Clinical trials: Cardiovascular Diseases Risk
Coronary Artery Disease, Atherosclerosis
Measuring Athlete's Risk of Cardiovascular Events 3 (MARC-3)
Regular endurance exercise is widely known to improve cardiovascular health and reduce the risk of heart disease. Yet several imaging studies have shown that male endurance athletes have a higher prevalence of coronary artery…
- Trial name
- MARC-3 (NCT07625488)
- Where
- 2 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Radboud University Medical Center
Coronary Artery Disease
Effect of Digital Technologies on Risk Factor Modification
DigTech investigates the effect of a text message-based intervention to encourage lifestyle change on objective measures of cardiovascular risk in individuals with coronary heart disease (CHD) after percutaneous coronary…
- Trial name
- NCT03871907
- Testing
- Digital technology
- Where
- Russia
- Volunteers
- 700 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Morbid Obesity
Bariatric Surgery and HDL-cholesterol
Objective: to assess the effect of gastric bypass on HDL-cholesterol concentration and its Apolipoprotein A4 content at 1 year following bariatric surgery in comparison with a hypocaloric diet.
- Trial name
- NCT01707771
- Testing
- Roux-en-Y gastric bypass, diet and lifestyle modifications
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Catholic University of the Sacred Heart
Multiple Myeloma
2015-09: a Phase II Randomized, Open-label Study of Anti-signaling Lymphocytic Activation Molecule Monoclonal Antibody During Maintenance Therapy
This study will compare the effectiveness and safety of maintenance therapy with continuous bortezomib, lenalidomide, and dexamethasone (VRD) compared to maintenance therapy that alternates VRD with Elotuzumab, lenalidomide, and…
- Trial name
- NCT03000634
- Testing
- Elotuzumab, Bortezomib, Lenalidomide
- Sponsor
- University of Arkansas
Cardiovascular Events
Social Medical Progression of Coronary Heart Disease With Associated Psychosocial Comorbidity -Interval Rehabilitation.
The purpose of the study is to verfiy the hypothesis if a short intensive psychocardiological interval-intervention, combined with a structured follow up, decreases the rate of disability retirements caused by psychosocial…
- Trial name
- SINKO (NCT01589536)
- Testing
- interval-rehabilitation
- Where
- Germany
- Volunteers
- 480 people
- Sponsor
- Clinic Roderbirken
Breast Cancer, Cardiovascular Risk
Time Restricted Eating in Survivors Trial 2.0
After chemotherapy, older breast cancer survivors experience a faster decline in brain function. This can make it harder to enjoy life, stay social, and maintain independence.
- Conditions
- Breast Cancer, Cardiovascular Risk, Cognitive Function, Physical Function
- Trial name
- TEST2 (NCT07259434)
- Testing
- Time Restricted Eating, Healthy Eating Education
- Where
- Canada
- Volunteers
- 152 people
- Sponsor
- University of Toronto
Cardiovascular Diseases, Cardiovascular Risk Factor
A Mediterranean Diet Nutrition Education Program for the Reduction of Cardiovascular Disease Risk in the Southeastern U.S.
A 12-week, randomized nutrition intervention for the reduction of cardiovascular disease risk factors in a high-risk population in the southeastern United States.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Obesity
- Trial name
- HHP (NCT03683134)
- Testing
- Mediterranean diet, Olive oil and mixed nuts, American Heart Association
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Auburn University
Vascular Death, Myocardial Infarction
Vascular Events In Noncardiac Surgery Patients Cohort Evaluation Study (VISION)
The investigators' study has 4 primary objectives. Among patients undergoing noncardiac surgery the investigators will determine: (1) the incidence of major perioperative vascular events; (2) the optimal clinical model to predict…
- Conditions
- Vascular Death, Myocardial Infarction, Cardiac Arrest, Stroke
- Trial name
- VISION (NCT00512109)
- Where
- 8 sites in Brazil, Canada and 5 more
- Volunteers
- 40,060 people
- Sponsor
- McMaster University
Coronary Atherosclerosis
Evaluation of Subclinical COronary Atherosclerosis for Risk Stratification Using Coronary Computed Tomography (CT) Angiography
To evaluate the prognostic value of coronary CT angiography (CCTA) for risk stratification in asymptomatic adults in comparison with conventional risk stratification (CRS) and coronary artery calcium scoring (CACS).
