Clinical trials: Cardiovascular Diseases Risk
Obesity, Cardiovascular Risk Factor
Coordinating Pragmatic Primary Care Population Management for Obesity
The C3PO pilot and feasibility study uses a rigorous, mixed-method research design to provide information needed to refine and implement a technology-mediated primary care outreach intervention approach before conducting a larger…
- Trial name
- C3PO (NCT03998046)
- Testing
- Outreach Support for Weight Loss Goal Setting and Self-Weighing, Outreach Decision Support to Encourage Linkages to Intensive Community Lifestyle Interventions, Adaptive Tailoring of Information Delivery and Intensity of Primary Care Outreach Support
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Diabetes Mellitus
Diagnosis of Coronary Artery Disease in High Risk Diabetic Patients
The aim of this study is to determine in high risk diabetics if the positive predictive value of stress echocardiography is superior to the positive predictive value of stress scintigraphy in the diagnosis of coronary stenosis >…
- Trial name
- NCT00202670
- Where
- 2 sites in France
- Volunteers
- 220 people
- Sponsor
- Société Française de Cardiologie
Multiple Myeloma
A Study of Low Dose Lenalidomide and Dexamethasone in Relapsed/Refractory Myeloma in Patients at High Risk for Myelosuppression
The purpose of this study is to see whether combination of low dose lenalidomide(10mg)+ dexamethasone is equally effective in treating relapsed/refractory myeloma in the group of elderly patients and other patients at risk of…
- Trial name
- NCT00482261
- Testing
- Lenalidomide, dexamethasone, aspirin
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Aortic Dissection
Nordic Consortium for Acute Type A Aortic Dissection-2
The Nordic Consortium for Acute Type A Aortic Dissection-2 (NORCAAD-2) is a multicenter research collaboration involving up to 19 units in the Nordic countries and one in The Netherlands.
- Trial name
- NORCAAD-2 (NCT06862583)
- Testing
- surgery, endovascular intervention
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Karolinska Institutet
Cardiovascular Diseases
Comparison of the Combination of Fenofibrate and 40 mg Simvastatin Versus 40 mg Simvastatin Monotherapy
Mixed or combined hyperlipidemia is a common metabolic disorder characterized by both hypercholesterolemia and hypertriglyceridemia.
- Trial name
- NCT00352183
- Testing
- Fenofibrate/Simvastatin, Simvastatin
- Where
- 67 sites in Australia, Estonia and 4 more
- Volunteers
- 450 people
- Sponsor
- Solvay Pharmaceuticals
Cardiovascular Risk Factor, Hypertension
A Web-based Platform to Conduct Trials of mHealth Apps for Hypertension
Self-management of cardiovascular (CV) risk factors is a recommended form of secondary disease prevention. There are thousands of consumer-facing mobile health (mHealth) applications (apps) intended for tracking, monitoring, and…
- Trial name
- NCT04528654
- Testing
- Mobile Health Application
- Where
- 2 sites in Canada
- Volunteers
- 5 people
- Sponsor
- McMaster University
Thromboembolism
Study to Evaluate a Single Dose of Apixaban in Pediatric Participants at Risk for a Thrombotic Disorder
CV185118 is a single dose Apixaban PK/PD study in pediatric participants. The objective of this study is primarily to study the PK/PD of Apixaban in pediatric participants at risk for thrombosis
- Trial name
- NCT01707394
- Testing
- Apixaban
- Where
- 27 sites in United States, Australia and 3 more
- Volunteers
- 49 people
- Sponsor
- Bristol-Myers Squibb
Phenylketonurias, Cardiovascular Diseases
A Study Into the Future Cardiovascular Disease (CVD) Risk of Phenylketonuria (PKU) Patients on a Low Phenylalanine Treatment Diet (LPD).
This study will assess the cardiovascular disease (CVD) risk in Phenylketonuria (PKU) patients on a low-phenylalanine diet (LPD).
- Trial name
- NCT04251494
- Testing
- Carotid intima media thickness measurement (CIMT), Pulse Wave Velocity measurement, Ankle-brachial pressure index (ABPI)
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Ischemic Stroke, TIA
Colchicine in High-risk Patients With Acute Minor-to-moderate Ischemic Stroke or Transient Ischemic Attack (CHANCE-3)
This study is a multicentre, randomized, double-blind, placebo-controlled, investigator-sponsored study that aims to investigate the efficacy of colchicine in preventing recurrent stroke in the patients with acute…
- Trial name
- NCT05439356
- Testing
- Colchicine
- Where
- 244 sites in China
- Volunteers
- 8,343 people
- Sponsor
- Beijing Tiantan Hospital
Aortic Valve Stenosis
TAVI in LOW RISK in the REAL WORLD
The primary objective is to assess all-cause mortality, the occurrence of stroke, or rehospitalization for cardiovascular causes in low-risk "all-comers" patients following percutaneous aortic valve replacement
- Trial name
- TAVI IN LOW R (NCT07605780)
- Where
- Italy
- Volunteers
- 650 people
- Sponsor
- Centro Cardiologico Monzino
Coronary Heart Disease
A Study of the Effect of RO4607381 on Atherosclerotic Plaque in Patients With Coronary Heart Disease
This study will assess the effect of RO4607381, compared to placebo, on atherosclerotic plaque in patients with coronary heart disease (CHD) including patients with other CHD risk factors.
