Clinical trials: Cardiovascular Diseases Risk
Fitness Trackers, Sedentary Time
Fullscale_Intervention Study: Genetic Risk Communication in Coronary Heart Disease and Wearables
Background: This study aims to determine the effects of communicating genetic risk for Coronary Heart Disease (CHD) alone or in combination with goal setting and prompts from a wearable device on objectively measured sedentary…
- Conditions
- Fitness Trackers, Sedentary Time, Genetic Predisposition to Disease, Coronary Heart Disease
- Trial name
- NCT05789966
- Testing
- Genetic Risk Estimate+Health Coaching, Genetic Risk Estimate + Fitbit Functions+Health Coaching
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Multiple Myeloma
Evaluation iNduction, Consolidation and Maintenance Treatment With Isatuximab , Carfilzomib, LEnalidomide and Dexamethasone
A Clinical Phase II, multicenter, Open-label study evaluating iNduction, consolidation and maintenance treatment with Isatuximab (SAR650984), Carfilzomib, LEnalidomide and Dexamethasone (I-KRd) in Primary diagnosed high-risk…
- Trial name
- NCT03104842
- Testing
- Isatuximab, Carfilzomib, Lenalidomide
- Where
- 17 sites in Germany
- Volunteers
- 246 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Phenylketonurias, Cardiovascular Diseases
A Study Into the Future Cardiovascular Disease (CVD) Risk of Phenylketonuria (PKU) Patients on a Low Phenylalanine Treatment Diet (LPD).
This study will assess the cardiovascular disease (CVD) risk in Phenylketonuria (PKU) patients on a low-phenylalanine diet (LPD).
- Trial name
- NCT04251494
- Testing
- Carotid intima media thickness measurement (CIMT), Pulse Wave Velocity measurement, Ankle-brachial pressure index (ABPI)
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
HIV-1-infection, Coronary Microvascular Dysfunction
Improving Coronary Vascular Health in Women
Women with HIV have an increased risk of having a myocardial infarction (heart attack) as compared to women without HIV. One of the mechanisms underlying the increased risk of myocardial infarction among women with HIV may…
- Conditions
- HIV-1-infection, Coronary Microvascular Dysfunction, Metabolic Disease
- Trial name
- INFORM_2 (NCT06843902)
- Testing
- Health Education, Subspecialty clinic referral
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Cardiovascular Diseases, Coronary Disease
Lifetime Risk for Cardiovascular Disease Among Non-White Ethnic Groups
Cardiovascular disease (CVD) is one of the leading causes of death in the United States. Currently, there is little information about the lifetime risk of CVD among non-white ethnic groups.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Failure, Congestive, Atrial Fibrillation
- Trial name
- NCT00377702
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Diabetes, Diabetes Mellitus
Computer-Assisted Cancer Risk Behavior Counseling
To test whether or not giving patients information before their doctor visits changes the care they receive and what type of information is best to give before the doctor visit.
- Conditions
- Diabetes, Diabetes Mellitus, Hypertension
- Trial name
- NCT00242645
- Testing
- Health Information, Preventive Services, Computer tailored information
- Volunteers
- 200 people
- Sponsor
- Thomas Jefferson University
Spinal Cord Injuries
Health Promotion and Cardiovascular Risk Reduction Among People With Spinal Cord Injury
This study is a controlled pragmatic implementation study in clinical practice, with a primary focus on cardiovascular risk reduction through adherence to behavioral interventions related to physical activity and healthy diet.The…
- Trial name
- NCT03689023
- Testing
- A controlled multimodal intervention
- Where
- Denmark
- Volunteers
- 97 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiovascular Diseases, Hypertension
The African-PREDICT Study
The African-PREDICT study aims to (i) generate new knowledge on the early pathophysiology accompanying hypertension development in black South Africans; and (ii) to identify early novel markers or predictors for the development…
- Conditions
- Cardiovascular Diseases, Hypertension, Health Risk Behaviors, Arterial Stiffness
- Trial name
- PREDICT (NCT03292094)
- Where
- South Africa
- Volunteers
- 1,202 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
Heart Diseases
Training Methods for a Doctrine Of Life With Healthy Heart
This study is an interventional study which was conducted in the field. The investigators intended to develop an efficient and economically valuable method which can decrease the risk factors for prevention of cardiovascular…
- Trial name
- NCT00738231
- Testing
- Training
- Where
- Turkey (Türkiye)
- Volunteers
- 498 people
- Sponsor
- Eskisehir Osmangazi University
Cancer Therapy-Related Cardiac Dysfunction, Heart Failure
Risk Stratification of Cancer Therapy-Related Cardiac Dysfunction Using AI-Enhanced Electrocardiography
This study investigates the use of AI-enhanced electrocardiogram (ECG) for risk stratification of cancer therapy-related cardiac dysfunction (CTRCD) before the initiation of cancer therapy.
