponsor
- Novartis
Non-valvular Atrial Fibrillation (NVAF)
A Study to Evaluate the Safety and Effectiveness of Rivaroxaban (Xarelto) for Prevention of Stroke and Systemic Embolism in Indian Patients With Non-valvular Atrial Fibrillation (NVAF)
This study is planned to collect prospective data and evaluate the safety and effectiveness of rivaroxaban for the prevention of stroke and systemic embolism in Indian patients with NVAF when used in clinical practice under…
- Trial name
- XARIN (NCT03887780)
- Testing
- Rivaroxaban (Xarelto,Bay 59-7939)
- Where
- India
- Volunteers
- 504 people
- Sponsor
- Bayer
Diabetic Foot Ulcer
CO2-Laser Treatment in Patients With Diabetic Infected Foot Ulcers
The study is aimed at comparing debridement either with CO2 laser or traditional surgery in patients with infected diabetic foot ulcers. The principal endpoint is bacterial load immediately after treatment.
- Trial name
- DULCIS (NCT02677779)
- Testing
- CO2 laser, traditional surgery
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Cerebral Infarction, Cerebral Infarction Recovery
D-dimer Prognostic Marker of Cerebral Infarction After Revascularization Procedure
Cerebral infarction is the leading cause of acquired disability in adults. Absence of biological marker used in current practice and identified as a prognostic factor for recovery.
- Trial name
- D-Dimer (NCT04938479)
- Testing
- blood sample
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Sickle Cell Anemia, Pulmonary Hypertension
Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension
This study will test whether inhaling nitric oxide (NO) gas mixed with room air can improve pulmonary hypertension (high blood pressure in the lungs) in patients with sickle cell anemia.
- Trial name
- NCT00023296
- Testing
- Nitric Oxide, INO Pulse - NO Delivery System
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Failure, Congestive
Dose Escalation Study of KW-3902 on Diuresis in Subjects With Congestive Heart Failure (CHF).
The purpose of this study is to evaluate the safety of KW-3902IV compared to placebo and to determine the diuretic effect of KW-3902IV compared to placebo in patients hospitalized with volume overload due to CHF who are…
- Trial name
- NCT00159627
- Testing
- KW-3902IV
- Where
- 10 sites in United States
- Volunteers
- 52 people
- Sponsor
- NovaCardia, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Univentricular Heart
Factors Associated With Normal Exercise Capacity in Patients With Single Ventricle
The congenital heart disease (CHD) is the firts cause of congenital birth defects. Medical and surgical advances completely changed the epidemiology of CHD.
- Trial name
- SV (NCT04026542)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Montpellier
Bone Neoplasms
Bonefos and the Consumption of Analgesics
The effect of Bonefos on consumption of analgesics (drugs used for pain treatment) in patients with proven bone metastases.
- Trial name
- BICAM (NCT00909142)
- Testing
- Bonefos (Clodronate, BAY94-8393)
- Where
- Czechia
- Volunteers
- 149 people
- Sponsor
- Bayer
Coronary Artery Disease
High Ticagrelor Loading Dose in STEMI
Ticagrelor is a reversible direct acting P2Y12 antagonist, which has shown to be superior to clopidogrel, in adjunct to aspirin, in preventing recurrent ischemic events.
- Trial name
- NCT01898442
- Testing
- Ticagrelor 180mg, Ticagrelor 270mg, Ticagrelor 360mg
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Florida
Venous Thrombosis, Postthrombotic Syndrome
Ultrasound-enhanced Thrombolysis Versus Standard Catheter Directed Thrombolysis for Ilio-femoral Deep Vein Thrombosis
Patients with deep vein thrombosis (DVT) of the ilio-femoral veins have increased risk for developing post-thrombotic syndrome (PTS) and recurrent venous thromboembolism compared to more distal DVT.
