Clinical trials: Cardiovascular Diseases Risk
Cardiovascular Diseases, Heart Diseases
CVD Risk Factors and Sexual Identity in Women
To examine potential differences in the prevalence and pattern of risk factors for coronary heart disease in a sample of 500 self-identified lesbians and 500 heterosexual women, matched for age, socioeconomic status, and…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease
- Trial name
- NCT00058669
- Volunteers
- 1,174 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Multiple Myeloma
Ixazomib Plus Low-dose Lenalidomide Versus Ixazomib Alone for Maintenance Treatment of High Risk Multiple Myeloma
Ixazomib combined with low-dose lenalidomide(10mg) vs Ixazomib alone as maintenance regimen in patients with high-risk multiple myeloma after induction and consolidation of VRD-based regimen.
- Trial name
- NCT05722405
- Testing
- Ixazomib plus low-dose lenalidomide, Ixazomib
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Diabetes Mellitus, Hypertension
Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow up
The purpose of this study is to identify risk factors for insulin resistance and to investigate the influence of insulin sensitivity on development of cardiovascular risk markers like blood pressure, heart rate, body build…
- Conditions
- Diabetes Mellitus, Hypertension, Ischemic Heart Disease, Stroke
- Trial name
- INFO (NCT01412554)
- Where
- Norway
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Type 2 Diabetes, Vascular Diseases
Phenotyping Individuals With Neo-diagnosed Type 2 Diabetes at Risk for All-cause Mortality
Prevalence of type 2 diabetes (T2D) is increasing worldwide over the last two decades; in these patients the rate of all-cause and cardiovascular (CV) mortality is several folds higher than in the general population, configuring…
- Conditions
- Type 2 Diabetes, Vascular Diseases, Cardiac Disease
- Trial name
- NCT04453605
- Testing
- standard treatments
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Pisa
Blood Pressure, High, Cardiovascular Risk Factor
Efficacy of a Brief Intervention on Reduction of Systolic Blood Pressure
This study examines the efficacy of individualized counseling letters to reduce systolic blood pressure level of ≥ 130 mmHg in individuals aged between 40 and 65 years.
- Trial name
- NCT03077373
- Testing
- Counseling letter
- Where
- Germany
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Obesity, Hyperlipidemia
Effects of Dietary Antioxidants on Cardiovascular Risk Factors
The aim of the Antioxidant Study was to compare the efficacy of foods naturally rich in antioxidants with that of antioxidants in a pill form on markers of inflammation and plasma cholesterol in healthy adults at risk of…
- Conditions
- Obesity, Hyperlipidemia, Hypertension
- Trial name
- NCT00756405
- Testing
- Antioxidant diet, Antioxidant supplement
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Christopher Gardner
Venous Thromboembolism
Comparison of Bleeding Risk Between Rivaroxaban and Apixaban: The Pilot Study
This vanguard pilot study compares rivaroxaban and apixaban, two of the new oral blood thinners for the treatment of blood clots. Half of the patients will receive apixaban and half will receive rivaroxaban.
- Trial name
- COBRRA Pilot (NCT02559856)
- Testing
- Apixaban, Rivaroxaban
- Where
- 4 sites in Canada
- Volunteers
- 71 people
- Sponsor
- Ottawa Hospital Research Institute
Heart Failure
Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device (LVAD) and Medical Management
The purpose of this study is to evaluate and compare the effectiveness of the HeartMate II (HM II) Left Ventricular Assist Device (LVAD) support versus OMM in ambulatory NYHA Class IIIB/IV heart failure patients who are not…
- Trial name
- ROADMAP (NCT01452802)
- Testing
- HM II (HeartMate II LVAD), OMM (Optimal Medical Management)
- Where
- 52 sites in United States
- Volunteers
- 200 people
- Sponsor
- Abbott Medical Devices
Dietary Habits, Risk Factor, Cardiovascular
Sodium Intake in Ecuadorian Population
This study is aim to determine the sodium intake in Ecuadorian population that is an unknown information at present. For that, 24h urine samples will be collected from 130 subjects working either at tue USFQ or HDLV to measure…
- Conditions
- Dietary Habits, Risk Factor, Cardiovascular, Nutritional Disorder
- Trial name
- NCT03154502
- Testing
- Urinary sodium excretion
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad San Francisco de Quito
Diabetes Mellitus, Type 2
Thiazolidinedione Intervention With Vitamin D Evaluation
This study will answer two separate questions. The first question is to test the cardiovascular effects of long-term treatment with rosiglitazone or pioglitazone when used as part of standard of care compared to similar standard…
- Trial name
- TIDE (NCT00879970)
- Testing
- pioglitazone, rosiglitazone, Vitamin D
- Where
- 331 sites in United States, Argentina and 23 more
- Volunteers
- 1,332 people
- Sponsor
- GlaxoSmithKline
Carotid Intima- Media Thickness
A Study to Derive Normative Distribution of CIMT and to Determine Its Correlation With Cardiovascular Risk Factors
This non-interventional, prospective, multi-centric, cross-sectional study is aimed to obtain the distribution of measurements of CIMT in Indian subjects and will involve approx. 30 investigative sites from all over the country.
