Clinical trials: Cardiovascular Diseases Risk
Cardiovascular Disease, Diabetes Mellitus Type 2, Peripheral Vascular Disorder Due to Diabetes Mellitus
Weight Off-loading Training, Cardiovascular Indices, Diabetes
Aims: To evaluate the effectiveness of partial weight-bearing during aerobic exercise training on cardiovascular disease risk and peripheral vascular function in patients with type 2 diabetes mellitus.
- Trial name
- NCT06974422
- Testing
- Partial weight bearing during aerobic exercise training, Full weight bearing during aerobic exercise training, Regular oral anti-diabetic medications.
- Where
- Saudi Arabia
- Volunteers
- 46 people
- Sponsor
- Umm Al-Qura University
Cardiovascular Diseases, Cardiovascular Risk Factor
Qualitative Study of Long Term Cardiovascular Risk Prediction in the Emergency Department
One of the most common presentations to ED is chest pain, with the rapid rule out of heart attacks in the emergency department being common place.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Emergencies
- Trial name
- NCT04601922
- Testing
- Semi-structured interview
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- University of Manchester
Venous Thromboembolic Disease, Pulmonary Embolism and Thrombosis
Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism
A new algorithm derived from only patient age and components of the complete blood count and basic metabolic panel can identify patients discharged from the hospital who may benefit from a blood thinner (called rivaroxaban) to…
- Conditions
- Venous Thromboembolic Disease, Pulmonary Embolism and Thrombosis, Deep Vein Thrombosis, Hospitalism
- Trial name
- eVTE (NCT06232551)
- Testing
- EHR (electronic health record) alert, No EHR (electronic health record) alert
- Where
- United States
- Volunteers
- 152,000 people
- Sponsor
- Scott C. Woller, MD
Acute Coronary Syndrome
A Comparison of the TIMI, GRACE and HEART Scores
Various elements of patient history are checked and entered in the admission Case Recor Form (CRF). Three risk scores are calculated out of these elements, combined with physical examination, laboratory values and ECG-findings.
- Trial name
- HEART (NCT01398631)
- Where
- 10 sites in Netherlands
- Volunteers
- 2,440 people
- Sponsor
- R&D Cardiologie
Obesity
Effect of Wholegrain Wheat on Body Weight and Composition and Cardiovascular Risk
The aim of this study is to investigate the potential beneficial effect of wholegrain on body weight and composition as well as cardiovascular risk in overweight women.
- Trial name
- HEALTHGRAIN (NCT00869531)
- Testing
- wholegrain, refined wheat
- Where
- Denmark
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Preeclampsia, Severe Preeclampsia
Diastolic Dysfunction 2025
This is a prospective observational study conducted at the Maternity and Neonatology Center of Tunis to evaluate cardiac diastolic function in women with preeclampsia compared with normotensive pregnant women.
- Trial name
- NCT07190846
- Testing
- No Intervention (Observational Echocardiographic Evaluation)
- Where
- Tunisia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Sleep, Cardiovascular Risk Factors
Redirecting Poor Sleep Drivers of Early Cardiovascular Disease
Sleep health is a critical component of cardiovascular well-being, and poor sleep has been linked with increased risk for all-cause mortality including cardiovascular disease (CVD).
- Trial name
- NCT06949722
- Where
- Singapore
- Volunteers
- 1,500 people
- Sponsor
- National University of Singapore
Diabetic Foot, Osteomyelitis
Risk Factors for Three Critical Stages of the Diabetic Foot Infections
In this study, it was aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation of the diabetic foot infection in the forward direction without using standard scoring procedures.
- Trial name
- NCT02736253
- Where
- Turkey (Türkiye)
- Volunteers
- 379 people
- Sponsor
- Ege University
Hypertension
Educore Project: Effect of a Visual Learning Method for Improving Blood Pressure Control
Background: High blood pressure (HBP) is a major risk factor for cardiovascular disease (CVD). European hypertension and cardiology societies as well as expert committees on CVD prevention recommend stratifying cardiovascular…
- Trial name
- EDUCORE (NCT01155973)
- Testing
- EDUCORE intervention, Control group
- Where
- 2 sites in Spain
- Volunteers
- 452 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Cardiovascular Diseases, Hypertension
The African-PREDICT Study
The African-PREDICT study aims to (i) generate new knowledge on the early pathophysiology accompanying hypertension development in black South Africans; and (ii) to identify early novel markers or predictors for the development…
- Conditions
- Cardiovascular Diseases, Hypertension, Health Risk Behaviors, Arterial Stiffness
- Trial name
- PREDICT (NCT03292094)
- Where
- South Africa
- Volunteers
- 1,202 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
Coronary Artery Disease, Diabetes Mellitus
Exercise Testing to Screen for Unknown Coronary Artery Disease in Diabetic Patients: Does it Contribute to a Risk Reduction in Very High Risk Patients?