- Trial name
- ESCORT (NCT01416532)
- Where
- South Korea
- Volunteers
- 5,000 people
- Sponsor
- Seoul National University Bundang Hospital
Lung Neoplasms, Venous Thromboembolism
Venous Thromboembolism in Advanced Lung Cancer
This is a prospective observatory clinical study, aiming to establish and validate venous thromboembolism risk model in Chinese advanced non-small cell lung cancer.
- Trial name
- RIVAL (NCT03581708)
- Testing
- lung cancer
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- Guangdong Provincial People's Hospital
Cardiovascular Disease, Type 2 Diabetes
Health2006 - an Observational Study of Cardiovascular Disease, Diabetes, Asthma and Allergy
The aim is to assess the population prevalence of risk factors for different chronic diseases such as cardiovascular disease, type 2 diabetes, osteoporosis, asthma, and allergy.
- Conditions
- Cardiovascular Disease, Type 2 Diabetes, Asthma, Hypersensitivity
- Trial name
- NCT00316667
- Where
- Denmark
- Volunteers
- 3,471 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
oPAP Should be > 25mmHg in Right Heart Catheterization at Rest, There Should be Patients Who Will Undergo Non-cardiac and Non-obstetric Surgery
Postoperative Morbidity / Mortality Rates of Patients With Pulmonary Hypertension
Pulmonary hypertension (PHT) is an oPAP ≥25 mmHg as assessed by right heart catheterization at rest. It is divided into 5 groups according to its etiology and mechanism.
- Trial name
- PulmonaryHT (NCT05565911)
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Baskent University
Motor Complete Spinal Cord Injury
The Effects of Passive Gait Training in Complete Motor Spinal Cord Injury (SCI)
The purpose of this study is to determine whether a three times per week, 2 month robotic assisted treadmill gait training program, will beneficially affect the fitness, physical and psychological well-being, and the vascular and…
- Trial name
- NCT01349478
- Testing
- LOKOMAT
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Dr. Gabriel Zeilig
Paroxysmal Atrial Fibrillation
Oral Anticoagulation Therapy Pilot Study
The objective of this study is to determine the safety of discontinuing oral anticoagulation therapy in high risk patients who have had a successful cardiac ablation and remain AF recurrence free for 3 months post ablation.
- Trial name
- OAT (NCT01959425)
- Testing
- Off OAT Group (Test), On OAT Group (Control)
- Volunteers
- 80 people
- Sponsor
- Biosense Webster, Inc.
Obesity, Inflammation
Anti-Inflammatory Activities of Grapes in Humans at Risk for Cardiovascular Disease
The goal of the study is to determine whether grape consumption can reduce the risk of cardiovascular disease by reducing the presence of inflammatory molecules and positively altering cholesterol levels, lipid profiles, and…
- Trial name
- NCT01443884
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Pulmonary Edema, Myocardial Infarction
Non-Invasive Ventilation in Pulmonary Edema
This randomized controlled trial is primarily aimed at assessing the rate of acute myocardial infarction with the two noninvasive ventilatory techniques, non-invasive intermittent positive pressure ventilation and non-invasive…
- Trial name
- NCT00453947
- Testing
- CPAP and Non Invasive Ventilation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Ospedale S. Giovanni Bosco
Sudden Cardiac Death
Development of Algorithms to Predict Hemodynamic Instability
Hemodynamic monitoring in hospitalized patients is crucial since in clinical practice unexpected deterioration of cardiovascular function remains a serious problem and an important cause of death.
- Trial name
- NCT01262508
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Thrombosis
Thrombophilic Risk Factors in Pediatric Patients Diagnosed at the Ha'Emek Medical Center
The study will assess the clinical and laboratory data of about 100 pediatric patients diagnosed and treated at the Pediatric Hematology Unit during the years 1980 until 2007 because of thrombotic events.
- Trial name
- NCT00736008
- Testing
- Observational
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- HaEmek Medical Center, Israel
Sleep Apnea Syndromes, Venous Thromboembolism
Sleep Apnea and Tromboembolic Disease
There is some evidence for a hypercoagulable state in sleep apnea-hipopnea syndrome (SAHS), which could play a role in the increased cardiovascular morbility and mortality.
- Trial name
- NCT00501358
- Where
- Spain
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Obesity
Efficacy of a Web-based Lifestyle Modification Program in Obese Patients With Cardiovascular Risk Factors
To evaluate the effect of a 6-month web-based lifestyle modification program with and without telephone counseling versus usual care in obese patients with cardiovascular risk factors on: Weight Loss Waist circumference; blood…
- Trial name
- NCT01664026
- Testing
- Web-based lifestyle modification, Web-based lifestyle modification +
- Where
- Argentina
- Sponsor
- Clínica Bazterrica
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