- Trial name
- BERNUTIFUL (NCT01482273)
- Testing
- CDT+US group, CDT-US group
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Tachycardia, Atrioventricular Nodal Reentry
AV Nodal Reentrant Tachycardia Study
The purpose of this study is to determine/identify what mechanisms/factors are involved with regard to AV nodal reentrant tachycardia.
- Trial name
- AVNRT (NCT00618683)
- Testing
- Cardiac Invasive Electrophysiological Study
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Oklahoma
Hypertension
A Quality Improvement Plan for Hypertension Control
The study hypothesis is that the implementation of a plan for quality improvement at the primary care health teams taking care of hypertensive patients, will increase the level of blood pressure control among those patients.
- Trial name
- INCOTECA (NCT00820183)
- Testing
- Quality Improvement plan for Hypertension Control
- Where
- Spain
- Volunteers
- 34,327 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Coronary Artery Disease
A Clinical Trial to Assess the Elixir Medical LithiX Coronary Hertzian Contact Intravascular Lithotripsy Catheter
The objective of the PINNACLE I Clinical Study is to assess safety and performance of the LithiX Coronary Hertzian Contact Intravascular Lithotripsy Catheter (LithiX Coronary HCIVLC; LithiX) to treat moderately to severely…
- Trial name
- PINNACLE-I (NCT05828173)
- Testing
- LithiX Coronary Hertzian Contact Intravascular Lithotripsy Catheter (LithiX Coronary HCIVLC; LithiX)
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 60 people
- Sponsor
- Elixir Medical Corporation
Diabetes, Diabetic Macular Oedema
Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema
The specific aim of the study is to test the following hypothesis: That switching between treatments from bevacizumab to Ozurdex or vice versa in eyes with diabetic macular oedema with no or incomplete response from one therapy…
- Conditions
- Diabetes, Diabetic Macular Oedema, Diabetic Macular Edema, Diabetic Retinopathy
- Trial name
- SwitchDMO (NCT01787669)
- Testing
- Avastin (Bevacizumab), Ozurdex (dexamethasone)
- Where
- 3 sites in Australia
- Volunteers
- 19 people
- Sponsor
- University of Sydney
Neurological Disease
Development, Reliability and Validity of the Telerehabilitation Usability Questionnaire- TrUQ
Neurological diseases are central nervous system diseases that cause an increase in the level of disability and limitations in daily life.
- Trial name
- NCT05970939
- Testing
- Development of the Telerehabilitation Usability Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peripheral Vascular Diseases
Effect of VascuActive Device on Foot Perfusion, Hemodynamics and Exercise Capacity in Patients With PVD & Limb Ischemia
The purpose of this study is to assess the safety and the immediate effect of the VascuActive device on patients with peripheral vascular disease and limb ischemia.
- Trial name
- NCT01014377
- Testing
- VascuActive
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- VascuActive LTD
Cardiovascular Diseases, Coronary Disease
Neighborhoods and CVD Risk in a Multiethnic Cohort - Ancillary to MESA
To investigate if neighborhood characteristics are related to disease risk in a multiethnic cohort.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Atherosclerosis
- Trial name
- NCT00063557
- Sponsor
- University of Michigan
Stroke, Lacunar
Effect of Remote Ischemic Conditioning on Vascular Health in Stroke Patients
The main aim of the current study is to assess cardiovascular effects of remote ischemic conditioning in patients who have suffered from stroke.
- Trial name
- VISP (NCT03635177)
- Testing
- Remote ischemic conditioning
- Where
- 2 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- University of Copenhagen
Cardiac Catheter Ablation, Atrial Flutter
Determination of Catheter Contact by Evaluation of Microelectrode Near-Field Signals
Successful radio frequency (RF) cardiac catheter ablation requires the creation of lesions by delivering energy while maintaining adequate catheter contact with the endocardium.
- Conditions
- Cardiac Catheter Ablation, Atrial Flutter, Cardiac Arrhythmias
- Trial name
- IN-CONTACT (NCT02080975)
- Testing
- Data Collection During Atrial Flutter Ablation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- David B. De Lurgio
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