In the present study a cohort of diabetic patients without any symptoms and without known coronary artery disease (CAD) will be screened at the investigators' diabetes outpatients services.
- Trial name
- DADDY-D (NCT00547872)
- Testing
- exercise testing - coronary angiography - revascularization
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- TURRINI FABRIZIO
Diabetes Mellitus
Evaluation of a Structured Nutrition Educational Program in Insulin-treated Diabetic Patients in Vietnam
The purpose of this study is to find out if learning about healthy eating can help people with diabetes control their blood sugar better.
- Trial name
- NCT06985095
- Testing
- Nutrition educational program
- Where
- Vietnam
- Volunteers
- 115 people
- Sponsor
- Cho Ray Hospital
Smoking Cessation
Nicotine Replacement Therapy and Cardiovascular Disease
The aim of this study is to compare the cardiovascular disease event rate in smokers undertaking pharmacologically unaided smoking cessation attempts (the non-exposed group) with the event rate in smokers attempting smoking…
- Trial name
- NCT02195739
- Where
- United Kingdom
- Volunteers
- 61,050 people, healthy volunteers welcome
- Sponsor
- Research in Real-Life Ltd
Hypovitaminosis D, Cardiovascular Diseases
Effect of vitaminD3 or 25(OH)D3 Fortified Dairy on Vitmain D Status and CVD Risk Markers
This study aims to compare the acute effect of consuming milk and butter fortified with either vitamin D3 or 25 (OH) D3 on serum/plasma vitamin D status in humans.
- Trial name
- NCT02535910
- Testing
- vitamin D3, 25(OH) D3, Control
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Reading
Cardiovascular Risk Factors
A Study of Different Types of Fatty Acid on Risk Factors for Heart Disease
Experimental elevation of non-esterified fatty acids (NEFA) impairs endothelial function and insulin sensitivity but the impact of NEFA composition is unknown.
- Trial name
- eFAIRE (NCT01351324)
- Testing
- Absence or presence of fish oil
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Reading
Health Behavior, Cardiovascular Diseases
Prospective, Multicenter Study Assessing a Screening Campaign for Cardiovascular Diseases Risk Factors During SARS-CoV-2 Epidemic
The goal of this prospective study is to evaluate the impact of an innovative screening campagn (using the medical device "CONSULT STATION®" on french population healthcare .
- Conditions
- Health Behavior, Cardiovascular Diseases, Cardiovascular Morbidity
- Trial name
- VACCIPREV (NCT05293379)
- Testing
- Connected teleconsultation booth
- Where
- 4 sites in France
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Elsan
Atherosclerosis
Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events)
Main Study (CACZ885M2301): The purpose of the pivotal phase of this trial was to test the hypothesis that canakinumab treatment of patients with myocardial infarction (MI) at least one month prior to study entry and elevated…
- Trial name
- CANTOS (NCT01327846)
- Testing
- Canakinumab, Standard of care
- Where
- 1,131 sites in United States, Argentina and 38 more
- Volunteers
- 10,066 people
- Sponsor
- Novartis Pharmaceuticals
Metabolic Syndrome
A Study Of Milk Consumption In Metabolic Syndrome
The primary purpose of this study is to determine the impact of whole-fat dairy consumption on cardiovascular and metabolic risk factors and peripheral vascular function in adults with metabolic syndrome.
- Trial name
- NCT07401888
- Testing
- Full-fat diet, Low-fat diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Blood Disease, Anemia, Sickle Cell
Pediatrics:Chlamydia, Sickle Cell Anemia and Stroke Risk - Ancillary to STOP II
To establish a link among Chlamydia infection, sickle cell anemia, and stroke risk.
- Conditions
- Blood Disease, Anemia, Sickle Cell, Chlamydia Infections, Cerebrovascular Accident
- Trial name
- NCT00037388
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Intracranial Aneurysm, Cerebral Aneurysm
PET-imaging of Unruptured Intracranial Aneurysm Inflammation
The main purpose of this study is to determine if PET-imaging can be used to evaluate inflammation level of intracranial aneurysms, thus helping to evaluate the rupture risk of intracranial aneurysm.
- Conditions
- Intracranial Aneurysm, Cerebral Aneurysm, Inflammation
- Trial name
- PET-IA (NCT04715503)
- Testing
- PET imaging, 18F-FDG, PET imaging, 68Ga-DOTANOC
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
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