- Trial name
- NCT00655473
- Testing
- Dalcetrapib (RO4607381)
- Where
- 12 sites in United States, Canada
- Volunteers
- 130 people
- Sponsor
- Hoffmann-La Roche
COVID-19
The Impact of Statin Therapy in the Covid-19 Patients
In the retrospective case series, consecutive COVID-19 patients admitted from June 1 to December 31, 2020, were analyzed. A 1:1 matched cohort was created by propensity score-matched analysis.
- Trial name
- NCT05238402
- Testing
- Statin
- Where
- Turkey (Türkiye)
- Volunteers
- 707 people
- Sponsor
- Antalya Training and Research Hospital
Sodium Excess, Cardiovascular Risk Factor
A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk Factor
This study will evaluate the effect of a short, animated storytelling intervention video on sodium intake as a major risk factor for cardiovascular disease on immediate and medium-term retention of knowledge about the risks of…
- Conditions
- Sodium Excess, Cardiovascular Risk Factor, Education Entertainment Intervention, Short, Animated Storytelling
- Trial name
- NCT05735457
- Testing
- A short, animated storytelling video on dietary sodium
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Preeclampsia, Cardiovascular Risk Factor
Blood Pressure After PREeclampsia/HELLP by SELF Monitoring Study
RATIONALE: Women with a previous history of preeclampsia (PE)/HELLP have a twofold higher risk of cardiovascular disease (CVD) and a fourfold increased risk to develop hypertension at a relative young age.
- Conditions
- Preeclampsia, Cardiovascular Risk Factor, Cardiovascular Diseases, Hypertension
- Trial name
- BP-PRESELF (NCT03228082)
- Testing
- Home Blood Pressure Monitoring (HBPM)
- Where
- 6 sites in Germany, Netherlands
- Volunteers
- 200 people
- Sponsor
- Radboud University Medical Center
Ischemic Stroke
Clinical Registration Trial of Intracranial Stenting for Patients With Symptomatic Intracranial Artery Stenosis(CRTICAS)
This trial is an prospective, government-funded registration study that will observe the safety and effectiveness of intracranial stenting for preventing stroke during a mean follow-up of 12 months in patients with symptomatic…
- Trial name
- NCT01994161
- Testing
- intracranial stenting
- Where
- China
- Volunteers
- 840 people
- Sponsor
- Xuanwu Hospital, Beijing
Primary Cardiomyopathy, Dilated Cardiomyopathy
Risk Stratification in Children and Adolescents With Primary Cardiomyopathy
RIKADA is a prospective study performing systematic family screening including clinical and genetic testing in pediatric patients with primary cardiomyopathy and their first-degree relatives with the aim to facilitate risk…
- Conditions
- Primary Cardiomyopathy, Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy, Left Ventricular Noncompaction
- Trial name
- RIKADA (NCT03572569)
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- German Heart Institute
Cardiovascular Diseases
Effects of Cocoa Products on Cardiovascular Disease Risk Factors
The purpose of this study is to evaluate the effects of optimized composition chocolates that include natural ingredients with demonstrated biological activity are observed cardioprotectores effects in the human.
- Trial name
- CoCD (NCT00511420)
- Testing
- Cocoa product type 1, Cocoa product type 2, Cocoa product type 3
- Where
- Spain
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Hypertension, Cardiovascular Diseases
Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health
High blood pressure (BP) is a serious public health problem responsible for heart attack, stroke and kidney failure. One in four adults in Singapore has hypertension.
- Trial name
- NCT02330224
- Testing
- Hypertension Management Intervention
- Where
- 2 sites in Singapore
- Volunteers
- 100 people
- Sponsor
- Duke-NUS Graduate Medical School
Increased Risk for Cardiovascular Disease
A Multidisciplinary e-Health Program to Promote Regular Physical Activity
In this project, individuals at risk for cardiovascular disease who are looking to lose weight or increase your level of activity, are offered access to an online lifestyle management program.
- Trial name
- NCT02035254
- Testing
- Web-based Wellness Program
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- McGill University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.