- Conditions
- Cancer Therapy-Related Cardiac Dysfunction, Heart Failure, Left Ventricular Dysfunction
- Trial name
- NCT07515859
- Testing
- No intervention (retrospective observational study)
- Where
- South Korea
- Volunteers
- 31,486 people
- Sponsor
- Yonsei University
Neoplasms Malignant, Covid19
Thromboembolic Risk Screening in Patients With Cancer and COVID-19
Study Rational Since December 2019, outbreak of COVID-19 caused by a novel virus SARS-Cov-2 has spread rapidly around the world and became a pandemic issue.
- Conditions
- Neoplasms Malignant, Covid19, Thromboembolism
- Trial name
- NEOTHROCOVID (NCT04616846)
- Testing
- Peripheral venous ultrasound
- Where
- 6 sites in France, Monaco
- Volunteers
- 88 people
- Sponsor
- Centre Antoine Lacassagne
Hypertension, Cardiovascular Diseases
China Salt Substitute Study
Cardiovascular disease is a leading cause of death and disability worldwide, and blood pressure is a leading determinant of this risk.
- Trial name
- NCT00145756
- Testing
- low sodium high potassium salt substitute
- Where
- 6 sites in China
- Volunteers
- 600 people
- Sponsor
- The George Institute
Stroke, Plaque, Atherosclerotic
ParisK: Correlation of Imaging Techniques With Histology
The possibility to identify the risk of rupture of a carotid plaque will have tremendous impact in clinical decision making. A vulnerable plaque is considered to have a large lipid rich necrotic core (LRNC), a thin fibrous cap…
- Trial name
- ParisK (NCT01709045)
- Testing
- Magnetic Resonance Imaging (MRI), Dual-Energy Computed Tomography (DECT), Ultrasound
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Colorectal Cancer, Venous Thromboembolism
Risk Factors of Venous Thromboembolism After Colorectal Cancer Surgery
Aim of our study is to find frequency and identify risk factors for venous thromboembolism development in patients who underwent surgery for colorectal cancer.
- Trial name
- NCT06302179
- Where
- Russia
- Volunteers
- 137 people
- Sponsor
- Pirogov Russian National Research Medical University
Cardiovascular Risk Factor
Program of Physical, Nutritional and Psychological Activities With Overweight Schoolchildren
Obesity has been considered as one of the primary factors for the development of pathologies and cardiovascular risk factors. In the child it has been mediator for the development of these comorbidities still in childhood, in the…
- Trial name
- PANPES (NCT03041142)
- Testing
- Interdisciplinary intervention, Routine
- Volunteers
- 33 people
- Sponsor
- Universidade Federal do vale do São Francisco
Cardiovascular Risk Factor
Surveillance of Cardiovascular Risk Factors in Cameroonian Garrison
Purpose: The objective of our study was to assess the cardiovascular risk of a Cameroonian military population and compare it to the cardiovascular risk of the neighboring civilian population.
- Trial name
- NCT04315441
- Testing
- STEPS and AUDIT questionnaires
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- Support and Education Technic Centre
Sleep, Cardiovascular Risk Factors
Redirecting Poor Sleep Drivers of Early Cardiovascular Disease
Sleep health is a critical component of cardiovascular well-being, and poor sleep has been linked with increased risk for all-cause mortality including cardiovascular disease (CVD).
- Trial name
- NCT06949722
- Where
- Singapore
- Volunteers
- 1,500 people
- Sponsor
- National University of Singapore
Obesity, Cardiovascular Diseases
High-intensity Exercise Training or Multidisciplinary Treatment in Extremely Obese Adolescents
The aim of the present study was to determine the effects of a multidisciplinary approach and intensity-controlled interval training on cardiovascular risk factors in overweight adolescents
- Trial name
- NCT00682266
- Testing
- intensity controlled interval training (AIT), Multidisciplinary approach (MTG)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Intracranial Aneurysm
Surgical Management of Complex Intracranial Aneurysms With Hybrid Operating Techniques
To evaluate the clinical benefits and risks of hybrid operating techniques in management of complex intracranial aneurysms, which could coexists with multiple risk factors.
- Trial name
- CIA-HOTs (NCT03206853)
- Testing
- Hybrid Operating Techniques
- Where
- China
- Volunteers
- 258 people
- Sponsor
- liuxingju
Stroke, Ischemic, Stroke Hemorrhagic
The REACTplusNMES Trial: A Double-blinded RCT
The aim of this study is to compare the effectiveness of 6-weeks of reactive balance training (REACT) with and without neuromuscular electrical stimulation (NMES) to paretic lower limb muscles on biomechanical, clinical…
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Cerebrovascular
- Trial name
- REACT+NMES (NCT06127602)
- Testing
- Reactive balance training with Neuromuscular Electrical Stimulation, Reactive balance training without Neuromuscular Electrical Stimulation
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Illinois Chicago
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