- Trial name
- Score-India (NCT01551875)
- Where
- 24 sites in India
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET
FAPI PET/CT Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (FAPI-ARVC))
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease associated with fibrofatty myocardial replacement, ventricular arrhythmias, and an increased risk of sudden cardiac death.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET, Cardiac Magnetic Resonance Imaging
- Trial name
- FAPI-ARVC (NCT07563660)
- Testing
- 68Ga-DOTA-SA-FAPI PET/CT
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Istanbul University - Cerrahpasa
Diabetes, Cardiovascular Risk
The Effects of Soy Protein and Isoflavones on Glycemic Control, Insulin Sensitivity and Cardiovascular Risk Factors
The investigators propose to perform a double-blind, randomized placebo-controlled trial to examine the hypothesis that soy protein with isoflavones could improve glycemic control, insulin sensitivity and decrease cardiovascular…
- Trial name
- NCT00856882
- Testing
- soy protein, isoflavones, milk protein
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Blood Pressure Monitoring, Hypertension (HTN)
Community Health Worker Coaching to Reduce Cardiovascular Risk Among Women After a Hypertensive Disorder of Pregnancy
The goal of this clinical trial is to find out whether an enhanced program works better than remote blood pressure monitoring (RBPM) alone for women who had high blood pressure during pregnancy.
- Conditions
- Blood Pressure Monitoring, Hypertension (HTN), Pregnancy
- Trial name
- HERHEART (NCT07457970)
- Testing
- Enhanced Care Group, Remote Blood Pressure Monitoring alone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of South Carolina
Diabetes Mellitus, Type 2
Effects of Vitamin D3 and Prebiotics Supplementation on Cardiovascular Risk Factors in Patients With Type 2 Diabetes
The goal of this randomized, double-blind, placebo-controlled, 6-month supplementation study in individuals with type 2 diabetes is to investigate whether taking daily dietary supplements of vitamin D3 (1600 IU) or prebiotics…
- Trial name
- NCT06351566
- Testing
- Vitamin D3, Prebiotics
- Where
- 2 sites in China
- Volunteers
- 190 people
- Sponsor
- Huazhong University of Science and Technology
Spinal Cord Injury
Cardiovascular Disease Study
Coronary heart disease (CHD) is a leading cause of death in the spinal cord injured (SCI) population, occurring at younger ages than in the able-bodied population.
- Trial name
- NCT00857194
- Testing
- 2 hour Oral Glucose Tolerance Test, Fat Meal Test
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Type 2 Diabetes, Gestational Diabetes
Randomized Trial to Evaluate the Effectiveness of Nurse Case Management
The management of high-risk pregnancies require substantial use of medical resources. Our goal is to determine the effectiveness of a nurse case management program in which case managers are assigned to patients with high-risk…
- Conditions
- Type 2 Diabetes, Gestational Diabetes, Hypertension, Preterm Delivery
- Trial name
- NCT00295256
- Testing
- nurse case manager
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Inherited Cardiac Arrhythmias, Long QT Syndrome
Long Term Monitoring for Risk of Sudden Death
Risk prediction in in inherited heart rhythm conditions that may cause sudden cardiac arrest or death is difficult. Sometimes the risks may be low but the loss of life in an otherwise healthy young individual is catastrophic.
- Conditions
- Inherited Cardiac Arrhythmias, Long QT Syndrome, Arrhythmogenic Right Ventricular Cardiomyopathy, Brugada Syndrome
- Trial name
- NCT04124237
- Where
- Canada
- Volunteers
- 1,051 people
- Sponsor
- University of British Columbia
Healthy Population
Italian Digital Primary Cardiovascular Prevention Study
The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular…
- Trial name
- CV-PREVITAL (NCT05339841)
- Testing
- Mobile health application
- Where
- 32 sites in Italy
- Volunteers
- 27,520 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Cardiovascular Risk Factor, Atrial Fibrillation
The Study of Men Born in 1943
A random sample a random sample of half of all men born in 1943 and living in the city of Gothenburg, Sweden, have been investigated in 1993 at 50 years of age and will be followed continuously with repeated re-examinations and…
- Conditions
- Cardiovascular Risk Factor, Atrial Fibrillation, Congestive Heart Failure, Sleep Apnea
- Trial name
- NCT03138122
- Where
- Sweden
- Volunteers
- 798 people
- Sponsor
- Sahlgrenska University Hospital
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